Abstract: 8-Substituted-2,6-methano-3-benzazocines of general structure I in which A is —CH2—OH, —CH2NH2, —NHSO2CH3, and Y is O, S or NOH are useful as analgesics, anti-diarrheal agents, anticonvulsants, antitussives and anti-addiction medications. 8-Carboxamides, thiocarboxamides, hydroxyamidines and formamides are preferred.

Abstract: Disclosed is an in vitro method for the identification and the concomitant monitoring of the therapy and cure of drug-induced or addictive substance-induced liver damage, in which the occurrence of the human enzyme carbamoyl synthase 1 (CPS 1) or its concentration is determined in serum or plasma samples from patients who are being or have been treated with potentially liver-damaging drugs, or from people who take harmful stimulants and addictive substances or are exposed to hepatotoxic substances.

Abstract: A method for repairing a rotor of a turbine includes providing a rotor having a groove portion defined by a circumferential portion of the rotor. The circumferential portion of the rotor is removed to create an opening to provide access to the groove such that the opening, immediately adjacent the groove, is narrower than the groove. A guide block may be extended into a receiving slot separating a first protruding surface from a second protruding surface of the rotor such that a weld area slot of the guide block extends over at least a portion of the opening. The opening may be welded adjacent the guide block to close at least a portion of the opening.

Abstract: A cold plate apparatus is provided which includes a tube and a casted heat sink member. The tube includes a first metal and first and second ends, with a heat transfer region disposed between the ends. The heat sink includes a second metal that surrounds the heat transfer region of the tube, with the first and second ends of the tube residing outside of the heat sink. The second metal has a lower melting point than the first, and the metals reacted peritectically such that a metallurgical bond exists between the tube and the heat sink. The metallurgical bond includes an alloy layer that was formed during casting of the heat sink member. A thickness of the alloy layer was minimized during casting of the heat sink member to enhance the heat transfer characteristic of the metallurgical bond.

Abstract: The invention provides compounds of the formula: (I) having protein kinase B inhibiting activity: wherein A is a saturated hydrocarbon linker group containing from 1 to 7 carbon atoms, the linker group having a maximum chain length of 5 atoms extending between R1 and NR2R3 and a maximum chain length of 4 atoms extending between E and NR2R3, wherein one of the carbon atoms in the linker group may optionally be replaced by an oxygen or nitrogen atom; and wherein the carbon atoms of the linker group A may optionally bear one or more substituents selected from oxo, fluorine and hydroxy, provided that the hydroxy group when present is not located at a carbon atom a with respect to the NR2R3 group and provided that the oxo group when present is located at a carbon atom a with respect to the NR2R3 group; E is a monocyclic or bicyclic carbocyclic or heterocyclic group; R1 is an aryl or heteroaryl group; and R2, R3, R4 and R5 are as defined in the claims.

Abstract: An electro-thermal actuator device includes a case defining a cavity in which are housed a thermal actuator, an electrical heater and, at least partially, an actuating shaft. The device comprises a multipolar connector for the rapid, secure and reliable coupling to a respective source of electrical power supply for the heater. The connector can be configured as an adapter unit distinct from the case, suitable to transform a traditional electro-thermal actuator device into the actuator device described above.

Abstract: Thermoelectric-enhanced, liquid-cooling apparatus and method are provided for facilitating cooling of one or more components of an electronics rack. The apparatus includes a liquid-cooled structure in thermal communication with the component(s) to be cooled, and a liquid-to-air heat exchanger coupled in fluid communication with the liquid-cooled structure via a coolant loop for receiving coolant from and supply coolant to the liquid-cooled structure. A thermoelectric array is disposed with first and second coolant loop portions in thermal contact with first and second sides of the array. The thermoelectric array operates to transfer heat from coolant passing through the first loop portion to coolant passing through the second loop portion, and cools coolant passing through the first loop portion before the coolant passes through the liquid-cooled structure. Coolant passing through the first and second loop portions passes through the liquid-to-air heat exchanger for cooling thereof.

Abstract: A method for determining current return path integrity in an electric device with a plurality of signal lines and supply lines. A library with at least one reference signal pattern of a near end crosstalk signal on a defined signal line arising from an input signal on another defined signal line is provided, a predetermined signal to a selected signal line of the electric device is applied, the near end crosstalk signal on at least one further signal line of the electric device is detected, said near end crosstalk signal is compared with the corresponding reference signal pattern from the library, and if there is a deviation between the near end crosstalk signal and the corresponding reference signal pattern, an information that there is any defect in the electric device is displayed.

