Abstract: The present invention relates to disposable elastic thermal uniaxial joint wraps having an elastic laminate structure formed from a polymeric mesh and two fabric carrier layers, and one or more heat cells, preferably one or more thermal packs comprising a plurality of individual heat cells, wherein heat is applied to specific areas of the user's body, preferably for the knee and/or elbow, preferably for pain relief. These wraps provide good conformity to user's body to deliver consistent, convenient and comfortable heat application.

Abstract: A denture cleansing composition comprising an inorganic persalt bleaching agent, an effervescence generator and an aminoalkysilicone. The composition provides improved antiplaque, cleasing and antibacterial activity together with excellent physical and in-use performance characteristics.

Abstract: An oral composition in the form of a toothpaste, powder, liquid dentifrice, mouthwash, denture cleaner, chewing gum, or candy comprising one or more oral composition components selected from abrasives, binders, humectants, surfactants, fluoride ion sources, anticalculus agents and sweetners and additionally comprising: a dimethicone copolyol selected from alkyl- and alkoxy-dimethicone copolyols having formula (I).

Abstract: The subject invention encompasses baked compositions, a therapeutically effective dose of SMOOTH TEXTURE METAMUCIL.RTM. and one or more conventional additives used in dough containing compositions. The present invention also encompasses methods for regulating bowel function and/or providing laxation and/or treating hypercholesterolemia and/or increasing fiber consumption in humans or lower animals comprising orally administering the baked compositions according to this invention.

Abstract: Disclosed are drink mix compositions comprising a therapeutically effective dose of an anion exchange resin, and xanthan gum. These compositions may also contain one or more carriers wherein the compositions are in a form mixable with a liquid to form a suspension of the anion exchange resin and xanthan gum.

Abstract: Disclosed are oral compositions and methods for reducing plaque in a human or lower animal subject comprising applying to the teeth of the subject an oral composition comprising one or more hydrophobic solvents having one or more characteristics selected from the group consisting of a hydrogen bonding parameter of less than about 7.0 and a water solubility of less than about 10%; one or more non-polymeric surfactants wherein the weight ratio of hydrophobic solvent to non-polymeric surfactant is from about 30:1 to about 1:2; and one or more aqueous carriers; wherein the oral composition is in the form of a toothpaste or mouthrinse, is non-ingestible, and has a pH of from about 5.0 to about 9.5.

Abstract: The present invention relates to a pharmaceutical composition in a unit dosage form for peroral administration in a human or lower animal, having a gastrointestinal tract comprising a small intestine and a colon with a lumen therethrough having an inlet to the colon from the small intestine, comprising:a. a safe and effective amount of a therapeutically active agent incorporated into a compressed, bi-convex tablet, with a maximum diameter of about 4 mm to about 10 mm;b. a non-pH dependent smoothing coat applied to the tablet to provide a smooth tablet surface free from edges or sharp curves; andc. an enteric polymer coating material comprising at least one inner coating layer and only one outer coating layer;wherein the therapeutically active agent is released at a point near the inlet to, or within the colon; each of the inner coating layer(s) is an enteric polymer that begins to dissolve in an aqueous media at a pH between about 5 to about 6.

Abstract: Cholestyramine, psyllium, and, optionally, polyol polyesters are administered orally to reduce blood cholesterol levels.

Abstract: A delivery system for an oral care substance includes a strip of material having a flexural stiffness less than about 50 grams/centimeter as measured on a Handle-O-Meter per ASTM test method D2923-95. The strip of material is readily conformable without permanent deformation to a shape of a tooth and its adjoining soft tissue when the delivery system is placed thereagainst. The delivery system also includes an oral care substance applied to the strip of material such that when the delivery system is placed on a surface of the tooth and its adjoining soft tissue, the substance contacts the surface providing an active onto the surface. The substance also provides adhesive attachment between the strip of material and the surface to hold the delivery system in place for a sufficient time to allow the active to act upon the surface.

Abstract: A system for delivering a tooth whitening substance to a plurality of adjacent teeth, the delivery system comprising a strip of flexible material having a sufficient flexibility to form a curved shape on a plurality of adjacent teeth and a tooth whitening substance. The strip of material is readily conformable to the teeth surfaces and to interstitial tooth spaces without permanent deformation when the delivery system is placed thereagainst. The tooth whitening substance is applied to the strip of material such that when the delivery system is placed on the surface of the teeth, the substance contacts the surface providing an active onto the surface. The substance also provides adhesive attachment between the strip of material and the surface to hold the delivery system in place for a sufficient amount of time to allow the active to act upon the surface.

Abstract: The present invention discloses oral compositions and methods for reducing plaque in a human or lower animal subject comprising applying to the teeth of the subject an oral composition comprising from about 0.5% to about 90% of a hydrophobic solvent having a hydrogen bonding parameter of less than 7.0 and a surface tension of less than 50 dynes/centimeter measured at 2% by weight of solvent in water, and from about 10% to about 99.5% of one or more aqueous carriers; wherein the oral composition is in the form of a toothpaste or mouthrinse, is non-ingestible, and has a pH of from about 5.0 to about 9.5.

