Abstract: The present invention provides a new compound which shows slow and continuous blood pressure reducing action and is useful as an antihypertensive agent.
The invention resides in a quinazoline derivative of the following formula (I) and its pharmaceutically acceptable salt:
in which, each of R1 and R2 is H or an alkyl group of 1 to 6 carbon atoms, or R1 and R2 are combined to form an ethylene group; each of R3 and R4 is an alkyl group of 1 to 6 carbon atoms; R5 is a hydrogen atom, a hydroxyl group, an alkyl group of 1 to 6 carbon atoms, or an alkoxy group of 1 to 6 carbon atoms; each of R6 and R7 is a hydrogen atom or an alkyl group of 1 to 6 carbon atoms; and n is 2 or 3. The invention further resides in an antihypertensive agent containing the above compound.
Abstract: A hydrodynamic bearing apparatus comprises two hydrodynamic bearing sections which have a shaft member, a bearing member fit to the shaft member with a predetermined space therein, lubricants filling the space between the shaft member and the bearing member, and which are separately placed in the axial direction of the shaft member. The lubricants of the two hydrodynamic bearing sections are separated from each other by an air layer. The lubricants are pressured by hydrodynamic generating grooves formed on the hydrodynamic bearing sections such that the shaft member and the bearing member are rotatably supported in relation to each other. The hydrodynamic generating grooves separately formed on the two hydrodynamic bearing sections are formed into an unbalanced shape such that the lubricants are moved in a predetermined direction to correct the slope of the shaft member and the bearing member when rotation is suspended.
Abstract: A dynamic-pressure fluid bearing comprises bearing parts formed by a pair of dynamic-pressure surfaces. One of the dynamic-pressure surfaces of the bearing parts is a polyamideimide coating thicker than 3 .mu.m and the other surface is metal. The bearing is particularly applicable to driving motors for polygon mirrors. In addition, a so-called particle removing function is added to one or more of the surfaces of the bearing parts or a position nearby that causes easier removal of dust and other particles accumulated on the parts.
Abstract: Described is an adhesive containing a polycarbodiimide resin having repeating units represented by the following formula:.paren open-st.R--N.dbd.C.dbd.N.paren close-st..sub.nwherein R is a divalent hydrocarbon group and n is an integer of 5 to 250, and also described is a flexible printed circuit board and a coverlay film fabricated using the above-described polycarbodiimide resin-containing adhesive.
Abstract: A method for target seeking in geodetic survey measurements comprises the steps of generating at least a first light bundle by a measurement device from a light source arranged therein, the light bundle periodically pivoting back and forth or revolving about the standing axis of the measurement device and fanning out in the vertical plane and being sent to at least one receiver arrangement arranged in at least one target station arranged at a distance from the measurement device.
July 30, 1998
Date of Patent:
October 17, 2000
Carl Zeiss Jena GmbH
Ludwin-Heinz Monz, Bernd Donath, Hermann Goering, Steffen Laabs, Thomas Marold, Marcel Seeber
Abstract: The blood collecting syringe is constructed for coupling with an arterial blood sampling system. In one embodiment, upon retraction of a plunger, a collapsed hollow deformable stopper expands to draw any air bubble and fluid into a small discard chamber within the stopper. Continued retraction of the plunger causes the stopper to also retract thereby forming a specimen collecting chamber within the distal end of the barrel for receiving whole blood from the sampling system. In another embodiment, the plunger has a cap mounted within a hollow stopper so that upon movement of the cap from a forward position within the stopper to a retracted position within the stopper, a discard chamber is formed within the stopper while at the same time, any air bubble and fluid is drawn into the discard chamber. Subsequent movement of the plunger also causes retraction of the nozzle thereby opening up a blood specimen collecting chamber.
Abstract: A gold material for accessories comprises a hardened gold alloy composed of pure gold having a purity of 99% or more and from 200 to 2000 ppm, relative to the total weight of the resulting gold alloy, of one or more alloying components selected from Ca, Be, Ge and B, and optionally from 10 to 500 ppm, relative to the same, of one or more other alloying components selected from Mg, Al, Si, Mn, Fe, Co, Ni, Cu, Pd, Ag, In, Sn, Sb, Pb and Bi and/or from 10 to 1000 ppm, relative to the same, of one or more other alloying components selected from rare earth elements including Y.
Abstract: To provide a compact size machine tool free from the inconveniences inherent to the prior art and excellent in the collection and removal of chips or the like, there is provided a channel 39 in a central portion of the bed 3 directly beneath the table 21 and extending parallel to the table moving direction; a chip conveyor 47 being provided inside the channel 39; on both sides with respect to the channel 39, a pair of opposite slopes 51, 51 for collection of chips as well as telescopic covers 53, 53 extensible or contractible in accordance with the displacement of the table 21 being provided so as to cover a pair of guide rails 13, 13 which extend parallel to each other along the Z direction.
Abstract: A stabilizing agent for peroxide-bleaching procedure includes (A) a component including a homopolymer or copolymer of .alpha.-hydroxyacrylic acid or water soluble salt or polylactone of the homo- or co-polymer, (B) a component including a homopolymer or copolymer of acrylic acid, methacrylic acid and/or maleic acid and water-soluble salt of the homo- or co-polymer, (C) a component including DTPA, TTHA or water-soluble salt thereof and optionally (D) a component including a water-soluble inorganic Mg salt and is used to pretreat a fiber material with a pretreating liquid containing the stabilizing agent before bleaching with peroxide, or to bleach the fiber material by a bleaching liquid containing a peroxide bleaching agent and the stabilizing agent.
