Patents Represented by Attorney, Agent or Law Firm Ernest V. Linek
  • Patent number: 5213813
    Abstract: The use of pyridoxal-5'-phosphate as an in vitro anticoagulant agent which retains the platelet activity of stored whole blood or stored plasma for more than about six hours is disclosed.
    Type: Grant
    Filed: June 4, 1990
    Date of Patent: May 25, 1993
    Assignee: The University of Vermont
    Inventors: Elizabeth H. Kornecki, Vigal H. Ehrlich
  • Patent number: 5207992
    Abstract: A silicon single crystal pulling-up apparatus includes a silica glass crucible for accommodating a melted silicon material, a cylindrical member made of a carbon composite material which is composed of a carbon fiber wound round a cylinder, impregnated with a resin and carbonized, disposed on an upper end of a cylindrical portion of the crucible for accommodating the melted silicon in association with the cylindrical portion of the crucible, a wall thickness of the cylindrical member being not more than 3 mm, a rotational shaft for rotating the crucible, and a crucible support fixed to an upper end of the rotational shaft for supporting the crucible.
    Type: Grant
    Filed: April 22, 1991
    Date of Patent: May 4, 1993
    Assignee: Toshiba Ceramics Co., Ltd.
    Inventors: Shuitsu Matsuo, Kazuo Ito, Masayuki Saito
  • Patent number: 5203377
    Abstract: A method of repairing a pipeline and apparatus for use in such a method is disclosed where a sheet like repair material is set in position within the pipeline with the use of a settable substance, the repair material being carried into the pipeline on a core member (4) that carries an inflatable member, the inflatable member (1) extending axially along the core member (4) and at least partially around the core member (4) to define an annular or part annular enclosed space (9, 10) extending along the core member (4), means (8, 11) being provided to inflate or deflate the inflatable member when in position in the pipeline, the inflatable member further having an outer flexible surface portion fixed only at one axial end to the core member, the inflatable member (1) acting when inflated to press the repair material against the pipeline wall to be repaired with the inflatable member (1) being thereafter deflated with the apparatus being withdrawn from the pipeline in a direction whereby the outer wall portion of
    Type: Grant
    Filed: February 11, 1991
    Date of Patent: April 20, 1993
    Assignee: Barry Bros. Specialised Services Pty. Ltd.
    Inventor: David R. Harrington
  • Patent number: 5202417
    Abstract: Disclosed is a novel polypeptide whose N-terminus is EAQ and which is composed of 60 amino acids. The polypeptide is produced from human breast cancer cell MCF7, or human gastric cancer cell MKN-45 or KATO-III, which polypeptide has a isoelectric point of 4.
    Type: Grant
    Filed: August 21, 1989
    Date of Patent: April 13, 1993
    Assignee: Takeda Chemical Industries, Ltd.
    Inventor: Kyozo Hayashi
  • Patent number: 5193668
    Abstract: A touch-sensitive panel for outputting data corresponding to pressed positions on a touching plate included in the touch-sensitive panel and for sending the output data to a display device includes a plurality of first electrodes arranged on the touching plate, a plurality of second electrodes being opposed to the plurality of first electrodes and being capable of conducting to the plurality of first electrodes located at the pressed positions when the touching plate is pressed, a first connecting plate for connecting the plurality of first electrodes to the display device, a second connecting plate for connecting the plurality of second electrodes to the display device, an anisotropic electrically conductive bonding layer having a plurality of through holes and arranged on the first connecting plate, and a conductive layer including conductive particles, the conductive layer being laid between the plurality of first electrodes and the anisotropic electrically conductive bonding layer, the conductive particle
    Type: Grant
    Filed: April 22, 1991
    Date of Patent: March 16, 1993
    Assignee: Sharp Kabushiki Kaisha
    Inventors: Shunsei Fukuchi, Nobuhiro Kasai
  • Patent number: 5188601
    Abstract: Disclosed is a syringe assembly which greatly reduces the chances of an operator coming in contact with an infectious needle. The syringe assembly is initially provided with its needle retracted within its barrel, in a sterile and safe environment. When used, the needle is engaged by the plunger, and locked in place at the forward end of the syringe barrel. Before disposal, the needle is withdrawn back into the barrel, and the plunger is broken off. Thus, the disposed of syringe is incapable of being reused, and there is little or no danger of accidental punctures, because the needle is retained within the syringe barrel.
    Type: Grant
    Filed: November 6, 1991
    Date of Patent: February 23, 1993
    Inventor: Richard J. King
  • Patent number: 5175150
    Abstract: Disclosed are novel erythromycin derivatives, or salts thereof, represented by the following general formula: ##STR1## and processes for preparing the same. The erythromycin derivatives described above have an excellent effect of stimulating the gastrointestinal contractile motion and have low toxicity, and the preparations containing these compounds can be advantageously used as digestive tract contractile motion stimulants.
