Abstract: A method for the radioimmunoassay of PGE.sub.1 -type and PGE.sub.2 -type compounds and PGX is disclosed which utilizes antibodies formed against a prostaglandin mimic.Conjugates are disclosed which are formed by attaching a prostaglandin mimic to a carrier molecule.Antibodies are disclosed which are specific against PGE.sub.1 -type and PGE.sub.2 -type compounds, PGH.sub.2, and PGX.Complexes are disclosed which are formed by binding an antibody raised against a prostaglandin mimic with its corresponding authentic prostaglandin.

Abstract: Compounds of the formula ##STR1## where R.sub.4 X is a polycyclocoupled group and R.sub.1 and R.sub.2 are H or simple hydrocarbon and R.sub.3 has the same value and additionally simple acyl, can be made by a variety of syntheses. They have hypolipedemic and antiatherosclerotic properties, and are useful in that field.

Abstract: Some known 4-amino-6-chloro-5-(H or CH.sub.3)-2-(methylthio or methoxy)pyrimidines have been found to be active against fungi. The compounds are systemically active in plants, that is to say, the compounds are carried by plant juices to sites of infection. Other related compounds that are novel have the same activity and advantage. The compounds are prepared according to well-known methods. A new method and formulations for killing and controlling fungi are described.

Abstract: A method for the radioimmunoassay of PGE.sub.1 -type and PGE.sub.2 -type compounds and PGX is disclosed which utilizes antibodies formed against a prostaglandin mimic.Conjugates are disclosed which are formed by attaching a prostaglandin mimic to a carrier molecule.Antibodies are disclosed which are specific against PGE.sub.1 -type and PGE.sub.2 -type compounds, PGH.sub.2, and PGX.Complexes are disclosed which are formed by binding an antibody raised against a prostaglandin mimic with its corresponding authentic prostaglandin.

Abstract: Compounds represented below ##STR1## and pharmaceutical compositions thereof, the compositions including the non-substituted phenylene dioxamates are useful in the prophylactic treatment of sensitized mammals for allergy and all anaphylactic reactions of a reagin or non-reagin mediated nature.

Abstract: Compounds of the formula below are useful for expanding the lumina or air passages in a mammal in need of said treatment. The compounds are also useful for treating atopic eczema and urticaria. ##STR1## wherein X and Y are the same or different and are hydrogen, fluoro, chloro, bromo, nitro, trifluoromethyl, alkyl of one to four carbon atoms, inclusive, alkoxy of one to four carbon atoms, inclusive, and cyano;R.sub.1 is hydrogen, methyl or ethyl;R.sub.2 is hydrogen, alkyl of one to six carbon atoms, inclusive, phenyl, benzyl,CH.sub.2 Z wherein Z is fluoro, chloro, or bromo,CO.sub.2 M, CH.sub.2 CO.sub.2 M, CH.sub.2 CH.sub.2 CO.sub.2 M and CHR.sub.3 CO.sub.2 M wherein M is hydrogen, alkyl of one to four carbon atoms, inclusive, or a physiologically acceptable metal or amine cation and R.sub.3 is alkyl of one to three carbon atoms, inclusive, with the proviso that M is not hydrogen when R.sub.2 is CH.sub.2 CO.sub.2 M or a CHR.sub.3 CO.sub.2 M.

Abstract: Novel compounds of the formula ##STR1## wherein R is alkyl of one to eight carbon atoms, inclusive, are formulated into pharmaceutical compositions suitable for oral or parenteral administration which are used as agents to prophylactically inhibit the allergic manifestations of a sensitized mammal.

Abstract: It has now been discovered that compounds of FIG. I ##STR1## are useful in the prophylactic treatment of sensitized humans and animals for allergy and all anaphylactic reactions of a reagin or non-reagin mediated nature. The compounds are formulated with pharmaceutical carriers for oral, parenteral, inhalation, or rectal means of administration. Certain compounds are novel.

Abstract: Compounds represented below ##STR1## and pharmaceutical compositions thereof, the compositions including the non-substituted phenylene dioxamates are useful in the prophylactic treatment of sensitized mammals for allergy and all anaphylactic reactions of a reagin or non-reagin mediated nature.

Abstract: Compounds, compositions and methods of using the compounds of the formula as anti-allergics ##STR1## wherein X' is the same as X, X' is at the 3 or 4 position and is ##STR2## R is selected from the group consisting of hydrogen alkyl of one to eight carbon atoms, inclusive, and a physiologically acceptable metal or amine cation;R.sub.1 and R.sub.2 are the same or different and are selected from the group consisting of hydrogen, alkyl of one to six carbon atoms, inclusive, alkoxy of one to six carbon atoms, inclusive, phenyl, cyano, nitro, trifluoromethyl, fluoro, chloro, and bromo, with the proviso that one of R.sub.1 and R.sub.2 is other than hydrogen.

