Patents Represented by Attorney Arthur E. Jackson
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Patent number: 7285295Abstract: Provided, among other things, is a method of treating an indication of mucosal or adjacent tissue comprising periodically applying to mucosa at or adjacent to disease affected tissue a delivery device comprising a backing layer and an adhesive reservoir comprising an effective amount of appropriate composition of plant extract(s) comprising extract of Sambucus nigra, wherein the adhesive reservoir comprises 30 to 70 polymer by weight, of which a major portion comprises polyacrylic polymer, wherein the delivery device is flexible and tissue conforming.Type: GrantFiled: November 21, 2005Date of Patent: October 23, 2007Assignee: Izun Pharmaceuticals Corp.Inventors: William Levine, Aron Saffer
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Patent number: 7019024Abstract: The invention provides a pharmaceutical for treatment of neurological and neuropsychiatric disorders comprising a compound of the formula: or a pharmaceutically acceptable salt thereof.Type: GrantFiled: January 9, 2001Date of Patent: March 28, 2006Assignee: Allelix Neuroscience Inc.Inventors: Vassil Iliya Ognyanov, Laurence A. Borden, Stanley Charles Bell, Jing Zhang
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Patent number: 6875051Abstract: Provided is an electrical distribution device having three or more lateral surfaces, wherein at least two lateral surfaces are adjacent pyramidal surfaces, wherein each such adjacent pyramidal surface comprises a directionally biased power receptacle, wherein each such adjacent pyramidal surface is adapted to direct a bulky end of a transformer fitted therein downwards or in a lateral direction; wherein for downwardly-biased pyramidal surfaces, the portion of the pyramidal surface below the power receptacle is adapted to accommodate about two inches or more of a bulky end of a transformer fitted in the power receptacle; wherein laterally-biased pyramidal surfaces are adapted so that any transformer that extends over an edge of the relevant pyramidal surface towards an adjacent pyramidal surface so extends at an angle such that a transformer of high primary bulk could still be accommodated fitted into the biased power receptacle at such adjacent pyramidal surface.Type: GrantFiled: May 27, 2003Date of Patent: April 5, 2005Assignee: Design Research and Development Corp.Inventor: Stephen J. Pizak
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Patent number: 6090600Abstract: The invention provides tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the protection against infection, particularly bacterial infections.Type: GrantFiled: December 23, 1997Date of Patent: July 18, 2000Assignee: SmithKline Beecham plcInventors: John Edward Hodgson, Elizabeth Jane Lawlor
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Patent number: 6025156Abstract: Topoisomerase III polypeptides and DNA and RNA encoding such Topoisomerase III polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such Topoisomerase III for the treatment of infection, particularly bacterial infections. Antagonists against such Topoisomerase III and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of Topoisomerase III nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding Staphylococcal Topoisomerase III and for detecting the polypeptide in a host.Type: GrantFiled: October 14, 1997Date of Patent: February 15, 2000Assignee: Smithkline Beecham CorporationInventors: Michael N. Gwynn, Howard Kallendar, Leslie M. Palmer
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Patent number: 5994111Abstract: The invention provides novel tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the protection against infection, particularly bacterial infections.Type: GrantFiled: December 23, 1997Date of Patent: November 30, 1999Assignee: SmithKline Beecham plcInventors: John Edward Hodgson, Elizabeth Jane Lawlor
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Patent number: 5977085Abstract: spsB polypeptides and DNA (RNA) encoding such spsB and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such spsB for the treatment of infection, particularly bacterial infections. Antagonists against such spsB and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of spsB nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding spsB and for detecting the polypeptide in a host.Type: GrantFiled: September 30, 1997Date of Patent: November 2, 1999Assignee: SmithKline Beecham p.l.c.Inventors: Michael T. Black, Karen M. O'Dwyer
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Patent number: 5976840Abstract: The invention provides gluS polypeptides and DNA (RNA) encoding gluS polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gluS polypeptides to screen for antibacterial compounds.Type: GrantFiled: October 31, 1997Date of Patent: November 2, 1999Assignee: SmithKline Beecham CorporationInventors: Deborah D. Jaworski, Elizabeth J. Lawlor, Min Wang
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Patent number: 5965416Abstract: The invention provides tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the protection against infection, particularly bacterial infections.Type: GrantFiled: December 23, 1997Date of Patent: October 12, 1999Assignee: SmithKline Beecham plcInventors: John Edward Hodgson, Elizabeth Jane Lawlor
