Patents Represented by Attorney, Agent or Law Firm Nields, Lemack & Dingman
  • Patent number: 6232346
    Abstract: This invention provides a dietary supplement comprising L-Carnitine (or its functional analogues such as Acetyl-Carnitine or Proprionyl-1-Carnitine), Coenzyme Q10 and Taurine for the correction of the abnormality in mitochondrial energetics in cardiac failure and certain other diseases. A high protein nutritional feeding supplementation with Cysteine, Creatine, Vitamin E (RRR-d-alpha-tocopherol), Vitamin C (ascorbic acid), Selenium, and Thiamin in may be added.
    Type: Grant
    Filed: October 7, 1999
    Date of Patent: May 15, 2001
    Inventors: Michael J. Sole, Khursheed N. Jeejeebhoy
  • Patent number: 6187783
    Abstract: A novel phenanthridinium derivative represented by general formula (A): wherein R1 is a substituted or unsubstituted lower aliphatic hydrocarbon group; R is an aliphatic hydrocarbon chain having 2 to 6 carbon atoms which may optionally be substituted with a substituent selected from the group consisting of a lower alkyl group, a halogen and a hydroxy group; each of Y and Z independently represents a hydrogen, a hydroxy or a lower alkoxy group; or Y and Z are combined together to form methylenedioxy or a phenyl ring; and, X− is an acid residue or a hydrogen acid residue, exhibits an antitumor activity and has resistance to chemical reduction as well as biological metabolic reactions and is thus advantageous for use as a medicine.
    Type: Grant
    Filed: May 20, 1999
    Date of Patent: February 13, 2001
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Akira Masuda, Masato Suwa, Masanobu Suzuki
  • Patent number: 6184253
    Abstract: Disclosed is use of nonsteroidal anti-estrogen compounds such as toremifene citrate as active ingredient for treating autoimmune diseases.
    Type: Grant
    Filed: November 16, 1998
    Date of Patent: February 6, 2001
    Assignees: Nippon Kayaku Kabushiki Kaisha, Orion-yhtyma Oy
    Inventors: Junpei Itoh, Osamu Miyazaki, Hisao Ekimoto, Michinori Koyama, Tetsushi Saino, Lauri Kangas, Anni Warri, Christer Granberg
  • Patent number: 6159249
    Abstract: In the dyeing of hydrophobic fibers comprising new synthetic fibers, especially those called micronfine fibers, etc., it is difficult to obtain a dyed product having excellent fastness and it is further difficult to obtained a dyed product excellent also in color rendering. The present invention solved the problem as following:A specific dye composition containing a water-insoluble monoazo disperse dye represented by a specific structural formula is used to dye hydrophobic fibers, especially polyester fibers, comprising micronfine fibers, thereby giving a dyed products excellent in fastness balance and color rendering.
    Type: Grant
    Filed: April 22, 1999
    Date of Patent: December 12, 2000
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Yasuo Murakami, Yoshiyuki Sato, Tsuyoshi Kikkawa
  • Patent number: 6137567
    Abstract: The laser survey instrument according to the present invention comprises a rotary laser device and a photodetector for receiving a laser beam, wherein the rotary laser device comprises a light source unit for emitting the laser beam, a rotator for projecting the laser beam toward the photodetector by rotary irradiation, detection means for detecting status of the rotary laser device, and a control unit for changing the number of rotations of said rotator based on the result of detection from the detection means in order to transmit the detection result from the detection means to the photodetector, the photodetector comprises a photodetection unit for receiving the laser beam from the rotary laser device and for issuing a photodetection signal, display means having a display corresponding to the photodetection signal, and judging means for detecting the number of rotations of the laser beams from the photodetection signal of the photodetection unit and for operating the display means according to the rotating
    Type: Grant
    Filed: September 23, 1998
    Date of Patent: October 24, 2000
    Assignee: Kabushiki Kaisha TOPCON
    Inventors: Mitsutoshi Ohoka, Kazuki Osaragi, Jun-ichi Kodaira
  • Patent number: 6136448
    Abstract: A recording material, more particularly for ink-jet printers, comprises an inking layer formulated to locally receive a water-soluble pigment solution and containing an epoxy cross-linkable, carboxyl-grouped cationic mixed polymer, an epoxidized metal oxide and a water-soluble polymer.
