Patents Represented by Attorney Denis A. Polyn

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  • Treatment of zinc plant leach residues for recovery of the contained metal values
    Patent number: 4225342
    Abstract: A process for treating zinc plant leach residues for the recovery of the lead, silver, and tin values contained therein is disclosed. The process includes the treatment of the zinc plant residue with concentrated sulphuric acid followed by water leaching and other hydrometallurgical steps to separately recover the lead, silver and tin.
    Type: Grant
    Filed: September 21, 1979
    Date of Patent: September 30, 1980
    Assignee: Texasgulf Inc.
    Inventors: George M. Freeman, David E. Nightingale
  • 15-Deoxy-16-hydroxy-16-substituted prostanoic acids and congeners
    Patent number: 4192950
    Abstract: This disclosure describes novel 15-deoxy-16-hydroxy-16-substituted prostanoic acids and congeners thereof having utility as bronchodilators as hypotensive agents, and as agents for the control of excessive gastric secretion.
    Type: Grant
    Filed: September 22, 1977
    Date of Patent: March 11, 1980
    Assignee: American Cyanamid Company
    Inventors: Middleton B. Floyd, Jr., Martin J. Weiss, Charles V. Grudzinskas, Sow-Mei L. Chen
  • 11-(2-Hydroxyethylthio)prostenoic acid E series derivatives
    Patent number: 4189597
    Abstract: This disclosure describes certain 11-(2-hydroxyethylthio)-9-keto-prostenoic acid E series derivatives, and their intermediates, useful as bronchodilators and inflammatory medeator release inhibitors.
    Type: Grant
    Filed: October 17, 1977
    Date of Patent: February 19, 1980
    Assignee: American Cyanamid Company
    Inventors: Martin J. Weiss, Gerald J. Siuta
  • Prostenoic acids and esters
    Patent number: 4178456
    Abstract: This disclosure describes derivatives, analogs, and congeners of prostanoic acid having a terminal cyclic moiety in the .beta.-chain which possess the pharmacological activities associated with the prostaglandins.
    Type: Grant
    Filed: March 30, 1977
    Date of Patent: December 11, 1979
    Assignee: American Cyanamid Company
    Inventors: Allan Wissner, Martin J. Weiss, Karel F. Bernady
  • 15-Deoxy-16-hydroxy-16-substituted-3-thia-prostanoic acids
    Patent number: 4131737
    Abstract: This disclosure describes novel 15-deoxy-16-hydroxy-16-substituted prostanoic acids and conomers thereof having utility as bronchodilators as hypotensive agents, and as agents for the control of excessive gastric secretion.
    Type: Grant
    Filed: March 30, 1977
    Date of Patent: December 26, 1978
    Assignee: American Cyanamid Company
    Inventors: Middleton B. Floyd, Jr., Martin J. Weiss, Charles V. Gredeinskas, Sow-mei C. Chen
  • Novel 11-hydroxy-9-keto-5,6-cis-13,14-cis-prostadienoic acid derivatives
    Patent number: 4123456
    Abstract: This disclosure describes certain 11-hydroxy and 11-deoxy-9-keto(or hydroxy)-prostanoic acid derivatives useful as bronchodilators, hypotensive agents, anti-ulcer agents, or as intermediates.
    Type: Grant
    Filed: February 17, 1977
    Date of Patent: October 31, 1978
    Assignee: American Cyanamid Company
    Inventors: Karel F. Bernady, Middleton B. Floyd, Jr., John F. Poletto, Robert E. Schaub, Martin J. Weiss
  • Novel 16 hydroxy 15-deoxy-5-cis-prostenoic acids and esters
    Patent number: 4107441
    Abstract: This disclosure describes certain hydroxy substituted 15-deoxy-5-cis-prostenoic acids and esters useful as hypotensive agents, anti-ulcer agents, bronchodilators, anti-microbial agents, anticonvulsants, or as intermediates.