Abstract: The invention relates to the use of eszopiclone for the treatment of low-level, chronic pain and fatigue associated with pain.

Abstract: There are provided eyeglasses in which an elastically deformable locking member comprising a pair of locking claws is projectingly provided in at least one location of an outer peripheral edge of a lens. An angle at which a centerline of one locking claw intersects with a centerline of the other locking claw is 10 to 120 degrees. The locking member is locked to at least either of a lens frame and a nose pad.

Abstract: Generally speaking, systems, methods and media for facilitating user-specified delivery options for e-mail messages are disclosed. Embodiments of the method may include receiving by an e-mail client an indication of contents of an e-mail message and a plurality of intended recipients of the e-mail message and generating the e-mail message based on the received indication. Embodiments may also include receiving an indication of user-specified delivery options for each intended recipient of the message, generating meta-data based on the user-specified delivery options, and adding an indication of the meta-data to the message, such as in the data area of the e-mail message. Embodiments may also include transmitting the e-mail message to a mail server.

Abstract: The simultaneous processing of requests under multiple user identifiers is facilitated. The requests are processed by user servers, in which a user server has an association with a particular user. A user server has a static identity associated therewith and is capable of processing a plurality of requests prior to terminating. The requests are dispatched to the appropriate user servers via a dispatcher server coupled to the user servers.

Abstract: The passage of avatars into and out of regions in a virtual universe is regulated through the use of secure communications between and among the avatar, an authority managing of the region and a trusted third party who maintains a database of avatar characteristics. Permission to move from one virtual region to another is determined based upon the avatar characteristics.

Abstract: There is provided for herein a terminal having a radio transceiver, the radio transceiver having a maximum output power and an operating power. The operating power is limitable to a power limit that less than or equal to the maximum output power and is operator selectable from a set of power limit values so as to reduce interference with other devices operating in the 2.4 GHz spectrum of the ISM band. In one embodiment, the set of power limit values includes the maximum output power and a plurality of additional values. In another embodiment, the set of power limit values includes a plurality of values, the plurality of values including at least first and second values less than 16 dB apart in magnitude.

Abstract: A cationic copolymers of acrylamide obtained by the Hofmann rearrangement, using an alkali and/or alkaline earth hydroxide and an alkali and/or alkaline earth hypohalide, are provided. The copolymers can be used as strengthening agents for paper and/or coagulants. The copolymers have a desalination coefficient (Cd) higher than 0.6, higher than 0.65, or higher than 0.7.

Abstract: An input/output cable port assembly and electromagnetic interference attenuation method are provided. The cable port assembly includes a cable port structure mounted to an electronics rack with an opening for input/output cables to pass therethrough, and multiple bottom ferrite inductor portions and multiple top ferrite inductor portions. The bottom and top ferrite inductor portions include first and second surfaces, respectively. The inductor portions are configured to be stacked within the cable port structure with their first and second surfaces in opposing relation to define at least one ferrite inductor with a central opening defined by the first and second surfaces for input/output cable(s) of the electronics rack to pass. The ferrite inductor attenuates electromagnetic interference resulting from transient or steady state current on the cable(s) passing therethrough.

Abstract: A system and incorporated method is provided for performing high reliability flash updates using firmware residing in a computing environment. The system comprises a nonvolatile memory having a boot sector and an application sector and a volatile memory in processing communication to update the nonvolatile memory. The volatile memory also includes an implemented algorithm that can temporarily store functions necessary to update the nonvolatile memory via a flash update.

Abstract: An input/output cable port assembly and electromagnetic interference (EMI) attenuation method are provided. The port assembly includes a cable port structure for an electronics rack with an opening for input/output cables to pass therethrough, and a first and a second partition. The first and second partitions couple to the cable port structure and reside within the opening. The first partition includes at least one ferrite inductor portion and the second partition includes at least one second ferrite inductor portion. The partitions are configured to be disposed adjacent to each other as adjoining partitions within the cable port structure, and when disposed as adjoining partitions, the first and second ferrite inductor portions mate and define a ferrite inductor with a central opening for input/output cable(s) of the electronics rack to pass. The ferrite inductor attenuates electromagnetic interference resulting from transient or steady state currents on the cable(s) passing therethrough.