Abstract: Biomedical devices with antimicrobial coatings are provided. One or more surfaces of the device are coated with a cationic peptide, cationic proteins, or mixtures thereof to impart antimicrobial properties to the surface.
Type:
Grant
Filed:
December 19, 2002
Date of Patent:
October 16, 2007
Assignee:
Johnson & Johnson Vision Care, Inc.
Inventors:
Mark Willcox, Emma Hume, Nerida Cole, Yulina Aliwarga, Zanini Diana
Abstract: The present invention relates to compositions comprising poly-HEMA having a peak molecular weight between about 25,000 and about 100,000 , preferably between 25,000 and 80,000 and a polydispersity of less than about 2 to less than about 3.8 respectively and covalently bonded thereon, at least one cross-linkable functional group. The present invention further relates to low polydispersity poly-HEMA suitable for making the crosslinkable prepolymers, processes for functionalizing and purifying said poly-HEMA to form said crosslinkable prepolymers, viscous solutions made from said crosslinkable prepolymers, hydrogels made from said viscous solutions and articles made from said crosslinkable polymers, hydrogels and viscous solutions.
Type:
Grant
Filed:
November 8, 2004
Date of Patent:
August 14, 2007
Assignee:
Johnson & Johnson Vision Care, Inc
Inventors:
Ture Kindt-Larsen, Per Wolff, Jens-Erik Sørensen, Frederik Resen Steenstrup, Hèlène Rossignol, Frank F. Molock
Abstract: The present invention relates to wettable silicone hydrogels comprising the reaction product of at least one siloxane containing component and at least one reactive, hydrophilic polymeric internal wetting agent. The present invention further relates to silicone hydrogel contact lenses comprising at least one oxygen permeable component, and an amount of reactive, hydrophilic polymeric internal wetting agent sufficient to impart wettability to said device.
Type:
Grant
Filed:
September 30, 2004
Date of Patent:
July 31, 2007
Assignee:
Johnson & Johnson Vision Care, Inc.
Inventors:
Walter R. Laredo, Stephen C. Arnold, Kevin McCabe, Susan Orr, Azaam Alli
Abstract: This invention relates to wettable biomedical devices comprising amphiphilic block copolymers. The amphiphilic block copolymers are useful as internal wetting agents for biomedical applications, such as implantable devices, ophthalmic devices and in one embodiment, contact lenses.
Abstract: The present invention relates to (meth)acrylamide monomers of the formula: wherein R is H or CH3, R1 is selected from H, substituted and unsubstituted alkyl groups having 1 to 8 carbon atoms, substituted and unsubstituted benzene and toluene groups and and R2, R3 and R4 are independently selected from alkyl groups having 1 to 8 carbon atoms, substituted and unsubstituted benzene and toluene groups, and —OSiR5R6R7 wherein R5, R6 and R7 are independently selected from the group consisting of straight or branched alkyl groups having 1 to 4 carbon atoms. Polymers made therefrom are also disclosed.
Abstract: This invention includes a wettable biomedical device containing a high molecular weight hydrophilic polymer and a hydroxyl-functionalized silicone-containing monomer.
Type:
Grant
Filed:
September 6, 2002
Date of Patent:
May 30, 2006
Inventors:
Kevin P. McCabe, Frank F. Molock, Gregory A. Hill, Azaam Alli, Robert B. Steffen, Douglas G. Vanderlaan, Kent A Young, James D. Ford
Abstract: The present invention relates to compositions comprising poly-HEMA having a peak molecular weight between about 25,000 and about 100,000, preferably between 25,000 and 80,000 and a polydispersity of less than about 2 to less than about 3.8 respectively and covalently bonded thereon, at least one cross-linkable functional group. The present invention further relates to low polydispersity poly-HEMA suitable for making the crosslinkable prepolymers, processes for functionalizing and purifying said poly-HEMA to form said crosslinkable prepolymers, viscous solutions made from said crosslinkable prepolymers, hydrogels made from said viscous solutions and articles made from said crosslinkable polymers, hydrogels and viscous solutions.
