Abstract: 7,8-Disubstituted quanosine nucleoside derivatives are found to be potent immune response enhancing agents in human and animal cells. 7-Substituents are hydrocarbyl radicals having a length greater than ethyl and less than about decyl. 8-Substituents are .dbd.O, .dbd.S, .dbd.Se and .dbd.NCN. Compositions and methods of use are also disclosed.

Abstract: A lockable valve mechanism for introducing a liquid sample into an associated reaction vessel includes a valve body, and a valve member rotatably mounted thereon. The valve member is movable from an open position, wherein inlet and outlet passages of the valve mechanism are aligned for introduction of a sample into the reaction vessel, to a closed and sealed position, wherein the outlet passage of the valve body is sealed. The valve member includes a locking arrangement to prevent movement of the valve member out of the closed and sealed position after movement from the open position into the sealed position.

Abstract: A bander assembly for effecting a substantially even distribution of granular or particulate matter across a relatively wide band. The bander assembly includes a housing defining a throat section and a distributor section. The throat section has a series of baffles arranged toward one end thereof for agitating the granular material as it flows therepast. A series of deflectors are arranged in the distributor section for deflecting the granular material into a wide band having a substantially even or equal distribution thereacross. The present invention also relates to a method for effecting a substantially even or equal distribution of granular material from a bander assembly.

Abstract: A composition for the treatment of patients having Acquired Immune Deficiency Syndrome comprising approximately 2 to 7 percent by weight soybean oil and approximately 1 to 2 percent by weight egg phosphatide and a method for the parenteral administration of this composition is disclosed.

Abstract: A collapsible storage rack assembly includes a plurality of upstanding, generally inverted U-shaped frame members between which extend a plurality of vertically spaced, hingedly collapsible shelf assemblies. The storage rack construction is preassembled, and can be easily and quickly opened for use by moving the frame members away from each other. In a similar manner, the storage rack can be easily collapsed by moving the frame members toward each other and into juxtaposition, with the shelf assemblies collapsing by upward hinging movement. In the closed and collapsed position, the shelf assemblies are substantially completely nested within the frame members, thereby facilitating convenient handling, shipment, and storage of the construction.

Abstract: An improvement in the process for the oxidative coupling of methane is provided. Typically, the reaction takes place in a reactor that includes a catalyst zone. A primary CH.sub.4 /O.sub.2 stream is fed into the entrance of the reactor and reacted at a temperature of 600.degree. C.-1000.degree. C. and a pressure of between 101 kPa and 800 kPa. The improvement comprises introducing an auxiliary oxygen stream directly into the catalyst zone and one or more points to thereby selectively increase the yield of C.sub.2+ products.

Abstract: The invention relates to a feed and to a process for its production. According to the process, a fatty substance is converted to the form of a metal salt of a fatty acid or fatty acids, and is combined with a carrier such as a concentrated feed. In the salt form the salt is protected in such a way that it will not disturb the disintegration taking place in the rumen of a ruminant, but it is, nevertheless, exploitable by the digestive system of the animal. What is essential in the invention is that the metal salt is formed into a three-dimensional matrix so that a substantially liquid fat or fatty acids remain in the cavities of the matrix. In a matrix form such as this the fat is fluid, and it can be transferred and batched like a liquid. It is possible to use vegetable oils which contain unsaturated fats and fatty acids for the production of a feed, whereby the fats and fatty acids can be caused, by means of the protection, to pass through the digestive system of a ruminant to the milk produced.

Abstract: A novel connector for connecting a beam to a column in a storage rack is disclosed. A flanged member is fitted against the column, with a side flange disposed against a side wall of the column and with a front flange disposed against a front wall of the column. Hooks on the front flange are hooked into apertures of the front wall. An elongate, strip-like spring clip is clipped onto the side flange, which has a recess receiving a bent portion of the spring clip. Another portion is accommodated by a trough extending from the recess. A dimple formed on the spring clip extends into a slot of the side flange. A locking pin affixed to the spring clip extends through an aperture of the side flange and through one of an array of apertures of the side wall.

Abstract: A bumper assembly for a shopping cart having a wire basket with horizontal wires bent so as to define a front corner of the basket. The assembly comprises a resilient, extruded, polymeric bumper having front, back, and side apertures extending longitudinally through the bumper, which is slotted so as to accommodate such wires at the front corner. The assembly comprises a pin extending through the back aperture with an interference fit so as to confine such wires between the pin and a front wall of the bumper. The front wall, which partly bounds the front aperture, is spaced from such wires when the front wall is unstressed. The front and side apertures lend enhanced cushioning ability to the bumper, which can yield in flexure, as well as in compression.

Abstract: The invention relates to the compounds corresponding to the general formula I ##STR1## in which: R.sup.1 represents a lower alkyl radical (having one to four carbon atoms), a phenyl radical or a benzyl radical. These compounds are useful as medicinal products or as synthesis intermediates for medicinal products.