    Type: Grant
    Filed: April 3, 1998
    Date of Patent: October 24, 2000
    Assignees: FEW Forschungs- und Entwicklungsgesellschaft Wolfen mbH, EMTEC Magnetics GmbH
    Inventors: Christoph Roth, Angela Kuhrt, Ursula Sell
  • Patent number: 6130746
    Abstract: A system or method for electronically simulating fabrics to assist in grading yarn and fabric qualities, in which the diameter or other qualities of one or more yarn samples along the total length of the samples is measured, and representations of the measured yarn qualities are evaluated in a fabric pattern to assist evaluation of the effects of the yarn quality variations on fabric which potentially would be produced from the sampled yarn.
    Type: Grant
    Filed: February 21, 1996
    Date of Patent: October 10, 2000
    Assignee: Lawson-Hemphill, Inc.
    Inventors: Avishai Nevel, Kendall W. Gordon, Jr., David Bonneau
  • Patent number: 6126759
    Abstract: This invention is to provide a steel sheet for 2-piece battery cans, which has excellent formability in DI molding to give thin-walled, side body parts, and, more preferably, a steel sheet for 2-piece battery cans, which, after having been formed into cans, has high mechanical strength and excellent anti-secondary work embrittlement with excellent corrosion resistance. The steel sheet for 2-piece battery cans of the invention contains S and O (where O is the total oxygen content) while satisfying the conditions that S is from 0.005 to 0.015 wt. %, preferably from 0.005 to 0.012 wt. %, that 0 is from 0 to 0.0025 wt. % and that [S/10+O].ltoreq.0.0035 wt. %, preferably [S/10 +0].ltoreq.0.0030 wt. %. More preferably, the steel sheet contains B of from 0.0005 to 0.0015 wt. % while satisfying 0.2.ltoreq.B/N.ltoreq.1.0, or contains either one or both of Cr of being from 0.03 to 0.10 wt. % and Ni of being from 0.01 to 0.10 wt. %, the total of the two being not larger than 0.10 wt. %.
    Type: Grant
    Filed: October 9, 1997
    Date of Patent: October 3, 2000
    Assignee: NKK Corporation
    Inventors: Yoshihiro Hosoya, Katsumi Tanikawa, Katsumi Kojima, Takashi Awaya, Hirohide Furuya
  • Patent number: 6123849
    Abstract: A chromatography column having at least one central slurry valve positioned at either the top cell assembly and/or the bottom cell assembly. The central slurry valves have a pneumatically actuated valve sleeve which can be shifted to create two different flow configurations. One flow configuration allows for the simultaneous cleaning in place of the flow path used to charge the column with chromatography media and the separate processing of fluid through the chromatography media. The other flow configuration permits the reslurrying and removal of chromatography media from the column, and the subsequent repacking of the column with fresh chromatography media without disassembling the column and the provision of venting the column in the event of overpressurization during packing.
    Type: Grant
    Filed: May 21, 1999
    Date of Patent: September 26, 2000
    Assignee: Millipore Corporation
    Inventor: Geoffrey John Purdom
  • Patent number: 6124059
    Abstract: The invention relates to microporous battery separators based on an essentially homogeneous mixture of a thermoplastic polymer, an inert filler and optionally a plasticizer. The separators contain, as filler, pyrogenic silica in a quantity of more than 20 vol. % and optionally one or more further fillers, so that the filler content overall is more than 60 up to a maximum of 82 vol.-%. The separators are suitable in particular for the manufacture of sealed accumulators.