Type:
Grant
Filed:
February 14, 2003
Date of Patent:
January 25, 2005
Assignee:
Johnson & Johnson Vision Care, Inc.
Inventors:
Ture Kindt-Larsen, Per Wolff, Jens-Erik Sørensen, Frederik Resen Steenstrup, Hélène Rossignol, Frank F. Molock
Abstract: Biomedical devices with stable, hydrophilic and antimicrobial coatings are provided. The coatings are formed using a coupling agent to bond a carboxyl containing hydrophilic coating to the surface by ester or amide linkages.
Type:
Grant
Filed:
February 7, 2000
Date of Patent:
March 18, 2003
Assignee:
Johnson & Johnson Vision Care, Inc.
Inventors:
Douglas G. Vanderlaan, David C. Turner, Joe M. Wood
Abstract: Disclosed is an improved process for the continuous production of aromatic carboxylic acids by the liquid-phase oxidation of an alkyl aromatic compound with an oxygen-containing gas in the presence of oxidation catalyst which results in reduced wastewater generation, reduced condensing capacity requirements, and, optionally, increased power recovery, and. The process effectively utilizes the heat of reaction in the process of removing excess water generated from the reaction and minimizes the loss of solvent used as the carrier for the reaction catalyst by removing reactor off-gas directly into a water removal column for distillation. A portion of the overhead aqueous vapors are removed from the top of the water removal column as a vapor distillate, with the remaining overhead aqueous vapors being condensed then subsequently refluxed to the fractionating zone of the water removal column.
Type:
Grant
Filed:
June 4, 2001
Date of Patent:
January 7, 2003
Assignee:
Eastman Chemical Company
Inventors:
Harold David Miller, Jr., Robert Lin, Marcel de Vreede
Abstract: Coated articles having improved chemical resistance comprising an article formed from a moldable polymer coated on at least one surface with a coating composition comprising at least one vinyl ether oligomer compound, and at least one photoinitiator are disclosed. Coatings which also contain at least one acrylate compound and/or at least one epoxy compound are also disclosed. The articles are preferably made from polyesters. Methods for coating such articles are also disclosed.
Type:
Grant
Filed:
January 21, 2000
Date of Patent:
October 1, 2002
Assignee:
Eastman Chemical Company
Inventors:
Eric Jon Moskala, Louis Thomas Germinario, David Gayle Salyer
Abstract: Disclosed is a process for the purification of a polyester precursor wherein a polyester oligomer derived from terephthalic acid and one or more glycols or diols is purified or decolorized by hydrogenating the oligomer to convert colored impurities to colorless compounds and thereby improve the color of the oligomer. The colored impurities are present in the terephthalic acid used to prepare the oligomers and are formed during the manufacture of terephthalic acid. The purified/decolorized oligomer obtained from the disclosed process may be used to prepare high molecular weight polyesters.
Type:
Grant
Filed:
March 20, 2001
Date of Patent:
April 30, 2002
Assignee:
Eastman Chemical Company
Inventors:
Charles Edwan Sumner, Jr., Ronald Buford Sheppard
Abstract: The present invention relates to a polyester-platelet particle composite comprising at least one polyester having dispersed therein a platelet particle dispersion comprising chalcogen or platelet particles and at least one water dissipatible polymer.
Type:
Grant
Filed:
August 1, 2000
Date of Patent:
March 19, 2002
Inventors:
Jack Wesley Trexler, Jr., Rodney Layne Piner, Sam Richard Turner, Robert Boyd Barbee
Abstract: The present invention relates to new polyester compositions, novel processes to prepare molded articles from these new polyester compositions, and novel containers fabricated from polyester/clay composites for food and beverages. The processing methods employed in this invention enable containers to be formed which exhibit excellent clarity. Specifically, the present invention relates to a process comprising forming a parison from a composite composition comprising about 0.01 to about 25 weight % platelet particles dispersed in at least one polyester at a processing temperature which is at least 50° above the Tg of said polyester; and molding said parison into a clear, thin walled article.
