Abstract: A haemolysator having a sonotrode plate and oscillation generating elements acting thereupon, wherein the oscillation generating elements are set into mechanical oscillations by an electrical AC-signal generator. The haemolysater also includes a sample chamber to which the sonotrode plate transmits mechanical oscillations, and has oscillation generating elements that are excitable toward mechanical oscillations in a wide frequency band.

Abstract: Disclosed are apparatus and methods for loading images. A request can be received at a computing device to display a plurality of images on the computing device. In response to the request, the computing device can load, in parallel, the plurality of images into storage of the computing device. The computing device can determine whether an image of the plurality of images is to be used. In response to determining that the image is to be used, the computing device can mark the image as loaded. In response to determining that the image is to not be used, the computing device can mark the image as no-image. Only images marked as loaded can be provided for display.

Abstract: A biological sample such as a tissue section is stained with one or more quantum dots and possibly other fluorophores (total number of fluorophores N). A camera coupled to a microscope generates an image of the specimen at a plurality of different wavelengths within the emission spectral band of the N fluorophores. An analysis module calculates coefficients C1 . . . CN at each pixel from the set of images and reference spectral data for the N fluorophores. The coefficients C1 . . . CN are related to the concentration of each of the individual fluorophores at each pixel location. Morphological processing instructions find biological structures, e.g., cells, cellular components, genes, etc., in the images of the specimen. Quantitative analysis is performed on the identified biological structures. A display module displays the quantitative analysis results to the user, along with images of the specimen. The images can include images constructed from one or more of the coefficients C1 . . . CN.

Abstract: Methods and compounds for production of cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV are provided.

Abstract: A system and method for providing a linear spread in an electronic trading environment are described. According to one example embodiment, a trading system can receive market information associated to a trading strategy, known as a spread. The trader may also define a market volatility parameter to utilize in the calculation of a linear spread price axis. The received market information and a divide spread algorithm are also used to determine the linear spread price axis. The trading application determines a linear spread price axis, at which price levels are separated by consistent linear tick increments. The linear spread price axis allows for more efficient and effective trading in the electronic trading environment especially when certain tradeable objects are traded or when certain spread algorithms, like the divide spread algorithm, are utilized.

Abstract: A system and methods for dynamically changing a trade order quantity in an electronic trading environment are described herein. According to one example embodiment, an automated trading tool determines if a leaned on quantity of a trading strategy has increased or decreased and if so, dynamically changing a desired order quantity to reflect the change in the leaned on quantity. Dynamically changing an order quantity may be more profitable for a trader as order queue position may be maintained and portion of the desired order quantity may get filled; rather than a trader losing their order queue position and/or taking a chance of not getting any of their order quantity filled.

Abstract: A respirator assembly e.g. for NBC protection is formed from two separate sub-assemblies. The first sub-assembly comprises a flexible hood (or other suitable headgear), a rigid mounting ring and a peripheral face seal. The second sub-assembly comprise a face plate with lens, oronasal mask and inlet and outlet valves, and is demountably attachable to the ring. The first sub-assembly can be worn on its own with the user breathing ambient air through the front end, the second sub-assembly being added if and when a hazard is encountered. The positioning of the face seal in the first sub-assembly means that a comfortable and reliable fit can be ensured when the sub-assembly is donned prior to a mission, but the user is relieved of the physiological burden of wearing the complete respirator unless and until protection is required.

Abstract: A nozzle for producing a single-file stream of droplets of a fluid, methods using the nozzle, and an injector, comprising the nozzle of the invention, for providing the single-file stream of droplets of a fluid to a high-vacuum system are described. The nozzle comprises two concentric tubes wherein the outer tube comprises a smoothly converging-diverging exit channel and the outlet end of the first tube is positioned within the converging section of the exit channel.

Abstract: A computer-based method for determining a set of equity-indexed crediting parameters E for a lifetime-income equity-indexed deposit product provided to a set of owners having a set of dates of birth B, a rider charge C, a lifetime income percentage scale L, a set of profitability requirements R, a principal amount P, and an account value A. The method can include the steps of: establishing the values of C, L, R, P, A and E at a time when said deposit product is purchased; generating a set of yield curve and equity index scenarios consistent with valuation parameters; setting a trial value Ei for E; calculating the observed distribution D of profitability; comparing D with R; and, computing a revised trial value Ei+1 for E, where the steps of establishing, generating, setting, calculating, comparing, and computing are performed by at least one general purpose computer.