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Patent number: 5962259Abstract: Novel response regulator polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polynucleotides and polypeptides for the treatment of infection, particularly bacterial infections. Antagonists against such the polypeptides of the invention and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence the nucleic acid sequences and the polypeptides of the invention in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding response regulators and for detecting the polypeptide in a host.Type: GrantFiled: December 20, 1996Date of Patent: October 5, 1999Assignee: SmithKline Beecham plcInventors: John Edward Hodgson, Nicola Gail Wallis
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Patent number: 5962303Abstract: Topoisomerase III polypeptides and DNA and RNA encoding such Topoisomerase III polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such Topoisomerase III for the treatment of infection, particularly bacterial infections. Antagonists against such Topoisomerase III and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of Topoisomerase III nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding Streptococcal Topoisomerase III and for detecting the polypeptide in a host.Type: GrantFiled: October 14, 1997Date of Patent: October 5, 1999Assignee: SmithKline Beecham CorporationInventors: Michael N. Gwynn, Howard Kallendar
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Patent number: 5958734Abstract: The invention provides gluS polypeptides and DNA (RNA) encoding gluS polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gluS polypeptides to screen for antibacterial compounds.Type: GrantFiled: April 18, 1997Date of Patent: September 28, 1999Assignees: SmithKline Beecham Corporation, SmithKline Beecham plcInventor: Elizabeth Jane Lawlor
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Patent number: 5955304Abstract: The invention provides DivIB polypeptides and DNA (RNA) encoding such DivIB, particularly those of S. aureus, and a procedure for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing such DivIB for the treatment of infection, to screen for antagonists against such DivIB, diagnostic assays for detecting disease.Type: GrantFiled: April 9, 1997Date of Patent: September 21, 1999Assignees: SmithKline Beecham Corporation, SmithKline Beecham p.l.c.Inventors: John Edward Hodgson, David John Payne, Stewart Campbell Pearson
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Patent number: 5952196Abstract: The invention provides proS polypeptides and DNA (RNA) encoding proS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing proS polypeptides to screen for antibacterial compounds.Type: GrantFiled: April 18, 1997Date of Patent: September 14, 1999Assignee: SmithKline Beecham plcInventor: Elizabeth Jane Lawlor
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Patent number: 5948657Abstract: The invention provides tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the protection against infection, particularly baterial infections.Type: GrantFiled: September 16, 1997Date of Patent: September 7, 1999Assignee: SmithKline Beecham plcInventors: John Edward Hodgson, Elizabeth Jane Lawlor
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Patent number: 5939298Abstract: The invention provides pheS polypeptides and DNA (RNA) encoding pheS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pheS polypeptides to screen for antibacterial compounds.Type: GrantFiled: July 23, 1997Date of Patent: August 17, 1999Assignee: SmithKline Beecham CorporationInventors: James R Brown, Elizabeth J Lawlor, Raymond W Reichard
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Patent number: 5935816Abstract: The invention provides lysS polypeptides and DNA (RNA) encoding lysS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing lysS polypeptides to screen for antibacterial compounds.Type: GrantFiled: July 23, 1997Date of Patent: August 10, 1999Assignee: SmithKline Beecham CorporationInventors: James R. Brown, Elizabeth J Lawlor, Raymond W Reichard
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Patent number: 5932701Abstract: The invention provides ribA polypeptides and polynucleotides encoding ribA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ribA polypeptides to screen for antibacterial compounds.Type: GrantFiled: November 25, 1997Date of Patent: August 3, 1999Assignees: SmithKline Beecham Corporation, SmithKline Beecham p.l.c.Inventors: Michael Terence Black, Jason Craig Fedon, John Edward Hodgson, David Justin Charles Knowles, Michael Arthur Lonetto, Anna Lisa Kosmatka, Richard Oakley Nicholas, Leslie Marie Palmer, Lisa Kathleen Shilling, Robert King Stodola, Richard Lloyd Warren
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Patent number: D541190Type: GrantFiled: January 20, 2005Date of Patent: April 24, 2007Assignee: Design Research & Development Corp.Inventor: Stephen J. Plzak
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Patent number: D543440Type: GrantFiled: January 20, 2005Date of Patent: May 29, 2007Assignee: Design Research & Development Corp.Inventor: Stephen J. Plzak