Abstract: Disclosed are an instantaneous boiler and a double pipe heat exchanger for the instantaneous boiler supplying heating water and hot water, which can obtain hot water output larger than heating water output, simultaneously use the heating water and the hot water, and have a simple piping structure. The heat exchanger includes: an outer pipe used for a hot water pathway, to which combustion heat is directly transferred from a burner in a combustion chamber; and an inner pipe used for a heating water pathway and extending through the outer pipe.

Abstract: The present invention provides methods of enhancing the efficacy and specificity of RNA silencing. The invention also provides compositions for mediating RNA silencing. In particular, the invention provides siRNAs, siRNA-like molecules, shRNAs, vectors and transgenes having improved specificity and efficacy in mediating silencing of a target gene. Therapeutic methods are also featured.

Abstract: A steering head for use with a casing, the steering head having a generally cylindrical body with a first body end with a lead edge, a second body end with a rear edge, and a body surface extending from the lead edge to the rear edge, an outer tube with an internal side generally facing the body surface, the outer tube extending from the first body end to the second body end, and a steering flap disposed on an external side of the outer tube having a first flap face facing radially inwardly and a second flap face facing radially outwardly. A biased hinge is secured to both the outer tube and the steering flap, the biased hinge being operative to retract the steering flap into a retracted position from an extending position.

Abstract: A fuel cell stack includes a plurality of power generation cells stacked in a direction of gravity. In a cathode side separator of the power generation cell, an oxygen-containing gas discharge passage is connected to an oxygen-containing gas flow field, and a water guide member is provided for the oxygen-containing gas discharge passage for allowing condensed water to be directly dropped in the direction of gravity along the oxygen-containing gas discharge passage. The water guide member is a plate member protruding into the oxygen-containing gas discharge passage and inclined toward the direction of gravity.

Abstract: An apparatus for driving a loadable device component, the apparatus including: the loadable device component providing an application with a loading mechanism that is classified according to a load type property; a core framework module component defining a kind of the load type property; at least one eXtensible Markup Language (XML) data component containing configuration information and generation information of the loadable device component; and a device manager component driving a corresponding loadable device component after parsing the XML data component.

Abstract: Materials and Methods for reducing cell proliferation or extracellular matrix production in a mammal are disclosed. The methods comprise administering to a mammal a composition comprising a therapeutically effective amount of a zvegf4 antagonist in combination with a pharmaceutically acceptable delivery vehicle. Exemplary zvegf4 antagonists include anti-zvegf4 antibodies, inhibitory polynucleotides, inhibitors of zvegf4 activation, and mitogenically inactive, receptor-binding variants of zvegf4. The materials and methods are useful in the treatment of, inter alia, fibroproliferative disorders of the kidney, liver, and bone.

Abstract: A humidifier for humidifying a fuel cell composed of an anode side humidifier and a cathode side humidifier each possessing a plurality of hollow fiber membrane modules for migrating moisture between a supply gas, which is supplied to a fuel cell, and an exhaust gas, which is exhausted from the fuel cell to thereby humidify the supply gas, the humidifier comprising: a pair of heads which hold both ends of the hollow fiber membrane modules, a connecting member which connects each of heads, and a device for warming the supply gas composed of conduits through which a cooling medium exhausted from the fuel cell is passed. The device for warming the supply gas is configured so that first warms a humidifier at an outlet side of the supply gas, and then warms a humidifier at an inlet side of the supply gas.

Abstract: The invention relates to neutralizing antibodies, and antibody fragments thereof, having high potency in neutralizing hCMV, wherein said antibodies and antibody fragments are specific for one, or a combination of two or more, hCMV gene UL products. The invention also relates to immortalized B cells that produce, and to epitopes that bind to, such antibodies and antibody fragments. In addition, the invention relates to the use of the antibodies, antibody fragments, and epitopes in screening methods as well as in the diagnosis, prevention, and therapy of disease.

Abstract: A proton conductor is formed of a porous body as a substrate and proton-conducting polymer covalently bonded to inner surfaces of pores of the porous body. The proton-conducting polymer comprises a main chain and a plurality of branched side chains extending radially therefrom. The branched side chains are each bonded to a proton-conducting salt at the end. The proton-conducting polymer has a substantially cylindrical structure in which the salts can be circumscribed by a virtual circle having a center on the cross-sectional center of the main chain such that a radial direction of the virtual circle is perpendicular to a longitudinal direction of the main chain. The salts are located on the peripheral wall of the substantially cylindrical structure. Protons are transferred between the adjacent salts, so that a conduction channel is formed on the peripheral wall of the cylindrical structure.

Abstract: Disclosed herein is a decay heat removal system, including: a decay heat exchanger that absorbs decay heat generated by a nuclear reactor; a heat pipe heat exchanger that receives the decay heat from the decay heat exchanger through a sodium loop for heat removal and then discharges the decay heat to the outside; and a sodium-air heat exchanger that is connected to the heat pipe heat exchanger through the sodium loop and discharges the decay heat transferred thereto through the sodium loop to the outside. According to the decay heat removal system, a heat removal capability can be realized by the heat pipe heat exchanger at such a high temperature at which the safety of a nuclear reactor is under threat, and a cooling effect can be obtained through the sodium-air heat exchanger at a temperature lower than that temperature.

