Abstract: Peptide analogs of nociceptin/orphanin FQ, compositions thereof, and their use in treatment of disorders and dysfunctions related to activation or blocking of NOP receptors are described.
Abstract: The present invention relates to a process for industrially producing tagatose starting from galactose and provides for chemical isomerisation in presence of XAlO2 and XOH (with X=Na, K) and microbiological purification of the residual galactose.
Type:
Grant
Filed:
March 9, 2010
Date of Patent:
July 24, 2012
Assignee:
Inalco S.p.A.
Inventors:
Luana Vagnoli, Silvia Giacomelli, Marco Manoni, Giovanni Cipolletti
Abstract: The use of dimiracetam in the treatment of chronic pain is disclosed. At doses higher than those previously disclosed in relation with its cognition enhancing activity (i.e. amelioration of learning and memory), dimiracetam was able to completely revert hyperalgesia or allodynia associated with several animal models of chronic pain. Dimiracetam showed high activity in iatrogenic neuropathies associated with antiviral and chemotherapeutic drug treatments and in painful conditions caused by osteoarthritis. In addition, dimiracetam was devoid of toxicity even at doses 10-fold higher than the highest therapeutic dose. The possibility of treating such debilitating pathologies with a highly effective and essentially non-toxic compound is therefore disclosed.
Type:
Grant
Filed:
June 22, 2011
Date of Patent:
July 17, 2012
Assignee:
Neurotune AG
Inventors:
Carlo Farina, Carla Ghelardini, Paola Petrillo
Abstract: A multicomponent polyurethane/vinyl ester hybrid foam system for forming a gradient foam with soft and rigid foam regions, with a polyol component (A), a polyisocyanate component (B), and a component (C), which contains a catalyst for the polymerization of the vinyl monomer, with the polyol component (A) containing, as vinyl monomer, a mixture of vinyl esters of at least one polymerizable hydroxyvinyl ester and at least one branched, at least trifunctional, polymerizable vinyl ester, and the polyisocyanate component (B) containing a thermally activatable free radical-forming agent as catalyst for the polymerization of the vinyl monomers, with the proviso that the proportion by weight of the vinyl ester mixture is greater than the proportion by weight of the at least one polyol as well as the proportion by weight of the at least one polyisocyanate.
Abstract: A two-component polyurethane/vinyl ester hybrid foam system is formed of a polyol component (A), which contains at least one polyol, a catalyst for the reaction of the polyol with the polyisocyanate, at least one polymerizable vinyl monomer and water or a blowing agent on the basis of a compressed or liquefied gas as foam-forming agent, and a polyisocyanate component (B), which contains at least one polyisocyanate and a catalyst for the polymerization of the vinyl monomer, and is designed for use as a flame retardant material and material for filling openings, cable and pipe bushings in walls, floors and/or of buildings for the purpose of fire protection.
Abstract: An apparatus for accurately determining if a substrate is properly retained by a substrate-retaining mechanism. The apparatus includes a substrate-retaining mechanism to retain a wafer, a treatment liquid supply mechanism to supply a treatment liquid to the wafer, and a rotatable cup adapted to rotate as an integral unit with the substrate-retaining mechanism while covering the outer peripheral portion of the wafer. The substrate-retaining mechanism has a retaining member with two ends. If the first end retains a wafer, the second end is in an upper position. If the first end retains no wafer, the second end is in a lower position. A touch sensor is arranged below the second end of the retaining member so that, when the second end is in the lower position, the second end makes contact with the touch sensor.
Abstract: A photocatalytic method for the hydroxylation of alkanes involving the use of a Cytochrome P450 class of enzyme as a catalyst which is activated by exposure to a pulsed blue light emitted from a light emitting diode (LED) at 450 nm±25 nm.
Abstract: A text-independent speaker verification system utilizes mel frequency cepstral coefficients analysis in the feature extraction blocks, template modeling with vector quantization in the pattern matching blocks, an adaptive threshold and an adaptive decision verdict and is implemented in a stand-alone device using less powerful microprocessors and smaller data storage devices than used by comparable systems of the prior art.
Abstract: Apparatus and method for monitoring a body portion of a user during the use of a gymnastic machine provided with a video monitoring apparatus; this method comprising a phase of defining the body portion to be monitored, followed by a phase of visually and continuously monitoring this body portion through the video monitoring apparatus; this last phase comprising a sub-phase of synchronizing the trend over time of the value of at least one operating parameter of the video monitoring apparatus with a motion of the body portion described on the basis of given kinematic information acquired by a control unit of the gymnastic machine.
Abstract: A plasticized polymer of PLGA employing ethanol as the plasticizing agent prepared at a temperature higher than the Tg and lower than the boiling point of ethanol can be used in subcutaneous implants containing active ingredients therein.
