Abstract: A method for applying energy to biological tissue. An electromagnetic energy source is directed to apply the energy to a region of the tissue, so as to ablate a portion of the tissue in the region. Preferably, cooling of tissue in the region is initiated subsequent to the ablation.

Abstract: The invention relates to a method of photoeradication of cellular and acellular organisms including the steps of providing a surface acting agent in association with a cellular or acellular organism, the surface acting agent disorienting a membrane structure so that said membrane no longer functions as an effective osmotic barrier; providing a photosensitive material in association with the cellular or acellular organism; and applying light in association with the cellular or acellular organism to cause a disruption of the organism. The method according to the present invention may be utilized in in vitro and in vivo treatment protocols for infections, sterilization procedures, cancer cell eradication, virus and fungus eradication, spore eradication, and biofilm organism eradication. Additional aspects of the invention include particular combinations of photosensitive materials and surfactants for use in photodynamic therapies.

Abstract: A method and apparatus is disclosed for fast precise material processing and modification which minimizes collateral damage. Utilizing optimized, pulsed electromagnetic energy parameters leads to an interaction regime which minimizes residual energy deposition. Advantageously, removal of cumulative pulse train residual energy is further maximized through the rapid progression of the ablation front which move faster than the thermal energy diffusion front, thus ensuring substantial removal of residual energy to further minimize collateral thermal damage.

Abstract: A method and apparatus for treatment of the skin or other biologic tissue includes the ability to subject said skin or other tissue to temperature modulation and radiation, simultaneously. The apparatus that delivers warm or cold material to the treatment site to effect this modulation of temperature may be attached to the apparatus that delivers radiation or it may be a separate entity, that could be utilized with a variety of radiation generating equipment.

Abstract: A liposuction cannula having a source of aqueous solution, a laser source, and a suction source. Aqueous solution is released into an active area within the cannula, and laser energy is directed onto the aqueous solution within the active area to energize the water molecules. The energized water molecules escape from the active area into the surrounding fatty tissue to break down the fatty tissue and release liquid fatty material, which is removed by aspiration via the cannula.

Abstract: A method and apparatus is described for eliminating atherosclerotic vascular disease by exposing the interior of an artery or vein to visible or ultraviolet light of a selected spectrum to thereby sterilize the artery, eradicating infectious pathogens and reverse the pathogenesis of atherosclerotic artery disease. The light energy can be supplied through a fiber optic bundle positioned via an intra-arterial catheter that is connected to an appropriate light radiation source located outside of the body during treatment. In another form of the invention, the light energy is produced by means of a light energy source located at the distal tip of the instrument shaft positioned centrally within the atherosclerotic plaque formation during treatment.

Abstract: A surgical laser probe and system combines a laser diode array remotely connected to a hand-held surgical probe by a fiber bundle. The surgical probe includes a laser head which produces a laser beam for surgical tissue ablation that is delivered through a disposable intraocular probe tip. The probe tip is made of a short section of optical fiber. Preferably, the laser head is an Er:YAG rod pumped by energy from the laser diode array to operate at a wavelength of 2.94 microns. Auxiliary water and thermal electric cooling integral to the hand piece cools the laser head.

Abstract: A light-ray therapeutic apparatus having: a xenon illuminating lamp including a lamp body, a lamp holder provided in the lamp body, a xenon lamp held by the lamp holder, a reflecting mirror for reflecting light emitted from the xenon lamp, and a multilayer film coating-type spectral correction filter provided in a front portion of the lamp body; wherein, of the light from the xenon lamp, energy of ultraviolet rays having a wavelength not longer than 280 nm is cut off by tie spectral correction filter, and spectral coincidence in an ultraviolet wavelength range of 280-400 nm, in a visible wavelength range of 380-780 nm, and in an infrared wavelength range of 780-2,500 nm are made 100±30% respectively, while the spectral coincidence is defined as a ratio of relative energy distribution of the light of the xenon lamp to relative energy distribution of the reference sunlight.

Abstract: A handpiece for projecting laser radiation from a solid-state laser via an articulated arm to biological tissue being treated is disclosed. An optical system in the handpiece provides that the laser radiation is projected in a spot of selectively variable size at a fixed distance from the handpiece. The projected spot can be defined as an image of a characteristic invariant cross-section of the laser beam delivered to the handpiece which has about the same width at a wide range of M2 values of the laser beam. This provides that at any mechanically selected size, the size of the projected spot remains substantially constant over the range of M2 values between about 1 and 15. In one example the handpiece projects 2.94 &mgr;m radiation in a range of spot sizes between about 0.5 mm and 1.5 mm. Spot size remains substantially constant over a range of M2 values between about 1 and 15.

