Patents Represented by Attorney Martin B. Barancik
  • Patent number: 4288542
    Abstract: A new radioenzymatic assay for catecholamines utilizing the catechol-O-methyl transferase transfer of a methyl group from a labeled methyl donor to the catecholamines followed by isolation of the O-methylated (.sup.3 H)catecholamine and the subsequent measurement of radioactivity.
    Type: Grant
    Filed: August 8, 1978
    Date of Patent: September 8, 1981
    Assignee: The Upjohn Company
    Inventors: Garland A. Johnson, Jacob D. Peuler
  • Patent number: 4287368
    Abstract: A new radioenzymatic assay for catecholamines utilizing the catechol-0-methyl transferase transfer of a methyl group from a labeled methyl donor to the catecholamines followed by isolation of the 0-methylated(.sup.3 H)catecholamine and the subsequent measurement of radioactivity.
    Type: Grant
    Filed: February 26, 1980
    Date of Patent: September 1, 1981
    Assignee: The Upjohn Company
    Inventors: Garland A. Johnson, Jacob D. Peuler
  • Patent number: 4286085
    Abstract: An interfacial polymerization process for preparing a high molecular weight aromatic carbonate polymer by reacting a dihydric phenol with a carbonate precursor in the presence of a catalytic amount of a substituted pyridine or a salt of a substituted pyridine.
    Type: Grant
    Filed: December 28, 1979
    Date of Patent: August 25, 1981
    Assignee: General Electric Company
    Inventors: Donald B. G. Jaquiss, Victor Mark, Lawrence C. Mitchell
  • Patent number: 4286086
    Abstract: An interfacial polymerization process for preparing high molecular weight aromatic polycarbonates by reacting a dihydric phenol with a carbonate precursor in the presence of a catalytic amount of certain sterically hindered secondary amines or their salts.
    Type: Grant
    Filed: December 28, 1979
    Date of Patent: August 25, 1981
    Assignee: General Electric Company
    Inventor: Victor Mark
  • Patent number: 4286084
    Abstract: An interfacial polymerization process for preparing high molecular weight aromatic polycarbonates by reacting a dihydric phenol with a carbonate precursor in the presence of a catalytic amount of a 5 to 8 membered heterocyclic compound which contains only carbon and nitrogen atoms in the ring and further characterized in that the ring contains at least two nitrogen atoms and at least one carbon atom, and in that the ring is aromatic in character and contains a maximum amount of olefinic unsaturation.
    Type: Grant
    Filed: December 28, 1979
    Date of Patent: August 25, 1981
    Assignee: General Electric Company
    Inventor: Victor Mark
  • Patent number: 4284587
    Abstract: A new radioenzymatic assay for catecholamines utilizing the catechol-O-methyl transferase transfer of a methyl group from a labeled methyl donor to the catecholamines followed by isolation of the O-methylated(.sup.3 H)catecholamine and the subsequent measurement of radioactivity.
    Type: Grant
    Filed: October 12, 1978
    Date of Patent: August 18, 1981
    Assignee: The Upjohn Company
    Inventors: Garland A. Johnson, Jacob D. Peuler
  • Patent number: 4283566
    Abstract: An improved process for obtaining halogenated diphenols which can be pure dihalodiphenols or predetermined, statistical mixtures comprising unreacted diphenol, monohalodiphenols and dihalodiphenols.