Abstract: A rain gutter cover comprising an elongate cover member adapted to be situated over an open trough of a rain gutter. The cover member has a first cover portion integrally extending into a second water directing portion following a rounded nose portion. An outer surface of the elongate cover member is adapted to substantially cause water passing thereover to adhere to its surface even under light rainfall conditions. The first portion includes ribs forming multiple channels configured to converge water on the first portion and facilitate initial water adherence to the nose area and to the surface of the second portion.

Abstract: A plug valve has a valve body, a cage fitted within the valve body and a rotatable plug housed within a cylindrical cavity in the cage, for controlling fluid flow through the valve. The cage has first and second opposed flat side surfaces, each side surface has a port for receiving a replaceable flow-path insert in a fluid-tight seal. In one embodiment, the plug also includes at least one inset seal for sealing the at least one of the ports when the plug is in a closed position to inhibit leakage through the valve at low fluid pressures.

Abstract: An automatic identification system for communicating identifying information by coupling signals through the human body is provided. The system includes a battery powered identification device that transmits an identifying signal via a modulated carrier. The identification device is coupled to the body of the user via a coupling plate. The signal from the identification device is received by a reading device that is also coupled to the body of the user via a coupling plate. The reading device may display and/or enunciates the identifying information to the user. The coupling technique, carrier frequency, and construction of the devices are such that the identification information is not inadvertently radiated or coupled to unintentional users or receivers.

Abstract: The invention relates to neutralizing antibodies and antibody fragments having high potency in neutralizing hCMV, wherein said antibodies and antibody fragments are specific for a combination of hCMV proteins UL130 and UL131A, or for a combination of hCMV proteins UL128, UL130 and UL131A. The invention relates also to immortalized B cells that produce, and to epitopes that bind to, such antibodies and antibody fragments. In addition, the invention relates to the use of the antibodies, antibody fragments, and epitopes in screening methods as well as in the diagnosis and therapy of disease.

Abstract: This invention demonstrates that KRC molecules have multiple important functions as modulating agents in regulating a wide variety of cellular processes including bone formation and mineralization. TGF-? signaling in osteoblasts promotes the formation of a multimeric complex between KRC, Runx2, Smad3, and the E3 ubiquitin ligase, WWP1 which inhibits Runx2 function due to the ability of WWP1 to promote Runx2 polyubiquitination and proteasome-dependent degradation. Furthermore, KRC and WWP1 form a complex with RSK2 which promotes RSK2 phosphorylation and inhibits RSK2 function due to the ability of WWP 1 to promote RSK2 ubiquitination. Methods for identifying modulators of KRC activity are provided. Methods for modulating an immune response, bone formation and mineralization, and KRC-associated disorders using agents that modulate KRC expression and/or activity are also provided.

Abstract: An integrated system for modeling, simulating and analyzing chemical and biochemical reactions includes a modeling environment for constructing a model of a chemical or biochemical reaction. The system also includes a simulation engine accepting as input said constructed model of the chemical or biochemical reaction and generating as output an expected result for a first chemical reaction using a first type of computational model and an expected result for a second chemical reaction using a second type of computational model. An analysis environment communicates with the simulation engine and displays the expected result.

Abstract: A vacuum-actuated shear valve coupled between piping from a storage tank and piping internal to a fuel dispenser that automatically opens and closes in response to a vacuum level. A vacuum actuator is provided to control a fuel flow valve inside the shear valve. When a sufficient vacuum level is generated to the vacuum actuator, the actuator keeps the flow path valve inside the shear valve open. When the vacuum is lost, the vacuum actuator releases the flow path valve inside the shear valve, which closes it. The vacuum actuator is coupled to a secondary containment space of a fuel-handling component that is drawn under a vacuum level by a vacuum-generating source to monitor for leaks. Thus, if a leak occurs in the monitored secondarily contained space, the shear valve is automatically closed to prevent the flow of fuel from continuing to be supplied to the source of the leak.

Abstract: Systems and methods are disclosed relating to a system including a launch tube and a generator connected with the launch tube. The generator uses multiphase materials (MPM) and compressed air to convert kinetic energy of the MPM into electrical energy.

Abstract: An electric system has a fuel cell for generating electric power by being supplied with a reactive gas, an electric storage device having a voltage lower than a voltage output from the fuel cell, a first power supply line connected to the fuel cell, a second power supply line connected to the electric storage device, a first electric accessory serving as at least part of a fuel cell accessory for operating the fuel cell, a first DC-to-DC converter for performing bidirectional voltage conversion between the first power supply line and the second power supply line and a second DC-to-DC converter for lowering a voltage for supply electric power to the first electric accessory.

Abstract: The present invention relates to a stationary user detecting system and method and a call admission control method using the same in a wireless communication system. A plurality of base stations located in the wireless Internet system detect a stationary user at regular time intervals and maintain it by a predetermined number of cases for each terminal. Information on the maintained stationary user is recalculated with a stationary probability for each base station so as to be used for call admission control. Therefore, the terminal of the stationary user detected in the wireless Internet system is calculated with the stationary probability value, which is applied to the call admission control, thereby minimizing reservation of undesired resources.