Abstract: A method for treating an oral cavity malady of a patient, comprising: applying a spot of a laser beam to a target area around the oral cavity, said laser beam having a wavelength of about 800 to 840 nm and a power of between 1000 and 4000 mW, and wherein said spot has a spot size of about 1 to about 10 mm; and moving said spot on said target area for a treatment time sufficient to deliver a dose of about 0.5 to about 30 J/cm2 to said target area.

Abstract: An apparatus for treating tissue includes a first energy application device to direct energy at tissue of a patient to cause at least one channel to be formed and a controller to control application of energy from the first energy application device to form the at least one channel. The at least one channel may be in the shape of a spiral-like shape or may be in a flower-like shape. Mechanisms are provided to help open channels formed in the human skin structure. A second energy application source may be used to maintain the channel open after formation. The controller may cause the first energy application device to form a plurality of channels of varying depth, width and distribution over the human skin surface. The apparatus to control the application of energy may be operated using a foot-activated pedal.

Abstract: “TRI-DIODE FOR LASER THERAPY AND TRI-DIODE-BASED EQUIPMENT FOR USE IN LASER THERAPY”, this invention patent application proposes a tri-diode used to generate a particular type of laser that can be used to treat all types of cellular lesions, both in humans and in other animals. The invention can be applied to any age of patient and any lesion condition. The tri-diode proposed generates a laser from a combination of three specific molecules, namely: zinc, phosphorus or phosphate and aluminum; it is used to encourage cell regeneration, having a useable power of between 1.2 W and 1.5 W in each diode and a total power of between 3.6 W and 4.5 W, with a wavelength of between 780 and 808 nm; the zinc, phosphorus or phosphate and aluminum molecules can be combined in up to 26 mixtures.

Abstract: A portable vein viewer apparatus may be battery powered and hand-held to reveal patient vasculature information to aid in venipuncture processes. The apparatus comprises a first laser diode emitting infrared light, and a second laser diode emitting only visible wavelengths, wherein vasculature absorbs a portion of the infrared light causing reflection of a contrasted infrared image. A pair of silicon PIN photodiodes, responsive to the contrasted infrared image, causes transmission of a corresponding signal. The signal is processed through circuitry to amplify, sum, and filter the outputted signals, and with the use of an image processing algorithm, the contrasted image is projected onto the patient's skin surface using the second laser diode. Revealed information may comprise vein location, depth, diameter, and degree of certainty of vein locations. Projection of vein images may be a positive or a negative image. Venipuncture needles may be coated to provide visibility in projected images.

Abstract: A noninvasive physiological sensor for measuring one or more physiological parameters of a medical patient can include a bump interposed between a light source and a photodetector. The bump can be placed in contact with body tissue of a patient and thereby reduce a thickness of the body tissue. As a result, an optical pathlength between the light source and the photodetector can be reduced. In addition, the sensor can include a heat sink that can direct heat away from the light source. Moreover, the sensor can include shielding in the optical path between the light source and the photodetector. The shielding can reduce noise received by the photodetector.

Abstract: Apparatuses and methods are disclosed for applying laser energy having desired pulse characteristics, including a sufficiently short duration and/or a sufficiently high energy for the photomechanical treatment of skin pigmentations and pigmented lesions, both naturally-occurring (e.g., birthmarks), as well as artificial (e.g., tattoos). The laser energy may be generated with an apparatus having a resonator with the capability of switching between a modelocked pulse operating mode and an amplification operating mode. The operating modes are carried out through the application of a time-dependent bias voltage, having waveforms as described herein, to an electro-optical device (e.g., a Pockels cell) positioned along the optical axis of the resonator.

Abstract: A catheter configured to deliver therapeutic energy to a tissue can include can include an elongate shaft extending along a shaft longitudinal axis and comprising a shaft proximal end and a shaft distal end. The catheter can include a flexible tip assembly comprising a tip assembly outer surface, wherein the flexible tip assembly is connected to the shaft distal end and is configured to deliver therapeutic energy to the tissue, and wherein the flexible tip assembly further includes. The flexible tip assembly can include an insulative layer comprising an insulative layer outer surface, wherein the insulative layer is disposed on the tip assembly outer surface and a mapping electrode disposed on the insulative layer outer surface.