Abstract: A lipoplasty method which includes applying laser energy to the adipose tissue externally through the skin at the same time suction is applied to the targeted tissue. The preferred method includes introducing a solution through an opening in the body to cause the solution to come into contact with adipocytes in the adipose tissue before or simultaneous with applying the laser energy. Optionally, the method can further include reducing inflammation by applying laser energy externally through the skin. Also optionally, the method can include reducing pain by applying laser energy externally through the skin.

Abstract: Use of radiation-absorbing dyes (e.g., indocyanine green (ICG), fluorescein, rose bengal) and photodynamic dyes (e.g., hematoporphyrins, aminolevulinic acids, porphyrins, merocyanines, porphycenes, porfimer sodium, verteporfin, Photofrin II, PH-10, chlorins, zinc phthalocyanine, purpurins, pheophorbides, monoclonal antibody-dye conjugates of any of the foregoing dyes) for the treatment of conditions associated with abnormal vasculature, including, generally, lesions, and, more specifically, tumors (cancerous and benign) and choroidal neovascularization (CNV) associated with age-related macular degeneration (ARMD).

Abstract: A device for the physiotherapeutic irradiation of spatially extensive pathologies by light with the help of a matrix of the sources of optical radiation such as lasers or light diodes placed on the surface of a substrate whose shape is adequate to the shape of the zone of pathology is disclosed. In addition, the device contains stops and a holder to fix the substrate against the bioobject. Additional modules are provided to adjust the temperature, pressure, gas composition over the pathological area. As a source of radiation, chemical reactions accompanied by the luminescence of the products of reaction are suggested. The power supply unit can be autonomous with remote feeding through pulse magnetic field. A supplementary hood optically transparent is provided to localize the pathology as well as the strips that scatter the radiation to get a more uniform bioobject's exposure.

Abstract: The human face is efficiently and precisely dissected while radioifrequency energy is applied to controllably release target tissue bonds and alter surrounding tissues in such a fashion that these facial tissues contract and tighten in response to the energy application while automatically excluding vital nerves and vessels. Tightening will be most dramatic in younger patients between 45 and 55 years of age such that the surgeon may not have to cut-out or stretch skin for a desirable effect in most of this population. The device is inserted through only 3 relatively small 1 cm incisions allowing energy to be applied to the upper subcutaneous, lower dermal and platysmal face-lift layers. The procedures take less than 15 minutes following anesthesia and the effects will last for at least several years.

Abstract: A controlled process for thoroughly curing light-activated surgical and dental composites is presented using a hand-held, self-contained, cordless, rechargeable laser instrument. At least one micro laser generates focused single wavelength blue laser light of at most 480 nm, and enhances efficiency and control of curing. The process of use includes switching from stand-by mode to curing mode of operation of the instrument to save time during surgical and dental procedures.

Abstract: A device is described that can be used by surgeons to provide quick and accurate face-lifting maneuvers that minimize the amount of tissue that has to be removed. The device comprises of a hollow undermining shaft with specially designed tip that can safely separate tissue planes and lyse fibrous tissue. Laser light can be delivered down the shaft to heat and cause tissue contraction. Device can also include a temperature sensor that can be used to control laser power. Optionally the device can also use ultrasound or electrosurgical energy to improve tissue lysing.

Abstract: A medical device is provided which comprises a suction conduit and an energy-transmitting conduit wherein at least some of the transmitted energy is directed to the distal region of the suction conduit. The device may include an optical apparatus for directing the energy. The device has applications in lithotripsy and tissue-removal in a patient.

Abstract: A method and apparatus for treatment for body structures, especially internal body structures involving disorders involving unwanted features or other disorders, that does not require relatively invasive surgery, and is not subject to other drawbacks noted with regard to the known art. A relatively minimally invasive catheter is inserted into the body, treatment of the body structures is applied using the catheter, and the unwanted features or disorders are relatively cured using the applied treatments. The applied treatments can include application of energy or substances, including application of energy (such as of radio frequency energy, microwave energy, or laser or other electromagnetic energy) or substances (such as collagen or other bulking, plumping, or shaping agents; saline or other energy-receiving electrolytes; astringents or other debulking, reducing, or shaping agents; antibiotics or other bioactive, chemoactive, or radioactive compounds).

