Abstract: A multi-step, stereospecific total synthesis of steroids is disclosed. The starting materials for this process are the relatively inexpensive and readily available m-alkoxy acetophenones. The process is suitable for the preparation of racemic or optically active, medicinally valuable steroids, particularly A-ring aromatic steroids. This process features an early optical resolution and a unique asymmetric induction which insures the correct stereochemistry of the final steroidal product.

Abstract: 14.beta.-Hydroxyandrostanes and processes for the preparation thereof in which the 14.beta.-hydroxy group is fabricated internally by means of a novel cyclization of 8,14-seco-4,6,9(11) -androstatrien-3,14,17-triones is disclosed.The 14.beta.-hydroxyandrostanes are useful as precursors for the synthesis of cardenolides and related products.

Abstract: A method and system for a rapid and sensitive method for determining immunologically active materials in a biological fluid by observing an antigen-antibody reaction after application of reactants on the surface of a gel matrix and applying an alternating current thereto.

Abstract: The present disclosure is concerned with 17a-(m-iodobenzoyloxy) substituted D-homosteroids and a process for their manufacture. The compounds are useful as intermediates and also as hormonal agents, particularly progestational agents.

Abstract: The present invention relates to pregnane derivatives of the formula ##STR1## wherein R.sup.1 and R.sup.3 are hydroxyl groups or readily cleavable etherified or esterified hydroxyl groups and R.sup.20 is hydroxymethyl or readily cleavable etherified or esterified hydroxy methyl, formyl, carboxyl or carbalkoxy useful as intermediates for the preparation of 1.alpha.-hydroxycholecalciferols. The present invention also relates to processes for the preparation of the pregnane derivatives and the intermediates thereof.

Abstract: 14.beta.-Hydroxyandrostanes and processes for the preparation thereof in which the 14.beta.-hydroxy group is fabricated internally by means of a novel cyclization of 8,14-seco-4,6,9(11)-androstatrien-3,14,17-triones is disclosed.The 14.beta.-hydroxyandrostanes are useful as precursors for the synthesis of cardenolides and related products.

Abstract: 14 .beta.-Hydroxyandrostanes and processes for the preparation thereof in which the 14.beta.-hydroxy group is fabricated internally by means of a novel cyclization of 8,14-seco-4,6,9(11)-androstatrien-3,14,17-triones is disclosed.The 14.beta.-hydroxyandrostanes are useful as precursors for the synthesis of cardenolides and related products.

Abstract: A bottom vessel head mounted tube within a tube assembly is used to retrieve particulate matter from a fixed bed reactor. Particulate matter enters the device through coinciding inlet ports in the tubes and flows by gravity to the bottom of the inner tube. By shifting the alignment of the inlet ports, flow is stopped and the catalyst sample flows by gravity into a valved receiver which is depressurized before catalyst is recovered. The device samples catalyst at one elevation.

Abstract: Highly specific antibodies to N-desmethyldiazepam are obtained by using as an immunogen 4'-hydrazinocarbonylmethoxy-N-desmethyldiazepam coupled to an immunogenic carrier material such as bovine serum albumin. These antibodies can be employed in immunoassays for N-desmethyldiazepam which is a major metabolite of three important psychoactive drugs diazepam, chlordiazepoxide and clorazepate.

Abstract: Optically active organic compounds are prepared starting from optically inactive reactants by means of an optically active agent which influences the course of the reaction. In particular optically active compounds having a "meso" type carbon atom undergo an intramolecular ring closure in the presence of an optically active agent to yield an optically active product having one additional ring. The present process is particularly useful in the preparation of optically active bicyclic diketones which are important intermediates in the total synthesis of steroids.

Abstract: A medicinal dispensing system comprising a blister package containing up to 1,000 individual doses of a given medication and a sealable envelope, preferably transparent on one side, for the containment of quantities of medication dispensed as per description is disclosed.Attached to one side of the envelope are multiple flaps preprinted with information relating to the chemical composition of the drug, contraindications, potentiating effects when used with other medications, etc. On the other side of the envelope is a space for the encoding of dosage information, frequency of administration and other pertinent information concerning the prescription being filled. The blister sheet contains perforations to allow for the detachment of as many individually-packaged doses of medication as are called for to fill a given prescription.

