Abstract: This invention relates to a novel technique for producing images of arteries that overcomes a significant limitation of conventional computed tomographic angiography (CTA). The technique is performed by the acquisition of pre-contrast computed tomography in addition to the conventional computed tomographic angiography and by the digital subtraction of the pre-contrast computed tomogram from the conventional CTA after alignment of the two images.
Type:
Grant
Filed:
August 5, 2008
Date of Patent:
August 9, 2011
Assignee:
University of Medicine and Dentistry of New Jersey
Abstract: Disclosed is a detector for monitoring a UV false positive from genuine X-ray positive of color developing radiation sensitive devices. A layer which can be scratched off and is opaque to undesired radiation but transparent to X-ray is printed on the sensor. If the sensor displays a signal (i.e., develops color), whether it is genuine or false positive can be confirmed by scratching off the opaque layer. If the signal is a genuine positive, the whole sensor will be uniformly exposed/colored including the area under the opaque layer. If it is a false positive, the area under the scratched off layer will be of lighter color than the rest of the sensor.
Abstract: Methods and kits are provided for assessing the ovarian reserve and predicting the ovarian response to fertility treatments in a female subject. The serum levels of MIS are shown to be positively correlated with the production and retrieval of mature oocytes and serve as prognostic indicators for the female response to fertility treatment. The MIS levels can be monitored prior to and during fertility treatment and are useful to adjust the timing and dosage of treatments in order to produce optimal outcome in individual patients, to avoid ovarian hyperstimulation, or to indicate cancellation of an unsuccessful treatment. MIS can also be administered to women to stimulate follicle development and to prevent depletion of ovarian reserve.
Type:
Grant
Filed:
June 29, 2007
Date of Patent:
September 23, 2008
Assignees:
University of Medicine and Dentistry of New Jersey, The General Hospital Corporation
Abstract: Methods and kits are provided for assessing the ovarian reserve and predicting the ovarian response to fertility treatments in a female subject. The serum levels of MIS are shown to be positively correlated with the production and retrieval of mature oocytes and serve as prognostic indicators for the female response to fertility treatment. The MIS levels can be monitored prior to and during fertility treatment and are useful to adjust the timing and dosage of treatments in order to produce optimal outcome in individual patients, to avoid ovarian hyperstimulation, or to indicate cancellation of an unsuccessful treatment. MIS can also be administered to women to stimulate follicle development and to prevent depletion of ovarian reserve.
Type:
Grant
Filed:
August 20, 2002
Date of Patent:
July 10, 2007
Assignees:
University of Medicine and Dentistry of New Jersey, The General Hospital Corporation
Abstract: A method is provided for the preparation of alpha-aryl-propionic acids such as ibuprofen by carbonylating the corresponding 1-arylethyl halide in an acidic aqueous medium containing a palladium catalyst. In the preparation of ibuprofen, 1-(4′-isobutylphenyl)ethyl halide is reacted with carbon monoxide in an acidic aqueous medium containing a palladium catalyst.
Abstract: The novel compounds of formula I:
wherein R, A, X1, X2, X3, Z and m have the meaning given in claim 1, and the agronomically acceptable salts or N-oxides thereof, and herbicidal compositions containing such compounds as active ingredients.
Type:
Grant
Filed:
August 25, 2000
Date of Patent:
July 16, 2002
Assignee:
BASF Aktiengesellschaft
Inventors:
Stefan Scheiblich, Thomas Maier, Helmut Siegfried Baltruschat, Thomas Hoellmueller
Abstract: The invention relates to novel 3-heterocycl-1-yluracils of formula I:
wherein R1 and R2 together with the interjacent nitrogen atom form an optionally substituted, optionally benzo-condensed 5-membered heterocyclic ring and R3 through R5 have the meaning given in claim 1. The invention also relates to a method of the production of these substances and to herbicidal compositions containing such compounds as active ingredients.
Type:
Grant
Filed:
January 31, 2000
Date of Patent:
April 23, 2002
Assignee:
BASF Aktiengesellschaft
Inventors:
Stefan Scheiblich, Trevor Newton, Peter Johannes Servaas Savio van Eijk, Isabel Waldeck
Abstract: An improved process and intermediate compounds for the preparation of 2-(N,N-disubstituted)amino-4-(perfluoroalkyl)-1,3-oxazin-6-one compounds having the structural formula I
and an improved process for the preparation of 6-(perfluoroalkyl)uracil compounds having the structural formula V
Abstract: The invention relates to a non-aqueous, emulsifiable concentrate (EC) formulation for herbicidal crop protection active compounds which consists essentially of
(a) 25 to 150 g/L of at least one fluorinated herbicidal compound,
(b) 400 to 900 g/L of one or more herbicidal alkyl phenoxyalkanoates,
(c) 10 to 100 g/L of at least one non-ionic surfactant,
(d) 10 to 100 g/L of at least one benzene sulfonate,
(e) 50 to 600 g/L of one or more solvent selected from the group consisting of aliphatic or aromatic hydrocarbons, methylated plant oils and water-miscible polar aprotic organic solvents, and
(f) optionally, up to 5 g/L of at least one defoamer,
and to the use of such a emulsifiable concentrate as a herbicide.