Abstract: A bearing module for supporting a rapidly rotatable shaft of a vacuum pump includes a rolling bearing for supporting rotatably the shaft, a reservoir for a lubricant having an element forming a sliding contact with a delivery structure supported on the shaft for delivery of the lubricant in the rolling bearing under action of centrifugal forces generated during rotation of the shaft, and a radial delivery element provided on a side of the rolling bearing opposite a side of the bearing at which the delivery structure is located, for returning the lubricant to the reservoir.
Abstract: A power tool stand includes a guide carriage (4), and a tool coupling (1) for a portable power tool (3) and including a carriage coupling member (1a) provided on the guide carriage (4), having a clamping surface (5a), two hooks (7a, 7b) spaced from each other along the clamping surface (5a) with at least the first hook (7a) being displaceable along the clamping surface (1a), and connectable with a tool coupling member (1b) for the power tool (3) and having a clamping surface (5b the tool coupling member (1b) having two free-lying, arranged at least partially circumferentially, bolts (6) which can be hanged behind the two associated hooks (7a, 7b) of the carriage coupling member (1a).
Type:
Grant
Filed:
November 14, 2008
Date of Patent:
June 19, 2012
Assignee:
Hilti Aktiengesellschaft
Inventors:
John van Taack-Trakranen, Christian Sattler, Markus Jocham
Abstract: The systems and processes of the present invention includes ESP variable speed drive controllers that function in conjunction with a safety logic solver, pressure sensors, and an emergency isolation valve to perform a functional test of the complete wellhead trunkline protection system without interruption of production.
Abstract: Equipment for use in changing a catheter, preferably of the type used for drainage of the urinary tract. The urinary catheter is used as an aid in emptying the urinary bladder in conditions where this cannot be done in the normal manner. The equipment of the present invention includes a sleeve mounting unit which is mounted to an indwelling catheter, and which has a branch member formed in one piece therewith and extending at an acute angle therefrom, for reception of an elongated sleeve having a longitudinal slit. The sleeve is positioned on the branch member and then progressively advanced onto the catheter, causing the slit to become enlarged as the sleeve surrounds the upstream portion of the catheter in a yielding manner. The catheter may then be quickly removed through the sleeve and a new catheter inserted in its place.
Abstract: A lubricant-tight vane rotary vacuum pump, includes a pump stage (17) having a pump stage housing (10) with a gas inlet, compression chamber (11), and a gas outlet (51), a channel (50) connecting the compression chamber (11) with the gas outlet (51), and a groove (54) at least partially surrounding a mouth of the connecting channel (50) that opens into the gas outlet (51), so that lubricant, which is tossed out of the compression chamber, is collected in the groove (54) and re-entry of the lubricant back into the compression chamber (11) is prevented.
Abstract: The method and the apparatus object of present invention refers to a system and A method that create, save and format text documents using a device with gaze control and a system of quick positioning of the cursor. The present invention provides a faster interaction and requires a minimum effort with respect to the state of the art interfaces.
Abstract: A replaceable chuck for a percussion hand-held power tool (3) for applying axial blows to a working tool receivable in the chuck, includes a release sleeve (4) axially displaceable relative to the base body (6) against a spring-biasing force and including an inwardly located locking element (11) for formlockingly securing the chuck on a power tool spindle (15) with locking elements (12) extending through respective openings (13) formed in a base body (6) and engageable in associated recesses (14) of the power tool spindle (15), and a formlocking displacement guide (5) that provides for displacement of the release sleeve (4) relative to the base body (6) and includes, along its axial extension, a tangential section.
Abstract: Disclosed is a liquid treatment apparatus capable of effectively exhausting processing liquid atmosphere around a target object. The liquid treatment apparatus includes a container, a support part located within the container that supports the target object, a rotation driving mechanism to rotate the target object supported by the support part, a processing liquid supply mechanism to supply a processing liquid to the target object, and a rotation cup, which is located outside of the outer circumference of the target object and is rotatable together with the support part. A rotation exhaust cup is arranged above the rotation cup and is rotatable together with the rotation cup. A discharge mechanism discharges processing liquid atmosphere guided by the rotation cup and the rotation exhaust cup.
Abstract: Disclosed is a substrate cleaning method for prevent damage to a pattern formed on a substrate. The substrate cleaning method includes cleaning the substrate by striking cleaning particulates carried in a flow of dry air or inert gas against a surface of the substrate, and removing the cleaning particulates.
Abstract: A one-piece molded bruxism treatment device which in upright orientation has top and bottom parts, including: an elongated band having a generally U-shape defining a closed front end part and legs extending rearward and adapted to be positioned around the outer surfaces of a person's upper gums and teeth, and two generally planar resiliently deformable bite pads oriented generally horizontally, each extending from one of the feet of the band medially toward the other.