Patents Represented by Attorney James W. Weinberger
  • Patent number: 5085848
    Abstract: A ferric hydroxide colloid having an alpha-emitting radionuclide essentially on the outer surfaces and a method of forming same. The method includes oxidizing a ferrous hydroxide to ferric hydroxide in the presence of a preselected radionuclide to form a colloid having the radionuclide on the outer surface thereof, and thereafter washing the colloid, and suspending the washed colloid in a suitable solution. The labelled colloid is useful in cancer therapy and for the treatment of inflamed joints.
    Type: Grant
    Filed: April 16, 1991
    Date of Patent: February 4, 1992
    Assignee: The United States of America as Represented by the United States Department of Energy
    Inventors: Robert W. Atcher, John J. Hines
  • Patent number: 5086034
    Abstract: An improved method for the preparation of single phase, fine grained ceramic materials from precursor powder mixtures where at least one of the components of the mixture is an alkali earth carbonate. The process consists of heating the precursor powders in a partial vacuum under flowing oxygen and under conditions where the partial pressure of CO.sub.2 evolved during the calcination is kept to a very low level relative to the oxygen. The process has been found particularly suitable for the preparation of high temperature copper oxide superconducting materials such as YBa.sub.2 Cu.sub.3 O.sub.x "123" and YBa.sub.2 Cu.sub.4 O.sub.8 "124".
    Type: Grant
    Filed: September 28, 1990
    Date of Patent: February 4, 1992
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventors: Uthamalingam Balachandran, Roger B. Poeppel, James E. Emerson, Stanley A. Johnson
  • Patent number: 5082630
    Abstract: A portable fiber optic detector that senses the presence of specific target chemicals in air or a gas by exchanging the target chemical for a fluoroescently-tagged antigen that is bound to an antibody which is in turn attached to an optical fiber. Replacing the fluorescently-tagged antigen reduces the fluorescence so that a photon sensing detector records the reduced light level and activates an appropriate alarm or indicator.
    Type: Grant
    Filed: April 30, 1990
    Date of Patent: January 21, 1992
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventors: Judy K. Partin, Thomas E. Ward, Alan E. Grey
  • Patent number: 5032657
    Abstract: Benzotriazole compounds having the formula: ##STR1## wherein R.sub.1 is H, Cl, or OCH.sub.3 ; R.sub.2 is a hydroxynaphthyl group; and R.sub.3 is a vinyl unsaturated polymerizable group. Homopolymers or copolymers thereof are effective as UV light stabilizers and absorbers.
    Type: Grant
    Filed: May 21, 1990
    Date of Patent: July 16, 1991
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventors: Peter M. Gomez, Hermann H. Neidlinger
  • Patent number: 5032502
    Abstract: A method is disclosed for processing related subject and reference macromolecule populations composed of complementary strands into their respective subject and reference populations of representative fragments and effectuating purification of unique polymorphic subject fragments.
    Type: Grant
    Filed: January 21, 1988
    Date of Patent: July 16, 1991
    Assignee: The United States of America as represented by the United States of Energy
    Inventor: Marvin Stodolsky
  • Patent number: 5030441
    Abstract: A ferric hydroxide colloid having an alpha-emitting radionuclide essentially on the outer surfaces and a method of forming same. The method includes oxidizing a ferrous hydroxide to ferric hydroxide in the presence of a preselected radionuclide to form a colloid having the radionuclide on the outer surface thereof, and thereafter washing the colloid, and suspending the washed colloid in a suitable solution. The labelled colloid is useful in cancer therapy and for the treatment of inflamed joints.
    Type: Grant
    Filed: September 11, 1990
    Date of Patent: July 9, 1991
    Assignee: The United State of America as represented by the United States Department of Energy
    Inventors: Robert W. Atcher, John J. Hines
  • Patent number: 5026927
    Abstract: A homogeneous process for hydrocracking of carbohydrates in the presence of soluble transition metal hydrogenation catalyst with the production of lower polyhydric alcohols. A carbohydrate is contacted with hydrogen in the presence of a soluble transition metal catalyst and a strong base at a temperature of from about 25.degree. C. to about 200.degree. C. and a pressure of from about 15 to about 3000 psi.
