Abstract: This invention provides an isolated nucleic acid molecule which encodes immunoglobulin receptor, Immunoglobulin superfamily Receptor Translocation Associated, IRTA, protein. Provided too, are the IRTA proteins encoded by the isolated nucleic acid molecules, IRTA1, IRTA2, IRTA3, IRTA4 or IRTA5 proteins, having the amino acid sequences set forth in any of FIG. 18A, 18B-1-18B-3, 18C-1-18C-2, 18D-1-18D-2 or 18E-1-18E-2. Oligonucleotides of the isolated nucleic acid molecules are provided. Antibodies directed to an epitope of a purified IRTA1, IRTA2, IRTA3, IRTA4 or IRTA5 proteins are also provided, as are pharmaceutical compositions comprising such antibodies or oligonucleotides. Methods for detecting a B cell malignancy in a sample from a subject; diagnosing B cell malignancy in a sample from a subject; detecting human IRTA protein in a sample; and treating a subject having a B cell cancer are also provided.

Abstract: This invention provides a process for sequencing single-stranded DNA employing modified nucleotides.

Abstract: An electrophotographic photoreceptor including a conductive substrate and a photosensitive layer located overlying the conductive substrate. The photosensitive layer comprises a specific diamine compound.

Abstract: The present invention provides compositions and methods for preventing, treating or reversing neuronal dysfunction in a mammal resulting from exposure to organophosphate nerve agents, organophosphate insecticides and incapacitating agents of the central nervous system (CNS); CNS injury, including traumatic brain injury, neurologic complications of cardiac surgery, perinatal asphyxia, and stroke, spinal cord injury, and peripheral nerve injury; and neuronal disorders associated with the loss of motor function including post-polio syndrome, amyotrophic lateral sclerosis, myasthenia gravis, Parkinson's disease and Rett syndrome; neurodegenerative disorders including Alzheimer's disease, mild cognitive impairment and schizophrenia; and cognitive impairment associated with aging.

Abstract: The present invention relates to substituted bicyclic tetrahydropyrrole compounds of general formula (I), methods for their preparation, medicaments comprising these compounds as well their use in the manufacture of a medicament for the treatment of humans and animals.

Abstract: A recording medium contains a support, and an antistatic agent-containing layer, and the antistatic agent-containing layer contains a binder resin and tin oxide-coated titanium oxide particles.

Abstract: An image forming apparatus for forming an image on a recording medium includes a belt configured to travel rotationally and looped around at least two rotary support members, a driven rotary member disposed facing at least one of the rotary support members via the belt and configured to rotate with the belt, and a controller. The controller is configured to minimize fluctuation in one of a travel velocity and a travel distance of the belt by controlling the travel of the belt based on one of a rotational angular displacement and a rotational angular velocity of each of the rotary support member and the driven rotary member.

Abstract: A constant current output control type switching regulator that reduces the number of parts, resolves the loss of the current running in the resistor, and eliminates the need to change the time constant of the integrator due to changing the inductor value. The switching regulator creates the adjustment reference voltage by multiplying the proportion of Vout/Vin by the reference voltage, and when the clock signal is high, the current sense voltage is sampled when the current of the initial current value runs in the switching transistor, and when the clock signal is low, the potential difference between the adjustment reference voltage and the sampled current sense voltage is added to the adjustment reference voltage and creates the second reference voltage; and with the signal CPOUT controls the operation of the transistors upon execution of PWM control.

Abstract: A draining device for air control equipment has a bottom shell, a top shell, a knob, a switch and a connecting device. The bottom and top shells are connected to each other. The top shell has two inclined recesses. The knob is mounted through the top shell and has two sliding protrusions mounted in the inclined recesses and two tabs. The switch is mounted in the bottom shell and has a button. The connecting device has a connecting tube, a flange and an end protrusion. The connecting tube is mounted through the top shell. The flange is formed around the connecting tube and is mounted across the tabs. The end protrusion abuts the button. When the knob is rotated, the sliding protrusions move along the inclined recesses to force the knob moving downward. Therefore, the end protrusion pushes the button to turn on the switch.

Abstract: A disclosed operation control method of a charge pump circuit for boosting an input voltage to a desired magnitude in the range between the input voltage and twice the input voltage and outputting the boosted voltage. The method includes the steps of (a) during a charging period, charging, with the input voltage, one or more of the capacitors connected in series by selectively turning on one or more of the first switches in accordance with the desired voltage magnitude, turning on the third switch, and selectively turning on the second switch or one of the fourth switches; and (b) during a discharging period, turning off the third switch and the second switch or the fourth switch having been turned on; selectively turning on one or more of the first switches; and turning on one or more fourth and the fifth switches.

Abstract: An electrophotographic photoreceptor including a conductive substrate, a photosensitive layer, and a surface layer, which satisfies the following inequations: 0.005<WRa(LMH)<0.03??(i) 0.010<WRa(LHH)<0.03??(ii) 0.005<WRa(LML)<0.20??(iii) WRa(LLH)>WRa(LMH)??(iv) WRa(LLH)>WRa(LHH)??(v) wherein WRa (?m) represents a center-line average roughness of frequency components LHH, LHL, LMH, LML, LLH, and LLL that are obtained by subjecting a one-dimensional data array of a surface profile of the electrophotographic photoreceptor to wavelet transformation multiresolution analysis so as to be separated into 6 frequency components; thinning a one-dimensional data array of the lowest frequency component so that the number of data array is reduced to 1/40; and subjecting the thinned one-dimensional data array to wavelet transformation multiresolution analysis so as to be separated into the 6 frequency components LHH, LHL, LMH, LML, LLH, and LLL.