Abstract: A method of treating mammals for allergy and anaphylactic reactions of a reagin or non-reagin mediated nature which comprises administering prophylactically to said mammal an anti-allergy or anaphylactic reaction effective amount of a compound of the formula ##STR1## Novel compositions are also claimed.

Abstract: A method of treating mammals for allergy and anaphylactic reactions of a reagin or non-reagin mediated nature which comprises administering prophylactically to said mammal an anti-allergy or anaphylactic reaction effective amount of a compound of the formula ##STR1## Novel compositions are also claimed.

Abstract: Compounds of the formula ##STR1## wherein X and Y are the same or different and are hydrogen, fluoro, chloro, bromo, alkyl of one to six carbon atoms, inclusive, alkoxy of one to six carbon atoms, inclusive, nitro, cyano, amino, trifluoromethyl, ##STR2## wherein R.sub.1 is alkyl of one to six carbon atoms, inclusive, ##STR3## wherein R.sub.2 and R.sub.3 are the same or different and are hydrogen or alkyl of one to three carbon atoms inclusive, or CO.sub.2 Q where Q is alkyl of one to six carbon atoms, inclusive, hydrogen or a physiologically acceptable metal or amine cation; andR is hydrogen, alkyl of one to eight carbon atoms, inclusive, --CH.sub.2).sub.m phenyl wherein m is 0, 1 or 2 or (CH.sub.2).sub.n NR.sub.4 R.sub.5 wherein n is 1 or 2, and R.sub.4 and R.sub.

Abstract: Novel 4-amino-cyclohexan-1-ols are formulated into pharmaceutical compositions for the relief of pain in mammals in need of said treatment.

Abstract: Compounds of the formula ##STR1## where R.sub.4 X is a polycyclocoupled group and R.sub.1 and R.sub.2 are H or simple hydrocarbon and R.sub.3 has the same value and additionally simple acyl, can be made by a variety of syntheses. They have hypolipedemic and antiatherosclerotic properties, and are useful in that field.

Abstract: A method of treating mammals for allergy and anaphylactic reactions of a reagin or non-reagin mediated nature which comprises administering prophylactically to said mammal an anti-allergy or anaphylactic reaction effective amount of a compound of the formula ##STR1## Novel compounds and compositions are also claimed.

Abstract: Pharmaceutical composition having as the active agent a compound of the formula ##STR1## wherein R is hydrogen, a physiologically acceptable metal or amine cation and alkyl of one to eight carbon atoms inclusive, useful for preventing allergic manifestations in sensitized mammals.

Abstract: Novel chemical compounds of the formula: ##STR1## wherein R is selected from the group consisting of hydrogen, alkyl from one to three carbon atoms, inclusive, phenyl, alkali metal, or an amine cation;X and Y can be the same or different and are selected from the group consisting of hydrogen, alkyl or from one to six carbon atoms, inclusive, cycloalkyl of 5 or 6 carbon atoms, inclusive, phenyl, hydroxyl, alkoxy having from one to three carbon atoms, inclusive, halogen, trifluoromethyl, cyano, carboxyamide and ##STR2## where Q is selected from the group consisting of hydrogen, alkyl from one to three carbon atoms, inclusive, alkali metal, and an amine cation, with the proviso that whereR is hydrogen, alkali metal or an amine cation, then Q is the same as R, and whereR is phenyl or alkyl from one to three carbon atoms, then Q is phenyl or alkyl from one to three carbon atoms; andZ is selected from the group consisting of hydrogen, alkyl from one to three carbon atoms, inclusive, and phenyl.

Abstract: Some new 4-amino-2-lower-alkyl-6-variable-pyridine-1-oxides are described. A new process is provided. The 6-variable is lower-alkyl, amino or substituted amino including saturated heterocyclic amino, e.g., pyrrolidinyl, piperidino, etc. The compounds are hypotensive agents and reduce blood pressure in animals.

Abstract: Compounds of the formula ##STR1## where R.sub.4 X is a polycyclocoupled group and R.sub.1 and R.sub.2 are H or simple hydrocarbon and R.sub.3 has the same value and additionally simple acyl, can be made by a variety of syntheses. They have hypolipedemic and antiatherosclerotic properties, and are useful in that field.