Patents Represented by Attorney Arthur E. Jackson

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  • yitJ
    Patent number: 5882897
    Abstract: The invention provides yitJ polypeptides and DNA (RNA) encoding yitJ polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing yitJ polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: August 20, 1997
    Date of Patent: March 16, 1999
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham, p.l.c.
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Raymond Winfield Reichard, Richard Oakley Nicholas, Martin Karl Russel Burnham, Julie M. Pratt, Martin Rosenberg, Judith M Ward, Michael Arthur Lonetto, Patrick Vernon Warren
  • Streptococcus pneumoniae polynucleotides which encode folyl-polyglutamate synthetase (FPGS) polypeptides
    Patent number: 5882898
    Abstract: The invention provides folC polypeptides and DNA (RNA) encoding folC polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing folC polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: September 22, 1997
    Date of Patent: March 16, 1999
    Assignees: Smithkline Beecham Corporation, Smithkline Beecham p.l.c.
    Inventors: Stewart Campbell Pearson, Rebecca Claire Greenwood
  • ASPS
    Patent number: 5882892
    Abstract: The invention provides aspS polypeptides and DNA (RNA) encoding aspS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing aspS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: July 23, 1997
    Date of Patent: March 16, 1999
    Assignee: Smithkline Beecham Corporation
    Inventors: James R Brown, Elizabeth J Lawlor, Raymond W Reichard
  • aroA
    Patent number: 5883239
    Abstract: The invention provides aroA polypeptides and DNA (RNA) encoding aroA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing aroA polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: July 18, 1997
    Date of Patent: March 16, 1999
    Assignee: Smithkline Beecham Corporation
    Inventors: James Raymond Brown, Alison Frances Chalker, David John Payne, Lisa Kathleen Shilling, Christopher Michael Traini
  • M protein
    Patent number: 5882896
    Abstract: The invention provides M Protein polypeptides and DNA (RNA) encoding M Protein polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing M Protein polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: September 15, 1997
    Date of Patent: March 16, 1999
    Assignees: Smithkline Beecham Corporation, Smithkline Beecham, p.l.c.
    Inventors: Martin Karl Russel Burnham, Stephen Dudley Holmes
  • Saliva binding protein
    Patent number: 5882871
    Abstract: The invention provides Saliva Binding Protein polypeptides and DNA (RNA) encoding Saliva Binding Protein polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Saliva Binding Protein polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: September 12, 1997
    Date of Patent: March 16, 1999
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham p.l.c.
    Inventor: Martin Karl Russel Burnham
  • Lep
    Patent number: 5882643
    Abstract: lep polypeptides and DNA (RNA) encoding such lep and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such lep for the treatment of infection, particularly bacterial infections. Antagonists against such lep and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of lep nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding leader peptidase and for detecting the polypeptide in a host.
    Type: Grant
    Filed: November 5, 1997
    Date of Patent: March 16, 1999
    Assignee: SmithKline Beecham Corporation
    Inventor: Michael Arthur Lonetto
  • Glycogen phosphorylase
    Patent number: 5882885
    Abstract: The invention provides glycogen phosphorylase polypeptides and DNA (RNA) encoding glycogen phosphorylase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing glycogen phosphorylase polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: July 17, 1997
    Date of Patent: March 16, 1999
    Assignee: Smithkline Beecham Corporation
    Inventor: Martin Karl Russel Burnham
  • GreA
    Patent number: 5866368
    Abstract: The invention provides greA polypeptides and DNA (RNA) encoding greA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing greA polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: August 22, 1997
    Date of Patent: February 2, 1999
    Assignee: Smithkline Beechman Corporation
    Inventors: Rebecca Claire Greenwood, Daniel Robert Gentry
  • RNC polynucleotides
    Patent number: 5866365
    Abstract: The invention provides rnc polypeptides and DNA (RNA) encoding rnc polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing rnc polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: June 5, 1997
    Date of Patent: February 2, 1999
    Assignee: Smithkline Beecham Corporation
    Inventors: Michael Arthur Lonetto, Martin Rosenberg
  • Amps
    Patent number: 5866369
    Abstract: The invention provides ampS polypeptides and DNA (RNA) encoding ampS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ampS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: September 18, 1997
    Date of Patent: February 2, 1999
    Assignee: Smithkline Beecham Corporation
    Inventors: Magdalena Zalacain, James Raymond Brown
  • GIDB
    Patent number: 5866367
    Abstract: The invention provides gidB polypeptides and DNA (RNA) encoding gidB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gidB polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: July 1, 1997
    Date of Patent: February 2, 1999
    Assignee: Smithkline Beecham Corporation
    Inventor: Howard Kallender
  • gidB
    Patent number: 5866366
    Abstract: The invention provides gidB polypeptides and DNA (RNA) encoding gidB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gidB polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: July 1, 1997
    Date of Patent: February 2, 1999
    Assignee: Smithkline Beecham Corporation
    Inventor: Howard Kallender
  • Aminopeptidase
    Patent number: 5866370
    Abstract: The invention provides aminopeptidase polypeptides and DNA (RNA) encoding aminopeptidase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing aminopeptidase polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: November 5, 1997
    Date of Patent: February 2, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: Sanjoy Biswas, Martin Karl Russel Burnham, Michael Arthur Lonetto, Patrick Vernon Warren, Richard Lloyd Warren
  • Lacc
    Patent number: 5861281
    Abstract: The invention provides lacC polypeptides and DNA (RNA) encoding lacC polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing lacC polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: October 30, 1997
    Date of Patent: January 19, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: James Raymond Brown, Magdalena Zalacain
  • Hiss
    Patent number: 5858720
    Abstract: The invention provides hisS polypeptides and DNA (RNA) encoding hisS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing hisS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: July 23, 1997
    Date of Patent: January 12, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: James R. Brown, Elizabeth J Lawlor, Raymond W Reichard
  • Fibronectin binding protein B compounds
    Patent number: 5858709
    Abstract: Novel fibronectin binding protein B polypeptides and DNA (RNA) encoding such novel fibronectin binding protein B and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such novel fibronectin binding protein B for the treatment of infection, particularly bacterial infections. Antagonists against such novel fibronectin binding protein B and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of novel fibronectin binding protein B nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding novel fibronectin binding protein B family and for detecting the polypeptide in a host.
    Type: Grant
    Filed: October 15, 1996
    Date of Patent: January 12, 1999
    Assignee: SmithKline Beecham p.l.c.
    Inventors: John Edward Hodgson, Martin Karl Russell Burnham
  • PCR A
    Patent number: 5858718
    Abstract: The invention provides pcrA polypeptides and DNA (RNA) encoding pcrA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pcrA polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: July 8, 1997
    Date of Patent: January 12, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Michael Arthur Lonetto, Richard O Nicholas, Robert King Stodola, David J. Holmes
  • Toothbrush with cap
    Patent number: D381809
    Type: Grant
    Filed: August 3, 1995
    Date of Patent: August 5, 1997
    Assignee: Fortune Dragon PTE Ltd.
    Inventors: Richard Weoi Meng Chee, Sharon Ah Hoon Low