Abstract: The invention provides a process for the production of 3-(1-amino-1,3-dicarboxy-3-hydroxy-but-4-yl) indole and certain salts and internal condensation products thereof. An unsaturated indolyl ester is reacted with ethylchloro(hydroxyimino)acetate in the presence of triethylamine in an organic solvent to cause a 1,3-dipolar addition reaction to form a di-ester. The di-ester is saponified to form a di-acid which di-acid is then reduced to form either the product indole or a salt thereof.

Abstract: The present invention relates to heterocyclic compounds characterized in that they correspond to the general formula I: ##STR1## in which R.sub.1 represents a hydrogen atom or a halogen, n can have the values 1 to 6 and Het represents an azole, or one of its derivatives selected from among imidazole, indazole, tetrahydroindazoles, pyrazole or pyrazoline and which can be represented by the general formula II: ##STR2## in which A and B, always different, represent a carbon atom or a nitrogen atom, the dashed line indicates the possible presence of a double bond between positions 4 and 5, and R.sub.2, R.sub.3 and R.sub.

Abstract: An apparatus for filling containers includes a food product fill pump having a valve member and pump piston operated by respective cam drives. A servo-controlled drive motor drives the cams, whereby the speed of the pump operation can be controlled independently of an associated container conveyor. Significantly, the servo-control of the apparatus permits the pump piston of the food pump to be operated during its container-filling advancing stroke at a substantially constant speed, while the pumping cycle time is selectively varied by selectively varying the speed of the piston retraction stroke.

Abstract: A heat-retaining food service container includes an outer shell assembly, and an expandable inner container arrangement within which is disposed a mass of heat-fusible material. Attendant to heating of the heat-fusible material to an elevated temperature, the material undergoes a phase change and expansion. The expandable inner container arrangement accommodates such expansion of the fusible material, while avoiding any appreciable deformation of the outer shell assembly. The construction promotes efficient heat-transfer to food within the container.

Abstract: A method and apparatus for polishing a condensate is provided wherein the condensate contains both suspended and colloidally dispersed solid impurities, and also intermittent and variable levels of ionic impurities and dissolved silica. When the ionic impurities exceed a preselected level, a finely divided ion exchange resin mixture is first admixed with the condensate at a rate sufficient to reduce the level of such impurities to a preselected level within a preselected contact time period. Thereafter, the resulting condensate is passed through a membrane filtration device to remove such suspended and dispersed solid impurities. A simple, effective and reliable retrofittable apparatus adapted for use with BWR's fitted with precoat filter systems is provided.

Abstract: An analog-ligand having a conformation that substantially corresponds to the conformation of a hydrolytic transition state of an amide or ester reactant ligand is used to produce receptor molecules of predetermined specificity. The receptor molecules include an antibody combining site that binds to the analog-ligand and also to a reactant ligand and thereby stabilizes the tetrahedral carbon atom of the amide or ester hydrolysis transition state of that reactant ligand to catalytically hydrolyze the reactant ligand at a predetermined site.

Abstract: A receptacle for receiving soiled articles including a bag which is disposed in and secured to a rotatably mounted holder. The holder is rotated to open and close the bag in response to movement of a foot pedal which opens the bag when the receptacle is opened and closes the bag when the receptacle is closed.

Abstract: A container for storing and pouring a liquid, such as motor oil, has top, bottom, and lateral walls, a spout extending upwardly from the top wall, and two interior partitions, which are horizontal in an upright position of the container. Each partition defines an orifice extending between such partition and a side wall. The partitions divide the container into primary, secondary, and tertiary chambers. The primary chamber, which is the lowest chamber when the container is upright, has a volume sufficient to contain a predetermined quantity of motor oil. The secondary and tertiary chambers have substantially smaller volumes. The partitions prevent the primary chamber from being emptied of a liquid, when the container is rotated in a prescribed direction, unless the container is inverted sufficiently to incline, at an angle of approximately 8.degree. from horizontal, a planar surface being defined by each partition and facing the other partition.

Abstract: A photoconductor element is provided that has non-blurring latent image keeping memory which is suitable for multiple electrophotographic copying from a single imaging step. The element preferably incorporates a charge generation layer which comprises a phthalocyanine dye or pigment. The copying method involves simultaneous application of corona charge and an image exposure to the element followed by uniform irradiation of the element. Thereafter a plurality of copies can be made by the step sequence of toner deposition, toner transfer, and toner heat fusion to a receiver.

