Abstract: Technologies are described herein for boot caching to accelerate boot access in a data storage system providing boot consolidation. Boot caching may be provided to improve boot access for multiple clients concurrently booting from a common storage server. Boot statistics may be collected per user or client. The boot statistics can determine common patterns within the boot procedures of the clients and may be used to compute boot caching tables. These tables may then be used during boot caching to accelerate booting of clients. A boot caching mechanism can be implemented to support improved booting performance by caching data blocks common to multiple booting volumes. This approach can leverage the condition that much of the data loaded by clients at boot time may be substantially identical, because booting can involve loading the same operating system components into each client.

Abstract: An antibody of the invention interacts with human DR5 to produce agonistic or antagonistic effects downstream of the receptor including inhibition of cell proliferation and apoptosis. Nucleic acid sequences and amino acid sequences of anti-DR5 antibodies have been elucidated and vectors and cells containing and expressing these sequences have been generated. Methods and uses for the antibodies are detailed including treatment of apoptosis-related disease and treatment of dysregulated cell growth.

Abstract: The invention relates to solids powders comprising particles having an average particle size of 0.1 to 50 ?m with predominantly a core-shell structure, wherein the core comprises at least one water-insoluble fatty acid salt and the shell at least one anionic, cationic or non-ionic emulsifier, and the solids powder when introduced into water or at least one polar organic solvent or a mixture comprising water and at least one polar organic solvent, at a temperature of 23° C. while exposed to a mechanical force, forms a complete dispersion within 60 minutes or less.

Abstract: The present invention is directed to methods for inducing desired activity in enzymes or microorganisms capable of producing the enzymes. The invention is further directed to methods of stabilizing activity in microorganisms. In specific embodiments, the invention provides methods for inducing and stabilizing nitrile hydratase activity, amidase activity, and asparaginase I activity. The invention further provides compositions comprising enzymes or microorganisms having induced and/or stabilized activity.

Abstract: Technologies are described herein for providing networked RAID in a virtualized storage cluster. The storage capacity of a storage cluster having two or more storage nodes is organized into tiers. A portion of the available storage capacity is allocated to one tier that is organized using chained declustering. Another portion of the available storage capacity is allocated to another tier that is organized using a networked RAID configuration. The storage cluster monitors the frequency at which data in the storage cluster is accessed. Frequently used data that is stored in the network RAID-configured tier is promoted to the chained declustered-configured tier. Infrequently used data that is stored in the chained declustered-configured tier is demoted to the network RAID-configured tier. The zone size for zones stored in the chained declustered-configured tier may be different than for zones stored in the network RAID-configured tier.

Abstract: Methods, systems, and computer-readable media for transmitting data between a local computer and a remote computer are provided. An amount of data capable of being transmitted per frame from the local computer to the remote computer is determined. An amount of data associated with a current frame of data to be transmitted to the remote computer is also determined. A quality level for the data to be transmitted to the remote computer is then selected such that the amount of the data to be transmitted to the remote computer is less than or equal to the amount of data capable of being transmitted per frame to the remote computer.

Abstract: Described herein are nitrated lipids and methods of making and using the nitrated lipids.

Abstract: Disclosed herein is a process for purifying aryl carboxylic acids, in particular terephthalic acid, wherein the impure acid is dissolved or dispersed in an ionic liquid and a non-solvent is added to precipitate the purified acid. The present disclosure further relates to compositions comprising terephthalic acid and one or more ionic liquids.

Abstract: Technologies are provided for integrating a caching module into a data storage system architecture. A request to perform an I/O operation is received at the caching module from an initiator. The caching module provides a notification to a storage driver that the request will be delivered to the storage driver in the future. The storage driver then determines whether the request can be satisfied. If the storage driver determines that it will be able to satisfy the I/O request, the storage driver can optimize the allocation and placement of the I/O request before receiving the actual I/O request. When the caching module subsequently sends the actual I/O request to the storage driver, the storage driver utilizes the previously allocated space and optimized placement to perform the requested I/O operation.

Abstract: The present invention provides a method of detecting adventitious agents in a composition comprising a microorganism by using ribozyme-expressing indicator cells, as well as indicator cells useful in such detection.

Abstract: Systems and methods of enabling or disabling functionality in a web browser or browser-based application are disclosed. An example method of controlling the functionality of an application program can include: contacting a server to request content; receiving a response from the server including the requested content and a token that is a text string embedded in the response; decrypting said token; interpreting information contained in said token to determine which features of the application program are available for displaying the requested content; and invoking a level of functionality in said application program in accordance with said token to make the features for displaying the requested content available. The token can be a digital certificate based on the server's domain name or an encrypted hash of the server's domain name.