Abstract: A device is provided for reducing noise in the human ear having a microphone which picks up the noise and a reproduction transducer to which a noise compensation signal is fed via a compensation circuit which is connected with the microphone. The microphone in the device has a balancing element which is arranged in front of the sound entrance opening of the microphone. The balancing element defines a quasi-constant sound reflection and accordingly reduces individual reflection effects caused by the fundamental diversity of the external region of the human ear and improves the use of the entire device and increases the effectiveness of the noise compensation overall. In this way, headphones/hearing protectors can also be designed as acoustically closed systems which are designed so as to rest on the ear.
Abstract: An improved mop with a cleaning cloth which is capable of more effectively cleaning, elongating the life span of a mop, reducing water consumption for cleaning, more rapidly cleaning, and being well applicable to cleaning a car body or an outer wall of a building. The mop includes a plurality of mop rods, and a plurality of thin plate-shaped mop cloths which are stacked by a mop cloth assembling member.
Abstract: The description relates to a process for the production of aqueous chlorine dioxide solutions through oxidation of chlorite with oxo acids and/or oxo acid anions having a suitable redox potential in a buffered aqueous medium, wherein an acidic aqueous solution A is produced which has a pH of about 5 or less and contains the oxo acids and/or oxo acid anions, and the acidic aqueous solution A is mixed with an aqueous chlorite solution B to form chlorine dioxide, wherein a pH of less than 6.95 is adjusted in the reaction mixture, this pH value being stabilized by a buffering system contained therein.
August 23, 1999
Date of Patent:
August 15, 2000
Manfred Rimpler, Fritz Kueke, Marcus Rimpler
Abstract: An apparatus and method for determining optimal locations for placing radioactive seeds at a cancerous site. After a plurality of cross-sectional images of the cancerous site are obtained, a contour of an area on each cross-sectional image of the cancerous site is defined and transferred to a three-dimensional coordinate system. Then, a population of locations within each area of each cross-sectional image of the cancerous site where radioactive seeds can be placed is identified. A genetic algorithm is then implemented to determine the optimal number of locations within the cancerous site to place the radioactive seeds.
Abstract: In a microscope such as for the examination of specimens in specimen vessels, a device for changing objectives is provided. The microscope includes at least a first objective. The device comprises an arrangement for providing an operating control so that the at least first objective can be raised and lowered vertically and is displaceable horizontally vertical to an optical axis of the microscope.
October 8, 1998
Date of Patent:
July 25, 2000
Carl Zeiss Jena GmbH
Dieter Schau, Hans Brinkmann, Peter Dietrich
Abstract: In an antiskid chain, a side holder has a closure for connecting the two free first and second ends of a shackle strand, each of which ends is provided with a thickened portion. The shackle strand can rest against the side of a vehicle tire and serves to fasten the running netting of the antiskid chain by means of fastening hooks. The closure is formed of a molded part which has a central, substantially plate-shaped portion, both of whose ends located opposite one another are bent toward the plate underside while forming an open, approximately cylindrical interior space. Tabs which are likewise bent downward from both longitudinal sides of the molded part are provided directly adjacent to the bend. Two tabs which are located opposite to one another are inclined approximately in a roof-shaped manner relative to one another in cross section. The molded part having a slit in the center in the longitudinal direction.
Abstract: Proposed is a novel connector for display inspection of a liquid crystal display panel, by which the display panel per se can be inspected before mounting of a driver IC chip thereon to greatly improve the productivity of the display inspection.
Abstract: An optical head assembly comprises a laser light source, an objective lens for converging laser light rays emitted from the laser light source at an optical recording medium, a hologram element placed in the optical path between the laser light source and the objective lens, an optical detector for signaling that detects returning light rays from the optical recording medium and an optical detector for monitoring that detects a portion of the laser beams emitted from the laser source toward the optical recording medium. The hologram element has first and second diffraction areas; the first diffraction area diffracting the returning light rays to guide them to the optical detector for signaling; the second diffraction area reflecting and diffracting a portion of the light rays emitted from the laser light source at a fringe-like reflecting portion to guide them to the optical detector for monitoring.
Abstract: Pyrroloindole derivatives having antimicrobial and antitumor activities and having a carbamoyloxy group represented by the following general formula (1), optical isomers thereof, and pharmacologically acceptable salts thereof; and intermediates for production thereof: ##STR1## where R.sup.1 is OH, or a pyrrolidinyl group; n is 1 or 2; R.sup.2 is a lower alkyl group of C.sub.1 -C.sub.4 ; X--Y or Y--X is CH.sub.2, CHOH, CH.sub.2 -CH.sub.2, O--CH.sub.2, or NMe--CH.sub.2 ; Z.sup.1 is Cl or Br; and Ar.sup.1 is ##STR2## wherein Z.sup.2 and Z.sup.3 are O or NH; m is 0 or an integer of 1 to 4; and Ar.sup.2 is any of the above groups a, b, c, and d.
Abstract: A lighting device includes a body and one or more light sources that introduce light into the body. The one or more light sources include at least one strip-like source which continuously emits light with respect to its longitudinal direction. The body light has a light exit face on one side and by which light introduced into the body passes out of the body. The strip-like source is directly fitted on or in the body in such a way that the light which passes out of a side of the strip-like light source facing the body substantially completely enters the body. The body has a lateral face at least partly constructed as a mirror or reflector for light traveling in the body and at least partly to the light exit face.