Abstract: A method for decreasing responsiveness or decreasing resistance to airflow of airways involves the transfer of energy to or from the airway walls to prevent or reduce airway constriction and other symptoms of lung diseases. The treatment reduces the ability of the airways to contract during an acute narrowing of the airways, reduces mucus plugging of the airways, and/or increases the airway diameter. The method provides a longer duration and/or more effective treatment for lung diseases than currently used drug treatments, and obviate patient compliance issues.

Abstract: A quick-connect coupling couples an optical fiber tissue localization device to a light source to cause the forward tip of the device to illuminate. The coupling can be quickly, easily, and reliably mounted to the fiber under operating room conditions. The coupling physically isolates the optical fiber from the light source while optically coupling the fiber to the light source, thereby preventing contamination of the light source by a contaminated optical fiber. The coupling is inexpensive to manufacture, such that the coupling is disposable after a single-patient use.

Abstract: A method and apparatus for processing a material creates a cavitation nucleus in a portion of the material by focusing optical radiation at the portion of the material and then causing mechanical disruption in another portion of the material adjacent the cavitation nucleus by subjecting the cavitation nucleus to ultrasound waves.

Abstract: A device is described that can be used by surgeons to provide quick and accurate face-lifting maneuvers that minimize the amount of tissue that has to be removed. The device comprised of a hollow undermining shaft with specially designed tip that can safely separate tissue planes and lyse fibrous tissue. Thermal radiation can be delivered down the shaft to heat and cause tissue contraction. The device can also include a temperature sensor that can be used to control the thermal radiation. Optionally, the device can also use ultrasound or electro surgical energy to improve tissue lysing.

Abstract: Methods, systems, and kits for treating breast tissue rely on transferring energy to or from cells lining an individual breast duct. Energy can be introduced into the breast duct, e.g., by filling the duct with an electrically conductive medium and applying radiofrequency energy to the medium. Other energy forms could also be used, such as light, ultrasound, radiation, microwave energy, heat, cold, direct current, and the like. By treating individual breast ducts, cancerous and pre-cancerous conditions originating in the duct can be effectively treated.

Abstract: A method for detecting and mapping inflamed zones in living tissues and a device for implementing the method. The method includes subjecting the tissues to be analyzed to a luminous excitation with a predetermined spectral domain, acquiring at least the raw fluorescence signal of the porphyrins for a plurality of measurement points, and in determining, for each measurement point, the intensity of the fluorescence for the wavelengths characteristic of endogenous porphyrins.

Abstract: The present invention provides an improved method of measuring analytes in bodily fluids without the use of a sharp. The method having the steps of irradiating the skin of a patient by focused pulses of electromagnetic energy emitted by a laser. By proper selection of wavelength, energy fluence, pulse temporal width and irradiation spot size, the pulses precisely irradiate the skin to a selectable depth, without causing clinically relevant damage to healthy portions of the skin. After irradiation, interstitial fluid is collected into a container or left on the skin. The interstitial fluid is then tested for a desired analyte to approximate the analyte concentration in other bodily fluids. Alternatively, after the forced formation of a microblister, the epidermis covering the microblister is lysed and the interstitial fluid is subsequently collected and tested.

Abstract: A method for controlled removal of surface tissue layer portions with a non-contact energy delivery modality that applies electrical energy to the targeted tissue surface to cause electrochemical ablation. The system provides (i) a UV energy source for irradiating a beam path through a selected neutral gas environment overlying the targeted tissue thereby creating an ionized gas volume (i.e., a conductive non-equilibrium plasma), and (ii) an electrical source for creating an intense electrical field in the ionized gas volume to thereby apply energy to the targeted surface layer to cause volatilization and removal of the surface layer in a plasma-mediated ablation. The ultrafast plasma creation events are repeated at a high repetition rate to ablate surface layer portions in a controlled manner.

Abstract: A laser treatment apparatus for treating an affected part of a patient by irradiating the affected part with a treatment laser beam. The treatment beam is emitted from a laser source connected to a control unit. A plurality of trigger switches for inputting a trigger signal for starting the emission of the treatment beam and a selection switch for inputting a selection signal for selecting one of the trigger switches are also connected to the control unit. The control unit controls only the trigger switch selected with the selection switch to be enabled.

