Abstract: An acidic aqueous coating composition comprising dissolved phosphate, dissolved aluminum, dissolved dichromate, inorganic colloidal particles and a water miscible organic component including an effective film-forming amount of a water miscible material comprising an ether of a polypropylene glycol, and preferably including also another glycol material, for example, a mono-ethylene glycol material or a monopropylene glycol material, for use as a glaze coating, or as a base coating which includes also a particulate material.
Abstract: Process and system for the preparation of a low viscosity Aluminum Hydroxy Carbonate Gel having viscosity-resistant properties and a predetermined alkali ion content, comprising reacting under constant pH conditions an aqueous carbonate solution and an aqueous aluminum salt solution to form a reaction product, equilibrating the reaction product at naturally occurring pH and washing the equilibrated reaction product to provide the predetermined alkali ion content and the gel product by same processes.
Abstract: A jigsaw message pad comprising a removable sheet of interlocked jigsaw pieces which is within a sleeve characterized bu an open end through which said sheet may be removed and a window through which one surface of said sheet can be viewed.
Abstract: A class of bicyclic benzo-oxy heterocyclic ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastro-intestinal hyperacidity and ulcerogenic disorders in mammals using said compositions.
Type:
Grant
Filed:
October 23, 1984
Date of Patent:
September 16, 1986
Assignee:
William H. Rorer, Inc.
Inventors:
Donald E. Kuhla, Henry F. Campbell, William L. Studt, Kent W. Neuenschwander
Abstract: This invention relates to an improvement comprising coating agitated particles of substantially anhydrous antacid with a solvent-free mixture of electronegatively charged material in a non-toxic inert substantially water insoluble oil.
Type:
Grant
Filed:
November 30, 1984
Date of Patent:
August 12, 1986
Assignee:
William H. Rorer, Inc.
Inventors:
John D. Buehler, Hans J. Medal, Gregory A. Rhoa
Abstract: A class of 3- and 5-amino thiatriazine compounds exhibiting pharmacological activity, including gastrointestinal anti-ulcerogenic and cytoprotective activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity and ulcerogenic disorders in mammals using said compositions.
Type:
Grant
Filed:
October 23, 1984
Date of Patent:
June 17, 1986
Assignee:
William H. Rorer, Inc.
Inventors:
Donald E. Kuhla, Henry F. Campbell, William L. Studt, Stuart A. Dodson
Abstract: Cardiotonic 5-heteroaryl-substituted-2-pyridone compounds, pharamaceutical compositions, and a method for the treatment of congestive heart failure.
Abstract: A class of bicyclic benzenoid aminoalkylene ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity and ulcerogenic disorders in mammals using said compositions.
Type:
Grant
Filed:
October 24, 1984
Date of Patent:
May 13, 1986
Assignee:
William H. Rorer, Inc.
Inventors:
William L. Studt, Donald E. Kuhla, Henry F. Campbell
Abstract: This invention relates to a novel class of heterocyclic amidinourea and heterocyclic amidinothiourea compounds wherein the heterocyclic substitution is at the 1-N urea nitrogen atom. These compounds exhibit pharmaceutical activity and may be incorporated into pharmaceutical preparations for producing anti-ulcerogenic, antisecretory, antispasmodic, antimotility, cardiovascular, antidiarrheal or antiparasitic action.
Type:
Grant
Filed:
February 24, 1984
Date of Patent:
January 21, 1986
Assignee:
William H. Rorer, Inc.
Inventors:
William L. Studt, Harry K. Zimmerman, George H. Douglas
Abstract: A method of inducing blood pressure reduction in humans and mammals by administering 2,6-disubstituted phenyl N-alkyl amidinoureas in which the phenyl ring is additionally substituted by a hydroxy, alkoxy, aralkoxy, alkenyloxy, alkynyloxy, acyloxy or halo acyloxy group and a novel class of amidinourea compounds having pharmaceutical uses, including blood pressure lowering activity.
Type:
Grant
Filed:
February 2, 1984
Date of Patent:
January 14, 1986
Assignee:
William H. Rorer, Inc.
Inventors:
William L. Studt, Richard L. Riley, George H. Douglas
Abstract: A method for the treatment of irritable bowel syndrome using a 1,3,5-triazin-2-one and a class of 6-amino and 6-mercaptyl-1,3,5-triazin-2-one compounds.
Type:
Grant
Filed:
January 13, 1984
Date of Patent:
December 31, 1985
Assignee:
William H. Rorer, Inc.
Inventors:
Donald E. Kuhla, William L. Studt, Henry F. Campbell, John Yelnosky
Abstract: Feed supplements, which increase the dwell time of ingested nutrient matter in the gastrointestinal tract of food producing animals, and which provide for increased digestion and absorption of ingested nutrient matter, are administered to food producing animals to increase feed efficiency.
Abstract: Methods for the treatment of physiological disorders, including protozoal infections in mammalian and avian species and gastrointestinal and cardiovascular disorders in mammalian species by administering a class of aralkyl- and aralkenyl-acyl, and thioacyl, guanidine compounds, pharmaceutical compositions containing such compounds for systemic administration, and a class of novel aralkenyl-, aryl-substituted cycloalkyl-, and arylsubstituted heterocycle-acyl and thioacyl guanidines.
Type:
Grant
Filed:
August 24, 1982
Date of Patent:
October 1, 1985
Assignee:
William H. Rorer, Inc.
Inventors:
William L. Studt, Stuart A. Dodson, Harry K. Zimmerman, James L. Barnes
Abstract: A class of naphthalene aminoalkylene ether and thioether compounds exhibiting pharmacological activity including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity and ulcerogenic disorders in mammals using said compositions are disclosed.
Type:
Grant
Filed:
April 29, 1983
Date of Patent:
September 24, 1985
Assignee:
William H. Rorer, Inc.
Inventors:
Donald E. Kuhla, Henry F. Campbell, William L. Studt
Abstract: 5-Diaza-aryl-3-substituted-2-pyridone compounds useful for increasing cardiac contractility, pharmaceutical compositions and a method for the treatment of congestive heart failure comprising the use of said compounds.
Abstract: A class of bicyclic benzenoid aminoalkylene ether and thioether compounds exhibiting pharmacological activity including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity and ulcerogenic disorders in mammals using said compositions are disclosed.
Type:
Grant
Filed:
April 29, 1983
Date of Patent:
July 16, 1985
Assignee:
William H. Rorer, Inc.
Inventors:
Donald E. Kuhla, Henry F. Campbell, William L. Studt