Abstract: Systems and methods are provided for reducing intraocular pressure in an eye. A perpendicular incision is made through a conjunctiva of the eye to access a trabecular meshwork of the eye. Electromagnetic energy is focused through the perpendicular incision to ablate a portion of the trabecular network, where said ablation creates a channel for outflow flow of fluid through a sclera venous sinus to reduce pressure within the eye.

Abstract: Wavefront measurements of eyes are typically taken when the pupil is in a first configuration in an evaluation context. The results can be represented by a set of basis function coefficients. Prescriptive treatments are often applied in a treatment context, which is different from the evaluation context. Hence, the patient pupil can be in a different, second configuration, during treatment. Systems and methods are provided for determining a transformed set of basis function coefficients, based on a difference between the first and second configurations, which can be used to establish the vision treatment.

Abstract: An apparatus for ophthalmic laser surgery includes a contact surface for shaping abutment of an eye to be treated, a first radiation-source for making a treatment laser beam available, optical components for directing the treatment laser beam through the contact surface onto the eye, and also a measuring instrument for measuring the depth of the anterior chamber of the eye bearing against the contact surface, whereby the measuring instrument makes measured data available that are representative of the depth of the anterior chamber of the eye at least one point of the same. The apparatus enables a monitoring of the depth of the anterior chamber for a predetermined limiting value being fallen short of and in this way can prevent a dangerous close approach of the posterior surface of the cornea to the anterior surface of the lens when the eye is pressed against the contact surface.

Abstract: A treatment method and apparatus for surgical correction of defective-eyesight in an eye of a patient, wherein a laser device is controlled by a control device, said laser device separating corneal tissue by irradiation of laser radiation to isolate a volume located within a cornea, wherein the control device controls the laser device to focus the laser radiation, by providing target points located within the cornea, into the cornea, wherein the control device, when providing the target points, allows for focus position errors which lead to a deviation between the predetermined position and the actual position of the target points when focusing the laser radiation, by pre-offsets depending on the positions of the respective target points to compensate for said focus position errors.

Abstract: In certain embodiments, a device configured to perform epithelial removal comprises a laser device and a control computer. The laser device can separate the epithelium from the Bowman's layer of an eye using pulsed laser radiation having ultrashort pulses. The laser device includes controllable components that control a focus of the pulsed laser radiation. The control computer controls the controllable components to focus the pulsed laser radiation at one or more epithelial cell layers of the epithelium to photodisrupt at least a portion of the epithelial cell layers.

Abstract: The invention relates to a device for measuring an optical penetration that is triggered in a tissue underneath the tissue surface by means of therapeutic laser radiation which a laser-surgical device concentrates in a treatment focus located in said tissue. The inventive device is provided with a detection beam path comprising a lens system which couples radiation emanating from the tissue underneath the tissue surface into the detection beam path. A detector device generating a detection signal which indicates the spatial dimension and/or position of the optical penetration in the issue is arranged downstream of the detection beam path.

Abstract: A laser system for eye surgery comprises an eye-surgical laser apparatus and a set of interface devices. The eye-surgical laser apparatus has optical components for providing pulsed focused laser radiation with radiation properties matched to the generation of photodisruptions in human eye tissue and a control unit for positional control of the radiation focus of the laser radiation. The control unit is designed for executing various control programs that represent various types of incision figures. Each interface device includes a contact body that is transparent to the laser radiation, with an abutment face for abutment against an eye to be treated, and a coupling portion for detachable coupling of the interface device onto a counter-coupling portion of the laser apparatus. The interface devices differ by virtue of a differing optical effect on the laser radiation provided in the laser apparatus.

Abstract: A method of suturing the lens capsule of the eye in the event of accidental rupture thereof or to create a valve and/or to close a capsulorhexis by laser-induced welding onto the capsule's surface of a flap of biocompatible biological tissue prepared so as to be optically absorbent at the wavelength of the laser being used for welding. The method is suitable for use in so-called Phaco-Ersatz or “lens refilling” ophthalmologic surgery. Welding is desirably performed using laser devices that comprise a laser generator and a fiberoptic system for conveying the laser beam, complete with an applicator handpiece suitable for use in welding the flaps onto the lens capsule in a liquid environment. The handpiece is shaped so as to exert moderate pressure on the tissues to be welded with the free end of the optic fiber.

