Patents Represented by Attorney Arthur E. Jackson

Find this attorney in the Justia Lawyer Directory

  • Seryl tRNA synthetase from Staphylococcus aureus
    Patent number: 5932461
    Abstract: The invention provides tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the protection against infection, particularly bacterial infections.
    Type: Grant
    Filed: December 23, 1997
    Date of Patent: August 3, 1999
    Assignee: SmithKline Beecham, plc
    Inventors: John Edward Hodgson, Elizabeth Jane Lawlor
  • IgA Fc binding protein
    Patent number: 5928895
    Abstract: The invention provides IgA Fc binding protein polypeptides and DNA (RNA) encoding IgA Fc binding protein polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing IgA Fc binding protein polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: September 15, 1997
    Date of Patent: July 27, 1999
    Assignee: SmithKline Beecham Corporation
    Inventor: Martin Karl Russel Burnham
  • Threonyl tRNA synthetase from Staphylococcus aureus
    Patent number: 5928920
    Abstract: The invention provides tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the protection against infection, particularly bacterial infections.
    Type: Grant
    Filed: December 23, 1997
    Date of Patent: July 27, 1999
    Assignee: SmithKline Beecham plc
    Inventors: John Edward Hodgson, Elizabeth Jane Lawlor
  • Recombinant expression of polynucleotides encoding the UDP-N-acetylmuramoylalanine:D-glutamate ligase (MurD) of Streptococcus pneumoniae
    Patent number: 5929045
    Abstract: The invention provides MurD polypeptides and DNA (RNA) encoding MurD polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing MurD polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: September 19, 1997
    Date of Patent: July 27, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: Nicola Gail Wallis, Joanna Lynn Fueyo, Michael Arthur Lonetto
  • Peptide release factor, prfC (RF-3), a GTP-Binding protein
    Patent number: 5919664
    Abstract: The invention provides prfC polypeptides and DNA (RNA) encoding prfC polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing prfC polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: May 29, 1997
    Date of Patent: July 6, 1999
    Assignee: SmithKline Beecham Corporation
    Inventor: Stewart C Pearson
  • Compounds
    Patent number: 5919904
    Abstract: The invention provides Response Regulator polypeptides and DNA (RNA) encoding Response Regulator polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Response Regulator polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: January 16, 1998
    Date of Patent: July 6, 1999
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham p.l.c.
    Inventor: Nicola Gail Wallis
  • Compounds
    Patent number: 5910572
    Abstract: The invention provides Response regulator polypeptides and DNA (RNA) encoding Response regulator polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Response regulator polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: January 16, 1998
    Date of Patent: June 8, 1999
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham p.l.c.
    Inventor: Nicola Gail Wallis
  • Topoisomerase I of streptococcus pneumoniae
    Patent number: 5910414
    Abstract: topoisomerase I polypeptides and DNA and RNA encoding such topoisomerase I polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such topoisomerase I for the treatment of infection, particularly bacterial infections. Antagonists against such topoisomerase I and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of topoisomerase I nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding streptococcal topoisomerase I and for detecting the polypeptide in a host.
    Type: Grant
    Filed: October 14, 1997
    Date of Patent: June 8, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: Michael N. Gwynn, Howard Kallender
  • Tetracycline resistance protein
    Patent number: 5891670
    Abstract: The invention provides tetracycline resistance protein polypeptides and DNA (RNA) encoding tetracycline resistance protein polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tetracycline resistance protein polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: July 23, 1997
    Date of Patent: April 6, 1999
    Assignee: Smithkline Beecham Corporation
    Inventors: Martin Karl Russel Burnham, Michael Arthur Lonetto, Patrick Vernon Warren
  • Polynucleotides encoding GTP cyclohydrolase II (ribA)
    Patent number: 5891672
    Abstract: The invention provides ribA polypeptides and polynucleotides encoding ribA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ribA polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: November 25, 1997
    Date of Patent: April 6, 1999
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham p.l.c.
