Patents Represented by Attorney Paul D. Burgauer

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  • Catalyst for making polyurethanes
    Patent number: 4421673
    Abstract: Polyurethane foams with excellent physical properties can be obtained by using a partial salt between N,N-dimethylaminopropane-1,3-diamine (DMAPA) and a branched octanoic acid.
    Type: Grant
    Filed: April 9, 1981
    Date of Patent: December 20, 1983
    Assignee: Abbott Laboratories
    Inventors: Francis W. Arbir, Daniel S. Raden, Kenneth W. Narducy, Francois M. Casati
  • Catalyst for making polyurethanes
    Patent number: 4366084
    Abstract: Polyurethane foams with excellent physical properties can be obtained by using a partial salt between N,N-dimethylaminopropane-1,3-diamine (DMAPA) and phenol.
    Type: Grant
    Filed: May 26, 1981
    Date of Patent: December 28, 1982
    Assignee: Abbott Laboratories
    Inventors: Francis W. Arbir, Daniel S. Raden, Kenneth W. Narducy
  • Inhibitors of transpeptidase
    Patent number: 4347355
    Abstract: New .beta.-lactams of the general structure: ##STR1## wherein R represents H or an acyl moiety known from the penicillin or cephalosporin art, R' is hydrogen, loweralkoxy, loweralkoxyalkyl, loweralkyl, phenylthio or loweralkylmercapto R" is loweralkyl, the broken line represents an optional double bond, and acyloxymethyl esters thereof. All compounds are effective antibacterials.
    Type: Grant
    Filed: December 1, 1980
    Date of Patent: August 31, 1982
    Assignee: Abbott Laboratories
    Inventor: Daniel T. Chu
  • Erythromycin base tablets
    Patent number: 4340582
    Abstract: An enteric coated erythromycin tablet is provided that produces essentially the same blood levels in fasting and nonfasting subjects. The tablet contains erythromycin base dihydrate and a highly water-soluble nontoxic salt in the core and the coating polymer is a hydroxypropyl methylcellulose phthalate.
    Type: Grant
    Filed: January 15, 1981
    Date of Patent: July 20, 1982
    Assignee: Abbott Laboratories
    Inventors: Douglas C. Kriesel, Shashi P. Mehta
  • 1-Acryloyl-3-(substituted)phenyl ureas
    Patent number: 4332821
    Abstract: 1-Acryloyl-3-(substituted)phenyl ureas have been found to be highly effective as fungicides when incorporated into or applied to agricultural media, plastics, paints or the like.
    Type: Grant
    Filed: September 15, 1980
    Date of Patent: June 1, 1982
    Assignee: Abbott Laboratories
    Inventors: John W. Williams, Frank C. Becker
  • Ovicides
    Patent number: 4318920
    Abstract: It has been found that substituted aminoacetonitriles of the structure ##STR1## wherein X and Y, independently, stand for hydrogen, halogen, loweralkyl, loweralkyloxy, nitro or CF.sub.3 ; R is hydrogen or methyl; and R' is hydrogen or loweralkyl are excellent insect ovicides.
    Type: Grant
    Filed: February 8, 1979
    Date of Patent: March 9, 1982
    Assignee: Abbott Laboratories
    Inventor: Robert G. Stein
  • 2-Hydroxylaminomethyl phenols
    Patent number: 4312887
    Abstract: It has been found that certain 4-substituted 2-hydroxylaminomethyl phenols or their nontoxic pharmaceutically acceptable acid addition salts are excellent diuretic, saluretic and anti-inflammatory agents.
    Type: Grant
    Filed: October 25, 1978
    Date of Patent: January 26, 1982
    Assignee: Abbott Laboratories
    Inventor: Fortuna Haviv
  • Antibacterial peptides
    Patent number: 4309342
    Abstract: It has been found that dipeptides containing a 3-fluoro-D-alanine N-terminus are powerful antibacterials and produce a highly useful synergistic effect with antibiotics.
    Type: Grant
    Filed: July 3, 1980
    Date of Patent: January 5, 1982
    Assignee: Abbott Laboratories
    Inventors: Daniel T. Chu, Jerry R. Martin, Alford M. Thomas
  • Biocidal chelate
    Patent number: 4307109
    Abstract: The biocidal activity of N-(2-methyl-1-naphthyl)-maleimide is vastly improved by chelating it with an amine wherein each free hydrogen on each amino group has been replaced by the groups --(CH.sub.2).sub.n COOY wherein n represents 1 or 2 and each Y represents hydrogen, ammonium or an alkali metal cation.
    Type: Grant
    Filed: May 8, 1980
    Date of Patent: December 22, 1981
    Assignee: Abbott Laboratories
    Inventors: Francis W. Arbir, William J. Rizoff, Frank C. Becker
  • Antiviral pyrazolopyrazines
    Patent number: 4303658
    Abstract: Certain 1-substituted-3-loweralkyl-5-(substituted)phenyl-6-aminopyrazolo[3,4-b]pyr azines are provided. They have useful activity as antivirals.