Type:
Grant
Filed:
December 22, 1997
Date of Patent:
January 8, 2002
Assignee:
Eastman Chemical Company
Inventors:
Shriram Bagrodia, John Walker Gilmer, Kab Sik Seo, Sam Richard Turner
Abstract: The present invention relates to a large molded polyester container weighing greater than about 200, and preferably between about 200 and about 800 grams. Specifically, the present invention relates to polyester containers having a volume of several gallons. In one embodiment the container is a bottle formed from a diacid component comprising up to about 96.5 mol % terephthalic acid or naphthalene dicarboxylic acid and a glycol component, wherein said polyester possesses an IV of about 0.75 to about 0.85.
Abstract: This invention relates to polyester compositions that possess improved gas barrier properties. The novel copolyester blends comprise repeat units of phenylenedi(oxyacetic acid). Such copolyesters with improved gas barrier properties are useful in packaging applications where low gas permeability are required for protection or preservation of the contents.
Type:
Grant
Filed:
June 14, 1999
Date of Patent:
July 3, 2001
Assignee:
Eastman Chemical Company
Inventors:
Martin E. Rogers, Robert B. Barbee, David R. Fagerburg, Timothy E. Long
Abstract: This invention relates to a visually clear blend of thermoplastic polymers comprising a polyetherimide and a polyester of (a) an acid component comprising 2,6-naphthalene dicarboxylic acid and (b) a glycol component comprising at least one glycol selected from the group consisting of ethylene glycol, 1,3-trimethylene glycol, 1,4-butanediol, 1,5-pentanediol, 1,6-hexanediol, 1,7-heptanediol, neopentyl glycol, 1,4-cyclohexanedimethanol and diethylene glycol.
Abstract: The present invention involves the preparation and use of polyester blend containing at least one acid terminated polyamide which give the improved color as compared to the prior art. The present invention comprises polyester blend composition having improved color comprising:
(A) about 99.98 to about 95 weight percent of a polyester which comprises
(1) a dicarboxylic acid component comprising repeat units from at least 85 mole percent terephthalic acid, and
(2) a diol component repeat units from at least 85 mole percent ethylene glycol, based on 100 mole percent dicarboxlic acid and 100 mole percent diol; and
(B) acid terminated polyamide.
Type:
Grant
Filed:
October 9, 1998
Date of Patent:
May 29, 2001
Assignee:
Eastman Chemical Company
Inventors:
Emily Tedrow Bell, James Rodney Bradley, Timothy Edward Long, Steven Lee Stafford
Abstract: A method and apparatus for determining the stretching characteristics of a polymer composition suitable for use in manufacturing a thermoplastic article, such as a bottle and preferably a bottle having PET, PEN and mixtures thereof, are provided. The method includes the steps of heating a bottle preform of the polymer composition to at least its glass transition temperature then free-blowing the preform in a manner so that the inflation pressure is varied inversely relative to the expansion of the article during at least a portion of the inflation step. An apparatus for free-blowing the thermoplastic articles in accordance with the method is also disclosed.
Abstract: The present invention recites a method comprising reacting in a solvent in the presence of a base
a) at least one diacidic monomer comprising about 1 to 100 mole % of at least one light-absorbing monomer having a light absorption maximum between about 300 nm and about 1200 nm and 99-0 mole % of a non-light absorbing monomer which does not absorb significant light at wavelengths above 300 nm or has a light absorption maximum below 300 nm, with
b) an organic compound of Formula II
X—B—X1
wherein B is a divalent organic radical to form a light absorbing composition comprising a mixture of a polymer having the formula
and a cyclic compound having the general formula
wherein B is as defined above; n is at least 2, m is 1, 2, 3 or 4 and A comprises the residue of a diacidic monomer comprising about 1 to 100 mole % of at least one light-absorbing monomer having a light absorption maximum between about 300 nm and about 1000 nm and wherein the remaining portion of A
Type:
Grant
Filed:
May 26, 1999
Date of Patent:
March 6, 2001
Assignee:
Eastman Chemical Company
Inventors:
Max Allen Weaver, James John Krutak, Sr., Brian Edison Maxwell, Gerry Foust Rhodes, Samuel David Hilbert, Jean Carroll Fleischer, William Whitfield Parham