Patents Represented by Attorney James A. Nicholson

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  • Method for treatment of gastrointestinal secretory and ulcerogenic disease conditions or symptoms in mammals
    Patent number: 4169155
    Abstract: A new class of chemical compounds and their process of preparation is described. These compounds have valuable properties as anti-secretory, anti-spasmodic, anti-ulcerogenic and anti-diarrheal agents.
    Type: Grant
    Filed: August 18, 1978
    Date of Patent: September 25, 1979
    Assignee: William H. Rorer, Inc.
    Inventors: George H. Douglas, William L. Studt, Stuart A. Dodson
  • Ethynylbenzene compounds and derivatives thereof to treat inflammation, pain or fever
    Patent number: 4168320
    Abstract: Novel ethynylbenzene compounds and derivaties are described. Their use in the treatment of inflammation is also disclosed.
    Type: Grant
    Filed: December 6, 1977
    Date of Patent: September 18, 1979
    Assignee: William H. Rorer, Inc.
    Inventor: Julius Diamond
  • Imidazole amidinoureas for stimulating H.sub.2 -receptors
    Patent number: 4166860
    Abstract: A method of stimulating histamine H.sub.2 -receptors in mammals employing imidazole amidinoureas.
    Type: Grant
    Filed: October 11, 1977
    Date of Patent: September 4, 1979
    Assignee: William H. Rorer, Inc.
    Inventors: George H. Douglas, Bernard J. Burns, Henry F. Campbell
  • Ethynylbenzene compounds and derivatives thereof
    Patent number: 4157449
    Abstract: Hydroxy, alkoxy and acyloxy ethynylbenzene compounds and their derivatives which are useful for the treatment for the relief of inflammation, pain and fever.
    Type: Grant
    Filed: November 23, 1976
    Date of Patent: June 5, 1979
    Assignee: William H. Rorer, Inc.
    Inventor: Julius Diamond
  • Amidinoureas
    Patent number: 4150154
    Abstract: This invention describes novel chemical compounds which are 1-amidino-3-phenylureas. The method of preparing these compounds and their pharmaceutical uses is also disclosed.
    Type: Grant
    Filed: March 3, 1975
    Date of Patent: April 17, 1979
    Assignee: William H. Rorer, Inc.
    Inventors: Julius Diamond, Jerome J. Zalipsky
  • Amidinourea local anesthetics
    Patent number: 4147804
    Abstract: A method for producing local anesthetic action in a patient by administering amidinoureas.
    Type: Grant
    Filed: May 25, 1977
    Date of Patent: April 3, 1979
    Assignee: William H. Rorer, Inc.
    Inventors: Julius Diamond, George H. Douglas
  • Pharmaceutical detergent composition
    Patent number: 4147782
    Abstract: Novel pharmaceutical preparation useful for cleaning the skin of persons affected with acne, chronic oily skin and other skin ailments are disclosed.
    Type: Grant
    Filed: June 24, 1976
    Date of Patent: April 3, 1979
    Assignee: William H. Rorer, Inc.
    Inventors: Robert W. Klein, Mary E. Foxx
  • Medicinal simethicone containing composition and its method of production
    Patent number: 4127650
    Abstract: Simethicone is entrapped in solid, discrete particles of a matrix composition of glycerol and corn syrup solids. A mixture of these particles and a therapeutic antacid overcomes the incompatability of the simethicone and the antacid, due to the shielding action of the matrix composition.
    Type: Grant
    Filed: March 31, 1975
    Date of Patent: November 28, 1978
    Assignee: William H. Rorer, Inc.
    Inventor: John D. Buehler
  • Method for lowering the viscosity of certain agents
    Patent number: 4117116
    Abstract: This invention describes a method of lowering the viscosity of aqueous gels of agents used in pharmaceutical preparations and of aqueous suspensions used as pharmaceutical preparations. Particular gels and suspensions and the viscosity lowering ingredients which are most useful are also described.
    Type: Grant
    Filed: March 31, 1975
    Date of Patent: September 26, 1978
    Assignee: William H. Rorer, Inc.
    Inventors: John D. Buehler, Pravinchandra B. Shah, Robert S. Joslin
  • Amidinoureas
    Patent number: 4117165
    Abstract: This invention describes novel chemical compounds which are 1-amidino-3-phenylureas. The method of preparing these compounds and their pharmaceutical uses is also disclosed.
    Type: Grant
    Filed: November 5, 1975
    Date of Patent: September 26, 1978
    Assignee: William H. Rorer, Inc.
