Abstract: This invention relates to an insecticidal and miticidal composition which contains as active ingredients chlorfenapyr in combination with one or more compounds selected from the group consisting of benzoepin, nereistoxin-type insecticidal agents and diafenthiuron.
Abstract: The present invention provides a method for the synergistic control of undesirable plants such as Ipomoea, Cyperus, Sida and Euphorbia which comprises applying to the plants or their locus a synergistically effective amount of a combination of glyphosate and an imidazolinone compound. Further provided are synergistic herbicidal compositions comprising glyphosate and an imidazolinone compound, and specifically concentrated aqueous herbicidal compositions of imidazolinyl acid salts and glyphosate salts.
Type:
Grant
Filed:
September 14, 1999
Date of Patent:
April 10, 2001
Assignee:
American Cyanamid Co.
Inventors:
Kelly Neoob DeCarvalao Castro, Timothy Malefyt, Robert M. Watkins, Wilson Mendonca, Frederick P. Salzman
Abstract: The novel optically active compounds of formula I:
(R1, Hal and L1 through L5 are defined in the specification) wherein the enantiomeric excess of the (S)-enantiomer is at least 70%., show enhanced selective fungicidal activity. The new compounds are processed with carriers, and optionally with adjuvants, to form fungicidal compositions.
Type:
Grant
Filed:
September 24, 1999
Date of Patent:
March 20, 2001
Assignee:
American Cyanamid Co.
Inventors:
Waldemar Pfrengle, Klaus-Juergen Pees, Guido Albert, Paul Carter, Annerose Rehnig, Henry Van Tuyl Cotter
Abstract: The present invention provides a method to control parasitic mites on beneficial insects, such as honeybees, via the application of a parasiticidally effective amount of tebufenpyrad.
Type:
Grant
Filed:
July 12, 1999
Date of Patent:
March 20, 2001
Assignee:
American Cyanamid Company
Inventors:
Bruce Christian Black, William R. Baumbach, Michael P. Beluch
Abstract:
Compounds of formula (I), wherein R1 represents a hydrogen atom or an optionally substituted alkyl, alkenyl, alkyloxiranyl, alkanoyl, alkoxycarbonyl, formyl, hydroxyalkyl, alkoxyalkyl, alkanoyloxyalkyl, hydroximinoalkyl, alkoxyiminoalkyl, hydrazonoalkyl or alkylhydrazonoalkyl group; R2 represents an alkoxy group; R3 and R4 each independently represent a hydrogen atom or an alkyl group; R5 represents an alkyl group, and R6 represents a group of formula —COOR7 or —CONR7R8, in which R7 and R8 show excellent fungicifal activity and systemicity and are thus useful in various agricultural applications.
Type:
Grant
Filed:
January 19, 2000
Date of Patent:
March 6, 2001
Assignee:
American Cyanamid Co.
Inventors:
Gerhard Hoefle, Udo Soeker, Annerose Rehnig, Gerhard Ewald Sieverding
Abstract: The present invention relates to novel dry-blended extrudable pesticidal resin composition, extruded pesticidal resin compositions and pelletized pesticidal resin compositions comprising, as the active ingredient, O,O-diethyl S-[[1,1-dimethylethyl)thio]-methyl]phosphorodithioate, O,O-diethyl S-(ethylthio-methyl)phosphorodithioate or a pesticidal chemical wherein said technical grade of said pesticidal chemical has a dermal and/or oral LD50, as measured on rats or rabbits of less than 50 mg/kg. The novel compositions of the present invention are characterized by markedly reduced mammalian toxicity and increased pesticide stability and are essentially free of dust. Further, the present invention also relates to a process for preparing the present safened pesticidal resin compositions.
Abstract: An improved process for the preparation of 6-(perfluoroalkyl)uracil compounds having the structural formula I
from urea compounds having the structural formula II
Abstract: There is provided a process for the dehalogenation of a compound of formula II via the use of a transition metal catalyst and ammonium formate at atmospheric pressure.
Abstract: The invention relates to a non-aqueous, stable suspension concentrate which comprises(a) 50 to 400 g/L of one or more crop protection active compounds,(b) 50 to 700 g/L of one or more adjuvants,(c) 75 to 500 g/L of one or more organic solvents,at least one dispersant selected from the groups (d) and (e)(d) 5 to 150 g/L of one or more non-ionic dispersants,(e) up to 150 g/L of one or more anionic dispersants, and optionally(f) up to 100 g/L of one or more thickeners, and to the pesticidal use of such a suspension.