Abstract: Petroleum fractions may be separated into aromatic rich and paraffinic-rich hydrocarbon streams by the use of methanol/water mixtures having at least 10% water by volume. The paraffinic-rich stream is recovered as raffinate and the aromatic-rich as extract. After the extraction step additional water is added to the extract and raffinate streams where it acts as an anti-solvent to effect separation of the hydrocarbon from the solvent. The water and methanol are then separated for example by flash distillation or by using super critical CO.sub.2 as an extraction solvent.

Abstract: Hydrocarbon conversion catalysts which have become deactivated by the deposition of coke and metal contaminants such as nickel, iron, vanadium, etc., are regenerated under conditions which include temperatures in excess of 1300.degree. F. and the periodic use of an amount of oxygen which is in excess of that required to completely burn the coke to CO.sub.2. In a hydrocarbon conversion process whereby a metal-contaminated heavy feed is contacted at conversion conditions with a cracking catalyst to produce lower boiling hydrocarbon products and a spent catalyst having coke and said metal contaminant deposited thereon and wherein said spent catalyst is reactivated in a regeneration zone at elevated temperatures in the presence of O.sub.2 to produce a regenerated catalyst and a flue gas containing more than 2 vol. % CO, the improvement which comprises periodically increasing the amount of O.sub.2 introduced into said regeneration zone at a temperature in excess of 1300.degree. F. so that the level of O.sub.

Abstract: The present disclosure relates to a compound of the general formula: ##STR1## and the novel antipodes of that compound.

Abstract: A process for the stabilization of a fluidized bed against bubble formation which process comprises a vessel, a plurality of permanently magnetized particles dispersed throughout the bed, and means for fluidizing said particles. The particles are designated as permanently magnetized by virtue of their possessing a coercivity of at least 50 oersteds. The permanently magnetized particles exert magnetic attractive forces upon one another, thereby imparting stability to the fluidized bed. In these beds, fluid throughput rates which are up to 10 or more times the flow rate of said fluid at incipient fluidization of the unmagnetized particles can be achieved with little or no bubbling and at bed pressure drops equal to bed weight.

Abstract: An improvement in a dilution chilling dewaxing process wherein waxy lubricating oil stocks are solvent dewaxed by contacting them with successive increments of cold dewaxing solvent at a plurality of points along the height of a vertical tower divided into a plurality of stages while agitating the oil-solvent mixture in each stage to provide substantially instantaneous mixing of the waxy oil and solvent thereby precipitating wax from the oil while avoiding the well known shock chilling effect. The improvement resides in using as the dewaxing solvent, a mixture selected from the group consisting of (a) methylene chloride and (b) acetone, methylethyl ketone, methanol and mixtures thereof, and wherein the methylene chloride comprises at least about 20 LV% of the dewaxing solvent.

Abstract: A synthetic halloysite which is substantially iron-free is obtained by crystallization from a reaction mixture containing hydrous alumina gel and aqueous silica sol. Metal substituted synthetic halloysites can be prepared by coprecipitation of metal hydroxides with the alumina gel. Hydrocarbons are converted over cracking catalysts derived from these halloysites.

Abstract: A cracking catalyst for promoting the oxidation of carbon monoxide to carbon dioxide during regeneration of the catalyst by the burning of coke therefrom, comprises two distinct crystalline aluminosilicate zeolite particles embedded in an inorganic porous oxide matrix material. The first zeolite is the ultra-stable variety of Y-type zeolite which contains a CO oxidation promoter, such as a Group VIII metal or compound thereof. The second zeolite is a rare earth metal-containing zeolite. A preferred catalyst comprises an ultra-stable Y-type zeolite containing Pt and/or Pd and a rare earth metal exchanged X- or Y-type zeolite, which zeolites are embedded in a silica-alumina or clay matrix.

Abstract: The production of liquid hydrocarbons from coal via liquefaction is enhanced by recovering a bottoms fraction from the coal liquefaction reaction and subjecting the bottoms fraction to alkylation or acylation prior to recycling this bottoms fraction to the liquefaction reaction zone. The introduction of aliphatic hydrocarbon radicals or acyl radicals, including carbon monoxide, into the highly refractory molecules of the bottoms product from coal liquefaction permits additional amounts of the coal to undergo liquefaction at suitable liquefaction conditions.

Abstract: Noxious emissions produced in the process of regenerating catalysts employed in the catalytic cracking of hydrocarbons are reduced by burning the coke on the spent catalyst in a regenerator operated at a temperature greater than 1200.degree. F. to produce flue gas containing less than 2.0 vol.