Abstract: In one embodiment, a personal care implement is disclosed. The personal care implement has an emitting end and an electromagnetic source for projecting electromagnetic radiation onto an area of skin to treat a skin condition. A light sensor is configured to sense an amount of ambient light present at the emitting end. A controller instructs the electromagnetic source to begin projecting only when the light sensor senses that the amount of ambient light at the emitting end is below a predefined threshold.

Abstract: Disclosed herein include embodiments of a system, a device, and a method for sorting a plurality cells of a sample. A plurality of raw images comprising pixels of complex values in a frequency space can be generated from a plurality of channels of fluorescence intensity data of fluorescence emissions of fluorophores, the fluorescence emissions being elicited by fluorescence imaging using radiofrequency-multiplexed excitation in a temporal space. Spectral unmixing can be performed on the raw images prior to a sorting decision being made.

Abstract: A catheter system for treating a treatment site within or adjacent to a vessel wall within a body of a patient includes an energy source, a balloon, and an energy guide. The energy source generates energy. The balloon includes a balloon wall that defines a balloon interior. The balloon is configured to retain a balloon fluid within the balloon interior. The balloon is selectively inflatable with the balloon fluid to expand to an inflated state, wherein when the balloon is in the inflated state the balloon wall is configured to be positioned substantially adjacent to the treatment site. The balloon further includes a balloon central axis that extends through a geometric center of the balloon when the balloon is in the inflated state. The energy guide selectively receives energy from the energy source and guides the energy from the energy source into the balloon interior. The energy guide including a guide distal end that is positioned on the balloon central axis when the balloon is in the inflated state.

Abstract: A method of body tissue ablation includes defining a target amount of ablation energy needed to create a specified lesion in tissue in a body of a patient. Contact is made between an ablation probe and the tissue. Using the ablation probe, an ablation signal is applied to the tissue, which delivers the target amount of ablation energy during a smallest time duration permitted within a defined maximum-power constraint.

Abstract: The present invention relates to a light emitting device for providing dermatological treatment. The present invention comprises a housing structure for housing a light emitting source, a fan and a duct. The light emitting source is arranged to emit light energy to external of the device and the fan is configured for directing air heated by operation of the light emitting source into the duct. The duct is arranged to direct heated air in an airstream pathway from an outlet port of a distal end of the duct and through an aperture in the housing structure where the housing structure and the duct are relatively arranged such that no part of the housing structure extends into the air stream pathway in order to minimise heat exchange from the heated air to the housing structure.

Abstract: Disclosed herein include embodiments of a system, a device, and a method for sorting a plurality cells of a sample. A plurality of raw images comprising pixels of complex values in a frequency space can be generated from a plurality of channels of fluorescence intensity data of fluorescence emissions of fluorophores, the fluorescence emissions being elicited by fluorescence imaging using radiofrequency-multiplexed excitation in a temporal space. Spectral unmixing can be performed on the raw images prior to a sorting decision being made.

Abstract: A system may include an implantable structure with a plurality of electrodes attached thereto, where the implantable structure is configured to be implanted proximate to a nerve that innervates and is proximate to an organ involved with glucose control. The system may further include a controller configured for use to control which of the plurality of electrodes are modulation electrodes and which of the plurality of electrodes are sense electrodes, a modulation energy generator configured to deliver modulation energy using one or more of the modulation electrodes, and a nerve traffic sensor configured to sense nerve traffic in the nerve using one or more of the sense electrodes. The controller may be configured to determine if the delivered modulation energy captures the nerves based on the sensed neural activity.

Abstract: An exemplary apparatus for obtaining data for at least one portion within at least one luminal or hollow sample can be provided. For example, the apparatus can include a first optical arrangement configured to transceive at least one electromagnetic radiation to and from the portion(s). The apparatus can also include a wavelength dispersive second arrangement, which can be configured to disperse the electromagnetic radiation(s). A housing can be provided with a shape of a pill, and enclosing the first and second arrangements.

