Abstract: The invention relates to topical compositions containing components of plants from the Purslane family and methods for improving the aesthetic appearance of skin, particularly, preventing, ameliorating, treating and/or reducing fine lines and/or wrinkles. More particularly, the present invention relates to the use of topical compositions containing extract from the Portulaca oleracea plant to treat signs of dermatological aging, especially facial lines and deep wrinkles, and/or improve the aesthetic appearance of the skin. Preferably, the composition is applied once daily to the skin.
Abstract: The present invention describes compositions and methods for treating, preventing and improving the appearance of skin, particularly, treating, preventing, ameliorating, reducing and/or eliminating fine lines and/or wrinkles of skin, wherein the compositions include limonoid constituents which inhibit acetylcholine release at neuromuscular junctions of skeletal muscle so as to relax the muscles involved with wrinkling, folding and creasing of skin, e.g., facial movement and expression. The limonoids preferably include the plant alkaloids toosendanin and azadirachtin. The compositions, which also are used to treat hyperhidrosis, are preferably applied to the skin, or are delivered by directed means to a site in need thereof.
Type:
Grant
Filed:
December 31, 2002
Date of Patent:
March 15, 2005
Assignee:
Avon Products, Inc.
Inventors:
Michelle Zheng Lu, Robert E. Kalafsky, Michele C. Duggan
Abstract: There is provided a cosmetic composition, preferably in the form of a nail polish, comprising a primary film former, one or more high-molecular weight polyurethanes, and, optionally, one or more arylsulfonamide epoxy resins.
Abstract: A method of coloring keratinous fibers with, and coloring compositions comprising, a sulfo-containing, water-dispersible polymer having carbonyloxy linking groups, and a colorant reacted into or onto the polymer backbone.
Type:
Grant
Filed:
January 8, 1998
Date of Patent:
September 14, 1999
Assignee:
Bristol-Myers Squibb Company
Inventors:
James J. Krutak, Dante J. Rutstrom, Keith C. Brown, Mario L. Garcia
Abstract: Method of treating dry, free flowing, dust forming compositions with selected liquids to agglomerate a portion of the particles into groups of particles of sufficient size so that the treated compositions are substantially dust free and retain their free flowing properties, and the compositions produced by such treatment.
Abstract: Compositions for coloring keratinous fibers comprising a sulfo-containing, water-dispersible polymer having carbonyloxy linking groups, and a colorant reacted into or onto the polymer backbone.
Type:
Grant
Filed:
December 6, 1996
Date of Patent:
March 2, 1999
Assignee:
Bristol-Myers Squibb Company
Inventors:
Mario L. Garcia, James J. Krutak, Keith C. Brown, Dante J. Rutstrom
Abstract: A method of coloring keratinous fibers with, and coloring compositions comprising, a sulfo-containing, water-dispersible polymer having carbonyloxy linking groups, and a colorant reacted into or onto the polymer backbone.
Type:
Grant
Filed:
June 7, 1995
Date of Patent:
April 7, 1998
Assignee:
Clairol, Inc.
Inventors:
James J. Krutak, Dante J. Rutstrom, Keith C. Brown, Mario L. Garcia
Abstract: Method of treating dry, free flowing, dust forming compositions with selected liquids to agglomerate a portion of the particles into groups of particles of sufficient size so that the treated compositions are substantially dust free and retain their free flowing properties, and the compositions produced by such treatment
Abstract: A single-stage process for dyeing keratinous fibers in intense colors comprising simultaneously applying to said keratinous fibers a composition comprising iodide ions, an oxidant and an effective concentration of an oxidation dye to produce said intense colors when the pH of said composition is alkaline.
Type:
Grant
Filed:
March 13, 1995
Date of Patent:
July 30, 1996
Inventors:
Alexander C. Chan, David L. Chang, Yuh-Guo Pan
Abstract: New uses of certain substituted pyrido[1,2-a]pyrimidin-4-one anti-allergy drugs are made possible by the provision of clear, stable aqueous solutions of same. The aqueous solutions contain novel combinations of drugs and stabilizers.
Abstract: A method of producing and isolating 5,6-diacetoxyindole (DAI) in a single reaction vessel comprising the following steps:(a) preparing a first solution comprising dopa, water and a solubilizing agent selected from the group consisting of an acid having a pk.sub.a value equal to or less than 4 and a first base having a pk.sub.b value equal to or greater than 10;(b) preparing a second solution comprising an oxidant, a buffer and water;(c) mixing the first and second solutions to form a combined solution which is rendered oxygen-free and has a pH of from about 6 to about 9;(d) stirring the combined solution in an inert atmosphere until 5,6-dihydroxyindole (DHI) is substantially completely formed;(e) adding a derivatizing agent and a second base to the combined solution to form a final solution;(f) stirring the final solution until the DHI is substantially fully consumed;(g) cooling the final solution to precipitate DAI;(h) isolating the precipitated DAI.
Type:
Grant
Filed:
April 29, 1994
Date of Patent:
January 23, 1996
Assignee:
Clairol, Inc.
Inventors:
Gottfried Wenke, Yuh-Guo Pan, Mu-Ill Lim, Linas Stasaitis
Abstract: There is disclosed a synergistic composition and process for skin depigmentation with reduced irritation which does not employ a corticosteroid and which employs a substituted oxybenzene and a retinoid.
Abstract: A tamper-resistant dosage form capsule for the oral administration of therapeutic agents comprises a two-part capsule which is shrunk around a caplet so that the outer wall of the caplet is bound to the inner walls of both parts of the capsule. The caplet is placed into the capsule, and the dosage form is then subjected to relatively high humidity and temperature conditions, followed by drying the dosage form in a lower humidity environment, so that the capsule is shrunk to conform to the contours of the caplet and both parts of the capsule are bonded to the caplet.
Type:
Grant
Filed:
April 21, 1994
Date of Patent:
October 10, 1995
Assignee:
Bristol-Myers Squibb Company
Inventors:
Mahesh Patell, Gerard Frunzi, F. Henry Merkle, Thomas Tencza
Abstract: Compositions comprising chemically synthesized or biosynthetic water-soluble melanin and at least one water dispersible cationic material which, when combined with the melanin, forms a composition that is suitable for use as a temporary haircolor. A process for temporarily coloring hair using those compositions.