Abstract: A topical antiperspirant composition containing an antihistamine selected from the group consisting of antazoline, pyrilamine, tripelennamine, diphenhydramine, phenindamine and their corresponding pharmaceutically acceptable salts and an enhancer for said antihistamine selected from the group consisting of sodium sulfate, glutamic acid; octyl palmitate and propylene glycol methyl ether.

Abstract: A pharmaceutical composition and process for administering non-steroidal drugs which are protected against injury to the gastrointestinal tract by a combination of certain H.sub.1 and H.sub.2 receptor blockers.

Abstract: An antiperspirant process and composition wherein the active antiperspirant ingredient is an alpha adrenergic amine that has at least a substantial alpha.sub.2 adrenergic amine activity component.

Abstract: A plane adapted to cut hinge recesses in a door edge is disclosed. The plane housing has a base having a cutout. A rotary cutter, rotatable relative to the base, is mounted from the base and in alignment with the cutout. Means are provided for selectively adjusting the position of the cutter relative to the base. Limiting means are provided for preventing the cutter from cutting across the entire width of an underlying door edge so that the cutter will leave an uncut strip of door edge after a hinge recess is cut in the door edge by the plane. The uncut strip serves to limit lateral movement of the door hinge when it is mounted in the hinge recess cut by the plane. Means are provided for rotating the cutter, such means comprising a first pulley on the cutter, a second pulley, a tensioned belt engaging both pulleys and drive means for the second pulley.

Abstract: 6-Aminonicotinic acid is reacted with an alkali carbonate selected from the group consisting of sodium carbonate and potassium carbonate. The reaction is carried out at elevated temperature and in dimethylformamide. The 6-aminonicotinic acid alkali salt so produced is reacted with 3-chloromethylpyridine hydrochloride. The reaction is carried out at elevated temperature and in dimethylformamide. The desired nicotinyl ester is thus produced.

Abstract: Procedure for treating acne vulgaris that uses salicylic acid and benzoyl peroxide either sequentially or simultaneously. Compositions for practicing each of these aspects of the invention are also described.

Abstract: Procedure for treating acne vulgaris that uses salicylic acid and benzoyl peroxide either sequentially or simultaneously. Compositions for practicing each of these aspects of the invention are also described.

Abstract: 1-Phenethylimidazole compounds of the formula: ##STR1## wherein R.sup.1 and R.sup.2 are independently hydrogen or halogen, Z is a mono or disubstituted phenyl moiety of the formula: ##STR2## or a 2 or 3-thienyl moiety of formula: ##STR3## wherein R.sup.3 and R.sup.4 are independently hydrogen, halogen, (lower) alkyl, or trifluoromethyl, with the proviso that R.sup.3 and R.sup.4 can not both be trifluoromethyl and the antimicrobial acid addition salts thereof are useful as antifungal and antibacterial agents.

Abstract: Reaction of 4-nitrophenacyl bromide with morpholine affords the novel intermediate 1-(4-nitrophenyl)-2-morpholinylethanone which when reduced yields the novel sunscreen 1-(4-aminophenyl)-2-morpholinylethanone.

Abstract: Various derivatives of barbituric acid and of diphenylhydantoin are described in which alkoxymethyl or benzyloxymethyl groups are attached to the nitrogen atoms of the rings. Therapeutic compositions containing these compounds and their use as anti-convulsant agents are described.

Abstract: A 1-(2-acylaminophenyl)imidazole of formula: ##STR1## wherein R.sup.5 is a cycloaliphatic, phenyl, substituted phenyl group bonded to the carbonyl carbon through a carbon-to-carbon linkage are intermediates for the preparation of 4-substituted imidazo[1,2-a]quinoxalines having anti-inflammatory, immunosuppressant and anti-fungal activity.

Abstract: A method for treating inflammatory disorders in mammals which comprises administering to said mammals having an inflammatory disorder a therapeutically effective amount of 4-trifluoromethylimidazo[1,2-a]quinoxaline.

Abstract: 2(1-imidazolyl)phenylureylene compounds of the formula: ##STR1## wherein R.sup.2 is hydrogen or a radical bonded to the nitrogen by a carbon to nitrogen linkage and selected from the group consisting of aliphatic, cycloaliphatic, phenyl, substituted phenyl, fused bicyclic aryl, and monocyclic aryl substituted aliphatic groups are intermediates for the preparation of 4-substituted amino imidazo[1,2-a]quinoxalines having immunosuppressant activity.

Abstract: A 4-substituted imidazo [1,2-a]quinoxaline of formula: ##STR1## or a pharmaceutically acceptable salt thereof wherein R.sup.1 is bonded to a ring carbon through a carbon-to-carbon linkage and is an aliphatic, cycloaliphatic, substituted phenyl, fused bicyclic aryl; or a monocyclic aryl substituted aliphatic group.

Abstract: Preparation of 4-substituted imidazo[1,2-a]quinoxalines by cyclizing a compound of the formula: ##STR1## with phosphorous oxychloride wherein X.sup.2 is a group --R.sup.5 or --NHR.sup.2 where R.sup.5 and R.sup.2 are hydrogen or various organo groups.

Abstract: A 4-substituted imidazo[1,2-a]quinoxaline of formula: ##STR1## or a pharmaceutically acceptable salt thereof wherein R.sup.2 is hydrogen or a radical bonded to the nitrogen by a carbon to nitrogen linkage and selected from the group consisting of aliphatic, cycloaliphatic, phenyl, substituted phenyl, fused bicyclic aryl, and monocyclic aryl substituted aliphatic group.

Abstract: A method for reducing the immunological response in mammals by the administration of certain substituted phenyl or substituted anilino imidazo[1,2-a]quinoxalines.

Abstract: A method for treating a fungal infection in mammals which comprises administering to said mammals having a fungal infection a therapeutically effective amount of a 4-(substituted phenyl)imidazo[1,2-a]quinoxaline.

Abstract: A 1-(2-acylaminophenyl)imidazole of formula: ##STR1## wherein R.sup.5 is hydrogen or an aliphatic, cycloaliphatic, phenyl, substituted phenyl, fused bicyclic aryl or monocyclic aryl substituted aliphatic group bonded to the carbonyl carbon through a carbon-to-carbon linkage. The compounds are useful as intermediates in the preparation of 4-substituted imidazo[1,2-a]quinoxalines.