Patents Represented by Attorney Marshall, Gerstein & Borun LLP
  • Patent number: 8349160
    Abstract: The present invention relates to an apparatus and method for manipulation and/or position control of particles by means of force fields of electrical nature in electrically conductive solutions, wherein power dissipated by Joule effect, which may cause the death of biological specimens under examination, is advantageously removed. The apparatus comprises a first substrate, upon which lies an array of electrodes, the application of a set of electric voltages to the electrodes generating a force field; a second substrate at a distance from, and parallel to, the first substrate so as to delimit a microchamber within which a liquid containing the particles is inserted; and cooling means for extracting an appropriate amount of heat from the microchamber, the cooling means comprising a second microchamber made in contact with, or by means of, the first or second substrate and through which a flow of cooling liquid or gas is pumped.
    Type: Grant
    Filed: October 23, 2006
    Date of Patent: January 8, 2013
    Assignee: Silicon Biosystems S.p.A.
    Inventors: Gianni Medoro, Nicolò Manaresi
  • Patent number: 8349946
    Abstract: The invention relates to a process for producing a water-absorbing resin by polymerization of a reaction mixture comprising at least one hydrophilic monomer and, if appropriate, at least one crosslinker in a reactor, which comprises admixing the reaction mixture with at least one first portion of a particulate additive before the reaction mixture has reached a residence time of 40% of the overall residence time in the reactor and with at least one second portion of a particulate additive when the reaction mixture has reached a residence time of 45% or more of the overall residence time in the reactor, the additive being selected from water-absorbing resin powders, fillers and mixtures thereof, the total solids content of monomer and additive being in the range from 30% to 60% by weight, the amount of additive being in the range from 5% to 50% by weight, based on the monomers, and the weight ratio of the first portion to the second portion of the additive being in the range from 10:1 to 1:5.
    Type: Grant
    Filed: August 23, 2010
    Date of Patent: January 8, 2013
    Assignee: BASF SE
    Inventors: Uwe Stueven, Rüdiger Funk, Matthias Weismantel, Thomas Daniel, Annemarie Hillebrecht, Dominicus van Esbroeck, Karl J. Possemiers
  • Patent number: 8350120
    Abstract: The invention is generally related to methods of generating plants transformed with novel autonomous mini-chromosomes. Mini-chromosomes with novel compositions and structures are used to transform plants cells which are in turn used to generate the plant. Methods for generating the plant include methods for delivering the mini-chromosome into plant cell to transform the cell, methods for selecting the transformed cell, and methods for isolating plants transformed with the mini-chromosome. Plants generated in the present invention contain novel genes introduced into their genome by integration into existing chromosomes.
    Type: Grant
    Filed: March 5, 2010
    Date of Patent: January 8, 2013
    Assignees: The Univesity of Chicago, Chromatin, Inc.
    Inventors: Helge Zieler, James Jin, Jennifer M Mach, Gary W Rudgers, Daphne Preuss, Mich B Hein, Gregory P Copenhaver, Kevin Keith
  • Patent number: 8349369
    Abstract: This invention relates to aqueous solutions of reactive chlorine compounds having the empirical formulae H2Cl2O6 or ClO3H, for example, and the derivatives, anions or salts thereof. The invention further relates to methods for the production of said compounds and the use thereof in the pharmaceutical and particularly in the medical field, in cosmetics, medicinal care and in the domains of food technology and technology.
    Type: Grant
    Filed: October 7, 2009
    Date of Patent: January 8, 2013
    Assignee: CytoTools GmbH
    Inventors: Klaus J. Wannowius, Dirk Kaiser
  • Patent number: 8349378
    Abstract: A brewing process including taking off a fluid having a starting temperature from a heat store; feeding the fluid to a plurality of heat consumers for releasing heat; and returning to the heat store the fluid which has a final temperature. The brewery installation has a heat store for controlling the flow of the fluid in the installation, and a plurality of heat consumers each of which is connected to the primary circuit for releasing heat. Improved efficiency is achieved in part by the final temperature of the fluid which flows out of the respective heat consumers is measured and the return of the fluid is controlled as a function of the measured final temperature.
    Type: Grant
    Filed: October 28, 2008
    Date of Patent: January 8, 2013
    Assignee: Krones AG
    Inventors: Klaus-Karl Wasmuht, Cornelia Folz
  • Patent number: 8353059
    Abstract: The present invention relates to a scanning probe (2) for capturing data from a plurality of points on the surface of an object by irradiating the object with a light stripe and detecting light reflected from the object surface, the scanning probe comprising (a) stripe generating means (14) for generating and emitting a light stripe (55); (b) a camera (16) comprising an imaging sensor having an array of pixels to detect the light stripe reflected from the object surface; (c) means for adjusting the intensity of the light stripe (55) during acquisition of the frame, in dependence upon the intensities detected by the camera (16). It also relates to a means to modify the stripe length, a scanner with separate compartment for the processing means, and an attachable dust cover for a scanner.
    Type: Grant
    Filed: July 6, 2011
    Date of Patent: January 8, 2013
    Assignee: Metris N.V.