    Inventors: Julius Diamond, Jerome J. Zalipsky
  • Treatment of diarrhea with amidinoureas
    Patent number: 4115564
    Abstract: A new class of chemical compounds and their process of preparation is described. These compounds have valuable properties as anti-diarrheal agents.
    Type: Grant
    Filed: November 3, 1976
    Date of Patent: September 19, 1978
    Assignee: William H. Rorer, Inc.
    Inventors: Julius Diamond, George H. Douglas
  • Amidinoureas
    Patent number: 4115647
    Abstract: A new class of chemical compounds and their process of preparation is described. These compounds have valuable properties as anti-secretory, anti-spasmodic, anti-ulcerogenic and anti-diarrheal agents.
    Type: Grant
    Filed: June 17, 1977
    Date of Patent: September 19, 1978
    Assignee: William H. Rorer, Inc.
    Inventors: George Henry Douglas, William Lyon Studt, Stuart Alan Dodson
  • Process for producing pharmaceutical grade aluminum hydroxide gels
    Patent number: 4105579
    Abstract: A process for producing aluminum hydroxide gels substantially free of sodium ions involves a heterogeneous reaction between an aqueous solution of a water soluble aluminum salt and an aqueous slurry of a water soluble alkaline earth carbonate.
    Type: Grant
    Filed: March 4, 1976
    Date of Patent: August 8, 1978
    Assignee: Barcroft Company
    Inventor: Green B. Glasscock
  • Amidinoureas for the treatment of cardinascular disorders
    Patent number: 4088785
    Abstract: Novel substituted phenylamidinourea compounds and processes for their preparation are disclosed. A method for the treatment of hypertensive disorders is also described.
    Type: Grant
    Filed: February 8, 1977
    Date of Patent: May 9, 1978
    Assignee: William H. Rorer, Inc.
    Inventors: Julius Diamond, George H. Douglas
  • Ethynylbenzene compounds and derivatives thereof for treating pain fever and inflammation
    Patent number: 4075354
    Abstract: Novel ethynylbenzene compounds and derivatives are described. Their use in the treatment of inflammation is also disclosed.
    Type: Grant
    Filed: June 10, 1975
    Date of Patent: February 21, 1978
    Assignee: William H. Rorer, Inc.
    Inventor: Julius Diamond
  • Amidinoureas for treating diarrhea
    Patent number: 4060635
    Abstract: A new class of chemical compounds and their process of preparation is described. These compounds have valuable properties as anti-diarrheal agents.
    Type: Grant
    Filed: March 31, 1975
    Date of Patent: November 29, 1977
    Assignee: William H. Rorer, Inc.
    Inventors: Julius Diamond, George H. Douglas
  • Amidinoureas
    Patent number: 4058557
    Abstract: A new class of chemical compounds and their process of preparation is described. These compounds have valuable properties as anti-secretory, anti-spasmodic, anti-ulcerogenic and anti-diarrheal agents.
    Type: Grant
    Filed: March 30, 1976
    Date of Patent: November 15, 1977
    Assignee: William H. Rorer, Inc.
    Inventors: George Henry Douglas, William Lyon Studt, Stuart Alan Dodson
  • Amidinoureas
    Patent number: 4025652
    Abstract: A new class of chemical compounds and their process of preparation is described. These compounds have valuable properties as anti-diarrheal agents.
    Type: Grant
    Filed: March 31, 1975
    Date of Patent: May 24, 1977
    Assignee: William H. Rorer, Inc.
    Inventors: Julius Diamond, George H. Douglas
  • Preparation of ethynylbenzenes
    Patent number: 4016214
    Abstract: Process for preparing ethynylbenzene compounds by the dehalogenation of .beta.,.beta.,.alpha.-trichlorophenylethane compounds is described.
    Type: Grant
    Filed: September 23, 1975
    Date of Patent: April 5, 1977
    Assignee: William H. Rorer, Inc.
    Inventors: George Henry Douglas, Norman J. Santora
  • Process for making a methenamine salt of an optically active acid
    Patent number: 4001231
    Abstract: Novel salts of hexamethylenetetramine formed from d- or l- enantiamorph of a selected acid are disclosed, and a process for the preparation is described. A new method for the treatment of urinary tract infections is also described.
    Type: Grant
    Filed: March 29, 1973
    Date of Patent: January 4, 1977
    Assignee: William H. Rorer, Inc.
    Inventor: Julius Diamond