Abstract: A color image forming method is disclosed, comprising exposing a silver halide color photographic material and developing the exposed photographic material at 43 to 180° C. to form a color image, wherein at least one light-sensitive layer comprising a silver halide emulsion comprising tabular silver halide grains having an average aspect ratio of at least 8. There is also disclosed a digital image forming process, wherein image recording information of the photographic material which was formed by use of the color image forming method is coverted to digital image information through an image sensor.
Type:
Grant
Filed:
May 15, 2003
Date of Patent:
June 8, 2004
Assignee:
Konica Corporation
Inventors:
Hiromoto Ii, Hiroyuki Hoshino, Noriyuki Kokeguchi
Abstract: The present invention relates to compounds of formula (I), in which B, D, E, G, X, Y, Z, R1, R2 and s have the meanings indicated in the claims, their physiologically tolerable salts and their prodrugs. The compounds of formula (I) are valuable pharmacologically active compounds. They are vitronectin receptor antagonist and inhibitors of cell adhesion and are suitable for the therapy and prophylaxis of illnesses which are based on the interaction between vitronectin receptors and their ligands in cell-cell or cell-matrix interaction processes or which can be prevented, alleviated or cured by influencing such interactions. For example, they can be applied for inhibiting bone resorption by osteoclasts and thus for treating and preventing osteoporosis, or for inhibiting undesired angiogenesis or prolifertion of cells of the vascular smooth musculature.
Type:
Grant
Filed:
March 6, 2002
Date of Patent:
June 8, 2004
Assignees:
Aventis Pharma Deutschland GmbH, Genetech Inc.
Inventors:
Anuschirwan Peyman, Jochen Knolle, Thomas R Gadek, Jean-Francois Gourvest, Jean-Marie Ruxer
Abstract: The present invention relates to single-chain antigen-binding molecules capable of glycosylation. Compositions of, genetic constructions coding for, and methods for producing monovalent and multivalent single-chain antigen-binding molecules capable of glycosylation are described and claimed. Composition of, genetic constructions coding for, and methods for producing glycosylated monovalent and multivalent single-chain antigen-binding molecules capable of polyalkylene oxide conjugation are described and claimed. The invention also relates to methods for producing a polypeptide having increased glycosylation and the polypeptide produced by the described method. Uses resulting from the multifunctionality of a glycosylated/polyalkylene oxide conjugated antigen-binding protein are also described and claimed.
Type:
Grant
Filed:
September 20, 2001
Date of Patent:
June 1, 2004
Assignee:
Enzon, Inc.
Inventors:
David Filpula, Maoliang Wang, Robert Shorr, Marc Whitlow, Lihsyng S. Lee
Abstract: The present invention relates to single-chain antigen-binding molecules capable of glycosylation. Compositions of, genetic constructions coding for, and methods for producing monovalent and multivalent single-chain antigen-binding molecules capable of glycosylation are described and claimed. Composition of, genetic constructions coding for, and methods for producing glycosylated monovalent and multivalent single-chain antigen-binding molecules capable of polyalkylene oxide conjugation are described and claimed. The invention also relates to methods for producing a polypeptide having increased glycosylation and the polypeptide produced by the described method. Uses resulting from the multifunctionality of a glycosylated/polyalkylene oxide conjugated antigen-binding protein are also described and claimed.
Type:
Grant
Filed:
September 20, 2001
Date of Patent:
June 1, 2004
Assignee:
Enzon, Inc.
Inventors:
David Filpula, Maoliang Wang, Robert Shorr, Marc Whitlow, Lihsyng S. Lee
Abstract: The present invention relates to novel 3-nitropyridine derivatives, pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same as active ingredients. Methods of preparing the derivatives and pharmaceutical compositions containing the same are also disclosed. The 3-nitropyridine derivatives of the present invention, due to their inhibitory activity against the proliferation of human immunodeficiency virus (HIV) as well as hepatitis B virus (HBV), can be used as therapeutic agents as well as preventive agents for hepatitis B and acquired immune deficiency syndrome (AIDS).
Type:
Grant
Filed:
May 24, 2002
Date of Patent:
June 1, 2004
Assignee:
Dong Wha Pharm. Ind. Co. Ltd.