Abstract: A method and apparatus for performing ophthalmic laser surgery using a pulsed laser beam is provided. The method includes establishing an initial cutting pattern comprising a plurality of original photodisruption points, establishing an enhanced cutting pattern comprising a plurality of enhanced photodisruption points selected to decrease potential adverse effects due to patient movement and having increased density over a fixed area as compared with the plurality of original photodisruption points, and performing an ocular surgical procedure according to the enhanced cutting pattern. Enhanced cutting patterns may include circular cuts around the periphery of a capsule, vertical side cuts for lens fragmentation, raster lamellar cuts, and grid lamellar cuts. Each photodisruption point in the initial cutting pattern and the enhanced cutting pattern comprises a laser target point.

Abstract: An opthalmological device for resolving eye tissue includes a base station with a light source for producing light pulses. Attached to the base station is a supporting arm with an application head that can be placed on an eye. The light pulses are transmitted from the base station through an optical transmission system to the application head. The application head has a light projector for the focused projection of the light pulses for point-by-point resolution of the eye tissue. The supporting arm is rigidly configured and has at one end a rotary joint with a horizontally aligned axis of rotation, wherein the rotary joint is attached in such a way that the application head can be placed on the eye with a rotation about the axis of rotation. The rotary joint makes it possible for the application head or the light projector to be manually docked in a controlled manner onto the eye in the vertical direction by means of a rotational movement that is easy to perform and has low mechanical friction.

Abstract: The present invention relates to a femtosecond laser ophthalmological apparatus and method that creates a flap on the cornea for LASIK refractive surgery or for other applications that require removal of corneal and lens tissue at specific locations such as in corneal transplants, stromal tunnels, corneal lenticular extraction and cataract surgery. The femtosecond laser is transferred to a hand piece module via a rotating mirror arm module. In the hand piece, the femtosecond laser beam is scanned into overlapping circles of laser pulses which are then moved in an overlapping trajectory on a patient's eye to ablate the eye tissue in a predetermined pattern.

Abstract: A curve information acquisition unit configured to acquire information on a shape of a curvature changing portion of which a radius of curvature changes according to a predetermined function, a driving support unit configured to perform driving support for the driver at the time when the vehicle moves in the curvature changing portion, and a driving support control unit configured to decide timing at which the driving support unit performs driving support, based on the information on the shape of the curvature changing portion acquired by a curvature changing information acquisition unit.

Abstract: A method and apparatus for a refractive surgical treatment that uses a laser which produces a succession of laser pulses applied to a material region. The laser pulses irradicates the material region to be divided where the energy of the individual pulse in less than the energy required to produce the material division or cutting.

Abstract: The present invention refers to a Laser therapy system and a method for a treatment of a cornea and/or sclera of an eye to correct its refractive system, comprising: a dispenser for a photosensitizer agent; a 3D imaging unit; an image processing unit adapted to recognize a first collagen tissue structure and a first orientation of respective collagen fibers therein; a UVA light source adapted to a crosslinking within the collagen tissue structure; an optical system for deflecting and focusing the UVA light on a focus point behind an aperture within the imaging volume; and a processing and control unit adapted to receive data relating to a refractive error of the eye, to determine a second collagen tissue structure with new corrective collagen crosslinks, such as to achieve a minimized refractive error of the eye and a UVA light energy to induce the new corrective collagen crosslinks.

Abstract: The invention relates to methods of treating an eye that include coupling a suction ring to the eye and introducing a liquid into an interior chamber of a container element coupled to the suction ring. The container element is also coupled to a focusing lens of a laser system such that only the liquid within the interior chamber is positioned between the focusing lens of the laser system and an outer surface of the eye. In some embodiments, the suction ring has a first suction region that is designed to suck the suction ring onto an eye and a second suction region that is designed to couple the suction ring to the container element.

Abstract: Embodiments of the present invention encompass systems and methods for customized vision treatments that account for effects associated with corneal flap creation.

