Patents Represented by Attorney Jones Day

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  • Pharmaceutical compositions of 3-(4-amino-1-oxoisoindolin-2yl)-piperidine-2,6-dione
    Patent number: 8288415
    Abstract: Substituted 2-(2,6-dioxopiperidin-3-yl)phthalimides and 1-oxo-2-(2,6-dioxopiperidin-3-yl)isoindolines are disclosed. The compounds are useful, for example, in reducing the levels of TNF? in a mammal.
    Type: Grant
    Filed: December 10, 2009
    Date of Patent: October 16, 2012
    Assignee: Celgene Corporation
    Inventors: George W. Muller, David I. Stirling, Roger Shen-Chu Chen
  • PD-1 antibodies in combination with a cytokine-secreting cell and methods of use thereof
    Patent number: 8287856
    Abstract: The present invention relates to a method of enhancing the anti-tumor response in a mammal. More particularly, the invention is concerned with combinations comprising a cytokine-secreting cell and an anti-PD-1 antibody, and methods of administering the combination for enhanced immune response to tumor cells in a patient with a cancer.
    Type: Grant
    Filed: July 19, 2010
    Date of Patent: October 16, 2012
    Assignees: BioSante Pharmaceuticals, Inc., Medarex, Inc.
    Inventors: Betty Li, Karin Jooss, Alan J. Korman
  • Ceramic composition for filling bone defects
    Patent number: 8288344
    Abstract: The invention is directed toward a sterile formable implant composition for application to a bone defect site comprising bioactive glass particles in an aqueous carrier solution, the bioactive glass particles being added to a viscous carrier at a concentration ranging from about 68% to about 76% (w/w), the carrier comprising a mixture of glycerol and polyethylene glycol ranging from 24% to 32% (w/w) with the ratio of glycerol to polyethylene glycol ranging from about 45:55 to about 65:35.
    Type: Grant
    Filed: March 15, 2007
    Date of Patent: October 16, 2012
    Assignee: Musculoskeletal Transplant Foundation
    Inventor: Carl Alexander DePaula
  • Methods of screening for compounds for treating spinal muscular atrophy using SMN mRNA translation regulation
    Patent number: 8283116
    Abstract: The present invention provides compounds and assays for the identification and validation of compounds for use in the treatment of spinal muscular atrophy (SMA), in which said compounds up-regulate the post-transcriptional expression of SMN1 or SMN2.
    Type: Grant
    Filed: June 23, 2008
    Date of Patent: October 9, 2012
    Assignee: PTC Therapeutics, Inc.
    Inventors: Anuradha Bhattacharyya, Bansri S. Furia, Meenal Patel, Sergey V. Paushkin, Love Volkova
  • Methods of screening for compounds for treating muscular dystrophy using UTRN mRNA translation regulation
    Patent number: 8283115
    Abstract: The present invention provides compounds and assays for the identification and validation of compounds for use in the treatment of muscular dystrophy (MD), or a form thereof, in which said compounds increase the post-transcriptional expression of a target gene (i.e., mIGF1, ITGA7, or UTRN).
    Type: Grant
    Filed: June 20, 2008
    Date of Patent: October 9, 2012
    Assignee: PTC Therapeutics, Inc.
    Inventors: Westley J Friesen, Nikolai Naryshkin, Meenal Patel, Charles Romfo, Ellen Welch, Yuki Tomizawa, Jin Zhuo
  • Contact query data system and method
    Patent number: 8285712
    Abstract: A processor-implemented method of operating a mobile communication device operable to execute one or more communication applications includes issuing a query for contact data over a communication network, creating a contact resolution object, receiving contact data responsive to the query over the communication network, the contact data comprising communication contact data for the one or more communication applications, associating the contact data received with the contact resolution object, and resolving the contact resolution object to select communication contact data.
    Type: Grant
    Filed: May 22, 2008
    Date of Patent: October 9, 2012
    Assignee: Research In Motion Limited
    Inventors: Anthony F. Scian, Piotr Konrad Tysowski
  • Interleaving multi-energy X-ray energy operation of a standing wave linear accelerator
    Patent number: 8284898
    Abstract: The disclosure relates to systems and methods for interleaving operation of a standing wave linear accelerator (LINAC) for use in providing electrons of at least two different energy ranges, which can be contacted with x-ray targets to generate x-rays of at least two different energy ranges. The LINAC can be operated to output electrons at different energies by varying the power of the electromagnetic wave input to the LINAC, or by using a detunable side cavity which includes an activatable window.