    Inventors: Min Wang, Judith M Ward, Richard Lloyd Warren, Richard Oakley Nicholas, Leslie Marie Palmer, Julie M Pratt, David Justin Charles Knowles, Michael Arthur Lonetto, Jeffrey Mooney, Michael Terence Black, Martin Karl Russell Burnham, Christine Debouck, Jason Craig Fedon, John Edward Hodgson, Deborah Dee Jaworski, Raymond Winfield Reichard, Martin Rosenberg, Christopher Michael Traini, Yi Yi Zhong
  • DNA encoding the SecA1 polypeptide of Staphylococcus aureus
    Patent number: 5891678
    Abstract: The invention provides secA1 polypeptides and DNA (RNA) encoding secA1 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing secA1 polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: June 4, 1997
    Date of Patent: April 6, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: Karen M O'Dwyer, Serry Sousa, Caroline Perry, Jeff Mooney, Richard Warren
  • SpoIIIe polynucleotides
    Patent number: 5891667
    Abstract: The invention provides spoIIIE polypeptides and DNA (RNA) encoding spIIIE polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing spoIIIE polypeptide for the protection against infection, particularly bacterial infections.
    Type: Grant
    Filed: January 17, 1997
    Date of Patent: April 6, 1999
    Assignee: SmithKline Beecham, p.l.c.
    Inventors: John Edward Hodgson, Alison Frances Chalker
  • Integral membrane proteins from Streptoccus pneumoniae
    Patent number: 5888771
    Abstract: The invention provides integral membrane protein polypeptides and DNA (RNA) encoding integral membrane protein polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utlizng integral membrane protein polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: September 4, 1997
    Date of Patent: March 30, 1999
    Assignee: SmithKline Beecham Corporation
    Inventor: Richard Lloyd Warren
  • TarF
    Patent number: 5889171
    Abstract: The invention provides tarF polypeptides and DNA (RNA) encoding tarF polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tarF polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: July 18, 1997
    Date of Patent: March 30, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: Alison Frances Chalker, Stephanie Van Horn, Andrew Peter Fosberry, Michael Ovari
  • Spoiiie
    Patent number: 5888770
    Abstract: The invention provides spoIIIE polypeptides and DNA (RNA) encodig spoIIIE polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utlizng spoIIIE polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: August 26, 1997
    Date of Patent: March 30, 1999
    Assignee: Smithkline Beecham Corporation
    Inventors: Alison Frances Chalker, Maria Magdalena Zalacain Feliu, James Raymond Brown, Alexander Philip Bryant
  • PhoH
    Patent number: 5885804
    Abstract: The invention provides phoh polypeptides and DNA (RNA) encoding phoh polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing phoH polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: September 18, 1997
    Date of Patent: March 23, 1999
    Assignee: Smithkline Beecham Corporation
    Inventors: Magdalena Zalacain, James Raymond Brown
  • gbpA
    Patent number: 5885805
    Abstract: The invention provides gbpA polypeptides and DNA (RNA) encoding gbpA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gbpA polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: August 20, 1997
    Date of Patent: March 23, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: Michael Arthur Lonetto, Patrick Vernon Warren, Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Raymond Winfield Reichard, Richard Oakley Nicholas, Martin Karl Russel Burnham, Julie M Pratt, Martin Rosenberg, Judith M Ward
  • FabH
    Patent number: 5885572
    Abstract: The invention provides FabH polypeptides and DNA (RNA) encoding such FabH and a procedure for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing such FabH for the treatment of infection, particularly bacterial infections. Antagonists against such FabH and their use as a therapeutic to treat infections, particularly bacterial infections are also provided. Further provided are diagnostic assays for detecting diseases related to the presence of FabH nucleic acid sequences and the polypeptides in a host. Also provided are diagnostic assays for detecting polynucleotides encoding novel Fab family proteins and for detecting such polypeptides in a host.
    Type: Grant
    Filed: August 25, 1997
    Date of Patent: March 23, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: Daniel Robert Gentry, John Timothy Lonsdale, David John Payne, Stewart Campbell Pearson
  • Response regulator in a two component signal transduction system
    Patent number: 5882889
    Abstract: The invention provides response regulator polypeptides and DNA (RNA) encoding response regulator polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing response regulator polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: June 13, 1997
    Date of Patent: March 16, 1999
    Assignee: Smithkline Beecham Corporation
    Inventor: Nicola Gail Wallis
  • Ferrichrome transport ATP-binding protein
    Patent number: 5882891
    Abstract: The invention provides Ferrichrome transport ATP-Binding Protein polypeptides and DNA (RNA) encoding Ferrichrome transport ATP-Binding Protein polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Ferrichrome transport ATP-Binding Protein polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: July 23, 1997
    Date of Patent: March 16, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Raymond Winfield Reichard, Richard Oakly Nicholas, Martin Karl Russel Burnham, Julie M Pratt, Martin Rosenberg, Judith M Ward, Michael Arthur Lonetto, Patrick Vernon Warren