Abstract: The present invention provides an improved process and intermediate compounds for the preparation of difluorovinylsilane insecticide and acaricidal agents of the formula I ##STR1## wherein Ar is phenyl, 1- or 2-napthyl or a 5- or 6-membered heteroaromatic ring, each of which may be optionally substituted by any combination of from one to three halogen,C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 haloalkyl, C.sub.1 -C.sub.4 alkoxy, haloalkoxy, C(O)R.sub.2 or S(O).sub.n R.sub.3 groups,R and R.sub.1 are each independently C.sub.1 -C.sub.4 alkyl or C.sub.3 -C.sub.5 cycloalkyl;Ar.sub.1 is phenoxyphenyl, phenyl, biphenyl, phenoxypyridyl, benzylpyridyl, benzylphenyl,1- or 2-napthyl or a 5- or 6-membered heteroaromatic ring, each of which may be optionally substituted by any combination of from one to five halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 haloalkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 haloalkoxy or C(O)R.sub.4 groups,n is an integer of 0, 1 or 2;R.sub.2 and R.sub.4 are each independently C.sub.
Abstract: There are provided 3-(1,2-benzisothiazol- and isoxazol-5-yl)-2,4(1H,3H)-pyrimidinedione or thione compounds of formula I and 3-(1,2-benzisothiazol- and isoxazol-5-yl)-4(3H)-pyrimidinone or thione compounds of formula II ##STR1## Further provided are compositions and methods comprising those compounds for the control of undesirable plant species.
Type:
Grant
Filed:
September 14, 1998
Date of Patent:
December 5, 2000
Assignee:
American Cyanmid Company
Inventors:
Peter John Wepplo, Mark Christopher Manfredi, Richard Anthony Rampulla, Michael Vernie Cossette, Michael Anthony Guaciaro, Gregory Jay Haley, Billy Gene Bullock, Sergio Ivan Alvarado, Keith Douglas Barnes, Gary Allen Meier, David Allen Hunt, Marianne Carlsen, Gavin David Heffernan
Abstract: An improved process for the preparation of 6-(perfluoroalkyl)uracil compounds having the structural formula I ##STR1## from 2-(N,N-disubstituted)amino-4-(perfluoroalkyl)-1,3-oxazin-6-one compounds having the structural formula II ##STR2##
Type:
Grant
Filed:
February 16, 1999
Date of Patent:
October 31, 2000
Assignee:
American Cyanamid Company
Inventors:
Richard Anthony Rampulla, Venkataraman Kameswaran, Peter John Wepplo
Abstract: A nucleotide sequence characteristic of Neisseria gonorrhoeae is disclosed. The sequence can be the basis for hybridization type, nucleic acid-based, rapid, in vitro diagnostic assays. The unique nature of the sequence makes it possible to clearly discriminate N. gonorrhoeae from other Neisseria species thus eliminating or substantially reducing the number of false positive readings. A 350 base pair N. gonorrhoeae DNA restriction fragment was cloned after subtractive hybridization to Neisseria meningitidis DNA. In further cloning experiments the sequences adjacent to the original 350 base pair fragment were determined. A portion of this sequence was shown to detect 105 of 106 N. gonorrhoeae strains and no other Neisseria species. In addition to use as detection probes, all or portions of the nucleotide sequence can be used as a ligand for the sandwich capture of N. gonorrhoeae sequences and as primers for in vitro amplification of N. gonorrhoeae sequences.
Abstract: The present invention relates to a method for making spray-dried tablettable powders with high edible oil loadings based on non-hydrolyzed gelatin. Said edible oils can be vitamin, flavor and fragrance oils.
Type:
Grant
Filed:
February 23, 1998
Date of Patent:
February 1, 2000
Assignee:
BASF Corporation
Inventors:
Friedemann Stroh, David Bower, Frederick Chaundy, Jeffrey Finnan, Thomas Soblesky
Abstract: The present invention relates to a stable, tasteless fat soluble vitamin emulsion composition which can be sprayed on foodstuffs at room temperature, particularly ready-to-eat breakfast cereal, for the purpose of vitamin fortification of said foodstuffs.