Abstract: An irradiation device capable of emitting electromagnetic radiation at variable beam angles, comprises a housing assembly including a longitudinal shell, the longitudinal shell having a first end and a second end, a first end cap assembly provided at the first end of the longitudinal shell, and a second end cap assembly provided at the second end of the longitudinal shell, a radiation source provided within the longitudinal shell, a movable lens having two ends, a first end of the movable lens provided within the first end cap assembly and a second end of the movable lens provided within the second end cap assembly, and one or more translational mechanisms provided within one or more of the first end cap assembly and the second end cap assembly, wherein the one or more translational mechanisms are adapted to cause linear motion of the movable lens with respect to the radiation source.

Abstract: System (1) for treatment by photodynamic therapy comprising an illuminating member (6) which comprises: —a core (35) carrying a light emitting surface (37), and —a hollow sheath (10) adapted to receive the core (35) with the light emitting surface (37) arranged within a balloon (11), the balloon (11) comprising a wall (12) which has an inner surface delimiting an internal space, and an outer surface, the wall (12) being flexible, wherein the internal space of the balloon (11) has a variable capacity, the wall (12) of the balloon (11) being elastically extendible and the balloon (11) presenting a plurality of inflated states in each of which the internal space is filled with a volume of light diffusing solution, and wherein the system further comprises a support provided with a transfer function relating the volume of light diffusing solution of each inflated state with at least one of a corresponding distribution of light power at the outer surface of the wall (12) of the balloon (11) and a corresponding time

Abstract: A wearable for providing light therapy to a wearer includes at least one fabric panel having an inner surface that when the wearable is worn is configured to face a wearer's skin and an outer surface opposite the inner surface and at least one side-emitting optical fiber affixed to at least one of the inner surface and the outer surface. The side-emitting optical fiber is optically connectable with an optical fiber light source and configured to project light having a therapeutic wavelength toward a wearer of the wearable. With the fabric panel laid flat, the side-emitting optical fiber includes at least one looped section that bends around more than 180 degrees.

Abstract: A cannabinoid composition comprising, purified water, hemp extract having a between 30-70% cannabidiol concentration. The hemp extract being a whole plant extract derived hemp. The composition includes 200-800 mg of ajo sacha paste dissolved in the water in a final concentration of 600 mg paste per 60 ml (2 oz) finished product. The composition further includes sangre de grado is added in the standardized aqueous commercial form at a concentration of 0.5 ml per 60 ml of finished product. The composition includes an excipient chosen from the group consisting of emulsifiers, preservatives, fragrance, flavorings, a carrier oil, and combinations thereof. A method of the invention includes adding these components together to form the composition. In particular, the method includes dissolving equal amounts of 30× Ajo Sacha paste in equal weight hot purified water. Providing a botanical carrier oil and mixing hep CBD oil, commercial Sangre de Grado solution, and Ajo Sacha solution to the botanical carrier oil.

Abstract: Photobiomodulation or low level light therapy is applied to the brain using a treatment protocol that shows improvement in treating a number of disease states and injuries of the brain. A laser probe including an LED cluster is placed perpendicular to the skull at a plurality of identified treatment points on the patient's skull for durations of 1 minute with pulsed waveforms at each location. The pattern for the treatment points varies by disease or injury state being treated. The treatment period is typically on nonconsecutive days for 6 weeks (3 times per week) or 9 weeks (2 times per week) per treatment protocol. Patients with Parkinson's disease, Alzheimer's disease, balance issues, concussions, depression, strokes, and other brain diseases or injuries have shown dramatic improvement under such treatment protocols.

Abstract: This disclosure relates to methods for treatment or prevention of retinal vascular disease by photocoagulation. More specifically, this disclosure relates to an improved technique for the placement of retinal burns so as to prevent the development of hypoxia and progression of ischemia in retinal tissue, including the macula. The methods can also be employed to prevent potential ischemic tissue damage in diabetic, pre-diabetic or other patients with ischemic retinal vascular disease, or those at risk of ischemic retinal vascular disease.