Abstract: There is provided a process for the recovery of essentially enantiomerically pure D-tartaric acid from aqueous and organic waste streams generated in the resolution of racemic 2-amino-2,3-dimethylbutyronitrile via the formation and isolation of a crystalline monobasic tartrate salt.
The recovered optically pure D-tartaric acid may be efficiently recycled to provide a sustainable resolution of racemic 2-amino-2,3-dimethylbutyronitrile.
Abstract: The present invention provides novel 1,4-diaryl-2-fluoro-1-buten-3-ol compounds of the structural formula I
a method for the preparation of those formula I compounds, and the use of those formula I compounds in the preparation of 1,4-diaryl-2-fluoro-1,3-butadiene compounds of formula II and 1,4-diaryl-2-fluoro-2-butene compounds of formula III
Abstract: The present invention provides a method to control parasitic and saprophagous mites on beneficial insects such as honeybees via the application of a parasiticidally or saprophagouscidally effective amount of a mitochondrial electron transport inhibitor or a pyrimidine compound of formula I.
Type:
Grant
Filed:
July 12, 1999
Date of Patent:
January 29, 2002
Assignee:
BASF Aktiengesellschaft
Inventors:
Bruce Christian Black, William R. Baumbach, Michael P. Beluch
Abstract: The present invention provides a synergistic insecticidal composition comprising as essential active ingredients a neuronal sodium channel antagonist and an arylpyrrole insecticide.
Also provided are methods for synergistic insect control and crop protection.
Type:
Grant
Filed:
March 9, 2000
Date of Patent:
January 29, 2002
Assignee:
BASF Aktiengesellschaft
Inventors:
Michael Frank Treacy, Raymond Frank Borysewicz, Paul E. Rensner
Abstract: The present invention provides herbicidal emulsifiable concentrate compositions of dinitroaniline herbicides (e.g., pendimethalin) and oxyacetamide herbicides (e.g., fluthiamid). The compositions utilize phosphoric acid as a stabilizing agent to prevent degradation of the oxyacetamide herbicide component during storage.
Abstract: The present invention provides light, extruded compositions and methods for their preparation. The light, extruded compositions comprise at least one agricultural compound; a light, extrudable, ceramic carrier; and at least one surface active agent. The present invention also provides a method for applying agricultural compounds to the water of paddy fields by localized application(s) of the light, extruded compositions to the water surface of the paddy fields.
Abstract: The novel compounds of formula I:
wherein
Het represents an optionally substituted, optionally benzofused nitrogen containing 5- or 6-membered heteroaromatic group;
R1 represents an alkyl, alkoxyalkyl or cycloalkyl group;
R2 each independently represent an alkyl or alkenyl group, and
m is 0 or an integer from 1 to 6,
and herbicidal compositions containing such compounds as active ingredients can be utilized in various agricultural methods.
Type:
Grant
Filed:
November 29, 1999
Date of Patent:
January 15, 2002
Assignee:
American Cyanamid Co.
Inventors:
Trevor Newton, Helmut Siegfried Baltruschat
Abstract: There is provided a stereospecific process for the preparation of essentially enantiomerically pure imidazolinone herbicides having the R-configuration via (R)2-amino-2,3-dimethylbutyronitrile.
Abstract: The invention relates to an insecticidal and miticidal composition which contains as active ingredients 4-bromo-2-(4-chlorophenyl)-1-(ethoxymethy)-5-(trifluoromethyl)pyrrole-3-carbonitrile in combination with one or more compounds selected from the group consisting of formamidine-type insecticidal and miticidal agents, organosulfur-type insecticidal and miticidal agents, thiocarbamate-type insecticidal and miticidal agents, phenisobromolate, pyrimidifen, milbemectin and dinitromethylheptylphenyl crotonate. The insecticidal and miticidal composition of the invention is effective against pests and mites having resistance to commercial insecticidal and miticidal agents.
Abstract: This invention relates to an insecticidal and miticidal composition which contains as active ingredients chlorfenapyr [4-bromo-2-(chlorophenyl)-1-(ethoxymethyl)-5-(trifluoromethyl)pyrrole-3-carbonitrile] in combination with asynergistic amount of at least one of a carbamate-type insecticidal compound.
Abstract: The invention relates to a process for the preparation of hetero)aryloxyheteroarylcarboxylic amide or ester of formula VI
wherein A1, A2, A3, A4, A5 Hal, X, R1, and R4 are defined within, which process comprises preparing the heteroarylcarboxylic amide or ester of formula I or a salt thereof,
from a trichoromethyl-heteroaromatic compound of formula II
and reacting the compound of formula I with an aromatic or heteroaromatic hydroxyl compound of formula VII,
R4—OH VII
optionally in the presence of a base.
Type:
Grant
Filed:
May 4, 2000
Date of Patent:
November 20, 2001
Assignee:
American Cyanamid Company
Inventors:
Marcus Knell, Monika Brink, Jan Hendrik Wevers, Willi Heinz