Abstract: Disclosed are oral compositions and methods for reducing plaque in a human or lower animal subject comprising applying to the teeth of the subject one or more hydrophobic solvents having one or more characteristics selected from the group consisting of a hydrogen bonding parameter of less than about 7.0 and a water solubility of less than about 10%; one or more polymeric surfactants wherein the weight ratio of hydrophobic solvent to polymeric surfactant is from about 10:1 to about 1:20; and one or more aqueous carriers; wherein the oral composition is in the form of a toothpaste or mouthrinse, is non-ingestible, and has a pH of from about 5.0 to about 9.5.

Abstract: Disclosed are oral compositions comprising a nonionic surfactant and/or amphoteric surfactant, an anionic surfactant, free pyrophosphate ions or tetrasodium pyrophosphate, free fluoride ions, and one or more aqueous carriers. The compositions may also contain an alkali metal bicarbonate salt and xylitol.

Abstract: The present invention relates to a denture adhesive composition comprising a lower alkyl vinyl ether-maleic acid, anhydride, or salt polymer or mixtures thereof, and at least one non-adhesive self-supporting layer. The present invention also relates to a denture adhesive composition comprising at least one non-adhesive self-supporting layer and at least two adhesive components wherein one of the adhesive components is a lower alkyl vinyl ether-maleic acid, anhydride or salt polymer of mixtures thereof.

Abstract: A delivery system for a tooth whitening substance includes a strip of material having a flexural stiffness less than about 50 grams/centimeter as measured on a Handle-O-Meter per ASTM test method D2923-95. The strip of material is readily conformable without permanent deformation to a shape of a tooth when the delivery system is placed thereagainst. The tooth whitening substance is applied to the strip of material such that when the delivery system is placed on a surface of the tooth, the substance contacts the surface providing an active onto the surface. The substance also provides adhesive attachment between the strip of material and the surface to hold the delivery system in place for a sufficient time to allow the active to act upon the surface. A method of delivery includes pre-coating the strip of material, having the wearer apply substance to the strip of material, or having the wearer apply the substance directly to the surface before applying a strip of material.

Abstract: Disclosed is a denture adhesive composition comprising at least one non-adhesive self-supporting layer; and a partial salt of a lower alkyl vinyl ether-maleic acid copolymer wherein the partial salt comprises a cationic salt function consisting essentially of: from about 0.01% to about 10% of ferric iron cations; and from about 0.1% to about 75% of divalent and/or monovalent metal cations selected from the group consisting of zinc, calcium, magnesium, potassium, sodium, ammonium, and mixtures thereof.

Abstract: Disclosed is a denture adhesive composition comprising at least one non-adhesive self-supporting layer; and a partial salt of a lower alkyl vinyl ether-maleic acid copolymer, the partial salt copolymer comprising carboxyl groups, of which from about 50% to about 95% are neutralized by one or more metal cations; wherein the partial salt copolymer is covalently crosslinked with an organic crosslinker and wherein the molar ratio of organic crosslinker to carboxyl groups, prior to neutralization by the metal cations, is from about 0.1% to about 30%.

Abstract: Disclosed is a denture adhesive composition comprising a partial salt of a lower alkyl vinyl ether-maleic acid copolymer wherein the partial salt comprises a cationic salt function consisting essentially of: from about 0.01% to about 10% of ferric iron cations; and from about 0.1% to about 75% of divalent and/or monovalent metal cations selected from the group consisting of zinc, calcium, magnesium, potassium, sodium, ammonium, and mixtures thereof.

Abstract: The present invention relates to the use of ellagic acid for the treatment of gastrointestinal disorders by stimulating the motility of the GI tract. In particular the present invention relates to a method of treatment of constipation, heartburn, non ulcer dyspepsia, GERD, and/or esophagitis, with a pharmaceutical composition comprising a safe and effective amount of ellagic acid or pharmaceutically acceptable salts or esters thereof. Preferably the ellagic acid is administered perorally.

Abstract: The present invention relates to a pharmaceutical composition in a unit dosage form for peroral administration in a human or lower animal, having a gastrointestinal tract comprising a small intestine and a colon with a lumen therethrough having an inlet to the colon from the small intestine, comprising:a. a safe and effective amount of rapidly dissolving bisacodyl incorporated into a compressed, bi-convex tablet, with a maximum diameter of about 4 mm to about 10 mm;b. a non-pH dependent smoothing coat applied to the tablet to provide a smooth tablet surface free from edges and sharp curves; andc. an enteric polymer coating material comprising at least one inner coating layer and only one outer coating layer;wherein the rapidly dissolving bisacodyl is released at a point near the inlet to, or within the colon; each of the inner coating layer(s) is an enteric polymer that begins to dissolve in an aqueous media at a pH between about 5 to about 6.