Abstract: The present invention relates to an optical treatment apparatus and an operating method thereof. The present invention provides an optical treatment apparatus and an operating method thereof, the optical treatment apparatus comprising: a treatment beam generation unit for generating a treatment beam; a beam delivery unit for forming a path through which the treatment beam generated from the treatment beam generation unit travels to a treatment area located in a fundus; a monitoring unit for irradiating a detecting beam along the path through which the treatment beam travels, and detecting state information on the treatment area on the basis of speckle change information of the detecting beam scattered and reflected from the treatment area; and a control unit for controlling the driving of the treatment beam generation unit on the basis of the state information on the treatment area detected by the monitoring unit.

Abstract: A biological information detection device includes a light source, an image capturing device, and one or more arithmetic circuits. The light source projects dots formed by light onto a target including a living body. The image capturing device includes photodetector cells and generates an image signal representing an image of the target onto which the dots are projected. The one or more arithmetic circuits detect a portion corresponding to at least a part of the living body in the image by using the image signal and calculate biological information of the living body by using image signal of the portion.

Abstract: A process for safely providing retinal phototherapy includes generating first and second light beams of a different wavelength. The first and second light beams are applied to a retinal pigment epithelium (RPE) and choroid of an eye. The amount of light reflected from the eye from the first light beam and the second light beam is measured, such as using a reflectometer. A level or concentration of the melanin within the eye is calculated using the measured amount of light reflected from the eye from the first and second light beams. When the content or density of melanin in the RPE exceeds a predetermined amount, one or more treatment parameters of the retinal phototherapy is adjusted.

Abstract: The disclosed invention relates to an improved system and method for treatment of soft tissue, e.g., for treatment of a snoring condition. The system can include a laser source; a hand piece; and a device for directing radiation emitted by the laser source to a treatment area (e.g., an oral treatment area). In some cases, the handpiece can include an optical element (e.g., a lens) mounted within a replaceable cartridge and adapted to modulate a laser beam such that it is non-ablative, prior to its delivery to a treatment region. In various embodiments, the system includes a CO2 laser capable of performing treatment in a more efficient manner than conventional techniques.

Abstract: A system and method of treating target tissue in a patient's eye, which includes generating a light beam, deflecting the light beam using a scanner to form first and second treatment patterns, delivering the first treatment pattern to the target tissue to form an incision that provides access to an eye chamber of the patient's eye, and delivering the second treatment pattern to the target tissue to form a relaxation incision along or near limbus tissue or along corneal tissue anterior to the limbus tissue of the patient's eye to reduce astigmatism thereof.

Abstract: A treatment device for a scalp including a body that defines an exterior design and has one surface in which a plurality of light irradiation holes are formed, a light generation unit provided in the body and a beam splitter that dividedly refractionates light generated in the light generation unit into a plurality of lights and guides the lights toward the plurality of the light irradiation holes and a travel direction of the light generated in the light generation unit is different from a travel direction of the light passing the beam splitter.

Abstract: Harvested stem cells are activated by treating them with an amplitude modulated laser beam having a wavelength lying in the range of 405 to 980 nanometers. The frequency of the laser beam is modulated within a range of 8 to 12 MHz. Using the activated stem cells, tissue can be repaired and regenerated by preparing the unactivated stem cells, treating the unactivated stem cells with an amplitude modulated laser beam having a pre-determined frequency for obtaining activated stem cells, administering the activated stem cells into a body containing the tissue, and using a homing beam to guide the activated stem cells within the body to the location of the tissue.

Abstract: A scanning mechanism to scan a light source, such as a low-level laser, to create a desirable energy distribution on a treatment area. The light source may include multiple light beam generators, each having a different wavelength and each having a different energy distribution. The scanning mechanism can be programmable to scan in different patterns in accordance with a desired treatment.

Abstract: An apparatus includes a controller body configured to determine whether a light irradiation mode is selected and an operation is started through a user's manipulation, the controller body comprising a wireless transmission unit configured to transform an LED driving signal output according to the selected light irradiation mode into a radio signal and transmit the radio signal, and a wireless electrode probe configured to wirelessly receive the LED driving signal from the controller body by establishing wireless communication with the wireless transmission unit. The wireless electrode probe is configured to be driven by the LED driving signal received from the controller body to emit the light of a predetermined wavelength range, which increases concentration of a material for relaxing smooth muscles of a human body.