    Type: Grant
    Filed: March 5, 2010
    Date of Patent: October 9, 2012
    Assignee: Accuray, Inc.
    Inventors: Ching-Hung Ho, Stephen Wah-Kwan Cheung, Roger Heering Miller, Juwen Wang
  • Computer-implemented systems and methods for blotter synchronization
    Patent number: 8285630
    Abstract: Computer-implemented systems and methods are disclosed for synchronizing securities order information between an order management system and liquidity source computer systems. An order management system generates a securities order and communicates it to a blotter synchronization module. The blotter synchronization module communicates with liquidity source computer systems to indicate that the securities order is open for execution, and the liquidity source computer systems may respond to request permission to execute the securities order. The blotter synchronization module determines whether to select one of the liquidity source computer systems to execute the securities order.
    Type: Grant
    Filed: November 7, 2008
    Date of Patent: October 9, 2012
    Inventor: Gregg A. Drumma
  • System and method for navigating a mobile device user interface with a directional sensing device
    Patent number: 8285480
    Abstract: An electronic mobile device includes a display for displaying a graphical element. A tilt sensor is configured to sense first and second tilt angles of the mobile device. A processor is coupled to the display and the tilt sensor and configured to move the graphical element relative to the display in a first direction based on the first tilt angle, and to move the graphical element relative to the display in a second direction based on the second tilt angle.
    Type: Grant
    Filed: April 9, 2012
    Date of Patent: October 9, 2012
    Assignee: Research In Motion Limited
    Inventors: Kevin Howard Orr, Alexander Kornilovsky, Alexei Skarine
  • Method and apparatus for deriving presence information using message traffic analysis
    Patent number: 8285312
    Abstract: A method and apparatus for deriving presence information of a mobile device at a presence node in a wireless system, the method having the steps of: analyzing a message received from the mobile device to determine a message type; and allocating a state for the mobile device depending on the message type found in the analyzing step. The apparatus is a presence node for deriving and maintaining presence information of a mobile device in a wireless system, the mobile device communicating with a network node, the presence node having: a communication system for communicating with the network node; a processor; and an application running on the processor, the application having means for analyzing a message received from the mobile device at the network node to determine a message type; and allocating a state for the mobile device depending on the message type found in the analyzing step.
    Type: Grant
    Filed: December 6, 2006
    Date of Patent: October 9, 2012
    Assignee: Research In Motion Limited
    Inventor: Michal Andrzej Rybak
  • Computer-implemented risk evaluation systems and methods
    Patent number: 8280805
    Abstract: Computer-implemented systems and methods are disclosed herein that relate to processes, which construct an empirically derived and statistically based risk evaluation and policy formulation system. For example, a process can be configured so as to accept as input an information base in computer readable form and produce either a single or multistage system composed of alternative decision making strategies.
    Type: Grant
    Filed: December 1, 2008
    Date of Patent: October 2, 2012
    Assignee: SAS Institute Inc.
    Inventors: Clark Richard Abrahams, Mingyuan Zhang
  • Automatic surgical sponge counter and blood loss determination system
    Patent number: 8279068
    Abstract: A surgical sponge detection system includes a device for automatically counting soiled surgical sponges which includes a reader which scans each sponge entered and determines sponge type from a tag affixed to each sponge and a control unit which processes data received from reader contained within sponges entered. The reader includes a non-optical scanner means which can read an indicating means on the sponges even when the indicating means is covered with blood or other body fluids.
    Type: Grant
    Filed: December 13, 2011
    Date of Patent: October 2, 2012
    Assignee: ClearCount Medical Solutions, Inc.
    Inventors: Sharon L. Morris, Dean E. Morris
  • Battery charging assembly
    Patent number: 8280455
    Abstract: A battery charging assembly for charging a battery of a mobile device includes a charging unit, an output assembly and an input assembly. The input assembly is detachably associated with the charging unit and includes an adapter for removable attachment to the charging unit, a power cord, and a plug configured to mate with a style of electrical outlet such that the charging unit is positionable at a remote location from the electrical outlet. The adapter has a latching mechanism for latching the adapter in a receptacle defined in the charging unit.
    Type: Grant
    Filed: July 7, 2010
    Date of Patent: October 2, 2012
    Assignee: Research In Motion Limited
    Inventors: Felipe O. Simoes, Colin N. Todd
  • RNA processing protein complexes and uses thereof
    Patent number: 8278085
    Abstract: The invention provides human protein complexes with endonuclease activity, including tRNA splicing endonuclease activity and 3? end pre-mRNA endonuclease activity, and pre-ribosomal RNA cleavage activity. The invention also provides a splice variant of human Sen2, and human protein complexes comprising the variant. The invention provides human protein complexes with pre-ribosomal RNA cleavage activity. The invention also provides antibodies that immunospecifically bind to a complex described herein or a component thereof, and uses of such antibodies. The present invention also provides methods of preparing and purifying the complexes and uses of the complexes inter alia, in screening, diagnosis, and therapy.