    Type: Grant
    Filed: November 16, 1989
    Date of Patent: June 25, 1991
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventors: Mark A. Andrews, Stephen A. Klaeren
  • Patent number: 5022996
    Abstract: A method is provided for separating halogenated hydrocarbons from a fluid feedstream. The fluid feedstream is flowed across a first surface of a polyphosphazene semipermeable membrane. At least one halogenated hydrocarbon from the fluid feedstream permeates through the polyphosphazene semipermeable membrane to a second opposed surface of the semipermeable membrane. Then the permeated polar hydrocarbon is removed from the second opposed surface of the polyphosphazene semipermeable membrane. Outstanding and unexpected separation selectivities on the order of 10,000 were obtained for methylene chloride when a methylene chloride in water feedstream was flowed across the polyphosphazene semipermeable membrane in the invented method.
    Type: Grant
    Filed: April 30, 1990
    Date of Patent: June 11, 1991
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventors: Robert R. McCaffrey, Daniel G. Cummings
  • Patent number: 5021572
    Abstract: The present invention pertains to boron containing thiouracil derivatives, their method of preparations, and their use in the therapy of malignant melanoma using boron neutron capture therapy.
    Type: Grant
    Filed: January 27, 1989
    Date of Patent: June 4, 1991
    Assignee: The United States Department of Energy
    Inventor: Detlef Gabel
  • Patent number: 5019177
    Abstract: A single-crystal, monolithic, tandem, photovoltaic solar cell is described which includes (a) an InP substrate having upper and lower surfaces, (b) a first photoactive subcell on the upper surface of the InP substrate, and (c) a second photoactive subcell on the first subcell. The first photoactive subcell is GaInAsP of defined composition. The second subcell is InP. The two subcells are lattice matched. The solar cell can be provided as a two-terminal device or a three-terminal device.
    Type: Grant
    Filed: November 3, 1989
    Date of Patent: May 28, 1991
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventor: Mark W. Wanlass
  • Patent number: 5006142
    Abstract: The invention is a process for the preparation of high quality oxynitride glasses without resorting to high pressures. Nitrogen-containing compounds such as Si.sub.3 N.sub.4 are first encapsulated in a low melting temperature glass. Particles of the encapsulated nitrogen-containing compound are mixed with other oxide glass-formers and melted in an atmosphere of flowing nitrogen and in the presence of buffering gas to form the oxynitride glass. Glasses containing up to 15 at % nitrogen have been prepared by this method.
    Type: Grant
    Filed: March 28, 1990
    Date of Patent: April 9, 1991
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventors: Jerry R. Weidner, Stanley T. Schuetz, Michael H. O'Brien
  • Patent number: 5002875
    Abstract: A method is disclosed for cloning the gene which encodes a DNA polymerase-exonuclease of Streptococcus pneumoniae. Plasmid pSM22, the vector containing the pneumocccal polA gene, facilitates the expression of 50-fold greater amounts of the PolI enzyme.
    Type: Grant
    Filed: August 28, 1987
    Date of Patent: March 26, 1991
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventors: Sanford A. Lacks, Susana Martinez, Paloma Lopez, Manuel Espinosa
  • Patent number: 4995916
    Abstract: The invention is a process for the recovery of hazardous wastes such as heavy metals and radioactive elements from phenolic resin filter by a circulating a solution of 8 to 16 molar nitric acid at a temperature of 110 to 190 degrees F. through the filter. The hot solution dissolves the filter material and releases the hazardous material so that it can be recovered or treated for long term storage in an environmentally safe manner.
    Type: Grant
    Filed: April 30, 1990
    Date of Patent: February 26, 1991
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventors: David H. Meikrantz, Gary L. Bourne, John N. McFee, Bradley G. Burdge, John W. McConnell, Jr.
  • Patent number: 4995948
    Abstract: An apparatus and process for reducing uranium and/or plutonium oxides to produce a solid, high-purity metal. The apparatus is an electrolyte cell consisting of a first container, and a smaller second container within the first container. An electrolyte fills both containers, the level of the electrolyte in the first container being above the top of the second container so that the electrolyte can be circulated between the containers. The anode is positioned in the first container while the cathode is located in the second container. Means are provided for passing an inert gas into the electrolyte near the lower end of the anode to sparge the electrolyte and to remove gases which form on the anode during the reduction operation. Means are also provided for mixing and stirring the electrolyte in the first container to solubilize the metal oxide in the electrolyte and to transport the electrolyte containing dissolved oxide into contact with the cathode in the second container.