Abstract: The present invention relates to an ophthalmic treatment apparatus and a method for controlling same. The ophthalmic treatment apparatus according to the present invention comprises: an image unit for generating an image of the retina area of an eyeball in a horizontal direction with respect to the plane of the focal spot of a therapeutic beam directed by a beam delivery unit; a pattern unit for providing a grid pattern to the retina area so as to correspond to the curvature of the retina area generated by the image unit; and a control unit for controlling the operation of a beam generation unit and the beam delivery unit to radiate the therapeutic beam to the intersection points of the grid pattern on the basis of the grid pattern provided by the pattern unit.

Abstract: A hand-held laser treatment device automatically sweeps a line of laser energy across a treatment area of a patient without moving the device. Laser energy sources reside in a scan head housing, which is rotatably connected to a body housing at a housing mount. A motorized scanning mechanism in the body housing drives a pushrod connected that is to the scan head to cause the scan head to reciprocate about the housing mount axis, moving an emitted line of laser energy up and down. The scanning mechanism comprises a rotational motor, a pushrod drive cam, a guide cam and an amplitude adjustor, all coaxially aligned along a motor axis. Interposed between the pushrod drive cam and the guide cam are the pushrod and a guide bearing aligned along an axis parallel to the motor axis. The degree of sweep is adjustable to change the size of the area treated.

Abstract: A cooling element includes a frame including one or more datums. The cooling element also includes a first window including a first proximal surface and a first distal surface. The first window is sealed to the frame. The cooling element further includes a second window sealed to the frame. The second window includes a second proximal surface and a second distal surface. The second window is configured to contact a target tissue or a tissue adjacent to the target tissue via the second distal surface. The cooing element also includes a coolant chamber located between the first distal surface of the first window and the second proximal surface of the second window and configured to receive a coolant. The first window, the second window and the coolant chamber are configured to receive and electromagnetic radiation (EMR), and transmit a portion of the received EMR to the target tissue.

Abstract: In one aspect, a system for in vivo and transcranial stimulation of brain tissue of a subject may include at least one light source, a controller to control operation of the light source, a signal detecting unit and a processor configured to receive signals from the signal detecting unit, analyze the signals and generate a feedback signal to the controller to control the light source until optimal results are obtained. In one embodiment, the light source is a laser instrument and the wavelength can range from 800 to 1100 nm. In another embodiment, the irradiance of the laser instrument can range from 50 to 1000 mW/cm2.

Abstract: The present invention relates to a laser surgery apparatus for contact laser surgery and to a method of using the laser surgery apparatus. The laser surgery apparatus (1) comprises a contact laser scalpel (3) for contact laser surgery, the contact laser scalpel (4) comprising an optical fiber (4) of IR laser radiation transmissive material and terminating at an optical fiber tip (5) having an exposed core region, and support means for holding said fiber and for positioning said scalpel (3). Said fiber tip (5) is tapered and disposed at a distal end of the scalpel (3) for contacting a tissue to be cut and comprises an uncoated contact surface (6) for transmit ting laser radiation and a guiding surface that is at least partially reflective to laser radiation and provided such that laser radiation guided by said optical fiber (4) to said fiber tip (5) will be at least partially reflected by said guiding surface and emitted through said uncoated contact surface.

Abstract: A multi-function, adjustable chiropractic table comprises a body section fixed to a table frame. A cervical section is movably attached to the table frame and securable at a desired angle. The cervical section comprises a padded head support, forehead strap, and neck bolsters. The head support is slidably mounted in a tray and translatable therein using a scissors mechanism, for linear axial traction. Pivotally mounting the tray to the cervical section permits lateral traction. A four-bar linkage, including a base frame, permits raising/lowering of the table using an actuator activated by a foot triggered wave switch comprising proximity sensors. The body section comprises a chest, lumbar, and leg sections. The chest section is replaceable with a treatment nodule comprising hot and cold compresses, or a laser enhanced spinal decompression therapy apparatus comprising a laser driven by two linear actuators to emit light according to one or more treatment protocols.

