Abstract: Disclosed herein are 10-desmethyl, 10 substituted-macrolides, their preparation, pharmaceutical compositions containing them, their use and methods of treatment using them. The 10-desmethyl macrolides are particularly useful as antibiotics.

Abstract: A system and method for dead-line conductor phase identification is provided. The system includes a receiver unit having a set of current sensors, such as current transformers. The receiver unit current sensors are coupled to conductors having a known phase in a multiphase power line. The current sensors are positioned adjacent a transformer connected to a section of the power line having an open circuit condition. A transmitter unit transmits a current signal on to a conductor at the open circuit section of the power line. The current sensors detect the current signal and the receiver unit transmits a signal to the transmitter unit identifying the phase on which the current signal was transmitted.

Abstract: A design structure embodied in a non-transitory machine readable medium used in a design process includes an apparatus for implementing speculative clock gating of digital logic circuits, including operation valid logic configured to generate, in a first pipeline stage n, a valid control signal input to a first register in a second pipeline stage n+1, the valid control signal indicative of when an operation is qualified to be performed by the second pipeline stage n+1; and speculative valid logic configured to generate, in the first pipeline stage, a speculative valid control signal used to gate a clock signal to a plurality of additional registers in the second pipeline stage, wherein the speculative valid control signal is generated using only a subset of a total number of control inputs used in generating the valid control signal, and wherein the clock signal is sent directly to the first register.

Abstract: An apparatus for providing information about a physical surrounding environment to a user includes an elongate body having first and second opposing ends and a mast, at least one sensor mountably coupled to the mast, at least one dual purpose, bi-directional haptic force feedback device including first and second haptic force feedback mechanisms and a vibrator, and a processor, which receives signals from the at least one sensor and operatively controls the at least one dual purpose, bi-directional haptic force feedback device.

Abstract: Disclosed herein are connectors for panels. In one embodiment a panel connector comprises, a connector comprising a rib-hinging geometry, wherein the rib-hinging geometry comprises living hinges, and wherein the rib-hinging geometry is capable of expanding in area. In another embodiment, a panel assembly is disclosed. The panel assembly comprises, a connector comprising a rib-hinging geometry, wherein the rib-hinging geometry comprises living hinges, a socket comprising an internal geometry, wherein the connector can be assembled to the internal geometry, and wherein the rib-hinging geometry is capable of expanding in area.

Abstract: The present invention relates to a pressure control system for maintaining the pressure differential between a reactor (1) and a feeder (2) connected thereto and provided for introducing feed into the reactor (1), characterized in that the pressure control system comprises a pressure up line (5) and a pressure release line (6), each line (5, 6) having a control valve (7, 8), both lines (5, 6) combining into one main line (3) leading to the feeder (2), wherein a filter unit (4) is provided in the main line (3); as well as to a reactor having such a pressure control system and a process utilizing a reactor with the specific pressure control system.

Abstract: Provided are a graphene sheet and a process of preparing the same. Particularly, a process of economically preparing a large-area graphene sheet having a desired thickness and a graphene sheet prepared by the process are provided.

Abstract: A method provides for welding a conductor to a conductive film which is suited for connection to a circuit board support in order to produce a printed circuit board. The depth or diameter of the conductor is preferably greater than the thickness of the conductive film. At least during the welding process, the conductive film is maintained in contact with a thermal isolation plate having a thermal conductivity less than that of the conductive film. After being placed on the circuit board support, the conductive film is partly etched away to electrically isolate electrical contact points.

Abstract: A composition comprising a carbodiimide and a polymer, wherein the carbodiimide comprises a reaction product of a) at least one of an aliphatic C4 to C20 polyisocyanate and an araliphatic C4 to C20 polyisocyanate, b) at least one of a hydroxy carboxylic acid and a hydroxy carboxylic salt, c) optionally, a further compound carrying groups able to react with isocyanate groups in an addition reaction, d) optionally, at least one other isocyanate, and the carbodiimide units being derived essentially exclusively from the isocyanate groups of component a), and the polymer comprises a reaction product of an ethylenically unsaturated carboxylic acid and at least one of a (meth)acrylate, a vinyl ester of a carboxylic acid, a vinyl aromatic compound, an ethylenically unsaturated nitrile, a vinyl halide, an aliphatic hydrocarbon, and a free-radically polymerizable monomer. Also, a method of applying the composition on and/or in a substrate.

