Abstract: There are disclosed compounds which exhibit anti-tumor activity. These compounds are of the formula I: ##STR1## wherein R.sub.1 is hydrogen, hydroxy or methoxy, R.sub.2 is hydrogen or hydroxy, and each of R.sub.3 and R.sub.4 independently is hydrogen or methyl, with the proviso that R.sub.3 and R.sub.4 are not simultaneously hydrogen, and pharmaceutically acceptable acid addition salts thereof. Also disclosed are processes for producing and using said compounds and therapeutic compositions containing same.

Abstract: An optical printing device includes a photosensitive means having a photosensitive surface and an optical print head. The optical print head has a plurality of arrays of a plurality of light emitting devices selectively energized and an optical means to form light images from the light emitting devices on the photosensitive surface.A plurality of the light emitting device arrays are arranged in a plurality of rows, with the light emitting devices aligned in a common direction with the arrays.The optical means comprises a plurality of graded index optical fiber arrays of which the optical axes are directed perpendicularly to the aforesaid photosensitive surface.

Abstract: A precious metal filings collection box for use by jewelers or other tradesmen is disclosed which provides a pilfer-proof system for collection of precious metal filings which fall from jewelry or other articles as they are worked. The collection box is shown as being part of a jeweler's bench pan and is formed of a box-like unit having a screen mesh top through which the filings fall, but the openings of the screen are too small to permit the jeweler's hand or finger to pass therethrough. A locked bottom drawer which collects the filings is provided to prevent unauthorized removal of the precious metal filings.

Abstract: An improved safety mechanism for a firearm of either the single or double action type is disclosed in which a slot or hollow is formed in the hammer behind the firing pin. The hollow houses a freely pivotably mounted anvil safety, which in the safe position of the gun is incapable of exerting a force upon the firing pin. An anvil connector bar is upwardly moved under control of the trigger to positively urge the anvil safety to form a firm impact surface against the firing pin, by eliminating the free pivotal movement of the anvil safety.

Abstract: The present invention discloses a device for detecting a laser leak for electrically detecting a leakage of laser beam due to snapping of the laser guide which is provided for guiding the laser beam to a desired position. A wire or a conductor which is connected to a detector is provided at the circumference of an optical fiber or a coating material of the laser guide. The snapping of the wire by melting or by the variation of the resistance due to raised temperature or by short-circuit of the wire on account of a dielectric break-down of the coated material is electrically detected by the detector. Thus, leakage of the laser beam from the laser guide is strictly detected to secure the safety of an apparatus and an operator.

Abstract: A water based, viscoelastic composition for use in cosmetic formulations comprising, (a) a mixture of sodium hyalfractions having different molecular weights, (b) protein which is derived from the natural material from which the hyaluronate is obtained, and (c) water. Also disclosed are cosmetic formulations comprising about 0.05-5.0% of the above composition together with an emollient, a sugar alcohol, a neutral or anionic polysaccharide, a preservative, bacteriostatic and fungistatic substance which does not react with or degrade hyaluronic acid, and water.

Abstract: A firearm having interchangeable barrels and ammunition cylinders for changing the caliber of ammunition used therewith includes a plurality of ammunition cylinders and a plurality of barrels, each barrel being threadedly mountable on the firearm frame with each barrel including a longitudinal barrel extension for interfering with the mounting and revolution of the ammunition cylinders for ammunition having a larger caliber than that of the respective barrel, and the improvement therein includes alignment marks on the barrels and frame for alignment under the full threaded engagement of each barrel in the frame, a plurality of sight ribs with each sight rib corresponding to a different barrel, means for attaching each sight rib to its corresponding barrel at a predetermined location to enable each sight rib to its corresponding barrel at a predetermined location to enable each sight rib to be operatively oriented with the rear sight for aiming the firearm when each barrel is fully threadedly engaged in the fr

Abstract: A firearm having interchangeable barrels and ammunition cylinders for changing the caliber of ammunition used therewith includes a plurality of ammunition cylinders and a plurality of barrels, each barrel being threadedly mountable on the firearm frame width each barrel including a longitudinal barrel extension for interfering with the mounting and revolution of the ammunition cylinders for ammunition having a larger caliber than that of the respective barrel, and the improvement therein includes alignment marks on the barrels and frame for alignment under the full threaded engagement of each barrel in the frame and forward sights on each of the barrels for cooperation with a rear sight on the frame to allow aiming of the firearm when the barrel is fully engaged in the frame thereby insuring that the weapon will only be used when a barrel is fully threadedly engaged in the frame and therefore that the longitudinal extension thereof will be operative to interfere with any ammunition cylinders intended for larg

Abstract: Anthracycline glycosides of the formula I ##STR1## wherein R is hydrogen or hydroxyl and the hydrochlorides thereof, and which are useful in treating certain mammalian tumors, are prepared by condensing daunomycinone with the novel sugar, 4-O-methyl-2,3,6-trideoxy-3trifluoroacetamidoribohexopyranosyl chloride in an inert organic solvent and in the presence of a soluble silver salt and a dehydrating agent to form 3', 4' -diepi-4'-O-methyl-N-trifluoroacetyl daunorubicin, and removing the N-trifluoroacetyl group therefrom. This gives the compound wherein R is hydrogen. The former is converted to the corresponding hydroxyl compound by conventional means.