Abstract: Transcorneal and fiberoptic laser delivery systems and methods for the treatment of eye diseases wherein energy is delivered by wavelengths transparent to the cornea to effect target tissues in the eye for the control of intraocular pressure in diseases such as glaucoma by delivery systems both external to and within ocular tissues. External delivery may be effected under gonioscopic control. Internal delivery may be controlled endoscopically or fiberoptically, both systems utilizing femtosecond laser energy to excise ocular tissue. The femtosecond light energy is delivered to the target tissues to be treated to effect precisely controlled photodisruption to enable portals for the outflow of aqueous fluid in the case of glaucoma in a manner which minimizes target tissue healing responses, inflammation and scarring.

Abstract: An optical module includes an optical element, a first substrate, on a first principal plane of which the optical element is mounted, a holding member disposed on a second principal plane of the first substrate, an optical fiber inserted into a through hole of the holding member, a holding substrate with an opening, a wall surface of which is in contact with an outer peripheral surface of the holding member, an interconnecting substrate connecting the first substrate and the holding substrate, a side surface substrate, an end portion of which is connected to the holding substrate and on which an electrode is disposed, and a signal cable, a distal end portion of which is bonded to the electrode of the side surface substrate.

Abstract: A biological information detection device includes a light source, an image capturing device, and one or more arithmetic circuits. The light source projects dots formed by light onto a target including a living body. The image capturing device includes photodetector cells and generates an image signal representing an image of the target onto which the dots are projected. The one or more arithmetic circuits detect a portion corresponding to at least a part of the living body in the image by using the image signal and calculate biological information of the living body by using image signal of the portion.

Abstract: A method for determining a sequence of activation of a set of brain networks by an electronic device in the course of a predetermined cognitive task. The method includes: obtaining at least one time series of data on encephalographic activities, according to a predetermined sampling value, the data on activities representing a signal captured on the cranial surface by a capture device, during the execution of the predetermined cognitive task by at least one individual, delivering a set having at least one measurements vector per sample of the time series; for each measurements vector, determining connectivity between cortical sources, the cortical sources being obtained through measurements of a measurements vector, delivering a connectivity network; and grouping connectivity networks according to a resemblance parameter delivering a set of groups of grouped connectivity networks, each representing an activity of a given brain network at a given instant.

Abstract: The present invention relates to a photo-activated modulation of smooth muscle (PAMS) technology-based skin adhesive-type low level light irradiator system using a mobile communication device. The present invention can monitor and control the charging state of a battery embedded in a skin adhesive-type low level light irradiator, which is adhered to a specific skin area of a human body using medical double-sided tape and emits and radiates visible light for a given time period, thereby inducing a bioactive substance, such as nitric oxide, to be secreted from an internal organ or tissue of the human body which is connected to the light irradiated skin area by a peripheral nerve, in real time and wirelessly using a mobile communication device.

Abstract: A cosmetic method of treating skin tissue with a laser source includes applying a plurality of short pulses of predetermined parameters to ramp up the temperature of the skin tissue to reach a desired temperature and then applying a plurality of short pulses to maintain a temperature dwell time. The predetermined parameters are selected from one or more of: pulse peak power, pulse duration, pulse repetition rate and laser wavelength.

Abstract: Embodiments of the invention provide systems and methods for treating the retina and/or other areas of a patient's eye. The procedures may involve using one or more treatment beams (e.g., lasers) to cause photocoagulation or laser coagulation to finely cauterize ocular blood vessels and/or prevent blood vessel growth to induce one or more therapeutic benefits. In other embodiments, a series of short duration light pulses (e.g., between 5-15 microseconds) may be delivered to the retinal tissue with a thermal relaxation time delay between the pulse to limit the temperature rise of the target retinal tissue and thereby limit a thermal effect to only the retinal pigment epithelial layer. Such procedures may be used to treat diabetic retinopathy, macular edema, and/or other conditions of the eye. The treatment beam may be delivered within a treatment boundary or pattern defined on the retina of the patient's eye.