    Type: Grant
    Filed: August 26, 1975
    Date of Patent: August 15, 1978
    Assignee: American Cyanamid Company
    Inventors: Middleton Brawner Floyd, Jr., Martin Joseph Weiss, William James McGahren, Robert Eugene Schaub
  • 1-Alkoximino-2-(.omega.-substituted-alkyl)-2-cyclopentenes
    Patent number: 4094896
    Abstract: This disclosure describes certain 1-alkoximino-2-(.omega.-substituted-alkyl)-2-cyclopentenes useful as intermediates for the preparation of homologues, analogues, congeners, and derivatives of 9-oxo-13-trans-prostenoic acid and of 9-hydroxy-13-trans-prostenoic acid which have antimicrobial activity and prostaglandin-like hypotensive activity.
    Type: Grant
    Filed: December 2, 1976
    Date of Patent: June 13, 1978
    Assignee: American Cyanamid Company
    Inventors: Karel Francis Bernady, John Frank Poletto, Martin Joseph Weiss
  • Substituted benzodiazepines and method of use
    Patent number: 4087421
    Abstract: 10-Substituted amino-4,9-dihydro-4H-thieno[3,4-b][1,5]benzodiazepines having neuroleptic, anti-depressant and analgesic activity.
    Type: Grant
    Filed: January 27, 1977
    Date of Patent: May 2, 1978
    Assignee: American Cyanamid Company
    Inventor: Sidney Robert Safir
  • 11-(2-Hydroxyethylthio)prostenoic acid E.sub.2 series derivatives
    Patent number: 4085272
    Abstract: This disclosure describes certain 11-(2-hydroxyethylthio)-9-keto-prostenoic acid E series derivatives, and their intermediates, useful as bronchodilators and inflammatory medeator release inhibitors.
    Type: Grant
    Filed: March 30, 1977
    Date of Patent: April 18, 1978
    Assignee: American Cyanamid Company
    Inventors: Martin Joseph Weiss, Gerald Joseph Siuta
  • Derivatives of .alpha.-(6-carboxyhexyl) furfuryl alcohol
    Patent number: 4076732
    Abstract: This disclosure describes novel derivatives of .alpha.-(6-carboxyhexyl) furfuryl alcohol which are useful as intermediates for the preparation of natural prostaglandins and their congeners.
    Type: Grant
    Filed: March 30, 1977
    Date of Patent: February 28, 1978
    Assignee: American Cyanamid Company
    Inventor: Middleton Brawner Floyd, Jr.
  • Cycloalkyl and cycloalkenyl prostaglandin congeners
    Patent number: 4076947
    Abstract: This disclosure describes novel 15-hydroxy prostanoic acids and derivatives thereof useful as bronchodilators, hypotensive agents and gastric acid secretion inhibitors (anti-ulcer).
    Type: Grant
    Filed: January 12, 1977
    Date of Patent: February 28, 1978
    Assignee: American Cyanamid Company
    Inventors: Robert Eugene Schaub, Martin Joseph Weiss
  • Benzothienylisocyanates and isothiocyanates and method of preparation thereof
    Patent number: 4069231
    Abstract: This invention relates to 4,5,6,7-tetrahydrobenzo[b]thien-4-yl isocyanates and 4,5,6,7-tetrahydrobenzo[b]thien-4-yl isocyanates and methods for the preparation thereof. These compounds are useful in the manufacture of substituted urea derivatives which are useful as animal growth regulants and herbicides.
    Type: Grant
    Filed: October 22, 1976
    Date of Patent: January 17, 1978
    Assignee: American Cyanamid Company
    Inventor: Goro Asato
  • 15-Deoxy-16-hydroxy-16-vinyl and cyclopropyl substituted prostanoic acids and congeners
    Patent number: 4061670
    Abstract: This disclosure describes novel 15-deoxy-16-hydroxy-16-substituted prostanoic acids and congeners thereof having utility as bronchodilators as hypotensive agents, and as agents for the control of excessive gastric secretion.