Abstract: An array substrate includes; a thin-film transistor layer including; a gate line, a data line disposed substantially perpendicular to the gate line, and a switching element connected to the gate line and the data line, a gate insulation layer disposed on the gate line, a passivation layer disposed on the thin-film transistor layer, a shielding electrode disposed on the passivation layer, an insulation layer disposed on the shielding electrode; and a pixel electrode including a micro-slit pattern, the pixel electrode being disposed on the insulation layer and electrically connected to the switching element, wherein the shielding electrode is vertically aligned with the data line and the shielding electrode blocks an electromagnetic fringe field of the data line from effecting the pixel electrode.

Abstract: Disclosed herein is an interlock system in combination with an enclosure, including: the enclosure having a base and a door that define an interior; a rotary handle attached to the door; a disconnect switch disposed in the interior of the enclosure and including a shaft extending toward an exterior of the enclosure in a direction toward the door; a first interlocking member attached to the door and extending toward an interior of the enclosure; and a second interlocking member attached to the shaft. The handle is configured to engage the shaft when the door is closed and rotate the shaft to move the disconnect switch between an on position and an off position. The second interlocking member is configured to engage and interlock with the first interlocking member when the door is closed and the disconnect switch is in the on position.

Abstract: The crane includes a rotating part composed of a jib and of a counterjib, and a mechanism for slewing the rotating part that has at least one geared motor unit with a motor and reduction gear, and an internal main brake which is deactivated when the crane is placed out of service, in order to allow the rotating part to slew freely according to the direction of the wind. The geared motor unit also includes an internal auxiliary brake which is interposed between the motor and the reduction gear and which is activated when the crane is placed out of service in order to exert on the rotating part a braking torque which avoids uncontrolled rotation of said part when placed in weathervaning mode. The auxiliary brake can be designed to exert an adjustable braking torque.

Abstract: A method of separating a poly(arylene ether) from a solvent includes treating a poly(arylene ether)-containing solution with a devolatilizing extruder to form an extruded composition, and cooling the extruded composition with a cooling device that does not immerse the extruded composition in water. The composition may be used to isolate a poly(arylene ether) from the solvent-containing reaction mixture in which it is prepared, or to remove solvent from a multi-component poly(arylene ether)-containing thermoplastic composition.

Abstract: A telephone and a method for routing a telephone call using the telephone is provided. The telephone includes a microprocessor and a transceiver coupled to the microprocessor. The telephone further includes a voice recognition unit coupled to the microprocessor. The unit is further configured to determine when the user is speaking proximate the unit and to generate a match signal when the user is speaking. The microprocessor is configured to generate a command signal to induce the transceiver to transmit a voice mailbox routing signal to a telephone switching center upon receipt of the match signal from the unit.

Abstract: Provided are a process for economically preparing a graphene shell having a desired configuration which is applicable in various fields wherein in the process the thickness of the graphene shell can be controlled, and a graphene shell prepared by the process.

Abstract: A heat recovery system for a turbomachine system includes a heat removal system and a refrigeration system. The heat removal system is fluidly connected to at least one component of the turbomachine system. The heat removal system passes a cooling fluid through the at least one component to absorb heat. The refrigeration system is operatively connected to the heat removal system. The refrigeration system extracts the heat from the cooling fluid passing through the at least one component of the turbomachine system to produce a cooling effect.

Abstract: A heat pump system (10) includes a compressor (20), a reversing valve (30), an outdoor heat exchanger (40) and an indoor heat exchanger (50) coupled via refrigerant lines (35, 45, 55) in a conventional refrigeration circuit, a refrigerant to liquid heat exchanger (60), a refrigerant to liquid heat exchanger bypass valve (130), an outdoor heat exchanger bypass valve (230), and an indoor heat exchanger bypass valve (330). A controller (100) is provided to selectively control the respective positioning of the valves (30, 130, 230 and 330) between their respective open and closed positions so as to selectively configure the refrigerant circuit for operation in one of an air cooling only mode, an air cooling with liquid heating mode, an air heating only mode, an air heating with liquid heating mode, and a liquid heating only mode.

Abstract: Certain thiol and acylthiol compounds inhibit retrovirus growth by attacking the highly conserved zinc finger regions of essential viral proteins. These compounds, compositions containing them, and methods of using them to treat retroviral infections such as HIV are described. These compounds are also useful for preparation of vaccines comprised of inactivated retroviruses such as HIV, prevention of the transmission of such retroviruses, and detection of retroviral proteins.