    Type: Grant
    Filed: September 1, 1998
    Date of Patent: September 26, 2000
    Assignee: Daramic, Inc.
    Inventors: Werner Bohnstedt, Jorg Deiters, Klaus H. Ihmels, Jurgen Ruhoff
  • Patent number: 6124420
    Abstract: This invention provides a novolak type epoxy resin which has low melt viscosity but shows high heat resistance when hardened. Particularly, it relates to a novolak type epoxy resin in which the relationship between the total % by weight of 3 to 6 nucleus bodies and the melt viscosity measured by a cone plate method at 150.degree. C. satisfies specified conditions, an epoxy resin composition containing the same and hardened products thereof.
    Type: Grant
    Filed: December 5, 1997
    Date of Patent: September 26, 2000
    Assignees: Nippon Kayaku Kabushiki Kaisha, Gun Ei Chemical Industry Co., Ltd.
    Inventors: Kenichi Kuboki, Yoshio Shimamura, Ryoichi Hasegawa, Yoshiaki Kurimoto, Akiyuki Kojima, Yukio Abe
  • Patent number: 6123961
    Abstract: A method for treating or preventing urinary incontinence and other motility disorders involving the urethrogenital tract, by administering to a mammal an effective amount of the R-isomers of 4-diethylamino-2-butynyl cyclohexylphenylglycolate and 4-ethylamino-2-butynyl cyclohexylphenylglycolate and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: September 23, 1997
    Date of Patent: September 26, 2000
    Assignee: Bridge Pharma, Inc.
    Inventor: A. K. Gunnar Aberg
  • Patent number: 6120939
    Abstract: Battery separator comprising a consolidated nonwoven mat of ultrafine polymeric fibers in which at least 10% of said fibers have a diameter less than 1 micron and which mat has an average pore size of less than 3 .mu.m. The fiber mat is formed by meltblowing using modified conditions to produce a self-bonded web having the desired content of ultra fine fibers.
    Type: Grant
    Filed: January 13, 1998
    Date of Patent: September 19, 2000
    Assignee: Daramic, Inc.
    Inventors: J. Kevin Whear, Werner Bohnstedt, Eric M. Peters
  • Patent number: 6121195
    Abstract: Methods and compositions for enhancing plant growth provide for foliar application of a substance which enhances the accumulation of formyltetrahydropteroyl polyglutamate (C.sub.1 -THF) in a treated plant. Treatment with substances that contribute to the structure of C.sub.1 -THF increase the rate and quantity of carbon fixation by the plant. Thereafter, plant growth is further improved either by exposure of the plant to elevated oxygen, illumination and heat or by foliar input of single carbon fragment sources. Optimal results are obtained by combined treatment with a substance that can serve as a sink for C.sub.1 fragments produced in the leaf.
    Type: Grant
    Filed: December 7, 1998
    Date of Patent: September 19, 2000
    Inventors: Arthur M. Nonomura, John N. Nishio, Andrew A. Benson
  • Patent number: 6120858
    Abstract: Provided is a black sealant for liquid crystal cell comprising (a) an epoxy resin, (b) a novolac resin, (c) a curing accelerator and (d) a titanium-type black pigment. The use of the black sealant for liquid crystal cell of the present invention can provide a liquid crystal cell which prevents light leakage of the liquid crystal cell from the sealed portion, which has a high electrical insulation property and which is excellent in an adhesion strength and a humidity resistance.
    Type: Grant
    Filed: July 28, 1998
    Date of Patent: September 19, 2000
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Masahiro Hirano, Masaki Shinmoto, Shigeru Matsuyama, Akira Ishii
  • Patent number: 6117133
    Abstract: A multiple-lumen sheath which fits over a resectoscope and provides an electrosurgical resection energy (radio frequency) return path and at least one irrigant channel, comprising, a sheath body which fits over the resectoscope; a conductor disposed within the sheath body for carrying the electrosurgical resection energy; and an irrigant channel within the sheath body and outside of the conductor, for both carrying irrigant fluid and cooling the conductor.
