Abstract: Disclosed are methods for reducing the staining of dentifrice composition containing stannous comprising administering to a subject the dentifrice composition. The dentifrice composition is a dual phase dentifrice and is contained in physically separated compartments of a dentifrice dispenser. The first dentifrice composition comprises an effective amount of one or more linear polyphosphates having an average chain length of about 4 or more and has a total water content of up to about 20%. The second dentifrice composition comprises an effective amount of stannous ions. The molar ratio of polyphosphate anion to stannous ion is from about 0.2:1 to about 5:1 and the efficacy of the stannous ion in the dentifrice is not reduced by the polyphosphate. The dentifrice composition may alternatively be a single phase dentifrice.

Abstract: The present invention relates to a per oral, oral, or intranasal pharmaceutical mucoretentive, aqueous liquid composition comprising from about 2% to about 50%, by weight of the composition, of colloidal particles of silica, titanium dioxide, clay, and mixtures thereof and a safe and effective amount of a pharmaceutical active selected from the group consisting of analgesics, decongestants, expectorants, antitussives, antihistamines, sensory agents, gastrointestinal agents, and mixtures thereof; wherein the composition has a sedimentation volume ratio of greater than about 0.90 and wherein the triggered viscosity ratio of the composition is at least about 1.2. The present invention further relates to a method of coating the alimentary canal or nasal mucosa, in particular to a method of preventing or treating symptoms of upper respiratory tract infections or upper respiratory tract tissue irritation or damage, by administering a safe and effective amount of the above composition.

Abstract: The present invention relates to oral care chewing gum composition comprising at least a minimally effective amount of chlorite ion, wherein preferably the pH of the final composition in use is greater than 7 and level of chlorine dioxide or chlorous acid is less than about 50 ppm, preferably is essentially free of chlorine dioxide or chlorous acid. This invention further relates to a method for treating breath malodor in humans or other animals, by applying a safe and effective amount of the chlorite ion composition to the oral cavity.

Abstract: Process for the manufacture of polymers having repeating units comprising spiro orthoester groups of general formula (I), wherein A is C1-6-alkylene, C1-6-alkyleneoxycarbonyl or an oxygen-carbon bond, R1 is hydrogen or methyl, R2 is C1-6-alkyl or C1-6-alkyl substituted by C1-6-alkoxy or aryloxy, R3 and R4 independently are hydrogen or C1-6-alkyl, R5 is hydrogen or methyl, R6 is hydrogen, methyl, phenyl, carboxy, carboxy-C1-6-alkyl, carboxamido or cyano, n is an integer >1 and m is 0 or an integer ≧1, with the proviso that the molecular weight of the polymer is between 500 and 1,000,000, the polymers obtained and their use specifically in dental filling materials.

Abstract: The present invention relates to oral care compositions, including therapeutic rinses, especially mouth rinses, as well as toothpastes, gels, tooth powders, chewing gums, mouth sprays, and lozenges (including breath mints), comprising at least a minimally effective amount of chlorite ion, wherein preferably the pH of the final composition is greater than 7 and level of chlorine dioxide or chlorous acid is less than about 50 ppm, preferably is essentially free of chlorine dioxide or chlorous acid. This invention further relates to a method for treating or preventing gingivitis, plaque, periodontal disease, and/or breath malodor, and/or for the whitening of teeth, in humans or other animals, by applying a safe and effective amount of the chlorite ion composition to the oral cavity.

Abstract: The invention relates to a method for treating a denture, comprising passing the denture through the air interface of an aqueous composition comprising a polymeric coating agent, especially a silicone polymer, having a weight average molecular weight of 1,000 or greater.

Abstract: Disclosed are oral compositions comprising one or more linear polyphosphates having an average chain length of about 4 or more, sodium monofluorophosphate, a buffering agent, an abrasive polishing material containing less than 23% calcium, and one or more aqueous carriers, wherein the oral composition has a total water content of from about 5% to about 20%.

Abstract: Psyllium-containing drink mix compositions comprising acid (e.g., citric acid) and granulated, less water soluble base (e.g., calcium carbonate agglomerated with maltodextrin).

Abstract: The subject invention involves compounds having the structure: wherein the C.sub..alpha. --N.sub..beta. and C.sub.5 -C.sub.6 bonds are independently single or double bonds, R1 is selected from alkyl, aryl, and heterocycle; R2-R13 are independently selected from hydrogen and other substituents; and pharmaceutically-acceptable salts thereof. The subject invention also involves pharmaceutical compositions containing such compounds, and methods for treating or preventing diseases and disorders using such compounds.

Abstract: A system for delivering an oral care substance to the oral surface, the delivery system comprising a strip of flexible material having a sufficient flexibility to form to the contours of the oral surface. The strip of material is readily conformable to oral surfaces without permanent deformation when the delivery system is placed there against. The oral care substance is applied to the strip of material such that when the delivery system is placed on the oral surface the active contacts the surface. The oral care substance also provides adhesive attachment between the strip of material and the oral surface so as to hold the delivery system in place for a sufficient amount of time to allow the active to act upon the oral surface.