Abstract: An ophthalmological device (1) includes an optical transmission system (5) for transmitting femtosecond laser pulses (L) onto a projection lens (3) for projection onto or into the eye tissue (21). The device (1) also includes a lens interchange device (4) designed for interchanging and connecting different projection lenses (3) to the optical transmission system (5). The lens interchange device (4) includes a number of different projection lenses (3) which are connected mechanically to one another and which can be fed to the optical transmission system (5) by a rotational or translational movement in order to connect the former to the optical transmission system (5). The lens interchange device (4) makes it possible for a user to flexibly and efficiently change the projection lens (3) so that the projection lens (3) can be changed or altered without great expenditure of time and without using a varifocal lens, even between different applications and treatment steps.

Abstract: There is provided a system, apparatus and methods for developing laser systems that can create precise predetermined clear corneal incisions that are capable of reducing induced astigmatism. The systems, apparatus and methods further provide laser systems that can provide these incisions at or below Bowman's membrane.

Abstract: A planning system for generating control data, a treatment device for ophthalmic surgery to correct refraction, and a method for generating control data for such a treatment device, by which method it is easily possible to continue an interrupted treatment or correct a previous treatment. To this end, the planning system has calculating means for defining a corneal incision surface, wherein the calculating means determine the new corneal incision surface such that the existing corneal incision surface is incised by at least a part of the new corneal incision surface at an angle of between 60° and 120°.

Abstract: Systems and methods related to corneal ablation for treatment of one or more high-order optical aberrations are provided. A method includes providing a defect-correcting prescription, determining an ablation profile to impose the prescription on the cornea, and determining a sequence of laser-energy ablations to impose the ablation profile on the cornea. The prescription comprises a high-order optical correction. The ablation profile includes a first-segment profile and a second-segment profile. The second-segment profile corresponds to at least one high-order optical correction. The ablation sequence includes applying ablations corresponding to the first-segment profile prior to applying ablations corresponding to the second-segment profile.

Abstract: A method of accurately fabricating a non-human donor corneal tissue for implantation into a recipient human cornea, the method comprising the steps of: removing corneal tissue from a donor with a femtosecond laser; placing the corneal tissue in a fixative solution for a selected time interval to cross-link the collagen fibrils in the tissue and prevent swelling of the corneal tissue; and shaping the tissue to provide a conical inlay of a selected shape and thickness having one or more radial extensions. The method is such that the corneal inlay may be attached to the peripheral corneal and/or the sclera. The method is such that the corneal inlay may be stored for a period of up to two years prior to attachment.

Abstract: An apparatus, such as lenses, a system and a method for providing custom ocular aberrations that provide higher visual acuity. The apparatus, system and method include inducing rotationally symmetric aberrations along with an add power in one eye and inducing non-rotationally symmetric aberrations along with an add power in the other eye to provide improved visual acuity at an intermediate distance.

Abstract: An apparatus to treat a patient comprises a laser beam, a measurement module, a scanner and a curved patient interface lens. The curved patient interface is measured with a pattern so as to determine a plurality of distances of the curved surface at a plurality of measurement locations. The measurement pattern may comprise the plurality of measurement locations distributed about a central measurement axis corresponding to the laser treatment axis. The plurality of measurement locations of the curved surface may correspond to a portion of a planned treatment profile, such that the measured distances correspond to alignment of the planned treatment. The plurality of distances can be used to determine an apex of the curved surface of the patient interface and to align the laser treatment axis with the apex of the curved surface.

Abstract: An ophthalmological laser system and operating method wherein laser-supported operative interventions can be achieved with higher accuracy. The cornea is irradiated with an ophthalmological laser and a detection light confocally recorded, the cornea being scanned in three-dimensions by irradiation with an illuminating laser power using a scanner unit along several directions at several points. Using the simultaneously recorded detection light the position and/or shape of a posterior boundary surface of the cornea is determined. A lamella parallel to the posterior boundary surface can then be cut.

Abstract: Methods, software, and systems are provided for determining an ablation target shape for a treatment for an eye of a patient. Techniques include determining wavefront information from the eye of the patient with a wavefront eye refractometer, determining anterior corneal shape information from the eye with a corneal topography device, and combining the wavefront information and the anterior corneal shape information to determine the ablation target shape.

