Abstract: Stereospecific synthesis of the racemic threo isomers of 2-nitro-1-phenylpropanols by reacting a benzaldehyde derivative with nitroalkane in the presence of a tertiary amine and reducing 2-nitro-1-phenylpropanols with, for example, lithium aluminum hydride to 2-amino-1-phenylpropanols is described. Also described are phase transfer resolution of racemic mixtures of 2-amino-1-phenylpropanol and its derivatives into their optically pure isomers by reacting a racemic mixture with the mono alkali metal salt of a tartaric acid ester in a two phase system of a hydrocarbon and water. The specification further describes therapeutically useful optically pure isomers of threo-2-amino-1-(dialkoxy or alkoxy) phenylpropanols and acid addition salts thereof.

Abstract: A substantially flexible, dry matrix with antimicrobial properties is made from a matrix comprising natural or synthetic, woven, non-woven or knitted fibers, said matrix having been uniformly coated with an amount of a non-aqueous treatment solution sufficient to allow said matrix to retain its substantially dry characteristics. In a preferred embodiment, said non-aqueous treatment solution has between about 70% and 99% of at least one glycol compound, between about 1% and 15% of a PVP-iodine and optionally between about 0 and 15% of a non-ionic surfactant.Also, skin is treated to prevent disease, such as the disinfecting of teats on dairy cows during milking, by wiping the skin with the article.

Abstract: The present invention pertains to the field of pain management in medicine. Methods for treating reflex sympathetic dystrophy (including causalgia) are provided, in which a haloalkylamine a adrenergic blocking agent and a local anesthetic are administered to the affected limb by intravenous regional block. Formulations which can be used in these methods are also provided. In a preferred embodiment, phenoxybenzamine and either lidocaine or procaine are administered to the affected limb using a Bier block procedure.

Abstract: Disclosed is an impeller made from titanium or a titanium alloy. Desirably, the titanium or titanium alloy is cast into the impeller.

Abstract: A stripping and transfer assembly for a food product interleaver apparatus includes a conveyor having an endless-type conveying surface formed with raised ribs spaced apart in parallel, a comb member having a plurality of teeth inserted between the raised ribs at the downstream end of the conveyor and curved surfaces for lifting off food product units from the conveyor, and a rotatable transfer wheel positioned above the comb member having a flexible outer annular contact surface for lightly engaging food product units lifted off by the comb member and moving them to a drop-off point onto a carrier sheet. Preferably, the transfer wheel is made of an elastic material and has radial spokes extending at an inclined angle to the outer annular contact surface for promoting radial deformation of the transfer wheel. The relative positions of the comb member and transfer wheel can be adjusted optimally.

Abstract: A drawer stop device, for use in combination with a sliding drawer mounted in a cabinet behind a front door vertically hinged to one lateral side of the cabinet, has a mounting portion which is mounted to a portion adjacent to a vertical front edge of the drawer, a bearing portion having a bearing flange which projects perpendicularly from the mounting portion, and a roller element rotatably mounted on an end of the bearing flange such that it can make rolling contact with the door ahead of the vertical front edge when the drawer is slid out from the cabinet. This prevents the front edges of the drawer from bumping against and scratching the inside surface of the door.

Abstract: An improved process for the preparation and fabrication of horseshoes whereby pure titanium or titanium alloys are processed with the exclusion of contaminating gases such as oxygen, nitrogen and hydrogen. The titanium horseshoes have many advantages over the present state of art such as light weight, higher tensile strength, flexibility, wearing resistance, abrasion resistance, hypoallergenic, workability, formability, friction-free, physiologically inert, and are easily formed and shaped into the desired configuration.

Abstract: Compositions and method for treating conditions in humans associated with symptoms of unspecified retarded maturation due to chromosomal abnormalities cerebral atrophy, Huntington's Chorea, Alzheimer's disease and the like wherein the composition comprises a) at least one of haloperidol, imipramine and trifluoperazine, b) gamma butyric acid, c) phenylalamine, d) an antioxidant, e) folic acid, f) nicotinamide or its salt and g) a lithium salt. The composition can additionally contain a benzodiazepine and is administered orally.

Abstract: Microparticulate carrier materials for a large and varied group of pharmaceutical and cosmetic agents are disclosed. Microdispersions of such carrier materials charged with at least one isomer or derivative of 2-amino-1-phenylpropanol are also described. The microdispersions can be formulated for oral, parenteral, topical, inhalation and suppository administration. The formulations have varied uses depending on the pharmaceutical and or cosmetic agent utilized. The microparticles are suitably charged particles of silica, alumina, boron, charcoal and the like and have a particle size of about 3 to about 250 .mu.m. The pharmaceutical and cosmetic active materials complex with the microparticles. The liquid carrier for the microparticles include water, propylene glycol, alcohols such as methanol, ethanol and propanols, and dimethyl sulfoxide.

