Patents Represented by Attorney Carver C. Joyner

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  • Antibiotic from micromonospora purpurea JI-20
    Patent number: 3986929
    Abstract: A mutant strain of Micromonospora purpurea herein designated M. purpurea JI-20 elaborates an antibiotic complex comprising gentamicin and at least two novel antibiotic substances namely Antibiotic JI-20A and Antibiotic JI-20B. The so-produced antibiotics have an adverse effect upon the growth of gram-positive and gram-negative bacteria.
    Type: Grant
    Filed: June 9, 1975
    Date of Patent: October 19, 1976
    Assignee: Schering Corporation
    Inventors: Jan Ilavsky, Aris P. Bayan, William Charney, Hans Reimann
  • Method of isolating gentamicin C.sub.2a
    Patent number: 3984395
    Abstract: Fermentation of Micromono spora purpurea NRRL 2953 under controlled aerobic conditions produces a plurality of antibiotic substances including gentamicin C.sub.2a which has been heretofore unknown and unrecognized. A method of isolating said antibiotic is described as are the chemical and biological properties of the same.
    Type: Grant
    Filed: August 19, 1974
    Date of Patent: October 5, 1976
    Assignee: Schering Corporation
    Inventors: Peter J. L. Daniels, Joseph A. Marquez
  • Preparation of 12,13-desepoxy-12,13-dehydrorosamicin
    Patent number: 3975372
    Abstract: Described is a novel process for the preparation of 12,13-desepoxy-12,13-dehydrorosamicin by reducing rosamicin in a mineral acid solution containing Cr.sup.+.sup.+ cations. Rosamicin is an antibiotic elaborated by Micromonospora rosaria.
    Type: Grant
    Filed: February 28, 1975
    Date of Patent: August 17, 1976
    Assignee: Schering Corporation
    Inventors: Ashit K. Ganguly, Olga Sarre
  • Antibiotic G-418 and the production thereof
    Patent number: 3959254
    Abstract: A novel actinomycete herein designated Micromonospora rhodorangea elaborates a product having substantial antibacterial activity, said activity being due primarily to a novel antibiotic herein designated Antibiotic G-418. The disclosure sets forth methods for producing, isolating and using said antibiotic.
    Type: Grant
    Filed: November 8, 1973
    Date of Patent: May 25, 1976
    Assignee: Schering Corporation
    Inventors: Marvin J. Weinstein, Gerald H. Wagman, Raymond T. Testa, Joseph A. Marquez
  • Antibiotic G-52 and method for the production thereof
    Patent number: 3956068
    Abstract: A novel actinomycete herein designated Micromonospora zionensis elaborates a product having substantial antibacterial activity, said activity being due to sisomicin and the novel antibiotic substance coproduced therewith. The disclosure sets forth methods for producing, isolating and using the antibiotics.
    Type: Grant
    Filed: February 28, 1975
    Date of Patent: May 11, 1976
    Assignee: Schering Corporation
    Inventors: Marvin J. Weinstein, Gerald H. Wagman, Joseph A. Marquez
  • Actinomycin complex from micromonospora
    Patent number: 3954970
    Abstract: An antibiotic complex consisting of about 25 components herein designated antibiotic 70591 complex is produced by Micromonospora floridensis, a novel microorganism. The antibiotic complex has been classified as an actinomycin and has been found to exhibit a broad spectrum of antibacterial activity.
    Type: Grant
    Filed: May 24, 1974
    Date of Patent: May 4, 1976
    Assignee: Schering Corporation
    Inventors: Marvin J. Weinstein, Gerald H. Wagman, Joseph A. Marquez, Paul D. Watkins
  • Antibiotics and process for their manufacture
    Patent number: 3951746
    Abstract: A novel composition having antibiotic activity is produced by fermentation of the new species of microorganism, Micromonospora grisea. The antibiotic complex is composed of four components, Verdamicin I, sisomicin, Antibiotic G-418, and gentamicin A, of which Verdamicin I is a novel basic antibiotic possessing a broad antibacterial spectrum. The other components have been produced previously.
    Type: Grant
    Filed: February 18, 1975
    Date of Patent: April 20, 1976
    Assignee: Schering Corporation
    Inventors: Marvin J. Weinstein, Gerald H. Wagman, Joseph A. Marquez
  • Substituted aryl and aralkyl amides in the treatment of parkinsonism
    Patent number: 3944675
    Abstract: Amides having aromatic substituents of the formula: ##SPC1##Wherein R is an acyl radical derived from a carboxylic acid having from 3 to 20 carbon atoms, X and Y are members selected from the group consisting of hydrogen, fluoro, trifluoromethyl and hydroxy, and n is an integer selected from the group consisting of 0, 1 and 2, exhibit an effect upon the central nervous system.
    Type: Grant
    Filed: July 16, 1973
    Date of Patent: March 16, 1976
    Assignee: Schering Corporation
    Inventors: Samson Symchowicz, Hans-Peter Faro