Patents Represented by Attorney Claude J. Caroli

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  • Tri-substituted triazines
    Patent number: 4132850
    Abstract: Tri-substituted s-triazine di and triimino substituted alkyl and aryl mono and dicarboxylic acids and salts thereof useful as complement inhibitors.
    Type: Grant
    Filed: June 29, 1977
    Date of Patent: January 2, 1979
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • 2,6-Bis(1-morpholinoalkylideneamino)anthraquinones as anti-amebic agents
    Patent number: 4131676
    Abstract: 2,6-bis(-morpholinoalkylideneamino)anthraquinones that are effective against cecal and hepatic amebic infestations in warm-blooded animals are disclosed.
    Type: Grant
    Filed: February 6, 1978
    Date of Patent: December 26, 1978
    Assignee: American Cyanamid Company
    Inventors: Stanley A. Lang, Jr., Paul F. Fabio, Yang-I Lin, Keith C Murdock, Thomas L. Fields
  • Azabicyclohexanes
    Patent number: 4131611
    Abstract: Substituted 3-azabicyclo[3.1.0]hexanes, acid addition salts, method of use and method of preparation are described. The compounds have anxiolytic and analgesic activity.
    Type: Grant
    Filed: June 23, 1977
    Date of Patent: December 26, 1978
    Assignee: American Cyanamid Company
    Inventors: William J. Fanshawe, Joseph W. Epstein, Lantz S. Crawley, Corris M. Hofmann, Sidney R. Safir
  • Method of inhibiting the complement system with trisubstituted naphthalene compounds
    Patent number: 4130660
    Abstract: 1,3,5- or 1,3,6-naphthalenetriyltris(sulfonylimino)-aryl acids and salts, useful as complement inhibitors, and 1,3,5- or 1,3,6-naphthalenetriyltris(sulfonylimino)aryl acid esters which are intermediates, and the method for their preparation.
    Type: Grant
    Filed: October 28, 1977
    Date of Patent: December 19, 1978
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • Ureylenebis(anionic substituted phenylene carbonyl)imino naphthalene sulfonic acids and naphthalene carboxylic acids and their salts
    Patent number: 4129590
    Abstract: Ureylenebis(anionic substituted phenylene carbonyl)-imino naphthalene sulfonic acids and naphthalene carboxylic acids and their salts, which are useful as inhibitors of the complement system of warm-blooded animals. Naphthyl sulfonbenzamido salts, which are new intermediates for the preparation of the active ureylenes, and the process for their preparation.
    Type: Grant
    Filed: March 17, 1977
    Date of Patent: December 12, 1978
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • Ureida-phenylenebis(substituted imino)multianionic substituted dinaphthalene sulfonic acids and salts
    Patent number: 4129591
    Abstract: Ureido-phenylenebis(substituted imino)multi-anionic substituted dinaphthalene sulfonic acids and salts, which are useful as complement inhibitors.
    Type: Grant
    Filed: October 27, 1976
    Date of Patent: December 12, 1978
    Assignee: American Cyanamid Company
    Inventors: Seymour Bernstein, Robert H. Lenhard, Ransom B. Conrow
  • Hypolipemic .alpha.-aryloxy para substituted phenyl acetic acid compounds
    Patent number: 4125729
    Abstract: This invention discloses .alpha.-aryloxy para substituted phenyl acetic acid compounds that are useful in lowering sterol and triglyceride serum levels.
    Type: Grant
    Filed: February 17, 1977
    Date of Patent: November 14, 1978
    Assignee: American Cyanamid Company
    Inventors: Ronald I. Trust, Francis J. McEvoy, Jay D. Albright
  • Phenenyltris(carbonylimino) multi-anionic substituted triphenyl acids and salts
    Patent number: 4123455
    Abstract: Phenenyltris(carbonylimino) multi-anionic substituted triphenyl acids and salts useful as complement inhibitors.
    Type: Grant
    Filed: June 13, 1977
    Date of Patent: October 31, 1978
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • Dicarboxyphenyl substituted bis-sulfonylimino dibenzodithiazepine tetroxides
    Patent number: 4122088
    Abstract: Dicarboxyphenyl substituted bis-sulfonyliminodibenzodithiazepine-S,S,S',S'-tetroxide, alkali metal salts, useful as complement inhibitors, and a dicarboxyphenyl substituted bis-sulfonyliminodibenzodithiazepine,S,S,S',S'-tetroxides, 2-methoxyethyl ester that is an intermediate for the preparation of the active salts.
    Type: Grant
    Filed: July 1, 1977
    Date of Patent: October 24, 1978
    Assignee: American Cyanamid Company
    Inventors: Ransom Brown Conrow, Seymour Bernstein
  • S-Phenenyltris(sulfonylimino)tri-anionic substituted benzene dicarboxylic acids and substituted alkyl amino acids and their salts
    Patent number: 4120896
    Abstract: s-Phenenyltris(sulfonylimino)tri-anionic substituted benzene dicarboxylic acids and substituted alkyl amino acids and their salts, useful as complement inhibitors.
    Type: Grant
    Filed: June 13, 1977
    Date of Patent: October 17, 1978
    Assignee: America Cyanamid Company
    Inventors: Ransom Brown Conrow, Seymour Bernstein
  • Anionic naphthalene thioureido toluenesulfonic acids
    Patent number: 4120893
    Abstract: Anionic substituted naphthalene bis-thioureido toluenesulfonic acids, useful as complement inhibitors, and the process for their preparation.