Abstract: The invention relates to an apparatus for displacing tissue within the body, wherein the apparatus includes two or more attachment members selectively displaceable with respect to each other via a driving member. The driving member preferably is rotatable and is caused to rotate by manually activating an actuator by applying a depressing force from outside the body.

Abstract: Novel histone deacetylase inhibitors, including novel fluorescent histone deacetylase inhibitors, are described. Methods for making and using the same, e.g., to treat cancer, are provided.

Abstract: The invention is a method of treating, restoring or sealing a surface comprising applying an emulsion comprising a latex polymer, a cationic emulsifier, and optionally a recycling agent to the surface to wet the surface and depositing a surface treatment layer on the surface, wherein the depositing step occurs while the surface is wetted. The invention also includes a surface pretreatment composition comprising water, at least one acrylic latex polymer, an aromatic recycling agent, and at least one cationic emulsifier. Furthermore, the invention includes the surface resulting from the application of the emulsion used in the invention and concentrated emulsions for use with the surface treatment composition.

Abstract: Technologies are described herein for providing assisted asynchronous replication between a first storage server having a first current state and a second storage server having a second current state. An instruction to roll back a first storage server from the first current state to a previous state according to a previous snapshot is received. The first storage server is then rolled back from the first current state to the previous state according to the previous snapshot. A determination is made as to whether the previous snapshot is available on a second storage server. Assistance data is then retrieved. A last consistency point common to the first storage server and the second storage server based on the assistance data is identified, where the last consistency point is at or prior to the previous snapshot. The second storage server is rolled back from the second current state to the last consistency point.

Abstract: The present invention is directed to a transconnector for joining adjacent longitudinal spinal rods. The transconnector preferably includes a bridge member and a pair of bone fixation coupling elements, the bridge member is preferably sized and configured to span a distance between the pair of bone fixation coupling elements. The bone fixation coupling elements are preferably sized and configured to engage the bridge member and sized and configured to receive one of the bone fixation elements. The bone fixation coupling elements are preferably sized and configured to engage the body portion of the bone fixation element. The bone fixation coupling elements may include a locking cap having a first set of threads for threadably engaging the bone fixation element.

Abstract: A method for texture characterization is provided. Multi-dimensional spectrum data are determined by transforming multi-dimensional image data into Fourier domain. The multi-dimensional spectrum data are partitioned into a plurality of partitions, wherein each partition is associated with a predetermined set of orthogonal voice frequencies. The partitioned multi-dimensional spectrum data are then transformed into Stockwell domain resulting in discrete orthonormal Stockwell transform data. The discrete orthonormal Stockwell transform data are then processed to determine data associated with image texture, which are indicative of a feature of the object.

Abstract: Provided are systems operable to effect a temporary change in a modulation transfer function (MTF) of a target imaging system. The systems include a light source operable to produce light for transient propagation onto at least a portion of the target imaging system, a power source in operative communication with the light source and configured to effect the production of light from the light source, and a transmission unit in operative communication with the light source and configured to propagate the produced light onto at least a portion of the target imaging system. The propagated light is configured for absorbance by the portion of the target imaging system; the absorbance causes an increase in temperature and a change in a refractive index profile of at least the portion of the imaging system. The change in refractive index profile produces a temporary change in the MTF of the imaging system.

Abstract: Technologies are described for implementing container space management (CSM) in a data storage system. Performance may be improved by ensuring that the maximum number of drive spindles is made available to I/O loads. This may be accomplished by distributing data equally amongst all drive spindles, even if the drive spindles are in different logical drives. A workflow analysis may be performed to determine when the I/O load on the storage system is low and thus identify preferred times for background data re-striping. Data may be re-striped in a minimum number of movements using a data placement algorithm and data placement maps to select data to be re-striped. The data may be re-striped such that the most frequently accessed data within a tier is moved first. Such re-striping can be performed in a manner which optimizes the performance of the storage system both during, and after, the re-striping process.

Abstract: The present invention provides compositions and methods of use thereof to prevent and/or treat pathogenic infection. In particular, the present invention provides the use of kinase inhibitors to inhibit kinases that involve in pathogen-host cell interactions that are associated with or cause pathogenic infections, therefore, to effectively prevent and/or treat pathogenic infections with far less likely to engender resistance as compared to conventional antibiotics and anti-viral drugs. The present invention further provides the use of kinase inhibitors for the treatment of acute pathogenic infections for a short period of time to avoid toxicities that may caused by long term use of these kinase inhibitors.