Patents Represented by Attorney Lahive & Cockfield, LLP
  • Patent number: 7925079
    Abstract: The present invention provides a method and system for pattern recognition and processing. Information representative of physical characteristics or representations of physical characteristics is transformed into a Fourier series in Fourier space within an input context of the physical characteristics that is encoded in time as delays corresponding to modulation of the Fourier series at corresponding frequencies. Associations are formed between Fourier series by filtering the Fourier series and by using a spectral similarity between the filtered Fourier series to determine the association based on Poissonian probability. The associated Fourier series are added to form strings of Fourier series. Each string is ordered by filtering it with multiple selected filters to form multiple time order formatted subset Fourier series, and by establishing the order through associations with one or more initially ordered strings to form an ordered string.
    Type: Grant
    Filed: December 23, 1998
    Date of Patent: April 12, 2011
    Inventor: Randell L. Mills
  • Patent number: 7902339
    Abstract: Antibodies that bind to a 40 kDa protein which is expressed on tumors, but is not expressed on normal adult hemopoietic cells are disclosed. Also disclosed are methods for production and the use of such antibodies.
    Type: Grant
    Filed: July 21, 2006
    Date of Patent: March 8, 2011
    Assignee: University of Massachusetts
    Inventors: Kenneth L. Rock, Dancella Fernandes
  • Patent number: 7875277
    Abstract: The present invention relates to compositions and methods for detecting and inhibiting squamous cell carcinoma using agents that target the laminin 5 alpha 3 G4-G5 domain.
    Type: Grant
    Filed: April 14, 2008
    Date of Patent: January 25, 2011
    Assignees: The Dept. of Veterans Affairs Office of The General Counsel, The Board of Trustees of the Leland Stanford Junior University
    Inventor: M. Peter Marinkovich
  • Patent number: 7874982
    Abstract: A surgical access system for providing access to a surgical site in a patient includes a surgical access device defining a port and a light emitter coupled to the surgical access device for illuminating the port. The light emitter preferably comprises an elongated shaft having a light transmitting element housed therein, which emits light transmitted to the elongated shaft from a light source. The elongated shaft is configured to be inserted in an elongated channel in the access device. The elongated channel has or forms a window for transmitting light emitted by the light emitter into the interior of the access device.
    Type: Grant
    Filed: November 2, 2005
    Date of Patent: January 25, 2011
    Assignee: DePuy Spine, Inc.
    Inventors: Sean Selover, Sara Dziedzic, Steve Connolly, Sheryl Frank, Lorenzo Vaccarella
  • Patent number: 7875278
    Abstract: The invention pertains to anti-PSMA antibodies that lack fucosyl residues. The antibodies of the invention exhibit increased antibody-dependent cellular cytotoxicity (ADCC) activity as compared to the fucosylated form of the antibodies. The invention also provides host cells that express the anti-PSMA antibodies that lack fucosyl residues, wherein the host cells are deficient for a fucosyl transferase. Methods of using the antibodies to inhibit the growth of PSMA+ cells, such as tumor cells, are also provided.
    Type: Grant
    Filed: February 17, 2006
    Date of Patent: January 25, 2011
    Assignee: Medarex, Inc.
    Inventors: Josephine M. Cardarelli, David B. Passmore, Jenny Albanese, Lei Zhu
  • Patent number: 7865350
    Abstract: Methods and systems for partitioning objects in modeling environments are disclosed. The modeling environments enable users to partition an object (parent object) to include other objects (child objects). The parent object may reference the child objects (referenced objects). The child objects may be subsystems in the hierarchy of the parent object or modules (or units) in the partitioning of the parent object. The child objects may be encapsulated so that changes in the parent object do not affect the child objects. The partition of the parent object may allow users to load and compile the parent object incrementally. The partition of the parent object may also allow users to generate code for the parent object incrementally.
    Type: Grant
    Filed: June 23, 2008
    Date of Patent: January 4, 2011
    Assignee: The MathWorks, Inc.
    Inventors: Michael David Tocci, Ricardo Monteiro, Mojdeh Shakeri, Pieter J. Mosterman
  • Patent number: 7863419
    Abstract: The invention provides a method of producing aglycosylated Fc-containing polypeptides, such as antibodies, having desired effector function. The invention also provides aglycosylated antibodies produced according to the method as well as methods of using such antibodies as therapeutics.
    Type: Grant
    Filed: February 22, 2006
    Date of Patent: January 4, 2011
    Assignee: Biogen Idec MA Inc.
    Inventors: Frederick R. Taylor, Ellen Garber
  • Patent number: 7865305
    Abstract: A navigation server and the like capable of making a navigation device 200 output a route having adequacy in view of various circumstances is provided. A navigation server 100 recognizes a navigation route r(k) for guiding the automobile 2 to the destination position p2 which is set according to the first algorithm by the navigation device 200. Further, a support route R(k) for guiding the automobile 2 from a current position (or a departure position) p1 to the destination position p2 which is set according to the first algorithm is recognized. Still further, a first index c1(k) representing an adequacy of the navigation route r(k) in view of the second algorithm is evaluated. On condition that the first index c1(k) satisfies a predetermined condition, the support route R(k) is output in place of the navigation route r(k) by the navigation device 200.