Abstract: A method for prolonging a hydroconversion catalyst life-time is provided. An additive functional to partially redirect the deposition of catalytic poisoning agents on the catalyst is utilized. The additive may comprise a chemically inert, porous carbonaceous material or ferruginous clay.

Abstract: Magnetic carrier core particles are provided which are coated with a Werner complex. The coating is readily accomplished by dispersing magnetic core particles in a solution of the Werner type complex. A hydroxyl group containing polymer can also be present which functions to enhance coating thickness. The Werner complexes are highly reactive, bond strongly to hydroxyl groups, and absorb readily into the core particles. Coated particles display excellent useful life capability and developer compositions containing such coated cores produce high resolution developed images.

Abstract: A molded oil pan gasket having an integrally formed pair of elastomeric side sections and pair of elastomeric end sections and a rail in each of the side sections. Each rail is an elongated rigid thermoplastic member having a generally flat main body of a first thickness and a plurality of integrally formed, longitudinally spaced stops. Each stop provides a fastener opening. The stops are of a height substantially greater than the first thickness, but less than the thickness of the associated side section. A plurality of apertures are formed in each rail for integrating the rail and the elastomer of the associated side section. A series of abutments and stiffening ribs are also disclosed.

Abstract: An apparatus is disclosed suitable for presenting a container at a labeling station where the container is oriented before, during or after the time a label is affixed to the container. The apparatus includes a turntable that is rotatable about a fixed axis. A turret is provided on the turntable for rotation about a turret axis substantially parallel to the fixed axis. The turret is adapted to receive a container. A cam follower carriage is mounted to the turntable for reciprocal movement along the turret axis and is operatively engaged with the turret for rotating the turret when reciprocated. Reciprocal movement is imparted to the carriage by a lower cam.

Abstract: A laminated gasket assembly and method of making same is disclosed. The laminated gasket assembly comprises first and second sheets, each having a thin metallic layer having a thin elastomeric coating on at least one major surface, and an elastomeric layer interposed between, and joining, the sheets, with first and second thin elastomeric coatings facing outwardly in opposite directions. The gasket assembly defines at least one elevated pressure service opening therethrough. The sheets and layers are laminated and define an embossment around a service opening, with the elastomeric layer being conformed to the embossment.

Abstract: An easy-open container includes a membrane forming the top edge of the container and hermetically sealing the contents thereof. Elements for opening the container are disposed on the membrane, and includes a first bead of thermoplastic material and a first perforated line for tearing across the membrane. In one embodiment the membrane is disposed inward from the mouth of the bag, leaving portions of the bag walls extending upward beyond the container top edge to form guide rails which facilitate opening of the container. One guide rail is removed as the bag is opened and remaining portions of the bag walls are offset to enhance access to the bag contents. A membrane for sealing the mouth opening of a bag-like structure is also provided, as are methods for making an easy-open container and for making a membrane having the strcutures aforesaid.

Abstract: A load sensing gasket having a gasket body defining a service opening for fluids and having a load sensor encased in a cavity in the body. The gasket body comprises a first gasket layer providing a first outer gasketing surface and a first inner surface, a second gasket layer providing a second outer gasketing surface and a second inner surface, the inner surfaces together defining the cavity and side walls for defining a perimeter for the cavity. The load sensor includes confronting electrodes and a pressure sensitive electrically resistive material between the electrodes and conductors extending outwardly of the perimeter. A seal between the first and second gasket layers around the load sensor seals the electrodes in the cavity from fluids when the gasket is in use.

Abstract: Antigens, immunogens, inocula, antibodies, and particularly diagnostic methods and systems relating to Epstein-Barr virus nuclear antigen (EBNA) are disclosed. The diagnostic methods and systems utilize a synthetic, random copolymer polypeptide containing about 8 to about 40 amino acid residues that includes the overlapping five and six amino acid residue sequences--Gly--R.sup.1 --Gly--R.sup.2 --Gly-- (i)wherein R.sup.1 and R.sup.2 are amino acid residues selected from Ala, Asn, Arg, Gly, Leu, Pro, Ser, and Thr with the provision that R.sup.1 and R.sup.2 are not both Gly; and--Gly--Ala--Gly--Gly--Ala--Gly--. (ii)The polypeptide contains at least 50 mole percent Gly residues. The diagnostic method and system are particularly useful for assaying for the stage of mononucleois disease, and the presence of nasopharynegeal carcinoma.