    Type: Grant
    Filed: January 21, 1980
    Date of Patent: August 11, 1981
    Assignee: General Electric Company
    Inventor: Victor Mark
  • Patent number: 4282134
    Abstract: A plasticized polycarbonate composition comprising in admixture a high molecular weight aromatic carbonate polymer and a minor amount of an organic plasticizer, said organic plasticizer being represented by the following general formula: ##STR1## wherein R and R.sub.1 are independently selected from the group consisting of C.sub.1 to C.sub.30 alkyl, aryl of 6 to 14 carbon atoms and substituted aryl wherein the substituents on said substituted aryl are C.sub.1 to C.sub.30 alkyl, halogen, C.sub.1 to C.sub.30 alkoxy, aryloxy of 6 to 14 carbon atoms, alkylthio of 1 to 30 carbon atoms and arylthio of 6 to 14 carbon atoms; R.sub.2 is C.sub.1 to C.sub.30 alkylene, arylene of 6 to 14 carbon atoms, alkarylene of 7 to 30 carbon atoms, aralkylene of 7 to 30 carbon atoms and ##STR2## wherein W is selected from the group consisting of: (a) --O--;(b) --S--; ##STR3## wherein X and Y are independently selected from the group consisting of halogen and C.sub.1 to C.sub.12 alkyl.
    Type: Grant
    Filed: May 9, 1979
    Date of Patent: August 4, 1981
    Assignee: General Electric Company
    Inventors: Victor Mark, Phillip S. Wilson
  • Patent number: 4281151
    Abstract: Compounds represented below ##STR1## and pharmaceutical compositions thereof, the compositions including the non-substituted phenylene dioxamates are useful in the prophylactic treatment of sensitized mammals for allergy and all anaphylactic reactions of a reagin or non-reagin mediated nature.
    Type: Grant
    Filed: June 2, 1978
    Date of Patent: July 28, 1981
    Assignee: The Upjohn Company
    Inventors: Charles M. Hall, John B. Wright
  • Patent number: 4277600
    Abstract: Novel tetraphenolic compounds are disclosed. These compounds have utility as branching agents in the production of novel, randomly branched polycarbonates.
    Type: Grant
    Filed: September 20, 1979
    Date of Patent: July 7, 1981
    Assignee: General Electric Company
    Inventors: Victor Mark, Charles V. Hedges
  • Patent number: 4277597
    Abstract: An interfacial polymerization process for preparing high molecular weight polycarbonates by reacting a dihydric phenol with a carbonate precursor in the presence of a catalytic amount of a sterically hindered heterocycloaliphatic secondary amine or a salt thereof.
    Type: Grant
    Filed: December 28, 1979
    Date of Patent: July 7, 1981
    Assignee: General Electric Company
    Inventor: Victor Mark
  • Patent number: 4277598
    Abstract: An interfacial polymerization process for preparing high molecular weight aromatic polycarbonates by reacting a dihydric phenol with a carbonate precursor in the presence of a catalytic amount of a cyclic amidine.
    Type: Grant
    Filed: December 28, 1979
    Date of Patent: July 7, 1981
    Assignee: General Electric Company
    Inventors: Walter L. Hall, Donald B. G. Jaquiss, Victor Mark
  • Patent number: 4277599
    Abstract: An interfacial polymerization process for preparing a high molecular weight aromatic carbonate polymer by reacting a dihydric phenol with a carbonate precursor in the presence of a catalytic amount of a compound selected from pyrroles and pyrrole salts.
    Type: Grant
    Filed: December 28, 1979
    Date of Patent: July 7, 1981
    Assignee: General Electric Company
    Inventor: Victor Mark
  • Patent number: 4276233
    Abstract: Thermally stable polycarbonate compositions are obtained by admixing with a high molecular weight aromatic polycarbonate resin a stabilizing amount of a hindered phenol phosphite.
    Type: Grant
    Filed: July 16, 1979
    Date of Patent: June 30, 1981
    Assignee: General Electric Company
    Inventors: Ronald L. Markezich, Walter K. Olander, Robert J. Axelrod
  • Patent number: 4275187
    Abstract: A continuous process for obtaining highly pure, high molecular weight aromatic polycarbonates from highly pure, halogenated diphenols.