    Type: Grant
    Filed: July 3, 2008
    Date of Patent: January 4, 2011
    Assignee: Honda Motor Co., Ltd.
    Inventors: Koji Sengoku, Aiko Sugawara, Masakuni Tsuge, Masayuki Arai, Yoshitaka Kinoshita
  • Patent number: 7865254
    Abstract: A method of manipulating a block diagram model with a plurality of graphical modeling components by defining an open loop anywhere on the block diagram model is provided. Graphical modeling components in series with the open loop may be automatically recognized and a plurality of parameters of the graphical modeling components in series with the open loop may be displayed on a display device. A user may simultaneously tune the parameters of the graphical modeling components in series with the open loop. Factorization points breaking the block diagram model in two disconnected parts may be identified in the block diagram model. A virtual graphical model may be generated by replacing a pattern of the graphical modeling components between two factorization points with a single graphical modeling component representing the pattern.
    Type: Grant
    Filed: October 24, 2007
    Date of Patent: January 4, 2011
    Assignee: The MathWorks, Inc.
    Inventors: Pascal Gahinet, John Glass, Alec Stothert, Craig Buhr
  • Patent number: 7851791
    Abstract: Provided is a thin film transistor (TFT) which uses CIS (CuInSe2), including Se, which is a chalcogen-based material, and can provide a rectifying function, and electric and optical switching functions of a diode. The TFT according to the present invention includes, a substrate, a gate electrode formed on a portion of the substrate, an insulating layer covering the substrate and a gate electrode, a plurality of CIS (CuInSe2) films formed on the insulating layer so as to cover the region where the gate electrode is formed; and source/drain regions separated from each other so as to comprise a trench exposing a portion of a surface of the CIS films.
    Type: Grant
    Filed: February 7, 2008
    Date of Patent: December 14, 2010
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Sang Su Lee, Kibong Song, Jeong Dae Suh, Keongam Kim, Doo-Hee Cho
  • Patent number: 7851163
    Abstract: Immunoassay for the determination of parathyroid hormone activity in a sample, and for the diagnosis, etiology and treatment of calcium metabolism disturbances, osteopathies and hyper- or hypoparathyroidisms. The parathyroid hormone activity is measured with the aid of an antibody which binds to an epitope in the region of the receptor binding structure 15 to 22 of the parathyroid hormone, and an antibody which recognizes whether the amino-terminal end 1 to 3 of the parathyroid hormone is intact. The assay permits the antagonistic characteristics of some parathyroid hormone fragments to be taken into account.
    Type: Grant
    Filed: December 18, 2000
    Date of Patent: December 14, 2010
    Assignee: Immundiagnostik, AG
    Inventors: Franz Paul Armbruster, Albert Missbichler, Heinrich Schmidt-Gayk, Heinz-J├╝rgen Roth
  • Patent number: 7846602
    Abstract: A thermoelectric conversion apparatus has an evaporator for heating a working medium in liquid-phase to evaporate the working medium, an electric generator for forming a concentration cell for electric power generation when it is supplied with a reactive gas and the working medium evaporated by the evaporator, and a gas-liquid separator for being supplied with a mixed gas of the working medium and a cathode off-gas discharged from the electric generator and separating the mixed gas into the working medium and the reactive gas. The thermoelectric conversion apparatus also has an anode supply passage for supplying the reactive gas separated by the gas-liquid separator to the electric generator, and a cathode supply passage for supplying the working medium separated by the gas-liquid separator through the evaporator to the electric generator.
    Type: Grant
    Filed: April 11, 2007
    Date of Patent: December 7, 2010
    Assignee: Honda Motor Co., Ltd.
    Inventors: Atsushi Kamachi, Shunsuke Itami
  • Patent number: 7846440
    Abstract: The present invention provides a novel class of monoclonal antibodies which bind ErbB3 receptor and inhibits various ErbB3 functions. In a particular embodiment, the antibodies are capable of binding to ErbB3 and inhibiting ligand mediated phosphorylation of the receptor.
    Type: Grant
    Filed: February 15, 2008
    Date of Patent: December 7, 2010
    Assignee: Merrimack Pharmaceuticals, Inc.
    Inventors: Birgit Schoeberl, Ulrik Nielsen, Michael Feldhaus, Arumugam Muruganandam, David Buckler
  • Patent number: 7846307
    Abstract: The invention provides a high-pressure hydrogen production apparatus for preventing hydrogen gas from leaking toward an anode side and for obtaining excellent electrolytic efficiency. The apparatus includes a single cell having a solid polymer electrolyte membrane, power feeders, separators, and fluid channels provided in respective separators. High-pressure hydrogen gas accompanied by water is obtained in the fluid channel by supplying water to the fluid channel and applying current to each power feeder to electrolyze water. The obtained hydrogen gas and water are subjected to gas-liquid separation in a second compartment of a high-pressure vessel, and hydrogen gas thus separated is used to press a barrier member towards the single cell. The separated water is supplied to the fluid channel through the hydrogen gas guide channel.