Abstract: The present invention relates to oral care compositions, including therapeutic rinses, especially mouth rinses, as well as toothpaste, gels, tooth powders, chewing gums, mouth sprays, and lozenges (including breath mints), comprising at least a minimally effective amount of chlorite wherein preferably the pH of the final composition is greater than 7 and level of chlorine dioxide or chlorous acid is less than about 50 ppm, preferably is essentially free of chlorine dioxide or chlorous acid. This invention further relates to a method for treating or preventing gingivitis, plaque, periodontal disease, and/or breath malodor, and/or for the whitening of teeth, in humans or other animals, by applying a safe and effective amount of the chlorite ion composition to the oral cavity.

Abstract: A spray-dried, granular powder comprising: (i) from about 50% to about 99% of a water-soluble carrier, (ii) from about 1% to about 50% of a hydrophobic silicone oil dispersed within the carrier, wherein the spray-dried powder has a volume average particle size in the range from about 20 .mu.m to about 500 .mu.m, the powder being prepared by spray-drying an aqueous dispersion of the silicone oil and the water-soluble carrier, characterized in that the silicone oil is present in the dispersion in the form of discrete droplets having a volume average droplet size in the range from about 0.5 .mu.m to about 20 .mu.m and that the ratio of the average spray-dried particle size to the average droplet size is at least about 2.5:1. The powder is dry, free-flowing and processable into a punched tablet or other compressed forms, yet efficiently delivers the silicone oil on subsequent dissolution in water.

Abstract: The present invention relates to silicone-containing compositions and to use thereof in various household products such as personal care products, laundry and household cleaners, bleaching compositions and the like. In particular, it relates to silicone-containing lipophilic compositions based on flavorants, perfumes, coolants or antimicrobial agents as lipophiles and which display improved residuality, impact and/or efficacy on surfaces treated therewith, for example, teeth, dentures, skin, hair, laundry, dishware, working surfaces and the like. In addition, it relates to silicone-containing bleach compositions which additionally contain bleach-sensitive ingredients such as perfumes, flavorants and the like which display improved stability.

Abstract: The present invention relates to elastic laminate structures comprising an open cell polymeric mesh integrally thermal bonded between two fabric carrier layers and methods for manufacturing such laminates.

Abstract: The present invention relates to oral care compositions, including therapeutic rinses, especially mouth rinses, as well as toothpastes, gels, tooth powders, chewing gums, mouth sprays, and lozenges (including breath mints), comprising at least a minimally effective amount of chlorite ion, wherein preferably the pH of the final composition is greater than 7 and level of chlorine dioxide or chlorous acid is less than about 50 ppm, preferably is essentially free of chlorine dioxide or chlorous acid. This invention further relates to a method for treating or preventing gingivitis, plaque, periodontal disease, and/or breath malodor, and/or for the whitening of teeth, in humans or other animals, by applying a safe and effective amount of the chlorite ion composition to the oral cavity.

Abstract: An elastic laminate structure is provided which is formed from at least one fabric layer and an open cell mesh having first and second strands. The laminate structure is formed such that the first strands are integrally bonded to the first fabric layer. The integrally bonded first strands both penetrate the first fabric layer and bond mechanically and/or chemically to the fibers of the first fabric layer. In addition, the first strands are deformed such that they are substantially flat in shape and substantially coplanar with the fabric layer. The elastic second strands have a substantially elliptical shape. The integral bonding of the first strands and the deformed shape of the first strands and the second strands provides an elastic laminate structure which can be worn about the body without irritation or other discomfort.

Abstract: This invention relates to a denture adhesive composition comprising a lower alkyl vinyl ether-maleic acid, anhydride, or salt polymer or mixtures thereof, one or more metallic salts, nonionically associated with the lower alkyl vinyl ether-maleic acid, anhydride, or salt polymer, and at least one non-adhesive self-supporting layer. This invention may also comprise other adhesive components.

Abstract: The subject invention encompasses methods for prevention and treatment of a human or lower animal subject having a gastrointestinal disorder caused or mediated by one or more intestinal helminths comprising administering to the subject bismuth and one or more antimicrobials. The subject invention also encompasses compositions comprising bismuth and one or more antimicrobials for the prevention and treatment of a human or lower animal subject having a gastrointestinal disorder caused or mediated by one or more intestinal helminths.

Abstract: Disclosed are oral compositions comprising a total flavor system and one or more aqueous carriers, wherein the oral composition is a dentifrice or a mouthrinse. The total flavor system comprises a traditional oral care flavor system and a dairy-creme component.

Abstract: This invention relates to a method of improving the stability of a bleach and lipophile composition comprising an inorganic persalt bleaching agent and a lipophile selected from the group consisting of flavorants, perfumes, coolants, antimicrobial agents, and mixtures thereof, by inclusion of an aminoalkylsilicone, having an aminoalkylsiloxane content of from about 0.1% to 2% on a repeating unit basis.