    Type: Grant
    Filed: May 12, 1980
    Date of Patent: December 1, 1981
    Assignee: Abbott Laboratories
    Inventors: Gerard Y. Paris, Mina D. Perlin, Andre G. Pernet, Nathan L. Shipkowitz
  • Biocidal additive for cutting fluids
    Patent number: 4294853
    Abstract: The addition of a combination of CH.sub.3 SO.sub.2 CHI.sub.2 and certain chelating agents to cutting fluid prevents bacterial and fungal growth. Concentrated aqueous co-dispersions thereof are particularly useful.
    Type: Grant
    Filed: June 3, 1980
    Date of Patent: October 13, 1981
    Assignee: Abbott Laboratories
    Inventors: John W. Williams, Robert A. Smith, Francis W. Arbir
  • Process for rigid foams of improved friability
    Patent number: 4293658
    Abstract: Polyurethanes based on a resole-type polyol can be significantly improved in their friability when the urethane catalyst is a fully neutralized tertiary amine salt and butyl benzyl phthalate is used as the plasticizer.The polyol is prepared by reacting a phenol and formaldehyde under substantially anhydrous conditions with continuous removal of water, and has a water content of no more than about 5%.
    Type: Grant
    Filed: May 12, 1980
    Date of Patent: October 6, 1981
    Assignee: Abbott Laboratories
    Inventors: Daniel S. Raden, Francis W. Arbir
  • Method for protecting industrial substrates from fungal or bacterial attack
    Patent number: 4276090
    Abstract: Method for protecting fabrics, plastics, paints, etc. from fungal and/or bacterial attack comprising treating same with N-(2-methyl-1-naphthyl) maleimide.
    Type: Grant
    Filed: November 13, 1978
    Date of Patent: June 30, 1981
    Assignee: Abbott Laboratories
    Inventors: Frank C. Becker, Jorge P. Li
  • Bis-(2-benzylaminoethyl)-disulfides
    Patent number: 4273940
    Abstract: It has been found that bis(2-benzylaminoethyl)-disulfides with the phenyl rings carrying various simple substituents, are highly effective anti-inflammatories and inhibit chemotaxis of human neutrophils.
    Type: Grant
    Filed: May 13, 1980
    Date of Patent: June 16, 1981
    Assignee: Abbott Laboratories
    Inventors: Fortuna Haviv, George W. Carter
  • Phosphonoacetyl aminoacids
    Patent number: 4272528
    Abstract: Certain phosphonoacetyl aminoacids have been found to be useful antiviral agents suitable to combat herpes virus infection of various types.
    Type: Grant
    Filed: August 14, 1980
    Date of Patent: June 9, 1981
    Assignee: Abbott Laboratories
    Inventors: Anne M. Von Esch, Alford M. Thomas, John S. Fairgrieve, John H. Seely
  • Antihypertensive method
    Patent number: 4269858
    Abstract: 2-Fluoronorepinephrine has been found to have antihypertensive activity when orally administered to warm-blooded animals.
    Type: Grant
    Filed: April 28, 1980
    Date of Patent: May 26, 1981
    Assignee: Abbott Laboratories
    Inventors: John F. DeBernardis, John J. Kyncl
  • Synthesis for 2,3-dichloro-4-(hydroxybenzoyl)phenol
    Patent number: 4268691
    Abstract: By condensation of anisoyl chloride with 2,3-dichloroanisole under proper conditions, 2,3-dichloro-4-(hydroxybenzoyl)phenol is obtained directly.
    Type: Grant
    Filed: August 9, 1979
    Date of Patent: May 19, 1981
    Assignee: Abbott Laboratories
    Inventors: Anthony K. L. Fung, Donald E. Morrison, Andre G. Pernet
  • Antibacterial peptide
    Patent number: 4264590
    Abstract: It has been found that dipeptides containing a 3-halo-D-alanine C-terminus are powerful antibacterials and produce a highly useful synergistic effect with antibiotics.
    Type: Grant
    Filed: June 9, 1980
    Date of Patent: April 28, 1981
    Assignee: Abbott Laboratories
    Inventors: Daniel I. Chu, Jerry R. Martin, Alford M. Thomas, Norman E. Wideburg
  • Salts of erythromycin A esters
    Patent number: 4264765
    Abstract: Highly water-soluble erythromycin A derivatives wherein the desosamine moiety is quaternized with an acyloxy-, benzoyloxy- or alkoxycarbonyl-(or carboxy)-acylmethyl iodide, bromine or chloride and esterified in the 2-position with loweralkyl or --(CH.sub.2).sub.n CO.sub.2 R", wherein R" is H, loweralkyl or substituted loweralkyl and n is an integer from 1-5. These new esters readily convert to erythromycin A upon administration to warm-blooded animals.
    Type: Grant
    Filed: February 20, 1980
    Date of Patent: April 28, 1981
    Assignee: Abbott Laboratories
    Inventors: Nicholas S. Bodor, Leslie A. Freiberg
  • Decarboxylation process
    Patent number: 4262157
    Abstract: Decarboxylation of carboxylic acids using diazabicycloalkenes and, if desired, also a simple copper salt, as the means for decarboxylation.
    Type: Grant
    Filed: March 27, 1980
    Date of Patent: April 14, 1981
    Assignee: Abbott Laboratories
    Inventors: Yuji Hori, Yoshiaki Nagano, Hiroshi Taniguchi