Inventors:
Sung June Yoon, Sang Wook Lee, Nam Doo Kim, Yong Kyun Park, Geun Hyung Lee, Jong Woo Kim, Sang Jin Park, Hee Jeoung Park, Dong Hyuk Shin
Abstract:
The present invention relates to compounds of formula (1), in which H, G, Z, X, Y, r, s and t have the meanings indicated in the claims, their physiologically tolerable salts and their prodrugs. The compounds of formula (1) are valuable, pharmacologically active compounds. They are vitronectin receptor antagonists and inhibitors of cell adhesion and are suitable for the therapy and prophylaxis of illnesses which are based on the interaction between vitronectin receptors and their ligands in cell-cell or cell-matrix interaction processes or which can be prevented, alleviated or cured by influencing such interactions. For example, they can be applied for inhibiting bone resorption by osteoclasts and thus for treating and preventing osteoporosis, or for inhibiting undesired angiogenesis or proliferation of cells of the vascular smooth musculature.
Type:
Grant
Filed:
March 20, 2002
Date of Patent:
June 1, 2004
Assignees:
Aventis Pharma Deutschland GmbH, Genentech Inc.
Inventors:
Anuschirvan Peyman, Karl-Heinz Scheunemann, Thomas R Gadek, Jean-Francois Gourvest, Jean-Marie Ruxer
Abstract: A film for a liquid crystal display comprising a fatty acid celluose ester film having an acetyl group and a propionyl group is disclosed. Sum of degree of acetyl substitution (DSac) and degree of propionyl substitution (DSpr) of the fatty acid celluose ester film of the film is 2.8 or less, and a retardation value (Rt value) in the thickness direction defined by Formula 1 is 60 to 300 nm.
Abstract: There is described an organic thin-film transistor fabricated on a substrate. The organic thin-film transistor includes a first insulating layer formed on the substrate; an organic semiconductor layer formed on the first insulating layer; a second insulating layer formed on the organic semiconductor layer; a first through-hole bored through the second insulating layer; a second through-hole bored through the second insulating layer; a source electrode embedded in the first through-hole, a depth of which is equal to or greater than a thickness of the second insulating layer so that the source electrode contacts the organic semiconductor layer; a drain electrode embedded in the second through-hole, a depth of which is equal to or greater than a thickness of the second insulating layer so that the drain electrode contacts the organic semiconductor layer; and a gate electrode embedded in the first insulating layer.
Abstract: A method for processing a silver halide photographic light-sensitive material which comprises a support, a silver halide emulsion layer provided on the support and a hydrophilic colloid layer adjacent to the silver halide emulsion layer, comprising a step of developing the photographic light-sensitive material with a developing solution containing an ascorbic acid compound as a developing agent, wherein the photographic material contains an amine compound in at least one of the silver halide emulsion layer and the hydrophilic colloid layer and an nucleating agent within a range of 0 to 20 mg per 1 m2 of the photographic light-sensitive material, and wherein the amine compound has a distribution coefficient (log P) of 1 or more in a n-octanol/water system.
Abstract: The invention relates to a process for preparing cyclohexanedicarboxylic esters (hexahydrophthalic diesters) by esterifying the corresponding benzenedicarboxylic acids and immediately hydrogenating the esterification mixture in the presence of nickel catalysts.
Type:
Grant
Filed:
June 3, 2002
Date of Patent:
May 25, 2004
Assignee:
Celanese Chemicals Europe GmbH
Inventors:
Hans Bohnen, Thomas Klein, Klaus Bergrath
Abstract: Disclosed is a printing plate precursor comprising a substrate and provided thereon, a layer containing a light heat conversion material, wherein the light heat conversion material does not substantially change in nature when allowed to stand in a temperature atmosphere of 400 to 500° C. for 10 minutes or a printing plate precursor comprising a substrate and provided thereon, a hydrophilic layer which is porous, wherein the hydrophilic layer contains a carbon atom-free material in an amount of not less than 91% by weight.
Abstract: The invention concerns the field of biochemistry, and more precisely biological substances of vegetable origin. The invention concerns substances having non-cytotoxic biological activity, extracted from plants with CAM metabolism, such as plants of the Cactacees, Crassulacees and Saxifragacees family. The invention also concerns the method for obtaining these substances as well as compositions containing them. Said compositions are designed for accelerating and amplifying the synthesis of thermal shock proteins of cells of living beings in vivo or in vitro.
Type:
Grant
Filed:
January 25, 2002
Date of Patent:
May 18, 2004
Assignee:
INOVAT S.A.R.L.
