Abstract: The present invention relates to unique interdental delivery devices, other than dental floss, which are suitable for cleaning, massaging, and/or treating surfaces of teeth and gums including interproximal and subgingival areas; wherein these devices contain ULTRAMULSION.TM. dispersions of high viscosity silicones dispersed in surfactants, these dispersions are released into the oral cavity from these devices during use wherein the dispersed silicone:a. is insoluble in the surfactant and oriented so as to form coatings in the oral cavity with enhanced substantivity,b. functions as a reservoir for various lipid soluble and/or liquid dispersible ingredients to be released onto oral cavity surfaces, andc. has a particle size from between about 0.1 and about 10 microns with from between about 80% and about 95% of the particles within this range.

Abstract: Three cytotoxic peptides, the known compound Jaspamide and two new peptides, hemiasterlin (Compound 2) and geodiamolide TA (Compound 3), have been isolated from the sponge Hemiasterella minor. The structures of the three were determined by interpreting the NMR and mass spectra. Hemiasterlin (Compound 2) is a novel linear tripeptide embodying two unique, new natural amino acids and geodiamolide TA (Compound 3) is a newly discovered higher homolog of geodiamolides A-F.

Abstract: Ecteinascidins (Et's), isolated from the Caribbean tunicate Ecteinascidia turbinata, protect mice in vivo against P388 lymphoma, B16 melanoma, M5076 ovarian sarcoma, Lewis lung carcinoma, and the LX-1 human lung and MX-1 human mammary carcinoma zenografts.

Abstract: The present invention is a reagent which, when added as a conditioning solution to samples containing calcium and magnesium, selectively converts the calcium into a complex which does not interfere with magnesium ISEs, and thus allows accurate magnesium determinations by ISE in a wide variety of samples. The conditioning solution also eliminates strontium and barium interferences by the same mechanism, but these are of secondary importance because they occur in samples less frequently and because they interfere less severely. Also, the formulation of the reagent was optimized solely in order to eliminate calcium interference and its ability to remove strontium and barium interferences was surprisingly fortuitous.

Abstract: The present invention relates to various oral care products containing, stable, dispersions of certain high viscosity silicones in certain surfactants; wherein:a. the dispersed silicones, which are insoluble in said surfactant, are oriented by the surfactant such that when dispersed in water they are particularly adept at forming oriented, coatings on surfaces of the mouth with enhanced substantivity, andb. the particle size of the dispersed silicone is from between about 0.1 and about 10 microns, with a particle size distribution such that from between about 80 and 95% of the dispersed silicone is within this particle size range. These stable dispersions are described as ULTRAMULSIONS, which, together with their physical properties, when contained in oral care products, provide these oral care products with enhanced substantivity to mouth surfaces, where the non continuous silicone phase functions as a reservoir for various active ingredients contained therein.

Abstract: Disclosed is a tool with cutting surfaces on the sides, end and tip that is inserted into a handpiece or milling machine. It is used according to a specific technique disclosed herein to mill precision surfaces in dental prostheses that are retained by screws to dental implants, abutments or replicas. The invention mills all types of dental implant prostheses that use a screw for retention. The milling tool of this invention allows the screw to pass through the screw access opening in the prosthesis and fit flush against the screw seat in the prosthesis, leaving space between the axial surfaces of the head of the screw and the screw access channel of the restoration. It also mills the small opening through the prosthesis through which the shank of the screw passes, so there is no contact between the prosthesis and the shank of the screw.

Abstract: The present invention relates to various oral care rinses containing, stable, dispersions of certain high viscosity silicones in certain surfactants; wherein:a. the dispersed silicones, which are insoluble in said surfactant, are oriented by the surfactant such that when dispersed in water they are particularly adept at forming oriented, coatings on surfaces of the mouth with enhanced substantivity, andb. the particle size of the dispersed silicone is from between about 0.1 and about 10 microns, with a particle size distribution such that from between about 80 and 95% of the dispersed silicone is within this particle size range. These stable dispersions are described as ULTRAMULSION.TM.

Abstract: A radome for providing a relatively wide-band operation which in a preferred embodiment uses at least a pair of panel means mounted adjacent each other, each having a plurality of discontinuous conductive elements applied to a selected surface thereof in an array of parallel paths. The discontinuous elements in each path of the array are interconnected by diode means which can be biased in a non-conductive direction during a first transmit mode and in a conductive direction during a second non-transmit mode. The panels are separated by a distance which is substantially equal to one quarter wave length (.lambda..sub.s /4) at a selected frequency within the wide pass-band of electromagnetic energy which is to be transmitted.

Abstract: Azaanthracene-triones of the formula: ##STR1## (in which: R.sup.1, R.sup.2, R.sup.4 and R.sup.5 are the same or are different and each is a hydrogen atom or a lower alkyl group;R.sup.3 is a hydrogen atom, a lower alkyl group, a phenyl group or an amino-substituted phenyl group; andX is a --CH--, .dbd.N-- or --NH--, whereby the ring containing the group X is a benzene, pyridine or dihydropyridene ring)have antitumoral activity.

Abstract: A method for analyzing spinal characteristics of a patient believed to have one or more spinal abnormalities in which vertebral body rotations of the patient are determined for a plurality of spinal vertebrae and are graphically displayed along with vertebral body rotations of a normal person having no spinal abnormalities so that such displays can be readily compared to determine the locations of a patient's spinal abnormalities. Similar graphical displays of the differences in the relative rotational relationship of each vertebra and its superior neighboring vertebra can be provided for a patient and compared with graphical displays thereof for a normal person to identify locations of abrupt positional alignment changes representing spinal abnormalities Of the patient.

Abstract: A container top including cover with rotatable member, the rotatable member supporting a sealing member for the opening in the cover, the cover having camming member for engaging said rotatable member as the rotatable member is rotated from a sealing to an open position.

Abstract: A "shutter" type structure for transmitting electromagnetic energy within a selected frequency range and preventing the transmission of such energy outside such range during a first open shutter mode of operation and for preventing the transmission of any electromagnetic energy during a second closed shutter mode of operation. The structure includes an insulative member having an array of symmetrical conductive elements on at least one surface, such elements being interconnected by diode elements in both vertical and horizontal directions. The diodes are placed in their conductive states during the first mode of operation and in their non-conductive states during the second mode of operation.

Abstract: A structure for selectively transmitting electromagnetic energy over a selected frequency range during a first operating mode and for substantially preventing the transmission of electromagnetic energy at any frequency during a second operating mode either by absorption or by reflection of such energy. The structure includes at least one shutter means comprising continuous and discontinuous elements and diode means interconnecting the discontinuous portions of the discontinuous element. The diode means are biased in a non-conductive direction during the first operating mode and are biased in a conductive direction during the second operating mode. The structure can further include filter means which include continuous and discontinuous elements arranged so as to be resonant over the selective frequency range during both operating modes.

Abstract: The invention relates to a method for the treatment or prophylaxis of psychosis, depression, hypertension, or anxiety in an animal by administering an effective amount of an N,N'-disubstituted guanidine or 2-iminoimadazolidine having an affinity for the sigma receptor. The invention also relates to the novel guanidines of the invention as well as pharmaceutical compositions thereof.