Patents Represented by Attorney Heller Ehrman White & McAuliffe

Find this attorney in the Justia Lawyer Directory

  • Method and apparatus for micro-machining of articles that include polymeric materials
    Patent number: 6734387
    Abstract: A micro-machining apparatus includes a mode-locked, infrared laser system with a high reflector and an output coupler that define an oscillator cavity which produces an output beam. A gain medium and a mode locking device are positioned in the oscillator cavity. A diode pump source produces a pump beam that is incident on the gain medium. A second harmonic generator is coupled to the oscillator cavity. A third harmonic generator is coupled to the second harmonic generator and produces a UV output beam. An output beam directing apparatus directs the output beam to a polymeric surface of an article. At least a portion of the polymeric material is micro-machined by the output beam.
    Type: Grant
    Filed: April 1, 2002
    Date of Patent: May 11, 2004
    Assignee: Spectra Physics Lasers, Inc.
    Inventors: James D. Kafka, Mingwei Li
  • Systems and methods for packet filtering
    Patent number: 6735179
    Abstract: Systems and methods are described for converting priority based rules into isomorphic longest match rules. Rules for packet processing may be presented to a networking device in priority order, through an interface such as a Command Line Interface (CLI) or from networking applications which may reside on the networking device. The networking device may include hardware and/or software layers for accelerating packet processing; a forwarding layer may include hardware and/or software designed to perform longest match searches on packets. Prioritized rules may be converted into a data structure for the forwarding layer, so that a longest match search performed by the forwarding layer on the data structure is equivalent to a priority order search on the prioritized rules.
    Type: Grant
    Filed: February 14, 2002
    Date of Patent: May 11, 2004
    Assignee: Bivio Networks, Inc.
    Inventor: Yakov Teplitsky
  • Balanced distortion reduction circuit
    Patent number: 6734726
    Abstract: A method and apparatus for utilizing the distortion generated within a portion of a balanced amplifier to cancel the distortion generated within the whole balanced amplifier. Samples of the signal and distortion from part of the balanced amplifier are combined with a reference signal such that the two signals destructively combine leaving the distortion from the sampled part of the balanced amplifier. The gain and phase of the distortion is then adjusted so that when it is coupled into the input of the other part of the balanced amplifier the distortion generated by both parts of the balanced amplifier are cancelled.
    Type: Grant
    Filed: June 27, 2002
    Date of Patent: May 11, 2004
    Assignee: Remec, Inc.
    Inventor: Mark Billsberry
  • Devices with optical gain in silicon
    Patent number: 6734453
    Abstract: A photonic device includes a silicon semiconductor based superlattice. The superlattice has a plurality of layers that form a plurality of repeating units. At least one of the layers in the repeating unit is an optically active layer with at least one species of rare earth ion.
    Type: Grant
    Filed: August 7, 2001
    Date of Patent: May 11, 2004
    Assignee: Translucent Photonics, Inc.
    Inventors: Petar B. Atanackovic, Larry R. Marshall
  • Method and apparatus for controlling sub-clinical laser procedures with intra-operative monitoring of electrophysiological changes
    Patent number: 6733490
    Abstract: A method of monitoring and controlling the sub-threshold laser treatment of a patient's retina. Sensors are located on a patient to measure focal electroretinograms (FERG). A stimulating beam is delivered onto the patient's retina. A pre-treatment FERG signal is collected. Treatment FERG signals are collected while treating the retina with a sub-threshold laser treatment. A difference is determined between the pre-treatment and treatment FERG signals. The difference is used to control the termination of the treatment.
    Type: Grant
    Filed: April 12, 2002
    Date of Patent: May 11, 2004
    Assignee: Iridex Corporation
    Inventors: Benedetto Falsini, Giorgio Dorin
  • Determination of endometrial receptivity toward embryo implantation
    Patent number: 6733979
    Abstract: Methods for detecting receptivity of mammalian endometrium to embryo implantation comprising obtaining a sample of the endometrium, contacting the endometrium with a monoclonal antibody for &bgr;3 and detecting &bgr;3 in the endometrium. The invention also provides for methods of diagnosing infertility in a mammal and methods of detecting the window of embryo implantation in endometrium. Methods of in vitro fertilization, methods of preventing embryo implantation and a method of monitoring endometrial maturation are also within the scope of the present invention. The present invention is also directed to contraceptives. Diagnostic kits useful in the practice of the methods of the invention are also provided.