    Type: Grant
    Filed: June 29, 1977
    Date of Patent: October 17, 1978
    Assignee: American Cyanamid Company
    Inventors: John Frank Poletto, Ransom Brown Conrow, Seymour Bernstein
  • Ureylene naphthalene sulfonic acids
    Patent number: 4120891
    Abstract: Ureylenebis-symmetrical-phenenylbiscarbonylimino-substituted phenylenecarbonylimino-tetranaphthalenepolysulfonic acid benzoic acid salts, and nitro- and amino-substituted phenylenebiscarbonylimino-substituted benzamido-phenylenedicarbonyl-dinaphthalenepolysulfonic acid benzoic acid salts which are intermediates for the preparation of the active ureides which have complement inhibiting activity.
    Type: Grant
    Filed: July 1, 1977
    Date of Patent: October 17, 1978
    Assignee: American Cyanamid Company
    Inventors: John Frank Poletto, Seymour Bernstein
  • Anionic naphthalene thioureido naphthalene sulfonic acids
    Patent number: 4120892
    Abstract: Anionic substituted naphthylenebis-thioureylene di-1,3,6-naphthalenetrisulfonic acids, useful as complement inhibitors, and the process for their preparation.
    Type: Grant
    Filed: July 5, 1977
    Date of Patent: October 17, 1978
    Assignee: American Cyanamid Company
    Inventors: John Frank Poletto, Ransom Brown Conrow, Seymour Bernstein
  • Sulfo-m-phenylenebis(sulfonylimino)diisophthalic acid salts
    Patent number: 4120894
    Abstract: Sulfo-m-phenylenebis(sulfonylimino)diisophthalic acid salts useful as complement inhibitors.
    Type: Grant
    Filed: June 13, 1977
    Date of Patent: October 17, 1978
    Assignee: American Cyanamid Company
    Inventors: Ransom Brown Conrow, Seymour Bernstein
  • S-phenenyltris (iminocarbonyl) triisophthalic acid salts
    Patent number: 4120895
    Abstract: s-Phenenyltris(iminocarbonyl)triisophthalic acid salts useful as complement inhibitors.
    Type: Grant
    Filed: June 29, 1977
    Date of Patent: October 17, 1978
    Assignee: American Cyanamid Company
    Inventors: Ransom Brown Conrow, John Frank Poletto, Seymour Bernstein
  • 2,2',2"-[S-Phenenyltris(carbonylimino) ]tris-2-deoxy-D-glucopyranose and salts thereof
    Patent number: 4120954
    Abstract: 2,2',2"-[s-Phenenyltris(carbonylimino)]tris-2-deoxy-D-glucopyranose and salts thereof, useful as complement inhibitors.
    Type: Grant
    Filed: April 4, 1977
    Date of Patent: October 17, 1978
    Assignee: American Cyanamid Company
    Inventors: Joseph Peter Joseph, Seymour Bernstein
  • Novel 2,2', 2"-[s-phenenyltris(sulfonylimino)tris]-[2-deoxy-.alpha.-D-glucopyranose] , dodecakis (H-sulfate) compounds and their salts
    Patent number: 4120953
    Abstract: Novel 2,2', 2"-[s-phenenyltris(sulfonylimino)]tris-[2-deoxy-.alpha.-D-glucopyranose], dodecakis (H-sulfate) compounds and their salts which are useful as inhibitors of the complement system of warm-blooded animals, and the compound 2,2',2"-[s-phenenyltris(sulfonylimino)]tris[2-deoxy-D-glucopyranose] which is a new intermediate for the preparation of the active dodecakis (H-sulfate) compounds.
    Type: Grant
    Filed: April 4, 1977
    Date of Patent: October 17, 1978
    Assignee: American Cyanamid Company
    Inventors: Vijay Gopalan Nair, Seymour Bernstein
  • Anionic substituted sulfonamido biphenyls
    Patent number: 4119784
    Abstract: Biphenyltetrayltetrakis(sulfonylimino)tetrabenzene dicarboxyic acid alkali metal salts, useful as complement inhibitors, and a biphenyltetrayltetrakis(sulfonylimino)tetrabenzene dicarboxylic acid octakis methoxyethyl ester that is a new intermediate for the preparation of the active salts.
    Type: Grant
    Filed: July 1, 1977
    Date of Patent: October 10, 1978
    Assignee: American Cyanamid Company
    Inventors: Ransom Brown Conrow, Seymour Bernstein
  • Anionic benzene tetrakis carbonylimino isophthalic acid salts
    Patent number: 4118585
    Abstract: Anionic substituted benzenetetrayltetrakis-(carbonylimino)tetraisophthalic acid salts, useful as complement inhibitors, and a methoxyethyl substituted benzenetetrayltetrakis(carbonylimino)tetraisophthalic acid ester that is a new intermediate for the preparation of the active salts.
    Type: Grant
    Filed: July 1, 1977
    Date of Patent: October 3, 1978
    Assignee: American Cyanamid Company
    Inventors: Ransom Brown Conrow, Seymour Bernstein
  • 2,6-Bis(1-piperidinoalkylideneamino)anthraquinones and method of treating cecal and hepatic amebic infections therewith
    Patent number: 4118498
    Abstract: Novel 2,6-bis(1-piperidinoalkylideneamino)anthraquinones that are effective against cecal and hepatic amebic infestations in warm-blooded animals are disclosed.
    Type: Grant
    Filed: November 15, 1977
    Date of Patent: October 3, 1978
    Assignee: American Cyanamid Company
    Inventors: Stanley Albert Lang, Jr., Paul Frank Fabio, Yang-I Lin, Keith Chadwick Murdock, Thomas Lynn Fields