    Type: Grant
    Filed: May 10, 2006
    Date of Patent: December 7, 2010
    Assignee: Honda Motor Co., Ltd.
    Inventors: Kenji Taruya, Masanori Okabe, Koji Nakazawa
  • Patent number: 7847105
    Abstract: A method of forming a CBI CC-1065 analog utilizes NH2 as a starting material, where R3 is H or alkyl and R6 is H, substituted or unsubstituted lower alkyl, cyano, or alkoxy. Intermediates (I) are used and are claimed.
    Type: Grant
    Filed: October 18, 2006
    Date of Patent: December 7, 2010
    Assignee: Medarex, Inc.
    Inventors: Sanjeev Gangwar, Qian Zhang
  • Patent number: 7845135
    Abstract: The present invention relates to a window frame. According to the present invention, there is provided a window frame, which comprises: a frame unit having a pair of side jamb frames for defining both side ends of the frame unit, an upper jamb frame for defining an upper end thereof, and a sill frame for defining a lower end thereof coupled to each other to have a rectangular frame shape, the frame unit having at least one receiving groove formed in an outer wall surface thereof along a length direction thereof; and corner angles coupled to the frame unit to surround the outer wall surface of the frame unit at corners thereof, each of the corner angles having a concavo-convex portion to be received in the receiving groove, the corner angle having at least one rib protruding from an outer wall surface thereof along a length direction thereof.
    Type: Grant
    Filed: February 5, 2008
    Date of Patent: December 7, 2010
    Inventor: Peter Sibbett
  • Patent number: 7846589
    Abstract: A fuel cell stack includes unit cells. At one side of the unit cells, an oxygen-containing gas supply passage and a fuel gas discharge passage having different opening areas are provided. At the one side of the unit cells, a recess is provided near the fuel gas discharge passage having a relatively small opening area. A cell voltage terminal is provided in the recess such that the cell voltage terminal does not protrude outwardly from the side of the unit cells.
    Type: Grant
    Filed: October 25, 2005
    Date of Patent: December 7, 2010
    Assignee: Honda Motor Co., Ltd.
    Inventors: Masaaki Sakano, Masaru Oda, Kentaro Nagoshi
  • Patent number: 7846613
    Abstract: A power generation cell includes a membrane electrode assembly and first and second metal separators sandwiching the membrane electrode assembly. Ridge members are formed integrally on the second metal separator, and these ridge members contact a first seal member of the first metal separator under pressure to form an inlet connection channel and an outlet connection channel. The coolant supply passage and the coolant flow field are connected through the inlet connection channel and the coolant discharge passage and the coolant flow field are connected through the outlet connection channel.
    Type: Grant
    Filed: December 15, 2004
    Date of Patent: December 7, 2010
    Assignee: Honda Motor Co., Ltd.
    Inventors: Seiji Sugiura, Shuhei Goto, Narutoshi Sugita, Hiroyuki Tanaka, Tadashi Nishiyama
  • Patent number: 7846612
    Abstract: A fuel cell includes a membrane electrode assembly, and first and second separators. A first insulating bushing is attached to a first positioning hole of a first separator, and a second insulating bushing is attached to a second positioning hole of the second separator. An inner wall of the first insulating bushing is fitted to an outer wall of the second insulating bushing for positioning the first and second separators such that the first and second separators are insulated from each other.
    Type: Grant
    Filed: September 30, 2008
    Date of Patent: December 7, 2010
    Assignee: Honda Motor Co., Ltd.
    Inventors: Shuhei Goto, Katsuhiko Kohyama, Ken Takahashi, So Fujiwara, Ryugo Suzuki, Narutoshi Sugita
  • Patent number: 7842275
    Abstract: After AlH3 is synthesized, ball milling is performed under a condition in which a force of 2 G to 20 G (G represents the acceleration of gravity) is applied, to thereby provide AlH3 having an X-ray diffraction pattern in the form of a halo pattern. That is, for example, nanostructured AlH3 is provided, in which a grain boundary phase intervenes in a matrix phase, a side length t2 of the matrix phase is not more than 20 nm, and a width w2 of the grain boundary phase is not more than 10 nm. Alternatively, amorphous AlH3 may be provided. Further, hydrogen is released from AlH3 on which ball milling has been completed, and then the hydrogen is absorbed to induce a change into AlHx (provided that 0<x?3 is satisfied). A dopant may also be added. A hydrogen storage container is constructed accommodating the hydrogen absorbing material, which is obtained as described above, inside the container.
    Type: Grant
    Filed: December 14, 2007
    Date of Patent: November 30, 2010
    Assignee: Honda Motor Co., Ltd.
    Inventors: Mitsuya Hosoe, Yusuke Sogawa