    Type: Grant
    Filed: September 8, 1998
    Date of Patent: May 11, 2004
    Assignee: The Trustees of the University of Pennsylvania
    Inventor: Bruce Lessey
  • Upper audio range hearing apparatus and method
    Patent number: 6731769
    Abstract: A system and method upper auditory frequency range hearing. A speech signal is filtered, and then modulated to an upper auditory frequency range. The modulated signal is then provided to a transducer, which causes a vibration in the ear canal, the head or the neck of a user, which is received in an inner ear of the user. That vibration is translated as a signal to the brain, which interprets that signal as intelligible speech.
    Type: Grant
    Filed: October 14, 1999
    Date of Patent: May 4, 2004
    Assignee: Sound Techniques Systems LLC
    Inventor: Martin L. Lenhardt
  • Drying method, drying device, and drying machine
    Patent number: 6725563
    Abstract: A drying method, a drying device, and a drying machine, capable of remarkably reducing a drying time by assigning the standby time for an article to be dried to a preliminary drying time in drying, wherein hot air is supplied to the drying machine so as to dry the article to be dried and, at the same time, hot air exhausted from the drying machine is led into a preliminary drying machine so as to preliminarily dry the article to be dried before drying, and then the article to be dried contained in the preliminary drying machine is fed to the drying machine for drying.
    Type: Grant
    Filed: December 4, 2001
    Date of Patent: April 27, 2004
    Assignee: Hakko Co., Ltd.
    Inventors: Yoshihisa Miyamoto, Shigemitsu Hayashi
  • IR MALDI mass spectrometry of nucleic acids using liquid matrices
    Patent number: 6723564
    Abstract: Mass spectrometry of large nucleic acids by infrared Matrix-Assisted Laser Desorption/Ionization (MALDI) using a liquid matrix is reported.
    Type: Grant
    Filed: May 7, 1998
    Date of Patent: April 20, 2004
    Assignee: Sequenom, Inc.
    Inventor: Franz Hillenkamp
  • Delivery of a composition to the liver by utilizing the portal vein
    Patent number: 6722370
    Abstract: In general, the invention features methods for delivering a composition to the liver in a non-surgical, percutaneous approach by utilizing the portal vein. Also disclosed are methods allowing for the liver-specific delivery of a composition.
    Type: Grant
    Filed: July 17, 1998
    Date of Patent: April 20, 2004
    Assignee: Corgentech, Inc.
    Inventor: Michael J. Mann
  • Hand truck provided with a pusher plate for pushing a load off a platform
    Patent number: 6719521
    Abstract: A hand truck is provided with a pusher plate for pushing a load off its platform. In one embodiment, the hand truck comprises a frame to which the platform for accommodating a load and the wheels are attached and the operating construction is hingeably connected to the frame, wherein the pusher plate on one side is hingeably connected to the first end of the operating construction and on the other side is hingeably connected to the frame via an auxiliary arm. The operating construction extends from a first end close to the platform to handles, for grasping the hand truck with the hands. The pusher plate can be moved across the platform, for pushing a load placed on the platform off the platform.
    Type: Grant
    Filed: March 14, 2002
    Date of Patent: April 13, 2004
    Inventor: Leonardus Johannes Josephus Van Boxtel
  • Derivatives of C2-substituted indan-1-ol compounds, methods for their preparation and use
    Patent number: 6717008
    Abstract: Derivatives of C2-substituted indan-1-ol compounds, processes for their preparation and their use are disclosed. In particular, the invention relates to compounds of the formula I and to their physiologically acceptable salts and physiologically functional derivatives. The compounds are suitable, for example, for use as anorectics.
    Type: Grant
    Filed: August 30, 2002
    Date of Patent: April 6, 2004
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Gerhard Jaehne, Volker Krone, Martin Bickel, Matthias Gossel
  • Insulin-like growth factor agonist molecules
    Patent number: 6716586
    Abstract: Compounds are provided that inhibit the interaction of an IGF with any one of its binding proteins and not to a human IGF receptor. These IGF agonist compounds, which include peptides, are useful to increase serum and tissue levels of active IGFs in a mammal.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: April 6, 2004
    Assignee: Genentech, Inc.