Inventors:
Gilles Gutierrez, Mostafa Serrar, Lionel Viornery, James Norton
Abstract: A next textile treatment where the present method can be used to remove contaminants from the textile concerns rewashing. As already observed above, after dyeing textile with reactive dyestuffs, a considerable amount of dyestuff, particularly hydrolyzed dyestuff, is left behind on the textile. Because the hydrolyzed dyestuff is not fast to washing, it should be removed to provide a textile with sufficient washing fastness. In a rewashing treatment of textile dyed with reactive dyestuff, the textile is first rinsed with water to remove alkali and salt. Thereupon, it is rewashed, with the fructan polycarboxylic acid being metered in the form of a 25-40% solution in an amount of 1-3 g/l of water. Rewashing preferably takes place at a temperature of 95-100° C. for a period of 10-30 minutes. After rewashing, the textile is again rinsed with water to remove residues of the hydrolyzed reactive dyestuff.
Type:
Grant
Filed:
March 30, 2001
Date of Patent:
May 18, 2004
Assignee:
Coƶperatie Cosun U.A.
Inventors:
Hendrika Cornelia Kuzee, Henricus Wilhelmus Carolina Raaijmakers, Mariette Ellen Boukje Bolkenbaas, Antonius Jacobus Gerardus Maria Kaarsgaren, Johannes Kooi, Hildegonda Petronella Maria Fliervoet
Abstract: An ink-jet recording sheet comprising a first porous layer at the outermost position of the ink-jet recording sheet, wherein the ink-jet recording sheet satisfies the following Formula (1), when an aqueous solution, which comprises a water-soluble alcohol-type organic solvent having an SP value in an range of from 18.414 to 30.69 (MPa)½ and a boiling point of not less than 120° C. in an amount of from 10 to 40%, is provided to the surface of the ink-jet recording sheet in an amount of 20 ml/m2,
Vc/Vd≦0.4 Formula (1)
wherein each of Vc and Vd represents a water transition amount of a first area, where the aqueous solution is provided, and a second area, where the aqueous solution is not provided, respectively, during a contact time of 0.8 seconds when the recording material is subjected to Bristow's Measurement.
Abstract: A humidification device for polymeric membrane fuel cell stacks fed with gaseous reactants is disclosed. The gases supplied to the stack are previously fed in admixture with a stream of liquid water to a chamber filled with a reticulated material, whose highly subdivided geometry provides an extended exchange surface favouring the saturation of gas. The device is more efficient and compact than those known in the art.
Type:
Grant
Filed:
October 9, 2001
Date of Patent:
May 18, 2004
Assignee:
Nuvera Fuel Cells Europe S.r.l.
Inventors:
Gabriele Mazzucchelli, Massimo Brambilla, Gian Piero Fleba, Antonio Maggiore
Abstract: An extruding coating method comprises steps of feeding a coating liquid into a coating liquid reservoir section provided with a slit having a slit width; and extruding the coating liquid through the slit so as to conduct coating, wherein the coating liquid is extruded through the slit by pushing the coating liquid in the coating liquid reservoir toward all over the slit width by a piston.
Abstract: This invention relates to a powder or toner accommodating container. This container is a powder or toner accommodating container having at least one engaging portion between a container main body and an accessory component to be mounted on the container main body, wherein the container includes a gas releasing function of releasing a gas in the container outside the container when a pressure difference between the interior and exterior of the container exceeds a predetermined value.
Abstract: The present invention relates to water-resistant aqueous dispersion adhesives with prolonged pot life and good color constancy of their bonds, comprising homopolymeric and/or copolymers polyvinyl esters, polymeric protective colloids, water-soluble compounds which can be complexed with the polymeric protective colloids, and derivatives of glyoxal and polyaldehydes having at least 3 carbon atoms, from which aldehyde groups can be controllably released in acidic media. The inventive dispersion adhesives are suitable for adhesively bonding porous and semiporous substrates.
Abstract: A subject of the invention is the compounds of formula (I):
in which:
X represents a CH2 or SO2 radical or an oxygen atom, Y represents a (CH2)m—(CH═CH)n(CH2)o radical, with m+n+o≦8, n=0 or 1, Ar represents an aryl radical,
W represents a hydrogen atom, or the remainder of a carbamate function.
The compounds of formula (I) have useful antibiotic properties.
Type:
Grant
Filed:
April 19, 2001
Date of Patent:
May 18, 2004
Assignee:
Aventis Pharma S.A.
Inventors:
Constantin Agouridas, Jean-Francois Chantot