Abstract: A method is provided for purifying a crude N-acetyl-para-aminophenol (APAP) containing color bodies or their precursors, the method comprising: a) forming a hot aqueous solution of the crude APAP; and b) subsequently contacting the hot solution with an acid washed adsorbent carbon, e.g., an activated carbon, which acid washed carbon, prior to such contact, has been pretreated by contacting it with an aqueous solution of a reducing sulfite.
Type:
Grant
Filed:
March 15, 1994
Date of Patent:
November 9, 1999
Assignee:
BASF Corporation
Inventors:
Olan Stanley Fruchey, Edward G. Zey, Larry O. Wheeler
Abstract: A compound of formula I ##STR1## or a pharmaceutically acceptable salt thereof in which R.sub.1 and R.sub.2 are independently H or methyl (for example N,N-dimethyl-1-?1-(4-chlorophenyl)cyclobutyl!-3-methylbutylamine hydrochloride optionally in the form of its monohydrate) is used for improving the glucose tolerance of humans having Impaired Glucose Tolerance or Non-Insulin Dependent Diabetes Mellitus.
Abstract: This invention relates to N-hydroxy-dibenz?b,e!oxepinalkylamines, N-hydroxy-dibenz?b,e!oxepinalkanoic acid amides and related heterocyclic analogues of the formula ##STR1## where X together with the carbon atoms to which it is attached forms a benzene or thiophene ring; W and Z are independently hydrogen, halogen, loweralkyl, or trifluoromethyl; R.sup.1 is hydrogen, arylloweralkyl, loweralkoxycarbonyl, loweralkylcarbonyl, arylcarbonyl or arylloweralkylcarbonyl; R.sup.2 is loweralkyl, cycloalkyl, arylloweralkyl, loweralkoxycarbonyl, loweralkylcarbonyl, arylcarbonyl or arylloweralkylcarbonyl; m is 0 or 1 and n is an integer of 0 to 4 or the pharmaceutically acceptable salts thereof. The compounds of this invention are useful as analgesics and topical antiinflammatory agents for the treatment of various dermatoses and agents for the treatment of conditions where accumulation of cyclooxygenase and/or lipoxygenase metabolites is a causative factor.
Type:
Grant
Filed:
February 27, 1998
Date of Patent:
June 29, 1999
Assignee:
Hoechst Marion Roussel, Inc.
Inventors:
Richard C. Allen, Grover C. Helsley, R. Richard L. Hamer, Brian S. Freed, John I. White, Lawrence L. Martin
Abstract: This invention relates to N-hydroxy-dibenz?b,e!oxepinalkylamines, N-hydroxy-dibenz?b,e!oxepinalkanoic acid amides and related heterocyclic analogues of the formula ##STR1## where X together with the carbon atoms to which it is attached forms a benzene or thiophene ring; W and Z are independently hydrogen, halogen, loweralkyl, or trifluoromethyl; R.sup.1 is hydrogen, arylloweralkyl, loweralkoxycarbonyl, loweralkylcarbonyl, arylcarbonyl or arylloweralkylcarbonyl; R.sup.2 is loweralkyl, cycloalkyl, arylloweralkyl, loweralkoxycarbonyl, loweralkylcarbonyl, arylcarbonyl or arylloweralkylcarbonyl; m is 0 or 1 and n is an integer of 0 to 4 or the pharmaceutically acceptable salts thereof. The compounds of this invention are useful as analgesics and topical antiinflammatory agents for the treatment of various dermatoses and agents for the treatment of conditions where accumulation of cyclooxygenase and/or lipoxygenase metabolites is a causative factor.
Type:
Grant
Filed:
March 8, 1994
Date of Patent:
November 24, 1998
Assignee:
Hoechst Marion Roussel, Inc.
Inventors:
Richard C. Allen, Grover C. Helsley, R. Richard L. Hamer, Brian S. Freed, John I. White, Lawrence L. Martin
Abstract: This application relates to compounds of the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are defined within, which compounds are useful for the treatment of memory dysfunction characterized by decreased cholinergic function, pharmaceutical compositions containing the compounds and methods for making and using the compounds.
Type:
Grant
Filed:
May 22, 1995
Date of Patent:
July 7, 1998
Assignee:
Hoechst Marion Roussel, Inc.
Inventors:
Raymond W. Kosley, Jr., Larry Davis, Veronica Taberna