Abstract: A keyless frictional shaft locking device with integrated frictional drum conveyor pulley end disc is disclosed. The end disc is concentrically centered around a keyless frictional locking device, and the locking device is configured so as to lock around a shaft while, at the same time, effectuating a radially outward expansion of the end disc so that the end disc may securely fit within the ends of a drum of a drum conveyor pulley without the need for welding of either the end disc to the drum, or the locking device to the end disc.

Abstract: The invention relates to an aldehyde conversion method comprising putting an aldehyde into contact with oxygenated water and with a catalyst, under oxidation conditions, wherein the catalyst is a molecular sieve with pores of a diameter of at least 0.52 nm and has an empirical formula in a calcined and dehydrated form of (SnxTiySi1-x-y-zGez)O2 wherein x is a molar fraction of the tin and has a value between 0.001 and 0.1; y is a molar fraction of titanium and has a value from zero to 0.1; and z is the molar fraction molar of the germanium and has a value from zero to 0.08.

Abstract: An apparatus and method is provided which allows transfer of DC electrical power across a transparent or semitransparent medium such as glass. Electrical power transfer is achieved using a suitable optical source (matched visible light or infrared LED or LD arrays are best suited) that illuminates a matched solar cell array on the other side of the medium.

Abstract: The present invention relates to identification of a receptor for a satiety factor, which is involved in body weight homeostasis. Mutations in this receptor are associated with obese phenotypes. In particular, the present invention relates to identification and characterization of the receptor for leptin, including a naturally occurring soluble form of the receptor that is expected to modulate leptin activity, in particular to agonize leptin activity. The invention further relates to the nucleic acids encoding the receptor, and to methods for using the receptor, e.g., to identify leptin analogs, therapeutically, such as in gene therapy or in soluble form as an agonist or antagonist of leptin activity, or diagnostically.

Abstract: Receptor recognition factors exist that recognizes the specific cell receptor to which a specific ligand has been bound, and that may thereby signal and/or initiate the binding of the transcription factor to the DNA site. The receptor recognition factor is in one instance, a part of a transcription factor, and also may interact with other transcription factors to cause them to activate and travel to the nucleus for DNA binding. The receptor recognition factor appears to be second-messenger-independent in its activity, as overt perturbations in second messenger concentrations are of no effect. The concept of the invention is illustrated by the results of studies conducted with interferon (IFN)-stimulated gene transcription, and particularly, the activation caused by both IFN? and IFN?. Specific DNA and amino acid sequences for various human and murine receptor recognition factors are provided, as are polypeptide fragments of two of the ISGF-3 genes, and antibodies have also been prepared and tested.

Abstract: Nucleosides and nucleotides are disclosed that are linked to detectable labels via a cleavable linker group.

Abstract: Tomographic methods and device for obtaining images of microscopic specimens such as Pap smears.

Abstract: A system for dispensing pill- or capsule-form medications (61) in desired doses (60). The system comprises a dispensing device (35), which includes a cartridge (20, 40) rotatable relative to a housing or frame (10) and provided with discrete dosage compartments (27, 47) for desired doses of medication. The cartridge (20, 40) is manipulated by elements (18, 18a, 18b; 14a, 14b, 15, 18, 19), whereby each separate dosage compartment (27, 47) is rotatable relative to the housing or frame (10) to a dispensing point (4, 12) for the dose of medication (60). A signalling device (75, 76) producing a sound and/or light signal activates at pre-programmed limes. An electronics unit (19, 55) containing a dispensing program is reprogrammable by means of an external programming device (36, 66, 101, 102).

Abstract: An apparatus and method for recovering bioproducts from a feed solution. In one embodiment, the apparatus includes a module housing, a membrane means disposed in the housing for filtering the bioproducts from the feed solution wherein a portion of the membrane means is coated with a polymeric coating, and an adsorbent bed disposed in the housing for retaining the bioproducts which permeate through the membrane, wherein the apparatus is adapted to allow fractionation and purification of the retained bioproducts from the bed by elution.