Abstract: A tactile warning surface has an array of tactile elements made of a composite material formed on the surface of an existing substrate. The preferred composite material is a mixture of a dry powder aggregate and a liquid SBR latex. The tactile elements are in the form of truncated cones or flattened domes having a height of about 0.20 inch and a diameter of about 1.0 inch. A method for installing the tactile warning surface includes the steps of placing a mold sheet having an array of mold apertures with shapes corresponding to the tactile elements over the substrate area, injecting the composite material in a semi-liquid state under pressure into the apertures of the mold sheet, allowing the injected composite material to cure and harden, then removing the mold sheet. For increased durability in traffic-bearing applications, a pigment/aggregate mixture can be applied as a coating over the tactile elements and substrate area.

Abstract: A cup holder sleeve is formed in pre-assembled, flat-folded form by diecutting a flat, elongated band from blank stock material so as to have top and bottom arcuate edges concentric to and in parallel with each other, fold lines scored into the band at spaced apart positions tapering toward each other, and side edges at opposite ends of the band. The opposite ends are folded flat at the fold lines so that the side edges overlap each other and are glued together at their overlapping surfaces. The flat-folded form allows for compact storage. The pre-assembled sleeve can be readied for use simply by squeezing on the outside surfaces so as to bow out the flat-folded band into an annular tapered sleeve with opened top and bottom ends for inserting a cup therein. In a preferred embodiment, the sleeve is made of paperboard material and is printed with graphics and embossed with a pattern to provide an insulating layer as well as better gripping of the sides of the cup.

Abstract: A chewing gum composition for whitening teeth comprising a water insoluble gum base in admixture with a plasticizer, a flavorant, sweetener, filler, texturizer, color, stabilizer, surface active agent and the like, some of the foregoing being optional, and a safe and effective whitening amount of a water soluble alkali metal percarbonate, a safe and effective amount of neem oil, sodium bicarbonate and parsley extract.

Abstract: A multi-purpose landscaping device for use with as hand-held rotary power tool such as an electric drill includes a shaft adaptable at one end for removable and operative connection to such a power tool, and a rotatable implement removably attached to the other end of the shaft, so that replacement of the rotatable implement is possible without replacement of the shaft. The rotatable implement is selected from the group consisting of a greenery cutter, a blower, a pruner, a soil augur and a weed extractor.

Abstract: Non-metallic microparticulate carrier materials for a large and varied group of pharmaceutical and cosmetic agents are disclosed. Microdispersions of such carrier materials charged with at least one such pharmaceutical and/or cosmetic agent are also described. The microdispersions can be formulated for oral, parenteral, topical, inhalation and suppository administration. The formulations have varied uses depending on the pharmaceutical and or cosmetic agent utilized such as for combating microbial, fungal, yeast, viral and the like infections, treating acne, Herpes, burns, dermatoses caused by poisonous plants and irritants, reduction of wrinkles, moisturizing skin, etc. The microparticles are suitably charged particles of silica, alumina, boron, charcoal and the like and have a particle size of about 3 to about 250 .mu.m. The pharmaceutical and cosmetic active materials, which include ozone, vitamins, hormones, steroids, minerals humectants, etc., complex with the microparticles.

Abstract: Wet towelette dispensers are provided which include a roll of moistened, flushable towelettes, each of which is readily separable along perforated lines from a remaining portion of the towelette roll. The towelettes are designed to have a high enough wet strength to be useful for hygienic applications. The roll is disposed in a sealable housing which has a slotted opening therein for permitting the removal of one more of the towelettes from the dispenser in a manner similar to the way dry toilet paper is typically dispensed.

Abstract: A manually-written, machine-readable code system employs the application of indicia to an article, such as a mail envelope or package, having a number of rows/columns of blank spaces in a predetermined code field which are manually marked or darkened corresponding to a destination or identifying code for the article. The indicia may have been applied previously, as in the form of a preprinted envelope. The darkened spaces are machine-readable and convertible to a numeric code that can be used by an automated machinery to generate appropriate control signals for controlling its functions. The system is particularly applicable for automated sorting of mail according to postal area (Zip) codes. The indicia is readily applied to an envelope by preprinting or by using a rubber stamp or an adhesive label.

Abstract: Formulations are provided for the treatment of patients suffering from disorders that have in common the appearance of muscular hypotonia as a symptom. These disorders include Alzheimer's type diseases, atrophy of the brain, atrophy of the cerebellum, Fragile X syndrome, mental retardation of unknown causes, multiple anomalies in the chromosomes, deletions in one or more chromosome, and fragility in a chromosome other than the X chromosome. The formulations of the invention contain therapeutically effective amounts of gamma amino butyric acid (GABA), an anti-oxidant (such as ascorbic acid and/or vitamin E), folic acid, nicotinamide, and a lithium salt, all in a pharmaceutically acceptable excipient. Methods for the treatment of these disorders by the administration of such formulations are also provided.