    Type: Grant
    Filed: July 19, 1976
    Date of Patent: December 6, 1977
    Assignee: American Cyanamid Company
    Inventors: Middleton Brawner Floyd, Jr., Martin Joseph Weiss, Charles Vincent Grudzinskas, Sow-Mei Lai Chen
  • Derivatives of 9-hydroxy-13-trans-prostenoic acid
    Patent number: 4061672
    Abstract: This disclosure describes certain 15-deoxy prostanoic acid derivatives having a hydroxy group further along in the beta-chain, useful as bronchodilators, hypotensive agents, anti-ulcer agents, or as intermediates.
    Type: Grant
    Filed: January 26, 1976
    Date of Patent: December 6, 1977
    Assignee: American Cyanamid Company
    Inventors: Middleton Brawner Floyd, Jr., William James McGahren, Robert Eugene Schaub, Martin Joseph Weiss
  • Novel 3-triphenylmethoxy-1-alkynes, 3-triphenyl-methoxy-1-trans-alkenyl-dialkyl-alanes, and lithium 3-triphenylmethoxy-1-trans-alkenyl-dialkyl alanates
    Patent number: 4060540
    Abstract: This disclosure describes 3-triphenylmethoxy-1-alkynes, 3-triphenylmethoxy-1-trans-alkenyl-dialkyl-alanes, and lithium 3-triphenylmethoxy-1-trans-alkenyl-dialkyl alanates useful as intermediates for the preparation of certain 11-hydroxy- and 11-deoxy-9-keto(or hydroxy)-prostanoic acid derivatives which possess bronchodilator, hypotensive, and anti-ulcer activity.
    Type: Grant
    Filed: November 5, 1976
    Date of Patent: November 29, 1977
    Assignee: American Cyanamid Company
    Inventors: Karel Francis Bernady, Middleton Brawner Floyd, Jr., John Frank Poletto, Robert Eugene Schaub, Martin Joseph Weiss
  • Polysubstituted-alkyl esters of 4-alkylaminobenzoic acids
    Patent number: 4058550
    Abstract: Polysubstituted-alkyl esters of 4-alkylaminobenzoic acids having hypolipemic activity.
    Type: Grant
    Filed: October 28, 1975
    Date of Patent: November 15, 1977
    Assignee: American Cyanamid Company
    Inventors: Robert Gordon Shepherd, Thomas Gary Miner
  • Novel 11-deoxy-substituted prostaglandins of the E and F series
    Patent number: 4057571
    Abstract: This disclosure describes 11-deoxy-11-substituted members of the E.sub.2, F.sub.2, E.sub.1, F.sub.1, dihydro E.sub.1 and dihydro F.sub.1 prostaglandin series which are useful as hypotensive agents and as anti-ulcer agents.
    Type: Grant
    Filed: February 24, 1975
    Date of Patent: November 8, 1977
    Assignee: American Cyanamid Company
    Inventors: Charles Vincent Grudzinskas, Martin Joseph Weiss
  • Amide derivatives of 9-oxo-13-trans-prostenoic acid
    Patent number: 4054604
    Abstract: This disclosure describes homologues, analogues, congeners, and derivatives of 9-oxo-13-trans-prostenamide and of 9-hydroxy-13-trans-prostenamide, having antimicrobial activity and prostaglandin-like hypotensive activity.
    Type: Grant
    Filed: May 13, 1976
    Date of Patent: October 18, 1977
    Assignee: American Cyanamid Company
    Inventors: Karel Francis Bernady, Middleton Brawner Floyd, Jr., John Frank Poletto, Robert Eugene Schaub, Martin Joseph Weiss
  • Hydroxylated 15-deoxy derivatives of 9-hydroxyl-13-trans-prostenoic acid
    Patent number: RE29469
    Abstract: This disclosure describes certain 15-deoxy prostanoic acid derivatives having a hydroxy group further along in the beta-chain, useful as bronchodilators; hypotensive agents, anti-ulcer agents, or as intermediates.
    Type: Grant
    Filed: May 3, 1976
    Date of Patent: November 8, 1977
    Assignee: American Cyanamid Company
    Inventors: Middleton Brawner Floyd, Jr., William James McGahren, Robert Eugene Schaub, Martin Joseph Weiss