Abstract: A method and device for inducing or promoting growth and proliferation of skin cells or tissue or for controlling bacterial skin infection is described. The skin cells are irradiated with a low-intensity broad spectrum light at a wavelength of between about 340 to 3,000 nm. The increase in rate of cultivated cells is useful for example to obtain skin-like tissue needed for skin grafts or for promoting healing of skin wounds or lesions. Light-induced skin bacteria control is useful for example in the treatment of bacterial infections of the skin.

Abstract: Wrinkles are cosmetically removed from a superficial area of mammalian skin tissue having an epidermal layer, a basal layer, and a dermal layer, by irradiating the dermal layer through the basal layer, the irradiation being selected to be absorbed by a chromophore in the dermal layer such that collagen present in the dermal layer is heated, while the basal layer remains intact so as to substantially inhibit contact of the dermal layer with ambient air.

Abstract: Evaluation of a laser used in ophthalmologic surgery. A test substrate is formed from a homogenous material of controlled water content that ablates at a rate approximately that of human corneal tissue. A first non-contact surface topographical analysis of the test substrate is performed prior to laser ablation. Laser ablation is performed on the test substrate. A second non-contact surface topographical analysis of the test substrate is performed. The second surface topographical analysis is compared with the first to evaluate the surgical laser. The analysis is used to calibrate the laser. The data also is used to enhance the predictive value of a self-educating neural network. The non-contact surface topographical analysis is performed by rasterstereography, videokeratography, laser holography, scanning laser ophthalmoscope, optical coherence tomography, and scanning white light interferometry.

Abstract: A photosensitizer suitable for use in administering photodynamic therapy (PDT), conjugated with antibodies that are targeted to antigens on abnormal tissue and polyethylene glycol (PEG) or other polymer that extends the residence time of the conjugate within a patient's body. The resulting pegylated targeted conjugate is administered to a patient, and after the antibodies have had sufficient time to bind with the antigens, light from an external or internal source having a waveband corresponding to an absorption waveband of the photosensitizer is administered. Use of an external light source that emits relatively long wavelength light enables the light to pass through any intervening dermal layer and normal tissue between the external light source and the treatment site. Since the photosensitizer in the conjugate is bound to the abnormal tissue, the light therapy has minimal effect on the intervening normal tissue.

Abstract: Fluorescence imaging of tissue is used as a diagnostic tool in which geometric effects and specular reflections are compensated for by normalizing a fluorescence image with a cross-polarized image.

Abstract: A carrier film has one or more openings or wells loaded with a meltable absorbing substance for absorbing laser energy. The carrier film has a clear film which covers one side of the opening containing the absorber substance and the open side of the opening in the carrier film is positioned adjacent to the skin and irradiated through the clear cover film by a laser beam. The melted laser energy absorbing substance is ejected to form a spot laying on the skin. After moving the carrier film, a laser beam impinges the spot thereby raising a tiny blister on the skin containing interstitial fluid. The interstitial fluid is collected for diagnosis and analysis. A method of making and loading the carrier film with a digitally operated dispenser of the type used for ink jet printing is disclosed. Special construction of the opening appears to enhance ejection.

Abstract: A controlled process for thoroughly curing light-activated surgical and dental composites is presented using a hand-held, self-contained, cordless, rechargeable laser instrument. At least one diode laser generates focused laser light, and enhances efficiency and control of curing. The process of use includes switching from stand-by mode to curing mode of operation of the instrument to save time during surgical and dental procedures.

Abstract: A photosensitizer suitable for use in administering photodynamic therapy (PDT), conjugated with antibodies that are targeted to antigens on abnormal tissue and polyethylene glycol (PEG) or other polymer that extends the residence time of the conjugate within a patient's body. The resulting pegylated targeted conjugate is administered to a patient, and after the antibodies have had sufficient time to bind with the antigens, light from an external or internal source having a waveband corresponding to an absorption waveband of the photosensitizer is administered. Use of an external light source that emits relatively long wavelength light enables the light to pass through any intervening dermal layer and normal tissue between the external light source and the treatment site. Since the photosensitizer in the conjugate is bound to the abnormal tissue, the light therapy has minimal effect on the intervening normal tissue.

Abstract: A surgical process for removing the third phalanx of a feline, and most commonly a housecat, while reducing bleeding, swelling, pain and tissue deficit. A circumferential incision is formed on the epidermis of the ungual crest and traction is applied to the epidermis in a cranial direction. This exposes the extensor tendon and synovium, which are incised by the laser from a dorsal position aimed in a palmar direction. While applying traction to the third phalanx in a palmar direction, the collateral ligaments are ablated, permitting further disarticulation of the PII-PIII joint. Finally, the flexor tendon and tissue of the pad are incised by the laser from a dorsal position, permitting removal of the third phalanx. The declaw site is then covered with the redundant epithelium preserved in this process.