Abstract: A laser therapy device includes a solid-state laser configured for a CW operation and including a pump source, and a controller configured to generate at least one first pulse of the laser in a first-pulse operation. The controller is configured to switch on the pump source to a pump power level S1 at least once during the first-pulse operation. A rise time E, after which the pump power level S1 of the pump source is attainable and starting from the time the pump source is switched on, is in a range of 50 ns to 350 ns.

Abstract: Systems, methods, and devices used to treat eyelids, meibomian glands, ducts, and surrounding tissue are described herein. In some embodiments, an eye treatment device is disclosed, which includes a scleral shield positionable proximate an inner surface of an eyelid, the scleral shield being made of, or coated with, an energy-absorbing material activated by a light energy, and an energy transducer positionable outside of the eyelid, the energy transducer configured to provide light energy at one or more wavelengths, including a first wavelength selected to heat the energy-absorbing material. Wherein, when the eyelid is positioned between the energy transducer and the scleral shield, the light energy from the energy transducer and the heated energy-absorbing material of the scleral shield conductively heats a target tissue region sufficiently to melt meibum within meibomian glands located within or adjacent to the target tissue region.

Abstract: Methods and devices are provided for activating brown adipose tissue (BAT) with light. Generally, the methods and devices can activate BAT to increase thermogenesis, e.g., increase heat production in the patient, which over time can lead to weight loss and/or improved metabolic function. In one embodiment, a medical device is provided that activates BAT by using light to stimulate nerves that activate the BAT and/or to stimulate brown adipocytes directly, thereby increasing thermogenesis in the BAT and inducing weight loss and/or improved metabolic function through energy expenditure. The light can be configured to directly or indirectly stimulate the nerves and/or the brown adipocytes. The light can be configured to indirectly stimulate the nerves and/or the brown adipocytes by activating a light activatable medium administered to a patient and configured to respond to the light to cause activation of the brown adipose tissue.

Abstract: A phototherapy device with pain location input phototherapy device for relieving nociceptive pain of a body part of a user by illumination of at least a part of the body part. A controllable light source system (LS1, LS2, LS3) comprises at least one light source arranged on a patch structure (PS) so as to allow phototherapeutic illumination of a body part. A user interface (U_I), e.g. a touch panel (TP), is arranged to receive an input from the user regarding a spatial position on the body where the user feels pain. A control system (CS) is arranged to control the controllable light source system (LS1, LS2, LS3) in accordance with said input from the user, e.g. to spatially intensify illumination at the position where the user indicates a sensation of pain. E.g. the device may be wirelessly controlled from the a smart phone, where a map of the body can be displayed, and where the user indicates on this map where he/she feels pain.

Abstract: A system and method for using a sonic wave to influence material in a target structure requires using a confined plasma antenna to generate an electromagnetic carrier wave, ?. The confined plasma antenna also pulses the carrier wave at a sonic frequency, f, to create a sonic wave. In detail, pulsing the carrier wave results in a sequential plurality of solitons which are separated from each other by a periodicity ?, wherein ?<<?. For the present invention, f is selected to resonate with a material (e.g. a cellular structure) in a target structure (e.g. a patient).

Abstract: A process for performing retinal phototherapy or photostimulation includes generating a laser light that creates a therapeutic effect to retinal and/or foveal tissues exposed to the laser light without destroying or permanently damaging the retinal or foveal tissue. The laser light is applied to a first treatment area of the retina. After a predetermined interval of time, within a single treatment session, the laser light is reapplied to the first treatment area of the retina. During the interval of time between the laser light applications to the first treatment area, the laser light is applied to one or more additional areas of the retina that is spaced apart from the first treatment area and one another. The laser light is repeatedly applied to each of the areas to be treated until a predetermined number of laser light applications to each area to be treated has been achieved.

Abstract: Systems and methods that could reduce the potential for side effects while delivering a reduced amount of light energy and non-light energy to a patient while providing a desired therapeutic effect that might otherwise only be achievable with a higher dose of either the light energy or non-light energy administered alone are disclosed. In certain embodiments, disclosed is a system and method for treating a patient, by administering a combination of light therapy from a light energy source in addition to one, two, or more other non-light energy modalities to a target region of a patient for a synergistic therapeutic effect.