Abstract: A system and method for altering the shape of a lamina of transparent material (e.g. the cornea of an eye), as it is being subjected to a transverse pressure differential, requires a computer controlled laser unit. In accordance with specified input parameters, the computer directs the laser unit to perform LIOB over predetermined surfaces within the lamina. This weakens the material for a desired reshaping of the lamina in response to the pressure differential. With respect to a perpendicular axis that is defined by the lamina, surfaces parallel to the axis (e.g. cylindrical surfaces) are separated from each other by about two hundred microns. For surfaces perpendicular to the axis, the separation is about ten microns. In each instance, the cuts that result from LIOB are only about two microns thick.

Abstract: An apparatus for refractive ophthalmic surgery by laser radiation including a source of radiation which emits a processing beam a beam path for focusing and scanning. The beam path focuses the processing beam into a cornea of an eye and shifts a position of a focus therein. A beam splitting device generates several foci in the cornea and divides the processing beam into a primary beam and at least one secondary beam. The primary and secondary beams have substantially the same cross section as the processing beam which is incident on the beam splitting device and the beam-splitting device introduces a separation between the primary and secondary beams. The primary and secondary beams expand in the beam path. A contact glass induces a pre-defined geometric boundary surface at the cornea.

Abstract: A device for controlling a laser therapy of the eye, including an evaluation unit that determines an intensity of a transient temperature effect by analysis of interferometric signals obtained from the eye and a control unit that controls the laser therapy, which is based on said transient temperature effect, the control unit being connected with said evaluation unit. A method for controlling a laser therapy of the eye, includes determination of the intensity of a transient temperature effect that is utilized for the control of the laser therapy, based on the effect, by analysis of interferometric signals.

Abstract: Described is an eye treatment device having a radiation source, the light emitted by the radiation source having such a wavelength range that it brings about a reaction in a treatment region of an eye and is absorbed, at least partially, in at least one of the regions located behind same in the direction of the retina that are in front of the retina. The light emitted by the radiation source can have a wavelength range in which the treatment region is partially transmissive. The treatment region can be the cornea. The reaction brought about in the treatment region by the light can be an ablation of tissue. The reaction brought about in the treatment region by the light can also be a laser-induced optical perforation of tissue, which is also referred to as photo-disruption. The radiation source can be a laser source.

Abstract: Systems, methods, and computer program products are provided for the administration of ablation profiles during refractive surgery treatments. Basis data framework techniques enable the implementation of ablation profiles having various shapes, resulting in increased ablation efficiency when treating certain vision conditions. Exemplary basis data architecture approaches are configured to efficiently operate with annular, elliptical, and slit laser beam shapes, for example, and to account for position-dependent ablation features.

Abstract: A planning unit produces control data for a treatment device for eye surgery which produces at least two cutting planes in a cornea of the eye using a laser unit. The planning unit includes a calculation module for establishing cornea cutting planes and is configured to establish the cornea cutting planes based on data of a refraction correction. The cornea cutting planes are determined so as to include a cap cut, a lenticule cut, a first access cut for accessing the cap cut, and a second access cut for accessing the lenticule cut. The planning unit is also configured to produce a control data set for actuating the laser unit for the cornea cutting planes.

Abstract: A planning system generates control data for a treatment device for eye surgery that creates at least two incision surfaces in the cornea using a laser apparatus. The planning system includes a computation device configured to specify the cornea incision surfaces based on data of a refractive correction. The cornea incision surfaces include an access incision and a cap incision, with the access incision having a smaller diameter than the cap incision. The computation device being configured to generate a control data record for the cornea incision surfaces for purposes of controlling the laser apparatus.

Abstract: A photo detector is selectively coupled to a first integrator or a second integrator with switching circuitry when the laser pulses. An integration time of the signal from the photo detector can be substantially greater than an amount of time between successive laser beam pulses in order to provide an accurate measurement of each laser beam pulse of a high repetition rate pulsed laser. The laser may comprise a clock coupled to an optical switch of the laser system, and control circuitry can control switching and coupling of the detector to the first integrator or the second integrator in response to the clock signal. The first integrator and the second integrator can be selectively coupled to an output such that the first integrator or the second integrator is coupled to the output of the energy detection circuitry when the other integrator is coupled to the detector.