    Type: Grant
    Filed: December 10, 1979
    Date of Patent: June 23, 1981
    Assignee: General Electric Company
    Inventors: Clayton B. Quinn, Charles A. Wilson, II
  • Patent number: 4262123
    Abstract: Compounds of the formula below are useful for expanding the lumina of air passages in a mammal in need of said treatment. The compounds are also useful for treating atopic eczema and urticaria. ##STR1## wherein X and Y are the same or different and are hydrogen, fluoro, chloro, bromo, nitro, trifluoromethyl, alkyl of one to four carbon atoms, inclusive, alkoxy of one to four carbon atoms, inclusive, and cyano;R.sub.1 is hydrogen, methyl or ethyl;R.sub.2 is hydrogen, alkyl of one to six carbon atoms, inclusive, phenyl, benzyl,CH.sub.2 Z wherein Z is fluoro, chloro, or bromo,CO.sub.2 M, CH.sub.2 CO.sub.2 M, CH.sub.2 CH.sub.2 CO.sub.2 M and CHR.sub.3 CO.sub.2 M wherein M is hydrogen, alkyl of one to four carbon atoms, inclusive, or a physiologically acceptable metal or amine cation and R is alkyl of one to three carbon atoms, inclusive, with the proviso that M is not hydrogen when R.sub.2 is CH.sub.2 CO.sub.2 M or CHR.sub.3 CO.sub.2 M.
    Type: Grant
    Filed: May 31, 1979
    Date of Patent: April 14, 1981
    Assignee: The Upjohn Company
    Inventors: Charles M. Hall, Herbert G. Johnson
  • Patent number: 4252813
    Abstract: Compounds of the formula ##STR1## are useful as anti-allergy agents.
    Type: Grant
    Filed: November 19, 1979
    Date of Patent: February 24, 1981
    Assignee: The Upjohn Company
    Inventor: John B. Wright
  • Patent number: 4242222
    Abstract: A new radioenzymatic assay for catecholamines utilizing the catechol-O-methyl transferase transfer of a methyl group from a labeled methyl donor to the catecholamines followed by isolation of the O-methylated(.sup.3 H)catecholamine and the subsequent measurement of radioactivity.
    Type: Grant
    Filed: October 12, 1978
    Date of Patent: December 30, 1980
    Assignee: The Upjohn Company
    Inventors: Garland A. Johnson, Jacob D. Peuler
  • Patent number: 4242342
    Abstract: Compounds of the formula below are useful for expanding the lumina of air passages in a mammal in need of said treatment. The compounds are also useful for treating atopic eczema and urticaria. ##STR1## wherein X and Y are the same or different and are hydrogen, fluoro, chloro, bromo, nitro, trifluoromethyl, alkyl of one to four carbon atoms, inclusive, alkoxy of one to four carbon atoms, inclusive, and cyano;R.sub.1 is hydrogen, methyl or ethyl;R.sub.2 is hydrogen, alkyl of one to six carbon atoms, inclusive, phenyl, benzyl,CH.sub.2 Z wherein Z is fluoro, chloro, or bromo,CO.sub.2 M, CH.sub.2 CO.sub.2 M, CH.sub.2 CH.sub.2 CO.sub.2 M and CHR.sub.3 CO.sub.2 M wherein M is hydrogen, alkyl of one to four carbon atoms, inclusive, or a physiologically acceptable metal or amine cation and R.sub.3 is alkyl of one to three carbon atoms, inclusive, with the proviso that M is not hydrogen when R.sub.2 is CH.sub.2 CO.sub.2 M or CHR.sub.3 CO.sub.2 M.
    Type: Grant
    Filed: May 31, 1979
    Date of Patent: December 30, 1980
    Assignee: The Upjohn Company
    Inventors: Charles M. Hall, Herbert G. Johnson
  • Patent number: 4242456
    Abstract: A new radioenzymatic assay for catecholamines utilizing the catechol-O-methyl transferase transfer of a methyl group from a labeled methyl donor to the catecholamines followed by isolation of the O-methylated(.sup.3 H)catecholamine and the subsequent measurement of radioactivity.
    Type: Grant
    Filed: October 12, 1978
    Date of Patent: December 30, 1980
    Assignee: The Upjohn Company
    Inventors: Garland A. Johnson, Jacob D. Peuler