Abstract: Novel MCP-1 splice variant polypeptides and polynucleotides encoding same are provided. Also provided are pharmaceutical compositions comprising the splice variant polypeptides and polynucleotides, vectors and host cells comprising same. The compositions of the present invention are useful to treat various MCP-1 related disorders as well as for diagnosing, determining predisposition and/or prognosis of various disorders.

Abstract: The claimed invention involves a novel composition of matter comprising a mixture of Fe—Mo Intermetallic and copper oxide. A novel composition of matter of Fe—Mo Intermetallic, copper oxide and calcium carbonate is also claimed. The claimed invention also involves a novel friction lining additive comprising Fe—Mo Intermetallic and copper oxide for improved braking effectiveness. Fe—Mo Intermetallic, copper oxide and calcium carbonate may also be used as a friction lining additive according to the present invention. The claimed invention also includes a novel motor brush comprising Fe—Mo Intermetallic and copper oxide for improved wear. Fe—Mo Intermetallic, copper oxide and calcium carbonate may also be used as a motor brush additive according to the present invention.

Abstract: Efficient fuel combustion catalyst delivery device and method are provided. A fuel combustion catalyst delivery device includes a storage vessel that contains a liquid. The liquid includes one or more catalytic materials. The storage vessel is attached to a nebulizer that can convert the liquid to an aerosol to be delivered into an air intake of a combustion zone. The aerosol can accelerate fuel combustion. The storage vessel and the nebulizer are made from materials suitable to be exposed to the liquid and the aerosol. The storage vessel and the nebulizer are also suitable to be placed in proximity to the combustion zone such as an engine compartment so that the aerosol can be delivered into the air intake of the combustion zone easily and effectively. The surfaces of the delivery device exposed to the liquid or the aerosol may be made of corrosion-resistant or inert materials if the liquid is acidic.

Abstract: The invention relates to pharmaceutical compositions and methods of treating inflammatory-related diseases associated with pro-inflammatory cytokine expression and/or reduced expression of anti-inflammatory cytokines. The method typically comprises administration of one or more compounds selected from isoindigo, indigo, indirubin, or derivatives thereof, such as, Meisoindigo and NATURA. Preferably the pharmaceutical composition comprises one or more compounds selected from isoindigo, indigo, indirubin, or derivatives thereof, an anti-inflammatory agent, and a pharmaceutically acceptable carrier.

Abstract: Apparatus for producing silver nano-particle material. The apparatus includes a furnace containing a crucible for vaporizing a precursor material, as well as, a conduit disposed in perpendicular to the crucible. An inlet end of the conduit is open to the mixing region created between the conduit and the crucible. A process gas supply is also operatively associated with the mixing region.

Abstract: Apparatus for producing nano-particles according to the present invention may comprise a furnace defining a vapor region therein. A precipitation conduit having an inlet end and an outlet end is positioned with respect to the furnace so that the inlet end is open to the vapor region. A quench fluid supply apparatus supplies quench fluid in a gas state and quench fluid in a liquid state. A quench fluid port positioned within the precipitation conduit is fluidically connected to the quench fluid supply apparatus so that an inlet to the quench fluid port receives quench fluid in the gas state and quench fluid in the liquid state. The quench fluid port provides a quench fluid stream to the precipitation conduit to precipitate nano-particles within the precipitation conduit. A product collection apparatus connected to the outlet end of the precipitation conduit collects the nano-particles produced within the precipitation conduit.

Abstract: Gaseous fluid production apparatus according to one embodiment of the invention includes a fluid container containing fluid substantially in the liquid state. A first fluid line is connected to the fluid container so that it receives from the fluid container a first fluid stream substantially in the liquid state. A gas generator is also connected to the fluid container so that it receives from the fluid container a second fluid stream substantially in the liquid state. A product discharge manifold is connected to the gas generator and to the first fluid line. A controller means is operatively associated with the first fluid line and the product discharge manifold for controlling at least one parameter of the first fluid stream. A second controller means is operatively associated with the gas generator and the product discharge manifold for controlling at least one parameter of the second fluid stream.

Abstract: The present invention is directed to a specialized method of treating a severe diabetic ulcer that penetrates the subcutaneous fat layer of a patient. The method comprises the steps of: administering a treatment session to a diabetic patient having a severe diabetic ulcer, the treatment session comprising at least three pulsed electromagnetic fields (PEMF) applications, PEMF applications 1, 2, and 3, and at least two intermittent compression therapy (ICT) applications. The PEMF application and ICT therapy settings address specific factors that are necessary to induce healing of the diabetic ulcer and prevent amputation. In a preferred embodiment, the treatment session further comprises the step of applying a dressing having a silver and/or honey anti-infection composition thereon to the ulcer area to impede microbial growth in the ulcer area. In another embodiment, the method includes the step of applying ultrasound to the ulcer area for a time sufficient to inhibit microbial growth.

Abstract: Aqueous polishing slurries for chemical-mechanical polishing are effective for polishing copper at high polish rates. The aqueous slurries according to the present invention may include soluble salts of molybdenum dissolved in an oxidizing agent and molybdic acid dissolved in an oxidizing agent. Methods for polishing copper by chemical-mechanical planarization include polishing copper with low pressures using a polishing pad and a aqueous slurries including soluble salts of molybdenum dissolved in an oxidizing agent and molybdic acid dissolved in an oxidizing agent, particles of MoO3 dissolved in an oxidizing agent, and particles of MoO2 dissolved in an oxidizing agent.

Abstract: Densified molybdenum metal powder and method for producing same. Densified molybdenum powder has substantially generally spherical particles, surface area to mass ratio of no more than about 0.5 m2/g as determined by BET analysis, and a flowability greater than about 32 s/50g as determined by a Hall Flowmeter. A method for producing densified molybdenum metal powder includes providing a supply of precursor material of molybdenum metal powder particles reduced from ammonium molybdate; providing a supply of reducing gas; densifying the precursor material in the presence of the reducing gas; and producing the densified molybdenum metal powder.