    Inventors: Stephen James Crampton, Peter Champ
  • Patent number: 8350849
    Abstract: Interactive geographic information systems (GIS) and techniques are disclosed that provide users with a greater degree of flexibility, utility, and information. A markup language is provided that facilitates communication between servers and clients of the interactive GIS, which enables a number of GIS features, such as network links (time-based and/or view-dependent dynamic data layers), ground overlays, screen overlays, placemarks, 3D models, and stylized GIS elements, such as geometry, icons, description balloons, polygons, and labels in the viewer by which the user sees the target area. Also, “virtual tours” of user-defined paths in the context of distributed geospatial visualization is enabled. Streaming and interactive visualization of filled polygon data are also enabled thereby allowing buildings and other such features to be provided in 3D. Also, techniques for enabling ambiguous search requests in a GIS are provided.
    Type: Grant
    Filed: May 14, 2012
    Date of Patent: January 8, 2013
    Assignee: Google Inc.
    Inventors: Michael Timothy Jones, John Rohif, Brian A. McClendon
  • Patent number: 8346182
    Abstract: A radio communications system having a processing circuit, comprising a freely programmable logic control and processing receiving signals and transmission signals. The programming of the freely programmable logic control is modified in order to adjust the same to the sending operation and the receiving operation. Said modification carried out by charging and discharging the functional blocks in the freely programmable logic control via a bus system. The adjustment occurs without any interruption of the function of the radio communications system.
    Type: Grant
    Filed: March 14, 2008
    Date of Patent: January 1, 2013
    Assignee: Rohde & Schwarz GmbH & Co. KG
    Inventor: Juergen Foag
  • Patent number: 8344294
    Abstract: A method for the cooking of a cooking product in a cooking appliance with a cooking chamber that comprises at least one heating device, a computer device, a memory device and at least one sensor device, is carried out, in dependence on a degree of cooking of a cooking product and/or of a cooking duration, in particular determined by the core temperature, the browning, the pH value and/or the cooking value, from values measured by the sensor device with consideration of the at least occasionally deposited values in the memory device via the computer device, wherein at least two steps separated from one another in time, comprising a pre-cooking step, which is interrupted when a determined intermediate value of the degree of cooking and/or of the duration of cooking, in particular a determined remaining time for reaching the cooking duration is reached, and a finishing cooking step, in particular a finishing step that is recalled at a later time point in order to end the cooking of the cooking product with consi
    Type: Grant
    Filed: August 26, 2008
    Date of Patent: January 1, 2013
    Assignee: Rational AG
    Inventors: Michael Greiner, Manfred Breunig
  • Patent number: 8343748
    Abstract: Recombinant truncated human furin was expressed in CHO cells and concentrated approximately 50-fold by ultrafiltration and diafiltration. The concentrate was purified by column chromatography on CAPTO MMC™ (mixed cation exchange/hydrophobic interaction gel) resulting in a 30-50 fold purification factor and a yield of at least 60%. The at least 20% pure preparation obtained after CAPTO MMC™ (mixed cation exchange/hydrophobic interaction gel) chromatography had already a purification degree allowing on-column maturation of pro-VWF. Then an additional Arginine Sepharose chromatography purification was carried out. This two column process for purification of truncated human furin resulted in an almost pure furin preparation with a specific activity of approximately 290,000 U furin/mg protein and a yield of about 50%.
    Type: Grant
    Filed: May 21, 2008
    Date of Patent: January 1, 2013
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Peter Matthiessen, Stefan Romeder-Finger, Peter Turecek, Hans-Peter Schwarz
  • Patent number: 8343846
    Abstract: A method of forming isolation layer in a semiconductor device, comprising forming a trench on an isolation region of a semiconductor substrate by etching utilizing an isolation mask; forming a first insulating layer on a lower portion of the trench; forming a second insulating layer on the semiconductor substrate including the first insulating layer; etching the second insulating layer to increase an aspect ratio on the isolation region; and forming a third insulating layer on a peripheral region of the second insulating layer to fill moats formed on the second insulating layer with the third insulating layer.
    Type: Grant
    Filed: June 2, 2008
    Date of Patent: January 1, 2013
    Inventor: Cha Deok Dong
  • Patent number: 8342033
    Abstract: The invention relates to a method for monitoring the bending of a shaft, particularly a shaft in a mixing kneader, the shaft having a bearing at least on one side. In a first step, the deviation of the shaft from the radial position is measured on at least one position different from the bearing of the shaft. In a further step, a reference value is optionally determined from the measured deviation from the radial position. In a third step, the deviation from the radial position as measured in the first step or the reference value found in the second step is compared with a predetermined limit value.
    Type: Grant
    Filed: June 10, 2008
    Date of Patent: January 1, 2013
    Assignee: BASF SE
    Inventors: Huanmin Wei, Wilfried Heide, Annemarie Hillebrecht, Oskar Stephan, Asif Karim
  • Patent number: 8347411
    Abstract: The scanning probe microscope has a primary control loop (7, 11, 12) for keeping the phase and/or amplitude of deflection at constant values as well as a secondary control loop (9) that e.g. keeps the frequency of the cantilever oscillation constant by applying a suitable DC voltage to the probe while, at the same time, a conservative AC excitation is applied thereto. By actively controlling the frequency with the first control loop (7, 11, 12) and subsequently controlling the DC voltage in order to keep the frequency constant, a fast system is created that allows to determine the contact potential difference or a related property of the sample (3) quickly.