    Type: Grant
    Filed: December 17, 1990
    Date of Patent: December 29, 1992
    Assignee: Kitasato, Kenkyusho
    Inventors: Satoshi Omura, Zen Itoh
  • Patent number: 5173384
    Abstract: According to the present invention, there is provided a layered-type organic electrophotographic photoreceptor in which a charge generating layer containing organic charge generating material and a charge transporting layer containing organic charge transporting material are constructed on an electroconductive support, characterized in that a value n is not greater than 0.5 in the following equation (1):.eta.=.eta..sub.o E.sup.n (1)where .eta. represents a quantum yield as the whole photoreceptor, E represents an electric field and .eta..sub.o represents a constant, and that a film thickness of said charge transporting layer is not less than 30 .mu.m.
    Type: Grant
    Filed: April 8, 1992
    Date of Patent: December 22, 1992
    Assignee: Mitsubishi Kasei Corporation
    Inventor: Shigenori Otsuka
  • Patent number: 5169778
    Abstract: This invention relates to a substance Trehalostatin which is a white powder soluble in water but hardly or only slightly soluble in hexane, benzene, ethers and petroleum ether, shows no absorption maxima at 220 nm or above in its ultraviolet visible light absorption spectrum, is positive in Rydon-Smith reaction and negative in ninhydrin reaction, 3,6-dinitrophthalic acid reaction and Elson-Morgan reaction, has an Rf value of 0.37 in Merk Kieselgal 60 G.sub.254 thin layer chromatography using a 3:1:2 mixture of n-butanol, acetic acid and water as a developing solvent, and Rt of 11.0 minutes in YMC PA03 (0.7.times.27 cm) high performance liquid chromatography using 65% v/v acetonitrile (in H.sub.2 O) as a solvent at a flow rate of 1.0 ml/min, has a molecular weight of 366 and a specific rotatory power [.alpha.].sub.D of +115.degree., and presents an NMR spectrum described below:H-NMR/D.sub.2 O 3.3 (ppm), dd, 1H, 3.5 (ppm), m, 1H, 3.5 (ppm), t, 1H, 3.6 (ppm), d, 1H, 3.6 (ppm), d, 1H, 3.7 (ppm), d, 1H, 3.
    Type: Grant
    Filed: December 6, 1990
    Date of Patent: December 8, 1992
    Assignee: Sawao Murao
    Inventors: Sawao Murao, Takashi Shin
  • Patent number: 5165913
    Abstract: The present invention discloses dental floss containing surfactant and silicone preparations with added chemotherapeutic agents.
    Type: Grant
    Filed: August 29, 1991
    Date of Patent: November 24, 1992
    Inventors: Ira Hill, Robert D. White
  • Patent number: 5159818
    Abstract: An apparatus for preparing a semi-frozen confection of the present invention has a freezing cylinder for main ingredient of the semi-frozen confection, and a syrup refrigerating cylinder installed in the vicinity of both a semi-frozen confection dispensing conduit and the freezing cylinder. Accordingly, when preparing a semi-frozen confection composed of, e.g., ice cream and syrup to be served in a cone, rise in the temperature of the ice cream caused by the syrup may be restrained, thereby enabling the semi-frozen confection produced to retain its shape. The apparatus further has a microcomputer for controlling the rotating speed of at least one of the mixers respectively housed in the freezing cylinder and in the syrup refrigerating cylinder. This permits the proportion of, e.g., the ice cream and syrup composing the semi-frozen confection to be varied as desired.
    Type: Grant
    Filed: March 4, 1991
    Date of Patent: November 3, 1992
    Assignee: Hideo Asada
    Inventors: Ryoukichi Etou, Kinji Hashizume, Mitsuo Ikeda, Hideo Asada
  • Patent number: 5149804
    Abstract: Ecteinascidins 722 and 736 (Et's 722 and 736) have been isolated from the Caribbean tunicate Ecteinascidia turbinata and their structures have been assigned as tetrahydro-.beta.-carboline-substituted bis(tetrahydro- isoquinolines) related to the previously reported Et's 729 and 743. Et's 722 and 736 protect mice in vivo at very low concentrations against P388 lymphoma, B16 melanoma, and Lewis lung carcinoma.
    Type: Grant
    Filed: November 30, 1990
    Date of Patent: September 22, 1992
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Kenneth Rinehart, Ryuichi Sakai
  • Patent number: 5142391
    Abstract: A liquid-crystal display device of optical writing type includes a first transparent substrate, a first transparent electrode layer formed on the first transparent substrate, a photoconductive layer formed on the first transparent electrode layer, a light-absorbing layer composed of an organic film, the light-absorbing layer formed on the photoconductive layer, a dielectric layer formed on the light-absorbing layer, a second transparent substrate, a second transparent electrode layer formed on the second transparent substrate, and a liquid-crystal layer disposed between the second transparent electrode layer and the dielectric layer.
