Abstract: The present invention relates to pharmaceutical compositions useful for treating or preventing gastrointestinal disorders. These compositions comprise a bismuth-containing agent, preferably a campylobacter-inhibiting bismuth-containing agent such as bismuth subsalicylate and bismuth subcitrate, and a histamine-2 receptor blocking anti-secretory agent such as cimetidine.The present invention further relates to methods for treating or preventing gastrointestinal disorders in humans or lower animals by administering a bismuth-containing agent and a histamine-2 receptor blocking anti-secretory agent.
Abstract: A process for making a bismuth-containing solid dose form composition is described which includes an agglomeration step with binder in a high shear mixer.
Type:
Grant
Filed:
March 24, 1994
Date of Patent:
March 21, 1995
Assignee:
The Procter & Gamble Company
Inventors:
Francis B. Chapura, Daniel L. Barone, Michael G. Colacino
Abstract: Laxative compositions containing sennoside and menthol, pharmaceutically-acceptable esters of menthol, or mixtures thereof, preferably as peppermint oil; and methods for treating constipation by orally concurrently administering to the lower gastrointestinal tract of a person in need of such treatment sennoside and menthol.
Abstract: The present invention relates to oral compositions in the form of microcapsules which reduce oral bacteria and provide long lasting breath protection.
Abstract: Agglomerated psyllium husk comprising edible acid uniformly dispersed throughout the agglomerating coating. Preferred are maltodextrin-containing agglomerates of psyllium husk comprising citric acid uniformly dispersed throughout the maltodextrin coating. This agglomerated psyllium husk has improved mixability and dispersibility in liquids.
Abstract: Psyllium husk-containing powdered drink mix compositions comprising a free radical scavenging antioxidant material to reduce the incidence of vacuum generation in air tight containers and of off-odors.
Abstract: Disclosed are stabilizer compositions comprising specific mixed partial salts of a lower alkyl vinyl ether-maleic acid copolymer wherein said partial salts containing from about 15% to about 40% free acid, and as the cationic salt function:(a) from about 0.1% to about 80% strontium cations; and(b) from about 0.1% to about 65% zinc cationsof the total initial carboxyl groups reacted. Also disclosed are denture stabilizing compositions comprising these mixed partial salts, as well as denture stabilizing compositions comprising a safe and adhesively effective amount of two or more denture adhesive components wherein one of said denture adhesive components is the mixed partial salt(s) of the present invention.
Type:
Grant
Filed:
October 22, 1992
Date of Patent:
April 19, 1994
Assignee:
The Procter & Gamble Company
Inventors:
Jayanth Rajaiah, Abel Saud, Bruce J. MacKay
Abstract: Disclosed are oral compositions which are effective against plaque and gingivitis and contain a noncationic water insoluble antibacterial agent.
Abstract: Disclosed are oral compositions which are effective against plaque and gingivitis and contain a noncationic water insoluble antibacterial agent.
Abstract: This disclosure relates to drug-polymer matrix compositions comprising an active ingredient having an amine or amido group and a pharmaceutically acceptable copolymer having a plurality of carboxylic acid and ester groups wherein the matrix dissociates in a media having a pH of less than 4, thereby releasing the active ingredient into the media.
Abstract: This invention relates to compositions and methods for treating diseases of the oral cavity in humans and lower animals using a glycerol monooleate gel for releasing drugs in the oral cavity.
Abstract: Ingestible pharmaceutical compositions comprising pharmaceutical actives useful for treating upper gastrointestinal tract distress (e.g., antacid agents) and 3-1-menthoxy propane 1,2-diol in amounts effective for providing a cooling sensation to the throat.
Abstract: Psyllium husk-containing drink mix compositions comprising the divalent cation salt of strong inorganic acids selected from the group consisting of magnesium sulfate, calcium sulfate, calcium chloride, zinc sulfate, zinc chloride and mixtures thereof.
Abstract: Unflavored psyllium husk-containing drink mix compositions are prepared consisting essentially of small particle size psyllium husk comprising less than about 10% of psyllium husk having particle sizes larger than about 60 mesh screen, less than about 2.0% edible acid, and sugar. Such compositions are unflavored so as to permit mixing small particle size psyllium, which is readily suspended in a liquid without a gritty texture, with a broader selection of liquids, such as milk and fruit drinks, without rapid gelling of the psyllium husk.
Type:
Grant
Filed:
October 21, 1991
Date of Patent:
August 10, 1993
Assignee:
The Procter & Gamble Company
Inventors:
Melvin A. Barbera, Larry E. Burns, Amy M. Martini
Abstract: Psyllium husk-containing drink mix compositions comprising small particle size psyllium husk and edible, water soluble salts. The edible, water soluble salts are present at a level sufficient to reduce the gellation rate of the psyllium husk when dispersed in an aqueous solution.
Abstract: The present invention relates to laxative compositions comprising psyllium and sennoside wherein sennoside is dispersed in a palatable food grade fat having a melting point within the range of from about 30.degree. C. to about 50.degree. C.