Patents Represented by Attorney, Agent or Law Firm Ellen K. Park
  • Patent number: 5112968
    Abstract: Compounds having the formula ##STR1## and pharmaceutically acceptable salts thereof which possess antibacterial activity.R.sub.s is a substituted hydroxy pyridone of the formulae: ##STR2## wherein Y.sub.1 is CH.sub.2 X; COOR.sub.6 ; CONR.sub.7 R.sub.8 ; OH; OCH.sub.2 R.sub.9 ; CHF.sub.2 ; CHO; CH.dbd.N--OR.sub.10 ; CH.dbd.CH--R.sub.11 ; CN; CH.dbd.N--NHR.sub.12, and Y.sub.2 is hydrogen; COOH; CONH.sub.2 ; CN; CSNH.sub.2 ; COO lower alkyl; CONR.sub.7 /R.sub.8.
    Type: Grant
    Filed: July 28, 1989
    Date of Patent: May 12, 1992
    Assignee: E. R. Squibb & Sons, Inc.
    Inventor: Uwe D. Treuner
  • Patent number: 5083899
    Abstract: A fluid driven turbine motor having a turbine shroud and a rotor assembly attached to a central portion within the turbine shroud. The rotor assembly includes a rotor and a plurality of vertical vanes mounted thereto and extending radially outward therefrom. The turbine shroud also includes a plurality of intake ports directing a fluid flow to the vanes. The intake ports are positioned such that the fluid flow directed by the intake ports exert balanced forces onto the vanes. The motor may optionally include a retractable centrifugal weight assembly and ports for draining moisture from the rotor assembly.
    Type: Grant
    Filed: April 12, 1990
    Date of Patent: January 28, 1992
    Assignee: Geph Enterprises, Inc.
    Inventor: Gerald W. Koch
  • Patent number: 5077432
    Abstract: Compounds having the formula ##STR1## and pharmaceutically acceptable salts thereof, wherein R.sub.3 and R.sub.4 are the same or different and each is hydrogen or alkyl or R.sub.3 and R.sub.4 taken together with the nitrogen atoms to which they are attached form a 1,2-diazacyclobutane, 1,2-diazacyclopentane, 1,2-diazacyclohexane, or 1,2-diazacycloheptane ring and Y, and Y.sub.2 are either hydrogen or hydroxy but are not the same; are useful chemical intermediates for the preparation of .beta.-lactam antibiotics.
    Type: Grant
    Filed: February 7, 1991
    Date of Patent: December 31, 1991
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Joseph E. Sundeen, Robert Zahler, Stefan Jendrzejewski
  • Patent number: 5068331
    Abstract: Compounds having the formula ##STR1## and pharmaceutically acceptable salts thereof, exhibit antibacterial activity wherein R is ##STR2##
    Type: Grant
    Filed: July 13, 1990
    Date of Patent: November 26, 1991
    Assignee: E. R. Squibb & Sons, Inc.
    Inventor: Uwe D. Treuner
  • Patent number: 5061767
    Abstract: A polymer composite, a method of making a polymer composite and a polymer composite membrane. The polymer composite comprises a uniform dispersion of hydrophobic polymeric particles in a continuous phase of a hydrophilic polymer. The new method of forming a polymer composite includes the formation of a concentrated emulsion of a hydrophilic monomer and a hydrophobic monomer and heating the concentrated emulsion at a predetermined temperature. The polymer composites of this invention may be useful as permselective membranes.
    Type: Grant
    Filed: April 5, 1990
    Date of Patent: October 29, 1991
    Assignee: State University of New York
    Inventors: Eli Ruckenstein, Jun S. Park
  • Patent number: 5059582
    Abstract: A superconducting laminate having at least one layer of metal and at least one layer of superconducting material. The metal layer and the superconducting layer are bonded. The metal later may also include carbon fibers from various precursors. The superconductor may be a composite material. The invention also includes a method of making the laminates.
    Type: Grant
    Filed: March 22, 1989
    Date of Patent: October 22, 1991
    Assignee: The Research Foundation of State University of NY
    Inventor: Deborah D. L. Chung
  • Patent number: 5037983
    Abstract: Compounds having the formula ##STR1## and pharmaceutically acceptable salts thereof and possessing antibacterial activiy, and intermediates to compounds of formula I having the formula ##STR2##
    Type: Grant
    Filed: December 1, 1989
    Date of Patent: August 6, 1991
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Joseph E. Sundeen, Peter H. Ermann
  • Patent number: 5030724
    Abstract: Antibacterial activity is exhibited by novel compounds having the formula ##STR1## or a pharmaceutically acceptable salt thereof. R.sub.3 and R.sub.4 are the same or different and each is hydrogen or alkyl or R.sub.3 and R.sub.4 taken together with the nitrogen atoms to which they are attached form a 1,2-diazacyclobutane, 1,2-diazacyclopentane, 1,2-diazacyclohexane, or 1,2-diazacycloheptane ring.Y.sub.1 and Y.sub.2 are either hydrogen or OR.sub.11 but are not the same.R.sub.11 is hydrogen, alkanoyl of from one to ten carbon atoms, substituted alkanoyl of from two to ten carbon atoms, phenylcarbonyl, (substituted phenyl) carbonyl, heteroarylcarbonyl, phenylalkanoyl, (substituted phenyl) alkanoyl, or heteroarylalkanoyl.