    Type: Grant
    Filed: April 22, 1991
    Date of Patent: August 25, 1992
    Assignee: Sharp Kabushiki Kaisha
    Inventors: Sayuri Fujiwara, Naofumi Kimura
  • Patent number: 5142026
    Abstract: Disclosed is a novel recombinant human lyphotoxin (LT) mutein which combines with an antibody at an inactive site of an LT molecule and liberates the LT molecule easily from the antibody after incorporation of the mutein into tumor cells.The recombinant human LT mutein is prepared by introducing a polydeoxyribonucleic acid containing a nucleotide sequence coding for the particular amino acid sequence into a replicable vector, transforming a microorganism or a cell with the recombinant DNA thus obtained, and cultivating the resulting transformant to express genetic information of the polydeoxyribonucleic acid.The recombinant human LT mutein is useful for tumor-selective carcinostatics, and effective for increasing the actively of LT and reducing the side effects thereof.
    Type: Grant
    Filed: May 3, 1989
    Date of Patent: August 25, 1992
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Susumu Iwasa, Hiroko Tada
  • Patent number: 5137870
    Abstract: Novel antibiotics didemnins A, B and C (didemnins), and nordidemnins A, B and C (nordidemnins) which can be obtained from a marine organism. These antibiotics are active against a variety of DNA and RNA viruses; thus, they can be used in various environments to control or eradicate these viruses. Further, these antibiotics can be used to treat animals and humans hosting a neoplastic disease.
    Type: Grant
    Filed: February 20, 1990
    Date of Patent: August 11, 1992
    Assignee: The Board of Trustees of the University of Illinois
    Inventor: Kenneth L. Rinehart
  • Patent number: 5130222
    Abstract: An electrophotographic photoreceptor having an electrically conductive substrate and a photosensitive layer formed thereon, the photosensitive layer comprising a charge-generating agent, an organic charge-transporting agent and an anti-oxidant having the general formula: ##STR1## wherein R.sup.1 and R.sup.2 are independently alkyl groups, is disclosed herein. The electrophotographic photoreceptor according to this invention has an improved durability in repeated copying operations and therefore a prolonged life.
    Type: Grant
    Filed: June 19, 1990
    Date of Patent: July 14, 1992
    Assignee: Mitsubishi Kasei Corporation
    Inventors: Shigenori Otsuka, Mamoru Nozomi
  • Patent number: 5121925
    Abstract: The present invention relates to a golf swing training and muscle exercising apparatus (or "club") which includes a shaft having the non-grip end thereof bent at about 22.05 degrees and on which rotatable off-center swing weights are mounted which enables a user to simulate the movements of a proper golf swing and which also exercises the muscles of the golfer making such a swing. Two embodiments are provided in this invention, each based upon the same design principle. One embodiment is intended for use outdoors, e.g., at the driving range or even on the course. The other embodiment, is preferably intended for use indoors, but can be used anywhere.
    Type: Grant
    Filed: November 1, 1991
    Date of Patent: June 16, 1992
    Inventor: Frank Blundo
  • Patent number: 5120715
    Abstract: Disclosed is a method for purifying a fibroblast growth factor (FGF) protein with use of a crosslinked polysaccharide sulfate. The FGF protein is preferable a mutein, in which at least one human basic FGF-constituent amino acid is substituted by at least one different amino acid. The crosslinked polysaccharide sulfate is preferably a crosslinked cellulose sulfate, a crosslinked agarose sulfate or a crosslinked dextran sulfate. According to the present invention, FGF can be highly purified on a commercial scale, and therefore preparations containing the FGF protein can be advantageously formulated.
    Type: Grant
    Filed: November 30, 1989
    Date of Patent: June 9, 1992
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Koichi Kato, Kenji Kawahara, Tomoko Kajio
  • Patent number: 5110423
    Abstract: This invention relates to alkyl and alkanol sulfonic acid plating baths and to methods for plating tin and tin-lead alloys. It also relates to low foaming wetting systems based on low to moderate foaming surfactants and soluble, non-silicon containing defoamers, and to low volatility brightener systems.
    Type: Grant
    Filed: May 25, 1990
    Date of Patent: May 5, 1992
    Assignee: Technic Inc.
    Inventors: John L. Little, Philip W. Schultz, Harry Kroll
  • Patent number: 5103524
    Abstract: Apparatus for cleaning tubes in an array of such tubes (162, 175) such as heat exchanger or condenser units that will allow such cleaning action to be undertaken without removing the unit containing the array of tubes from normal service, the apparatus being adapted to be mounted in a head space zone of the unit and comprising a launcher (159, 192) movable on the head space zone to align with the tubes to be cleaned, the launcher being arranged to receive sequentially projectiles (1) from a projectile supply path (11) and to transfer same in a sealed manner to a pressurized fluid delivery path (89, 39) passing through the launcher (159, 192) so that the projectile is aligned with a tube to be cleaned.
    Type: Grant
    Filed: November 16, 1990
    Date of Patent: April 14, 1992
    Assignee: Barry Bros. Specialised Services Pty. Ltd.
    Inventor: Robert W. Vowles