    Type: Grant
    Filed: March 26, 1999
    Date of Patent: September 12, 2000
    Inventor: Stephen M. Zappala
  • Patent number: 6117317
    Abstract: A chromatography column having at least one central slurry valve positioned at either the top cell assembly and/or the bottom cell assembly. The central slurry valves have a pneumatically actuated valve sleeve which can be shifted to create three different flow configurations. One flow configuration allows for the simultaneous cleaning in place of the flow path used to charge the column with chromatography media and the separate processing of fluid through the chromatography media. The other flow configurations permit the reslurrying and removal of chromatography media from the column, and the subsequent repacking of the column with fresh chromatography media without disassembling the column.
    Type: Grant
    Filed: May 23, 1997
    Date of Patent: September 12, 2000
    Assignee: Millipore Investment Holdings Limited
    Inventors: Nicola Jane Dickson, Neil Frazer
  • Patent number: 6117207
    Abstract: A process for recovering metal from spent catalyst, containing at least a metal component, comprising providing a heated, liquid metal bath, at a temperature sufficient to melt the metal in the spent catalyst, and create off gas from any volatile non-metal catalyst components, adding spent catalyst to the bath, collecting off gas from the bath, transporting the collected off gas to a gas cooler, and maintaining the off gas during the transportation at a temperature of at least about 875.degree. F.; rapidly cooling the off gas to less than about 275.degree. F. in no more than about 0.15 seconds, to prevent the formation of dioxin; and withdrawing melted metal from the bath, for reuse as catalyst.
    Type: Grant
    Filed: July 9, 1998
    Date of Patent: September 12, 2000
    Inventor: Constantine Miserlis
  • Patent number: 6114282
    Abstract: A heat-sensitive recording material in which a heat-sensitive color-developing layer comprising, as the main components, a usually colorless or light-colored color former and a developer capable of developing the color former upon heating on a support, characterized by comprising, as the developer, crystals of 3,3'-diallyl-4,4'-dihydroxy-diphenyl sulfone which have DSC (Te) of at least 149.degree. C. and which are of a crystal form characterized by an X-ray diffraction pattern having peaks at least at diffraction angles (2.theta.) [.degree.] of 7.2 and 22.0, obtained by an X-ray powder diffractometry using Cu--K.alpha. rays. This heat-sensitive recording material is high in sensitivity, little in Discoloration of the ground in heat and moisture and excellent in image durability.
    Type: Grant
    Filed: January 11, 1999
    Date of Patent: September 5, 2000
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Masao Onishi, Masaaki Saito, Hirofumi Iwamoto
  • Patent number: 6114364
    Abstract: The present invention relates to a compound represented by the following general formula (1) ##STR1## (wherein X represents O, S, SO, SO.sub.2, or NH, Y is a substituted or unsubstituted hydrocarbon residue containing 1 through 6 carbon atoms and having an overall molecular weight of not less than 15 and not more than 400, and the hydrocarbon residue, when the residue is ring, may contain one or two hetero-atoms in the ring, and Z is a carboxyl group, a group derived therefrom or an aliphatic hydrocarbon residue having from 1 to 4 carbon atoms which may be substituted or unsabstituted) or a pharmacologically acceptable salt thereof (excluding (1R,2S)-2-[(2R)-(2-acetyl-amino-2-carboxyethyl)thiomethyl]-3-oxo-1-cyclope ntane-carboxylic acid (cystacyclin)), a method for production thereof and a medicinal use thereof. The compound of the present invention is useful as a neuron differentiation accelerator.
    Type: Grant
    Filed: October 5, 1998
    Date of Patent: September 5, 2000
    Assignee: Nippon Kayaku Co., Ltd.
    Inventors: Seiichi Saito, Tomio Morino, Kuniko Masuda