Abstract: An apparatus for marking a location within the tissue of a patient includes an optical fiber whose forward end illuminates to facilitate localization of a target tissue by a physician. A strain relief tube is disposed around the outer diameter of the optical fiber adjacent the forward end of the optical fiber. An anchor means, such as a pair of hooks, is mounted to the strain relief tube for engaging the tissue of a patient to secure the tip of the optical fiber within the tissue of the patient. The anchor means is deployed to anchor the tip of the optical fiber in the vicinity of a location desired to be marked. The rearward end of the optical fiber is optically coupled to a light source to transmit light through the optical fiber to illuminate the tip, thereby to facilitate a physician in visually locating the tip.

Abstract: A soft laser unit is described with a housing and a skin resistance measuring device for localizing acupuncture points which contains a probe electrode, a measuring circuit connected therewith and a display device connected to the latter. The unit additionally contains a biostimulation or therapy laser unit, in particular for laser acupuncture, and an exit opening for the laser beam of the laser unit with a focusing optic is provided within the probe electrode, whereby in the state mounted on the patient's skin the laser beam focus of the laser unit comes to lie generally in the plane of the face of the probe electrode, i.e. on the skin surface. The soft laser unit can also be utilized in continuous operation as a so-called “laser shower”, without touching the skin, by fixing the probe electrode in the pressed-in state.

Abstract: In a medical instrument for insertion into an examination subject, as well as a medical examination device or treatment device employing such an instrument, the instrument has an elongated instrument body formed by a number of successively arranged rigid sections, with respective, successive sections being connected to one another via articulated joints which can be angled relative to one another. At least one optical fiber supplied with light is conducted along the instrument body, and at least one fiber Bragg grating is fashioned in the optical fiber in a region adjacent to a joint which is deformed to a degree corresponding to angling of the adjacent sections to the joint, thereby modulating the light in the optical fiber.

Abstract: Output optical energy pulses including relatively high energy magnitudes at the beginning of each pulse are disclosed. As a result of the relatively high energy magnitudes which lead each pulse, the leading edge of each pulse includes a relatively large slope. This slope is preferably greater than or equal to 5. Additionally, the full-width half-max value of the output optical energy distributions are between 0.025 and 250 microseconds and, more preferably, are about 70 microseconds. A flashlamp is used to drive the laser system, and a current is used to drive the flashlamp. A flashlamp current generating circuit includes a solid core inductor which has an inductance of 50 microhenries and a capacitor which has a capacitance of 50 microfarads.

Abstract: A system for producing preferential damage to hair exiting mammalian skin. A agent having an average diameter for enabling the agent to penetrate the hair duct is selected. The agent is designed to attach to, or become physically incorporated into, the hair shaft, the hair follicle, the hair bulb or the hair duct. The agent has an electromagnetic radiation absorption characteristic which enables the agent to absorb a first wavelength of electromagnetic radiation from a skin-penetrating electromagnetic radiation source, such as a laser. The agent is applied to the skin so that the agent penetrates the skin and attaches to or becomes physically incorporated into the hair shaft, the hair follicle, the hair bulb or the hair duct. The agent is exposed to the first wavelength of electromagnetic radiation and absorbs the first wavelength of electromagnetic radiation.

Abstract: A dual mode laser delivery system provides a controllable depth of both ablation and coagulation of an area of skin to be treated. The laser delivery system preferably includes a laser source having a short penetration depth. The controllable ablation depth is achieved by providing an appropriate series of pulses from the laser having an energy and exposure time to achieve ablation of the exposed area of skin to the desired depth. Once ablation of the skin has been performed, a coagulation region to the desired coagulation depth is then generated within the remaining exposed layer of skin by preferably applying a series of one or more very short non-ablative laser pulses at a high repetition rate in order to raise the temperature of the surface of the skin to a desired temperature for a period of time. This series of coagulation pulses will also serve to raise the temperature of the skin under the surface of the skin to a temperature high enough to cause coagulation to the desired depth.