Abstract: A device for machining the human cornea with focused laser radiation includes controllable components for setting the location of the radiation focus, a control computer for controlling these components, and also a control program for the control computer. The control program contains instructions that have been designed to bring about, upon execution by the control computer, the generation of incisions in the cornea in accordance with a predetermined incision figure, the incision figure defining a corneal bed, a flap situated on the bed and also at least one tissue strip situated in the region of the peripheral edge of the flap between the bed and the flap and extending along the edge of the flap. After the flap has been folded away, the tissue strip has to be removed and enables a creaseless post-ablative close fitting of the folded-back flap against the surface of the bed. In this manner, microstriae which may impair the visual capacity can be avoided.

Abstract: Systems and methods for modifying an eye including a light source with light elements, a photodetector producing a signal representing images of the light elements and corresponding to locations on an ocular surface, an optical system directing light from the light elements reflected by the ocular surface onto the photodetector, a memory including code for processing the signal, and a processor for executing the code and outputting shape data for use in calculating a treatment plan for the eye. The code includes instructions for determining the shape data based on a combination of zonal reconstruction and polynomial fitting using the plurality of images.

Abstract: A technique for detecting and providing alerts or indications that can be used for controlling or altering the displacement speed of an applicator coupling skin heating energy across a treated skin. A temperature sensor monitors the rate of skin temperature change and provides feedback related to altering the applicator displacement speed according to the rate of skin temperature change. Disclosed is also an applicator for implementing this method.

Abstract: A side firing laser device suitable for use in medical and surgical procedures has a laser energy transmission efficiency in excess of 90% and provides consistent and rapid vaporization of tissue as well as long useful life. The device includes a conduit with an optical fiber therewithin. The optical fiber is adapted for coupling to a laser energy source at the proximal end thereof and has a beveled distal end portion capped by a closed end capillary tube which, in turn, is surrounded by a reflective sheath with a side port through which laser energy emitted by the optical fiber can pass.

Abstract: A planning device generating control data for a treatment apparatus for refraction-correcting ophthalmic surgery is provided, said apparatus using a laser device to separate a corneal volume, which is to be removed for correction, from the surrounding cornea by at least one cut surface in the cornea of an eye, said planning device comprising an interface for receiving corneal data including information on pre-operative cuts which were generated in a previous ophthalmic operation, and computing means for defining a corneal cut surface which confines the corneal volume to be removed, said computing means defining the corneal cut surface on the basis of the corneal data and generating a control dataset for the corneal cut surface for control of the laser device.

Abstract: A method for providing vision correction to a patient. The method includes: (a) measuring the degree of vision correction needed by the patient and determining the location and shape of refractive structures that need to be positioned within the cornea to partially correct a patient's vision; (b) directing and focusing femtosecond laser pulses in the blue spectral region within the cornea at an intensity high enough to change the refractive index of the cornea within a focal region, but not high enough to damage the cornea or to affect cornea tissue outside of the focal region; and (c) scanning the laser pulses across a volume of the cornea or the lens to provide the focal region with refractive structures in the cornea or the lens. Again, the refractive structures are characterized by a change in refractive index, and exhibit little or no scattering loss.

Abstract: Systems, devices, and methods for correcting presbyopic vision create a dye ring in the cornea. The intrastromal ring is created using a femtosecond laser and is centered on the visual axis. A black or a colored pigment is then injected. The internal diameter of the ring is dimensioned so as to create an intracorneal pinhole and improve the near and intermediate vision of the non-dominant eye while only slightly altering the distance vision of that eye. The pinhole dye ring in the cornea of the presbyopic eyes enhances the depth of field, thereby allowing improved presbyopic performance without the need for corrective lenses.

Abstract: An ophthalmic surgery system and method for treating presbyopia by performing ablative photodecomposition of the corneal surface. The offset image of a variable aperture, such as a variable width slit and variable diameter iris diaphragm, is scanned in a preselected pattern to perform ablative sculpting of predetermined portions of a corneal surface. The scanning is performed to ablate an optical zone sized to match the patient pupil with a peripheral transition zone outside the pupil. The shape of the ablated optical zone is different from the shape of the final optical correction on the anterior surface of the cornea. The optical zone corrects for near-vision centrally and far-vision peripherally. A movable image displacement mechanism enables radial displacement and angular rotation of the profiled beam exiting from the variable aperture.

