Abstract: Novel N-(substituted-phenyl)-5-(2,5-dimethylphenoxy)-2,2-dimethylpentanamides which are useful in preventing the intestinal absorption of cholesterol, as well as novel pharmaceutical compositions and methods of use, as well as processes for their manufacture are herein described.
Abstract: A composition for the transmembranal, including transdermal administration of a pharmaceutical preparation comprising medical grade dimethylsiloxane, a catalyst capable of forming an elastomer, a permeation enhancer and a biologically active material, as well as a device for administering the aforementioned compositions and also a method for administering transdermally to a mammal an effective amount of the aforementioned compositions is herein described.
Type:
Grant
Filed:
September 8, 1987
Date of Patent:
March 21, 1989
Assignee:
Warner-Lambert Company
Inventors:
Suk-Zu Song, Zahra A. Rashidbaigi, Surendra C. Mehta, Russell U. Nesbitt, Mahdi B. Fawzi