Abstract: Methods and apparatus for dermatology treatment are provided which involve the use of continuous wave (CW) radiation, preheating of the treatment volume, precooling, cooling during treatment and post-treatment cooling of the epidermis above the treatment volume, various beam focusing techniques to reduce scattering and/or other techniques for reducing the cost and/or increasing the efficacy of optical radiation for use in hair removal and other dermatological treatments. A number of embodiments are included for achieving the various objectives indicated above.

Abstract: The present invention features various methods and systems for performing radiation treatment of skin in connection with dynamic cooling of tissue, while minimizing or preventing occurrence of light flash during the treatment.

Abstract: A system for the removal of epidermal and dermal skin through the use of a pressurized stream of water. The surgeon chooses the pressure of the water to obtain the desired abrasive affect. In one embodiment of the invention, a benign abrasive is added to the water to assist in the removal of the surface cells of the skin. In other embodiments, a variety of medications are added to the water such as: anesthetics to deaden the skin being abraded; coagulants to minimized bleeding in the abraded area; and antiseptics to combat infection after treatment is applied. In one embodiment of the invention, a catch reservoir is positioned around the site being treated to collect and withdraw the spent liquid and removed cells.

Abstract: In the present invention a laser treatment system is provided that can be used in any clinical environment without the necessity of personal safety equipment. Furthermore, the present invention provides a large amount of control to the operator/technician and the patient. The present invention combines mechanical and optical methods to protect operators and patients from undesired exposure to laser radiation. According to this approach, safe, portable and fixed embodiments that are useful in a large variety of applications, which are now possible. Several examples are described.

Abstract: A system and method for modification of tissue. The system and method utilize a disposable sample cell that contains a chemical mixture capable of photoinitiation. Upon photoinitiation, a chemical reaction creates electromagnetic radiation that is readily absorbed by a desired portion of tissue. The absorption of energy creates heat which can be controlled to result in predetermined modifications to the tissue.

Abstract: A hand sanitizer generally includes an ozone producing, germicidal ultraviolet lamp for oxidizing organic debris and inactivating bacteria and viruses on the surface and subsurface of hands. In addition, a polychromatic light source is provided for destruction of residual ozone and photoreactivating, or photorepairing, ultraviolet induced effects on the skin. The lamps may be disposed in a free standing housing having a chamber for containing the produced ozone and receiving hands in a vertical orientation. Fans may be provided for circulating the ozone and atmospheric gas throughout the chamber and for evaporating residual moisture from the skin. A light source for destroying excess ozone is also provided which may be operated after the organic debris has been oxidized. Shields are provided within the chamber in order to protect a user's eyes from exposure to the ultraviolet light. The apparatus may be powered entirely by conventional solar panels.

Abstract: The present invention provides an improved method of administering a pharmaceutical composition, such as an anesthetic through the skin of a patient without the use of a sharp or needle. This method includes the step of irradiating the stratum corneum of a region of the skin of the patient using a laser. By a selection of parameters, the laser irradiates the surface of the skin precisely to a selectable depth, without causing clinically relevant damage to healthy proximal tissue. A pharmaceutical composition is then applied to the region of irradiation.

Abstract: The invention relates to a method of treating an infection or sterilization including applying a dye such as methylene blue, toluidene blue, polymyxin B, or combinations thereof to the area of infection or area to be sterilized and exposing the area of infection or area of sterilization with a light having a light wavelength and light dosage and a light dosage rate. The dye may have a concentration ranging from about 10 &mgr;g/ml to about 500 &mgr;g/ml. The wavelength may range from about 610 nm to about 670 nm. The light dosage may range from about 0 J/cm2 to about 200 J/cm2. The light dosage rate may range from about 0 mw/cm2 to about 150 mw/cm2. The treatable infections include staphylococcus, Candida albicans, Escherichia coli, enterococcus, streptococcus, Pseudomanus aeruginosa, Hemophilus influenzae, or E-coli. The invention also relates to an infection treatment kit.

Abstract: An apparatus for measuring an optical characteristic of an ablation standard object having a known ablation rate, as compared with an object to be processed having a unknown ablation rate which is ablated with laser beam, the apparatus comprising a retaining device for retaining the ablation standard object so that a surface thereof may be at the predetermined height, a refractive power measuring device for measuring a refractive power of the ablation standard object, which includes a projecting optical system for projecting target luminous flux for use in refractive power measurement onto the ablation standard object retained by the retaining device and a detecting optical system for detecting the target luminous flux projected by the projecting optical system, a moving device for moving the refractive power measuring device to the predetermined measuring position in order to measure the refractive power of the ablation standard object, and an output device for outputting results measured by the refractive p