Abstract: A method for erasing an image including irradiating an image formed on a thermoreversible recording medium with a laser light having a wavelength of 700 nm to 1,500 nm so as to erase the image, wherein an energy density of the laser light is in a range of the energy density which can erase the image and more than a center value of the range, wherein the thermoreversible recording medium includes a support, and a thermoreversible recording layer on the support, and wherein the thermoreversible recording layer contains a leuco dye serving as an electron-donating color-forming compound and a reversible developer serving as an electron-accepting compound, in which color tone reversibly changes by heat, and at least one of the thermoreversible recording layer and a layer adjacent to the thermoreversible recording layer contains a photothermal conversion material, which absorbs the light and converts the light into heat.

Abstract: A disclosed constant current supply type switching regulator includes a switching element configured to activate a switch operation depending on an input control signal, an inductor configured to be charged with the input voltage in response to the switching element activating the switch operation, a rectification element configured to discharge the inductor in response to the switching element shifting to a cutoff state, a current detection circuit unit configured to generate a current proportional to a current flowing into the switching element and generate and supply a current sense voltage depending on the proportional current and a control circuit unit configured to average the current sense voltage supplied from the current detection circuit unit and perform PWM (Pulse Width Modulation) control on the switching element for supplying a constant current in order to force the averaged voltage to be equal to a first reference voltage.

Abstract: The present invention provides enzymes capable of hydrolysing organophosphate (OP) molecules. In particular, the invention provides a phosphotriesterase enzyme identified from an Agrobacterium radiobacter strain isolated from soil that hydrolyses OP pesticides, and the gene encoding that enzyme. The invention also provides mutants of the identified phosphotriesterase enzyme which have altered substrate specificity. The use of these enzymes in bioremediation strategies is also provided.

Abstract: Methods of addressing a biomolecule to a selectively addressable electrode are described. A permeation layer overlying a plurality of selectively addressable electrodes is provided. The permeation layer includes a reactive group that is adapted to bond to a biomolecule and that requires activation through a chemical transformation before bonding to the biomolecule. At least one selectively addressable electrode is biased such that a pH change occurs in an overlying solution of the at least one selectively addressable electrode. The reactive group in a portion of the permeation layer above the at least one selectively addressable electrode is then chemically transformed to an activated reactive group as a result of the pH change. A biomolecule is then bound to the permeation layer overlying the at least one selectively addressable electrode through the activated reactive group.

Abstract: The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and docosahexaenoic acid, in recombinant cells such as yeast or plant cells. Also provided are recombinant cells or plants which produce long-chain polyunsaturated fatty acids. Furthermore, the present invention relates to a group of new enzymes which possess desaturase or elongase activity that can be used in methods of synthesizing long-chain polyunsaturated fatty acids.

Abstract: When a control circuit detects from a signal CPO4 that a battery voltage is less than a sixth reference voltage, a constant current operation in VFM control is performed with respect to a switching transistor and a synchronous rectification transistor in accordance with signals RVDET and CPO3. Furthermore, when the control circuit detects from the signal CPO4 that the battery voltage becomes equal to or greater than the sixth reference voltage, the constant current operation in PWM control is performed in accordance with a signal CPO2. When an output signal CVDET from a constant current/constant voltage switching detection circuit becomes high level, operation control with respect to the switching transistor and the synchronous rectification transistor is switched from the PWM control of constant current operations to the PWM control of constant voltage operations in accordance with a signal CPO1.

Abstract: A method and system for acquiring, processing, storing, and displaying x-ray mammograms Mp tomosynthesis images Tr representative of breast slices, and x-ray tomosynthesis projection images Tp taken at different angles to a breast, where the Tr images are reconstructed from Tp images.

Abstract: An image display apparatus according to the invention comprises reading section (11a) which reads in an image data set of a subject acquired by a medical imaging apparatus (2) from a data recording device (13) which stores the image data set; input sections (16, 17) which input a desired object organ to the read-in image data set; object organ extracting section (11b) which extracts the inputted object organ; reference position setting section (11h) which sets a reference position for producing an unfolded image in the circumferential direction of the bore of the extracted object organ; calculating device (11e) which calculates pixel information in the circumferential direction of the bore of the object organ from the set reference position; and image display section (15) which displays the calculated pixel information in the circumferential direction of the bore of the object organ.

Abstract: An image erasing apparatus including: a semiconductor laser array in which a plurality of semiconductor laser light sources are linearly aligned; a width direction collimating unit provided on an output surface of the semiconductor laser array, and configured to collimate, in a width direction, broadening of laser beams emitted from the semiconductor laser array so as to form a linear beam; and a length direction light distribution controlling unit configured to control a length of a major axis of the linear beam to be longer than a length of a major axis of an emission part of the semiconductor laser array, and to attain uniform light distribution in the length direction of the linear beam; wherein the linear beam, which has the major axis whose length is longer than the length of the major axis of the emission part of the semiconductor laser array and uniform light distribution in the length direction thereof, is to be applied to and heat a thermoreversible recording medium, in which any of transparency and