    Type: Grant
    Filed: January 22, 1990
    Date of Patent: July 9, 1991
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Joseph E. Sundeen, Robert Zahler, Stefan Jendrzejewski
  • Patent number: 5003092
    Abstract: Cyclopentadienyl compounds of aluminum, gallium and indium which when reacted at low temperature with amines, phosphines and arsines form compounds which are potential precursors to ceramic materials and semiconductors.
    Type: Grant
    Filed: June 2, 1989
    Date of Patent: March 26, 1991
    Assignee: The Research Foundation of State University of NY
    Inventor: Orville T. Beachley, Jr.
  • Patent number: 4997830
    Abstract: A pharmaceutical combination of Metronidazole and Amoxicillin for the treatment of periodontitis. Conventional therapeutic doses of both the Metronidazole and Amoxicillin given as a combination therapy has been unexpectedly found to effectively treat periodontitis.
    Type: Grant
    Filed: February 7, 1990
    Date of Patent: March 5, 1991
    Assignee: The Research Foundation of State University of New York
    Inventors: Arie J. van Winkelhoff, Edwin G. Winkel, Ronald J. Goene, Lars A. Christersson, Joseph J. Zambon, Robert J. Genco
  • Patent number: 4994376
    Abstract: The present invention relates to the detection of B. gingivalis by the specific ability of B. gingivalis to hydrolyze N-carbobenzoxy-glycyl-glycyl-L-arginine-B-napthylamide derivatives. The present invention also relates to the use of assay systems which inhibit serum amino peptidase and enhance the detection of the B. gingivalis N-CBz-Gly-Gly-Arg peptidase. The assay system inhibits the serum enzyme by the use of a serum aminopeptidase inhibitor which inhibits the activity of serum aminopeptidase to a greater extent that it inhibits the activity of B. gingivalis N-CBz-Gly-Gly-Arg peptidase. The assay system also increases the reliability of detection of the B. gingivalis enzyme by the use of enhancing materials which enhance the enzyme activity of B. gingivalis N-CBz-Gly-Gly-Arg peptidase to a greater extent than such materials enhance the enzyme activity of serum aminopeptidase.
    Type: Grant
    Filed: May 27, 1987
    Date of Patent: February 19, 1991
    Assignee: The Research Foundation of State University of NY
    Inventors: Joseph J. Zambon, Robert J. Gence
  • Patent number: 4966887
    Abstract: The present invention relates to a method of directly forming a thin, oriented layer, or film, of superconducting materials, or compositions suitably mixtures of Perovskite-type superconducting oxides, on a support base, or substrate, by the use of a laser assisted molecular beam epitaxy. The method steps generally comprise forming at least one target comprised of metallic precursors of a superconducting oxide composition and vaporizing at least a portion of the target using a vaporization laser beam to produce a vaporized precursor of an appropriate or desired entrained in a pulsed, rapidly flowing, gaseous atmosphere containing at least one gas reactive with said vaporized precursor composition to form a reacted precursor of a superconducting composition. The reacted precursor composition is then formed into a substantially singular, uniform molecular beam, and deposited on a substrate in the form of a thin layer.
    Type: Grant
    Filed: June 24, 1988
    Date of Patent: October 30, 1990
    Assignee: The Research Foundation of State University of NY
    Inventor: James F. Garvey
  • Patent number: 4946304
    Abstract: A weld joint between two structural elements out of different metallic carrier materials is described, in which at least approximately unmixed weld-joint-interface between the two elements made in such a manner, that on the one side of the interface only metal out of the one carrier material and on the other side only metal of the other carrier material is present. For example, the weld-joint-interface is made by an electron-beam welding. The surface of the weld joint can be enamelled and the welding of the two elements can be performed by a normal melt-welding method, in which welding material out of the metal of the respective carrier materials is laid on.
    Type: Grant
    Filed: May 13, 1988
    Date of Patent: August 7, 1990
    Assignee: The Pfaudler Companies, Inc.
    Inventor: Heinz Scharbach
  • Patent number: 4929510
    Abstract: A polymer article and a method for making the polymer article. The polymer article includes a hydrophobic polymer substrate and a block copolymer. The block copolymer has at least first and second blocks. The first block is more hydrophobic than the second block. The molecules of the block copolymer are secured into the surface of said substrate by means of the first block and at least a portion of the second block, outwardly extends from the surface of the substrate into the environment.The method for making the polymer article, comprising a block copolymer and a hydrophobic substrate, comprises the steps of: (a) forming a solution of a block copolymer and a solvent which will solubilize said block copolymer and swell said substrate. The block copolymer has at least a first and second block.
    Type: Grant
    Filed: April 29, 1988
    Date of Patent: May 29, 1990
    Assignee: State University of New York
    Inventors: Eli Ruckenstein, Dennis B. Chung
  • Patent number: 4810747
    Abstract: The present invention comprises a blend of two polyamide resins (first and second). The first resin comprises dibasic derivatives of fatty acids, monobasic acid and organic polyamines. The second resin comprises isophthalic acid, dibasic derivatives of fatty acids and organic polyamines. The combination of the first and second resins in proportional amounts results in a water dispersible polyamide blend which exhibits good blocking and release properties as well as improved water dispersibility and pigment wetting. This blend is useful in flexographic ink compositions as well as Cold Seal Release Lacquer formulations.
    Type: Grant
    Filed: February 5, 1988
    Date of Patent: March 7, 1989
    Assignee: NL Chemicals, Inc.
    Inventors: Walter K. Bornack, Jr., Keith R. McNally