    Type: Grant
    Filed: July 24, 1989
    Date of Patent: February 26, 1991
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventors: David S. Poa, Leslie Burris, Robert K. Steunenberg, Zygmunt Tomczuk
  • Patent number: 4970062
    Abstract: A ferric hydroxide colloid having an alpha-emitting radionuclide essentially on the outer surfaces and a method of forming same. The method includes oxidizing a ferrous hydroxide to ferric hydroxide in the presence of a preselected radionuclide to form a colloid having the radionuclide on the outer surface thereof, and thereafter washing the colloid, and suspending the washed colloid in a suitable solution. The labelled colloid is useful in cancer therapy and for the treatment of inflamed joints.
    Type: Grant
    Filed: May 30, 1989
    Date of Patent: November 13, 1990
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventors: Robert W. Atcher, John J. Hines
  • Patent number: 4967031
    Abstract: A process for the non-catalytic hydrogenation of organic compounds, which contain at least one reducible functional group, which comprises reacting the organic compound, a hydride complex, preferably a transition metal hydride complex or an organosilane, and a strong acid in a liquid phase.
    Type: Grant
    Filed: December 13, 1989
    Date of Patent: October 30, 1990
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventor: R. Morris Bullock
  • Patent number: 4959356
    Abstract: Novel compounds for treatment of brain tumors in Boron Neutron Capture Therapy are disclosed. A method for preparing the compounds as well as pharmaceutical compositions containing said compounds are also disclosed. The compounds are water soluble, non-toxic and non-labile boronated porphyrins which show significant uptake and retention in tumors.
    Type: Grant
    Filed: May 26, 1989
    Date of Patent: September 25, 1990
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventors: Michiko Miura, Detlef Gabel
  • Patent number: 4959158
    Abstract: The invention provides a method of separating a mixed component waste stream in a centrifugal separator. The mixed component waste stream is introduced into the separator and is centrifugally separated within a spinning rotor. A dual vortex separation occurs due to the phase density differences, with the phases exiting the rotor distinct from one another. In a preferred embodiment, aqueous solutions of organics can be separated with up to 100% efficiency. The relatively more dense water phase is centrifugally separated through a radially outer aperture in the separator, while the relatively less dense organic phase is separated through a radially inner aperture.
    Type: Grant
    Filed: March 30, 1989
    Date of Patent: September 25, 1990
    Assignee: The United States of America as represented by the Unitd States Department of Energy
    Inventor: David H. Meikrantz
  • Patent number: 4935943
    Abstract: A corrosion resistant long-term storage container for isolating radioactive waste material in a repository. The container is formed of a plurality of sealed corrosion resistant canisters of different relative sizes, with the smaller canisters housed within the larger canisters, and with spacer means disposed between judxtaposed pairs of canisters to maintain a predetermined spacing between each of the canisters. The combination of the plural surfaces of the canisters and the associated spacer means is effective to make the container capable of resisting corrosion, and thereby of preventing waste material from leaking from the innermost canister into the ambient atmosphere.
    Type: Grant
    Filed: August 30, 1984
    Date of Patent: June 19, 1990
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventors: Donald G. Schweitzer, Mary S. Davis
  • Patent number: H918
    Abstract: Carbohydrates, especially aldose or ketose sugars, including those whose carbonyl group is masked by hemi-acetal or hemi-ketal formation, are decarbonylated by heating the feed carbohydrate together with a transition metal complex in a suitable solvent. Also, primary alcohols, including sugar alditols are simultaneously dehydrogenated and decarbonylated by heating a mixture of rhodium and ruthenium complexes and the alcohol and optionally a hydrogen acceptor in an acceptable solvent. Such defarbonylation and/or dehydrogenation of sugars provides a convenient procedure for the synthesis of certain carbohydrates and may provide a means for the conversion of biomass into useful products.
    Type: Grant
    Filed: October 5, 1988
    Date of Patent: May 7, 1991
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventors: Mark A. Andrews, Stephen A. Klaeren