Abstract: An apparatus transfers heat for the purpose of purifying raw feed liquid, separating dissolved gases from liquids, vaporizing heat transfer fluids or containing and regulating biological/chemical reactions. The feed liquid is directed into an evaporator module submerged in a solar pond or other body of heated liquid. The evaporator module includes a rotating housing through which a plurality of spaced apart substantially horizontal open ended heat transfer tubes extend. A heating liquid is directed through the heat transfer tubes. The feedwater is distributed within the evaporator module so as to cause the feedwater to descend into heat transferring contact with the heat transfer tubes and thereby vaporize a portion of the feedwater. A preferred embodiment of the evaporator module is disclosed which includes cavitation fins for urging the heated liquid through the evaporator module.

Abstract: A calibration fixture for a contact sensor for applying a uniform pressure to each contact sensor intersection and a method of using the fixture. The fixture includes a first plate against which a contact sensor is supported, a second plate confronting the first plate and spaced therefrom, an annular sealing member supported on the second plate, a bladder disposed between the sealing member and the second plate to define a fluid pressure chamber circumscribed by the sealing member, a frame for holding the first and second plates in their confronting relationship, and a pressurized fluid entry passage extending through the second plate and communicating with the pressure chamber.

Abstract: An apparatus for filling containers includes a food product fill pump having a valve member and pump piston operated by respective cam drives. A servo-controlled drive motor drives the cams, whereby the speed of the pump operation can be controlled independently of an associated container conveyor. Significantly, the servo-control of the apparatus permits the pump piston of the food pump to be operated during its container-filling advancing stroke at a substantially constant speed, while the pumping cycle time is selectively varied by selectively varying the speed of the piston retraction stroke.

Abstract: The present invention relates to heterocyclic compounds characterized in that they correspond to the general formula I: ##STR1## in which R.sub.1 represents a hydrogen atom or a halogen, n can have the values 1 to 6 and Het represents an azole, or one of its derivatives selected from among imidazole, indazole, tetrahydroindazoles, pyrazole or pyrazoline and which can be represented by the general formula II: ##STR2## in which A and B, always different, represent a carbon atom or a nitrogen atom, the dashed line indicates the possible presence of a double bond between positions 4 and 5, and R.sub.2, R.sub.3 and R.sub.

Abstract: The invention provides a process for the production of 3-(1-amino-1,3-dicarboxy-3-hydroxy-but-4-yl) indole and certain salts and internal condensation products thereof. An unsaturated indolyl ester is reacted with ethylchloro(hydroxyimino)acetate in the presence of triethylamine in an organic solvent to cause a 1,3-dipolar addition reaction to form a di-ester. The di-ester is saponified to form a di-acid which di-acid is then reduced to form either the product indole or a salt thereof.

Abstract: A photoconductor element of the type comprising successive layers of a support layer, a barrier layer, a charge generation layer, and an n-type charge transport layer wherein the barrier layer is less than about 1.0 micron in thickness and is comprised of (1) at least one monoethylenically unsaturated aliphatic dicarboxylic acid anhydride containing 4 through 8 carbon atoms per molecule, and (2) at least one vinyl monomer wherein the weight ratio of (1) to (2) is in the range of about 10:1 to 1:10.

Abstract: A heat-retaining food service container includes an outer shell assembly, and an expandable inner container arrangement within which is disposed a mass of heat-fusible material. Attendant to heating of the heat-fusible material to an elevated temperature, the material undergoes a phase change and expansion. The expandable inner container arrangement accommodates such expansion of the fusible material, while avoiding any appreciable deformation of the outer shell assembly. The construction promotes efficient heat-transfer to food within the container.

Abstract: A method and apparatus for polishing a condensate is provided wherein the condensate contains both suspended and colloidally dispersed solid impurities, and also intermittent and variable levels of ionic impurities and dissolved silica. When the ionic impurities exceed a preselected level, a finely divided ion exchange resin mixture is first admixed with the condensate at a rate sufficient to reduce the level of such impurities to a preselected level within a preselected contact time period. Thereafter, the resulting condensate is passed through a membrane filtration device to remove such suspended and dispersed solid impurities. A simple, effective and reliable retrofittable apparatus adapted for use with BWR's fitted with precoat filter systems is provided.

Abstract: An analog-ligand having a conformation that substantially corresponds to the conformation of a hydrolytic transition state of an amide or ester reactant ligand is used to produce receptor molecules of predetermined specificity. The receptor molecules include an antibody combining site that binds to the analog-ligand and also to a reactant ligand and thereby stabilizes the tetrahedral carbon atom of the amide or ester hydrolysis transition state of that reactant ligand to catalytically hydrolyze the reactant ligand at a predetermined site.