Abstract: Methods of isolating motile cells of interest from an animal tissue is provided. Also provided are methods of determining mRNA or protein expression of a gene in motile cells of interest from an animal tissue. Additionally, methods of determining whether a cancer in a tissue of a mammal is likely to metastasize are provided. Methods are also provided for inhibiting metastasis of a cancer in a tissue of a mammal. Further provided are methods of determining resistance of a motile cancer cell population in an animal tissue to a chemotherapeutic agent.

Abstract: A system including a reference data server that stores a first set of data used in the plurality of processes, a load balancer that reconfigures the transactional data, a first stage processing system and a second stage processing system. The first stage processing system includes one or more first processing modules that execute at least one process of a first set of the plurality of processes on the reconfigured transactional data to generate first stage processed transactional data, each of the one or more first processing modules comprising an in-memory cache that stores a second set of data used in the at least one process, and a first stage data storage system that stores the first stage processed transactional data.

Abstract: The invention relates to a catheter introducer comprising: a tube-like introducer sheath; an introducer hub having a distal section and a proximal section, wherein the distal section is joined to the proximal end of the introducer sheath and the proximal section defines a chamber; a needle extending through the introducer hub and the introducer sheath and having opposite proximal and distal ends, the distal end forming a needle tip; a needle hub attached to the proximal end of the needle; a needle safety device slidably arranged on the needle, wherein the needle safety device is retained in the chamber of the introducer hub when the needle extends through the introducer hub and the introducer sheath, and removable from the introducer hub once the needle tip is received in the needle safety device upon withdrawal of the needle from the introducer sheath.

Abstract: Disclosed are azetidine analogues of nucleosidase and nucleoside phosphorylase inhibitors, the use of these compounds as pharmaceuticals, pharmaceutical compositions containing the compounds, methods of treating certain diseases using the compounds, processes for preparing the compounds, and intermediates useful in the preparation of the compounds.

Abstract: The invention consists in the use, in a process of manufacture of GCC and PCC co-ground in water, of a co-grinding agent characterised in that: a) it is constituted by a least one homopolymer and/or at least one copolymer of acrylic acid, which is partially neutralised, of which the rate of molar neutralisation is less than 75% of the total acid functions, b) and in that it is introduced: during the stage of preparation of the aqueous suspensions of GCC and PCC, and/or during stage 2) of co-grinding, and possibly during the stage of co-grinding and another stage of concentration, and possibly during this other stage of concentration. The invention also lies in the resulting aqueous suspensions of GCC and PCC, in the dry pigments of GCC and PCC obtained, and in the use of these products in paper, paint, rubber and plastic.

Abstract: A method for automatic trading of foreign exchange currencies including the steps of: receiving first signals at an order receiver based on one or more orders for foreign exchange currency trades; sending second signals from an order configuration tool that provides for selection of a preferred execution method for each of the foreign exchange trades using an algorithm; and executing each of the foreign exchange trades based on received third signals relating to a respective determined preferred execution method.

Abstract: The invention constituting the subject matter of this application is related to the production method and process regarding any and all products created by forming the EPDM rubber including a mixture of ethylene, propylene and diene by using heat and particularly the seal of the door gasket, which is a part of the washing machines.

Abstract: The invention relates to an image sensor for electronic cameras, having a plurality of light-sensitive pixels for the generation of at least one signal proportional to exposure, wherein the pixels are coupled to a read-out circuit having at least one amplifier and configured to amplify the at least one signal of a respective pixel with different amplification factors to generate differently amplified signals for the at least one signal of a respective pixel, wherein the read-out circuit has at least one output to output at least some of the differently amplified signals as output signals.

Abstract: Provided is a fastener element for securing a curing blanket over the open upper end of a concrete form. The fastener element comprises a wire body including a central portion extending laterally for at least the distance of the width of the concrete form and a pair of attachment portions at opposite ends of the central portion. The attachment portions secure the fastener element to the outer walls of the concrete form.

Abstract: A wristband wirelessly connects to a mobile phone allowing a user to talk on the mobile phone by using the wristband. The wristband includes a transmitter/receiver, a speaker and a microphone. The transmitter/receiver wirelessly pairs with the mobile phone. When the mobile phone receives an incoming call, a signal is sent to a vibrator housed within the transmitter/receiver and causes the wristband to vibrate. To connect to the call, a user can push a button located on the wristband or stretch the speaker piece and place the speaker in between his/her fingers. To disconnect from the call, the user can push the button or alternatively, release the speaker piece from in between his/her fingers which automatically triggers the transmitter/receiver to disconnect from the call.

Abstract: A bilateral data transfer system comprising a first node, a second node, a first one-way link for unidirectional transfer of first data from the first node to the second node, and a second one-way link for unidirectional transfer of second data from the second node to the first node, wherein the unidirectional transfer of the first data across the first one-way link and the unidirectional transfer of the second data across the second one-way link are independently administered by the bilateral data transfer system. Under such bilateral data transfer system, each of the one-way data links may be subject to separately administered security restrictions and data filtering processes. Hence, it enables secure bilateral communications across different network security domains.

Abstract: The present invention relates to the use of a surface-reacted natural calcium carbonate as filler in tissue paper products, to a process to prepare tissue paper products, and to a tissue paper product featuring an improved softness, wherein said surface-reacted natural calcium carbonate is the reaction product of a natural calcium carbonate with an acid and carbon dioxide, which is formed in situ by the acid treatment and/or supplied externally.

Abstract: A container includes a bottom and a plurality of walls that form a storage cavity. A primary lid is disposed over the storage cavity. The primary lid includes a top surface that defines a dispenser portion through which items within the storage cavity may be dispensed. A dispenser lid is pivotally attached to the primary lid. The dispenser lid has a closed position in which the dispenser lid is pivoted downwards relative to the primary lid to cover the dispenser portion and an open position in which the dispenser lid is pivoted upwards relative to the primary lid to expose the dispenser portion.

Abstract: Provided are methods of determining whether a compound is an inhibitor of an S100 protein. The methods utilize a biosensor that comprises the S100 protein that has a covalently bound fluorescent dye at an amino acid residue of the S100 protein that becomes less exposed to the aqueous solution upon activation of the S100 protein, where the fluorescent dye has decreased fluorescence when exposed to the aqueous solution than when protected from exposure to the aqueous solution. Also provided are methods of treating a subject having metastatic cancer.

Abstract: A strong, high density foam glass tile having a small pore size which can be used as a facade on both exterior and interior building walls. The foam glass tile of the present invention is strong enough that it can also be used as a structural member for a building. The foam glass tiles are very strong, and have a compression strength of 6000 psi (lb./sq. in.) or greater, and more particularly of 8000 lb./sq. in. or greater, and even more particularly of 10,000 lb./sq. in. or greater, and even more particularly of 12,000 lb./sq. in. or greater, and even more particularly of 14,000 lb./sq. in. or greater. These foam glass tiles will absorb more energy from an explosion, withstand higher heat and wind loading and other mechanical forces. The tiles of the present invention may have an average pore size of 1.0 mm or less, and preferably 0.7 mm or less, and more preferably 0.6 mm or less, and even more preferably 0.5 mm or less, and even more preferably 0.4 mm or less, and even more preferably 0.3 mm or less.