Abstract: A microscope for performing an opthalmo-surgical intervention, in particular for a contactless wide-angle observation of an eye during an intervention, is provided. The microscope has a tube (1a) having an objective and an ocular, a holding arm (1), at which the tube (1a) is attached such that a movement of the objective with respect to the holding arm (1) along the optical axis of the objective is possible, an optical accessory part (8a) between the objective and the eye and a holding device for the optical accessory part (8a). The holding device for the optical accessory part is attached at the holding arm (1) by means of an attachment device (2) in such a way that the holding device does not take part in movements of the objective along the optical axis of the objective. Thereby, when changing the picture angle, a re-adjustment is highly simplified.

Abstract: The connector provides fewer connections and attachments to a breastpump configured for expressing breast milk from both of a woman's breasts simultaneously, thereby facilitating easier use of the breast pump and yielding fewer pieces for the user to carry or misplace. The connector includes a manifold with four ports. Individual tubes extend from three of the four ports and each has a plug member. One tube engages with a vacuum source and the remaining two tubes engage with a breastshield assembly for double breast pumping. When single breastpumping is desired, one of the two tubes connected to the breastpump assemblies is disconnected and engaged with the dock port of the manifold.

Abstract: Human MARK genes are identified as modulators of the PTEN pathway, and thus are therapeutic targets for disorders associated with defective PTEN function. Methods for identifying modulators of PTEN, comprising screening for agents that modulate the activity of MARK are provided.

Abstract: A system and method for trading order priority levels in an electronic trading environment are described. In one embodiment, a trader who is willing to have his order moved from a high priority level to a lower priority level in an order queue may advertise his willingness to do so, and other traders can place bids for the high priority level. In such an embodiment, for example, a bidder who places the highest bid or whose bid is received first may get the high priority level in the order queue in exchange for the paid fee.

Abstract: As market conditions descend or ascend an axis of prices, the display of market information is repositioned, at a pre-determined rate if desired, around an item of interest. An item of interest may include the best bid price, the best ask price, the inside market, a moving average, a last traded price, a theoretical value, the result of an equation, or some other item of interest to the trader. According to the present embodiments, market information may be displayed in a region relative to an axis of prices, and when an event occurs, a repositioning signal is initialized causing the axis to be repositioned such that the item of interest is positioned at a pre-determined location in the region. The price axis can be repositioned at a fixed rate or at a dynamically variable rate.

Abstract: The present application discloses systems and methods for accessing digital content between multiple devices. The systems and methods may be directed to providing access to an interaction with a first application on a head-mounted display (HMD) to a second device. Contextual information relating information of the HMD and information associated with the interaction to describe an interaction state may be stored. A second device may be selected upon which the interaction state may be accessed and a determination of attributes of the second device may be made. The HMD may transfer to the second device the stored contextual information such that the second device may provide via the second application access to the interaction state. Information associated with a user input to the first application may also be transferred. In one example, the contextual information may describe an identified occurrence of digital content accessed via the first application.

Abstract: The present invention is directed to a collapsible food guard for displaying and serving food comprising a resilient transparent cover assembly for a substantially planar base. The cover assembly is substantially semi-cylindrical of a predetermined radius and has closed opposing ends. The cover assembly is reversibly pivotably attached to a base and has downward facing edges to seal the cover to the base when the cover is pivoted in the down (closed) position. The semi-cylindrical portion of the cover assembly is a resilient transparent shield that reversibly detachable from the arched surfaces of the closed opposing ends (side walls) and is sufficiently resilient such that when detached form the arched surfaces of the opposing side walls, it assumes the substantially planar shape in which it was initially molded. This resiliency allows the collapsible food guard to collapse into planar elements (side walls, shield and optional base) requiring minimal storage space and providing easy cleaning.

Abstract: The present invention relates to processes for preparing gaseous products, and in particular methane, via the catalytic hydromethanation of a carbonaceous feedstock in the presence of steam, syngas and an oxygen-rich gas stream.

Abstract: A biosensor based upon a vertically emitting, distributed feedback (DFB) laser is disclosed. In one configuration, the DFB laser comprises a replica-molded, one- or two-dimensional dielectric grating coated with a laser dye-doped-polymer as the gain medium. A sensor is also described in which the grating layer and the active layer are combined into a single layer. DFB lasers using an inorganic or organic thin film with alternating regions of high and low index of refraction as the active layer are also disclosed. The sensor actively generates its own narrowband high intensity light output without stringent requirements for coupling alignment, thereby resulting in a simple, robust illumination and detection configuration.

Abstract: The present invention relates to a medication delivery device, to dosing mechanisms suitable for use in medication delivery devices, in particular in pen-type injectors, preferably having dose setting means and a drive device enabling the administration of a medicinal product from a multi-dose medication cartridge, to a use of such device, and to a method of manufacturing or assembling such device.

Abstract: Disclosed is a process for preparing polymer conjugates of agricultural, therapeutic, and food additive compounds using Mitsunobu conditions.