    Type: Grant
    Filed: July 14, 2006
    Date of Patent: January 1, 2013
    Assignee: Specs Zürich GmbH
    Inventors: Dominik Ziegler, Andreas Christian Stemmer, Jorg Rychen
  • Patent number: 8343512
    Abstract: Compositions and methods, including vaccines and pharmaceutical compositions for inducing or enhancing an immune response are disclosed based on the discovery of useful immunological adjuvant properties in a synthetic, glucopyranosyl lipid adjuvant (GLA) that is provided in substantially homogeneous form. Chemically defined, synthetic GLA offers a consistent vaccine component from lot to lot without the fluctuations in contaminants or activity that compromise natural-product adjuvants. Also provided are vaccines and pharmaceutical compositions that include GLA and one or more of an antigen, a Toll-like receptor (TLR) agonist, a co-adjuvant and a carrier such as a pharmaceutical carrier.
    Type: Grant
    Filed: October 20, 2011
    Date of Patent: January 1, 2013
    Assignee: Infectious Disease Research Institute
    Inventors: Steven G. Reed, Darrick Carter
  • Patent number: 8343797
    Abstract: A process for preparing a solar cell comprising a support, a layer of cadmium sulfide (CdS), a layer of cadmium telluride (CdTe), a layer of a transparent conductive oxide (TCO), a conductive metallic layer and optionally a layer of buffer material, the CdS layer and the CdTe layer being deposited by means of a pulsed plasma deposition (PPD) method, a solar cell obtainable by means of the described process being also provided.
    Type: Grant
    Filed: September 17, 2008
    Date of Patent: January 1, 2013
    Inventors: Carlo Taliani, Petr Nozar
  • Patent number: 8343500
    Abstract: There is provided a method for selecting a tolerogenic peptide by selecting a peptide which is capable of binding to an MHC class I or II molecule without further processing. There is also provided a peptide selected by such a method and its use in a pharmaceutical composition and a method to treat and/or prevent a disease. The present invention also relates to a composition which comprises the following myelin basic protein (MBP) peptides: MBP 30-44; MBP 83-99; MBP 131-145; and MBP 140-154. The composition may be used to treat a disease, in particular multiple sclerosis and/or optical neuritis and the invention also relates to such uses and methods.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: January 1, 2013
    Assignee: Apitope Technology (Bristol) Limited
    Inventors: David Cameron Wraith, Heather Barbara Streeter
  • Patent number: 8343503
    Abstract: Contiguous overlapping peptides (COPs) for the treatment of allergic patients by Specific Immunotherapy (SIT) are provided from the sequence of the major allergen of birch pollen Bet v 1. Such peptides while providing all potential T cell epitopes are devoid of the 3D structure of the original allergen, therefore reducing their ability to bind IgE.
    Type: Grant
    Filed: February 9, 2010
    Date of Patent: January 1, 2013
    Assignee: Anergis S.A.
    Inventors: Christophe Reymond, Francois Spertini
  • Patent number: 8344110
    Abstract: The present invention provides Thymic Stromal Lymphopoietin Receptor (TSLPR) polypeptides and nucleic acid molecules encoding the same. The invention also provides selective binding agents, vectors, host cells, and methods for producing TSLPR polypeptides. The invention further provides pharmaceutical compositions and methods for the diagnosis, treatment, amelioration, and/or prevention of diseases, disorders, and conditions associated with TSLPR polypeptides.
    Type: Grant
    Filed: June 8, 2011
    Date of Patent: January 1, 2013
    Assignee: Amgen Inc.
    Inventors: Christiaan M Saris, Ming-Shi Chang
  • Patent number: 8336574
    Abstract: A regulator comprises a regulator valve and an actuator. The actuator is coupled to the regulator valve and comprises a control element for controlling the flow of fluid through the regulator valve. The actuator is additionally equipped with a pressure averaging sense tube to sense the actual pressure at the outlet of the regulator valve. The actual pressure is then supplied to a sensing element such as a diaphragm of the actuator to adjust the position of the control element. The pressure averaging sense tube includes an open sensing end and an elongated slot. The elongated slot advantageously senses and averages the pressure across the length of the sense tube to maximize the accuracy of the pressure signal supplied to the sensing element.
    Type: Grant
    Filed: April 8, 2008
    Date of Patent: December 25, 2012
    Assignee: Fisher Controls International LLC
    Inventors: Seth Kranz, Joseph Losh
  • Patent number: D673934
    Type: Grant
    Filed: December 6, 2011
    Date of Patent: January 8, 2013
    Assignee: KT Corporation
    Inventors: Tae-Ho Shin, Young-Lyoul Lee, Jang-Mi Lim, Jun-Ryul Choi