    Type: Grant
    Filed: December 30, 2008
    Date of Patent: October 2, 2012
    Assignee: PTC Therapeutics, Inc.
    Inventors: Christopher R. Trotta, Sergey Paushkin
  • Amine salts of a CRTH2 antagonist
    Patent number: 8278310
    Abstract: Provided are amine salts of {4,6-bis(dimethylamino)-2-(4-(4-(trifluoromethyl)benzamido)benzyl)pyrimidin-5-yl}-acetic acid, processes for their preparation, pharmaceutical compositions containing them, and their use for treating, preventing, or ameliorating one or more symptoms of a CRTH2-mediated disorder or disease.
    Type: Grant
    Filed: June 18, 2008
    Date of Patent: October 2, 2012
    Assignee: Actimis Pharmaceuticals, Inc.
    Inventor: Tai Wei Ly
  • Peer-to-peer and group financial management systems and methods
    Patent number: 8280788
    Abstract: Systems and methods for providing peer-to-peer and group financial management are provided herein. An example system includes a payment processor that executes software instructions for creating and managing electronic payment accounts and an accounts database to store account data from the payment processor. The payment processor may be configured to receive a payment request from a payer, the payment request including information to identify a payee and a payment amount. The payment processor may be further configured to determine if the accounts database includes an account associated with the payee, and based on a determination that the accounts database includes an account associated with the payee, send an electronic message to the payee that notifies the payee of the payment request.
    Type: Grant
    Filed: May 12, 2010
    Date of Patent: October 2, 2012
    Assignee: Visa International Service Association
    Inventor: Jeffrey William Perlman
  • Methods of treating a deficiency of functional tripeptidyl peptidase I (CLN2) protein
    Patent number: 8277800
    Abstract: The present invention relates to a method for treating a patient having disorder characterized by a deficient amount of functional CLN2 protein in the affected cells, which comprises administering to the patient an amount of CLN2 protein effective to reduce or eliminate the symptoms caused by the deficiency in CLN2 protein.
    Type: Grant
    Filed: August 29, 2011
    Date of Patent: October 2, 2012
    Assignee: University of Medicine and Dentistry of New Jersey
    Inventors: Peter Lobel, David Sleat
  • System, method, and computer-readable medium for selecting a network for connectivity and handover based on application requirements
    Patent number: 8279831
    Abstract: A system, method, and computer-readable medium are provided for choosing a network for connection and handover based on the application requirements of a multi-mode, multi-radio user equipment. The selection of the network for connectivity and handover is based on one or more of the invoking of an application, the invoking of a second application, and the closing of an application.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: October 2, 2012
    Assignee: SNRLabs Corporation
    Inventors: Chaitali Sengupta, Yuan Kang Lee
  • Humanized anti-factor D antibodies and uses thereof
    Patent number: 8273352
    Abstract: The invention relates to anti-Factor D antibodies, their nucleic acid and amino acid sequences, the cells and vectors that harbor these antibodies and their production and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation. These antibodies are useful for diagnostics, prophylaxis and treatment of disease.
    Type: Grant
    Filed: April 27, 2009
    Date of Patent: September 25, 2012
    Assignee: Genentech, Inc.
    Inventors: Arthur Huang, Robert Kelley, Henry Lowman, Menno Van Lookeren Campagne, Charles Winter
  • Method and system for evaluating vocabulary similarity
    Patent number: 8275306
    Abstract: A method, system and processor-readable storage medium for evaluating vocabulary similarity are disclosed. A generic rate may be determined for each word in a plurality of first responses. Each first response may respond to one of a plurality of first prompts. At least one first response may respond to each of the first prompts. A specific rate may be determined for each word in a plurality of second responses, which each respond to a second prompt. A target response may be received that is associated with the second prompt and has a plurality of words. A vocabulary similarity index may be computed for the target response based on one or more generic rates and on or more specific rates. A determination of whether the target response is off-topic may be made based on the vocabulary similarity index for the target response.
    Type: Grant
    Filed: April 20, 2006
    Date of Patent: September 25, 2012
    Assignee: Educational Testing Service
    Inventor: Yigal Attali