Abstract: System and method for making incisions in eye tissue at different depths. The system and method focuses light, possibly in a pattern, at various focal points which are at various depths within the eye tissue. A segmented lens can be used to create multiple focal points simultaneously. Optimal incisions can be achieved by sequentially or simultaneously focusing lights at different depths, creating an expanded column of plasma, and creating a beam with an elongated waist.

Abstract: A method and a device for forming cut surfaces in a transparent material, particularly in the cornea, by producing optical breakthroughs in the material by application of laser radiation focused into the material. The focal point is adjusted in three dimensions to form the cut surface by the sequential arrangement of optical perforations. The focal point is guided in such a manner that cutting is divided into at least two steps, and in at least one of the steps, the formation of the cut is carried out with a path radius that decreases in size, and in one of the steps, the cut formation is carried out with a path radius that increases in size.

Abstract: A treatment method and apparatus for surgical correction of defective-eyesight in an eye of a patient, wherein a laser device is controlled by a control device, said laser device separating corneal tissue by irradiation of laser radiation to isolate a volume located within a cornea, wherein the control device controls the laser device to focus the laser radiation, by providing target points located within the cornea, into the cornea, wherein the control device, when providing the target points, allows for focus position errors which lead to a deviation between the predetermined position and the actual position of the target points when focusing the laser radiation, by pre-offsets depending on the positions of the respective target points to compensate for said focus position errors.

Abstract: An ophthalmic surgical laser system includes a laser engine, to generate a laser beam, a first Z scanner, to receive the generated laser beam, and to scan a focal spot of the laser system over a first Z interval along an optical axis of the laser system an XY scanner, to receive the laser beam output by the first Z scanner, and to scan the focal spot of the laser system in a direction essentially transverse to the optical axis of the laser system, and a second Z scanner, to receive the scanned laser beam from the XY scanner, and to scan the focal spot of the laser system over a second Z interval along the optical axis of the laser system.

Abstract: A planning unit produces control data for a treatment device for eye surgery which produces at least one cutting surface in a cornea of the eye using a laser unit. The planning unit includes a calculation module for establishing a cornea cutting surface. The calculation module is configured to establish the cornea cutting surface based on data of a refraction correction, to produce a control data set for actuating the laser unit for the cornea cutting surface, and to determine the cornea cutting surface in such a way that the cornea cutting surface contributes to fixing an implant in an interlocking manner.

Abstract: An apparatus and a method for refractive surgery, in particular LASIK, make provision whereby the apex of the cornea is taken as a basis, as the ablation center, for the refractive procedure. For this purpose, the dependence of the position of the apex on properties of the pupil is determined in the case of the eye to be treated and, from this dependence, measured properties of the pupil are used to calculate the position of the ablation center during the refractive surgery.

Abstract: A treatment apparatus for surgical correction of presbyopia or defective eyesight in an eye of a patient. The treatment apparatus includes a laser device configured to treat lens tissue of the eye by irradiation of pulsed laser radiation with the laser radiation being focused on target points arranged in a pattern within the lens. An interface supplies measurement data on parameters of the eye and/or defective-eyesight data on the eyesight defect to be corrected in the eye, and defines a volume located within the lens using the supplied measurement data and defective-eyesight data, the volume being defined so as to achieve the desired correction of presbyopia or defective eyesight when removed.

Abstract: A system and method for increasing the amplitude of accommodation and/or changing the refractive power of lens material of a natural crystalline lens is provided. Generally, there is provided methods and systems for delivering a laser beam to a lens of an eye in a plurality of patterns results in the increased accommodative amplitude and/or refractive power of the lens. There is further provided a system and method of treating presbyopia by increasing both the flexibility of the human lens and the depth of field of the eye.

Abstract: System and method of intrastromal refractive correction. The system includes a laser source operable to produce a pulsed beam, a scanner operable to direct the pulsed beam at the eye, and a controller coupled to the laser source and the scanner. The controller determines an intrastromal incision pattern based on a refractive condition of an eye, and directs the scanner to intrastromally incise the pattern in an applanated cornea with the pulsed beam. Following de-applanation, the cornea is reshaped in response to the intrastromal incision pattern to correct the refractive condition.