    Inventors: Ross G. Clark, Henry B. Lowman, Iain C. A. F. Robinson
  • Conjugates of soluble peptidic compounds with membrane-binding agents
    Patent number: 6713606
    Abstract: The present invention provides, among other things, soluble derivatives of soluble polypeptides that incorporate membrane binding elements. Methods of making these soluble derivatives, and methods of using these soluble derivatives also are provided.
    Type: Grant
    Filed: July 7, 2000
    Date of Patent: March 30, 2004
    Assignee: Adprotech Limited
    Inventors: Richard Anthony Godwin Smith, Ian Dodd, Danuta Ewa Irena Mossakowska
  • Insulin-like growth factor agonist molecules
    Patent number: 6713451
    Abstract: Compounds are provided that inhibit the interaction of an IGF with any one of its binding proteins and not to a human IGF receptor. These IGF agonist compounds, which include peptides, are useful to increase serum and tissue levels of active IGFs in a mammal.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: March 30, 2004
    Assignee: Genentech, Inc.
    Inventors: Ross G. Clark, Henry B. Lowman, Iain C. A. F. Robinson
  • DNA encoding a growth factor specific for epithelial cells
    Patent number: 6709842
    Abstract: Disccoveries are disclosed that show particular aspects of recombinant DNA technology can be used sucessfully to produce hitherto unknown human keratinocyte growth factor (KGF) protein free of other polypeptides. These proteins can be produced in various functional forms from spontaneously secreting cells or from DNA segments introduced into cells. These forms variously enable biochemical and functional studies of this novel protein as well as production of antibodies. Means are described for determining the level of expression of genes for the KGF protein, for example, by measuring mRNA levels in cells or by measuring antigen secreted in extracellular or body fluids.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: March 23, 2004
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Jeffrey S. Rubin, Paul W. Finch, Stuart A. Aaronson
  • Pigment- containing materials to be added to feeds
    Patent number: 6706278
    Abstract: This invention provides a pigment-containing substance for feed additives consisting of a microorganism culture precipitate which contains a high concentration of carotenoid compounds. This pigment-containing substance for feed additives is resistant to oxygen, light and so on, and can be stably conserved for a long time period.
    Type: Grant
    Filed: May 23, 2001
    Date of Patent: March 16, 2004
    Assignee: Nippon Mitsubishi Oil Corporation
    Inventors: Akira Tsubokura, Hisashi Yoneda, Haruyoshi Mizuta
  • Protein/(poly)peptide libraries
    Patent number: 6706484
    Abstract: The present invention relates to synthetic DNA sequences which encode one or more collections of homologous proteins/(poly)peptides, and methods for generating and applying libraries of these DNA sequences. In particular, the invention relates to the preparation of a library of human-derived antibody genes by the use of synthetic consensus sequences which cover the structural repertoire of antibodies encoded in the human genome. Furthermore, the invention relates to the use of a single consensus antibody gene as a universal framework for highly diverse antibody libraries.
    Type: Grant
    Filed: January 24, 2000
    Date of Patent: March 16, 2004
    Assignee: Morphosys AG
    Inventors: Achim Knappik, Peter Pack, Liming Ge, Simon Moroney, Andreas Plückthun
  • IR-MALDI mass spectrometry of nucleic acids using liquid matrices
    Patent number: 6706530
    Abstract: Mass spectrometry of large nucleic acids by infrared Matrix-Assisted Laser Desorption/Ionization (MALDI) using a liquid matrix is reported.
    Type: Grant
    Filed: May 10, 1999
    Date of Patent: March 16, 2004
    Assignee: Sequenom, Inc.
    Inventor: Franz Hillenkamp
  • System and method for providing composite variance analysis for network operation
    Patent number: 6708137
    Abstract: A system and method collects measurements of network performance metrics and automatically calculates and provides composite variance analysis of such metrics. The system and method may use history of performance data statistics to alert a user about performance of network services that are outside acceptable tolerance or control limits. The technique exposes deviation from accepted measurement tolerances that can, in turn, be categorized in relation to control limits based on defined standard deviation thresholds.
    Type: Grant
    Filed: July 16, 2001
    Date of Patent: March 16, 2004
    Assignee: Cable & Wireless Internet Services, Inc.
    Inventor: Stephen Carley