Patents Represented by Attorney Morris L. Nielsen

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  • Substituted tolyl esters of PGA.sub.2
    Patent number: 3932486
    Abstract: Substituted phenyl and naphthyl esters of PGA.sub.2, 15-alkyl-PGA.sub.2, and 15(R)-15-alkyl-PGA.sub.2, and their racemic forms, and processes for producing them are disclosed. The products are useful for the same pharmacological and medical purposes as PGA.sub.2, 15-alkyl-PGA.sub.2, and 15(R)-15-alkyl-PGA.sub.2, and are also useful as a means for obtaining highly purified PGA.sub.2, 15-alkyl-PGA.sub.2, and 15(R)-15-alkyl-PGA.sub.2 products.
    Type: Grant
    Filed: December 12, 1974
    Date of Patent: January 13, 1976
    Assignee: The Upjohn Company
    Inventor: Walter Morozowich
  • 11.beta.-PGE.sub.2 compounds
    Patent number: 3931284
    Abstract: Novel methods are disclosed for transforming PGA.sub.2 and 15.beta.-PGA.sub.2 and their acetates, methyl esters, and acetate methyl esters to various prostanoic acids and esters of the PGE.sub.2 and PGF.sub.2.sub..alpha. series. Some of the latter are novel and are useful for the same pharmacological purposes as PGE.sub.2 and PGF.sub.2.sub..alpha..
    Type: Grant
    Filed: July 8, 1974
    Date of Patent: January 6, 1976
    Assignee: The Upjohn Company
    Inventors: John E. Pike, William P. Schneider
  • 5-Oxa prostaglandin F.sub.2.sub..alpha. analogs
    Patent number: 3931279
    Abstract: 5-Oxa prostaglandin-type compounds and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, labor inducement at term, and wound healing.
    Type: Grant
    Filed: May 21, 1973
    Date of Patent: January 6, 1976
    Assignee: The Upjohn Company
    Inventor: Norman A. Nelson
  • Substituted tolyl esters of PGE.sub.1
    Patent number: 3931285
    Abstract: Substituted phenyl and naphthyl esters of PGE.sub.1, 15-alkyl-PGE.sub.1, and 15(R)-15-alkyl-PGE.sub.1, and their racemic forms, and processes for producing them are disclosed. The products are useful for the same pharmacological and medical purposes as PGE.sub.1, 15-alkyl-PGE.sub.1, and 15(R)-15-alkyl-PGE.sub.1, and are also useful as a means for obtaining highly purified PGE.sub.1, 15-alkyl-PGE.sub.1, and 15(R)-alkyl-PGE.sub.1 products.
    Type: Grant
    Filed: December 12, 1974
    Date of Patent: January 6, 1976
    Assignee: The Upjohn Company
    Inventor: Walter Morozowich
  • Substituted anilide ester of PGA.sub.2
    Patent number: 3931281
    Abstract: Substituted anilide esters of PGA.sub.2, 15-alkyl-PGA.sub.2, and 15(R)-15-alkyl-PGA.sub.2, and their racemic forms, and processes for producing them are disclosed. The products are useful for the same pharmacological and medical purposes as PGA.sub.2, 15-alkyl-PGA.sub.2, and 15(R)-15-alkyl-PGA.sub.2, and are also useful as a means for obtaining highly purified PGA.sub.2, 15-alkyl-PGA.sub.2, and 15(R)-15-alkyl-PGA.sub.2 products.
    Type: Grant
    Filed: January 8, 1974
    Date of Patent: January 6, 1976
    Assignee: The Upjohn Company
    Inventor: Walter Morozowich
  • 11.beta.-PGF.sub.2.sub..beta. compounds
    Patent number: 3931283
    Abstract: Novel methods are disclosed for transforming PGA.sub.2 and 15.beta.-PGA.sub.2 and their acetates, methyl esters, and acetate methyl esters to various prostanoic acids and esters of the PGE.sub.2 and PGF.sub.2.sub..alpha. series. Some of the latter are novel and are useful for the same pharmacological purposes as PGE.sub.2 and PGF.sub.2.sub..alpha..
    Type: Grant
    Filed: July 8, 1974
    Date of Patent: January 6, 1976
    Assignee: The Upjohn Company
    Inventors: John E. Pike, William P. Schneider
  • 3-Oxa phenyl-substituted PGE compounds
    Patent number: 3931289
    Abstract: This invention is a group of 3-oxa and 4-oxa phenyl-substituted PGE type, PGF type, PGA type and PGB type compounds, and processes for making those. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, labor inducement at term, and wound healing.
    Type: Grant
    Filed: April 11, 1974
    Date of Patent: January 6, 1976
    Assignee: The Upjohn Company
    Inventor: Gordon L. Bundy